-
2
-
-
84875648021
-
Phosphoinositide 3-kinase and INPP4B in human breast cancer
-
Bertucci M.C., Mitchell C.A. Phosphoinositide 3-kinase and INPP4B in human breast cancer. Ann. N.Y. Acad. Sci. 2013, 1280:1-5.
-
(2013)
Ann. N.Y. Acad. Sci.
, vol.1280
, pp. 1-5
-
-
Bertucci, M.C.1
Mitchell, C.A.2
-
3
-
-
74049107249
-
PI3K pathway activation in breast cancer is associated with the basal-like phenotype and cancer-specific mortality
-
Lopez-Knowles E., O'Toole S.A., McNeil C.M., Millar E.K., Qiu M.R., Crea P., Daly R.J., Musgrove E.A., Sutherland R.L. PI3K pathway activation in breast cancer is associated with the basal-like phenotype and cancer-specific mortality. Int. J. Cancer 2010, 126:1121-1131.
-
(2010)
Int. J. Cancer
, vol.126
, pp. 1121-1131
-
-
Lopez-Knowles, E.1
O'Toole, S.A.2
McNeil, C.M.3
Millar, E.K.4
Qiu, M.R.5
Crea, P.6
Daly, R.J.7
Musgrove, E.A.8
Sutherland, R.L.9
-
4
-
-
53949099847
-
Comprehensive analysis of oncogenic effects of PIK3CA mutations in human mammary epithelial cells
-
Zhang H., Liu G., Dziubinski M., Yang Z., Ethier S.P., Wu G. Comprehensive analysis of oncogenic effects of PIK3CA mutations in human mammary epithelial cells. Breast Cancer Res. Treat. 2008, 112:217-227.
-
(2008)
Breast Cancer Res. Treat.
, vol.112
, pp. 217-227
-
-
Zhang, H.1
Liu, G.2
Dziubinski, M.3
Yang, Z.4
Ethier, S.P.5
Wu, G.6
-
5
-
-
34547172596
-
A transforming mutation in the pleckstrin homology domain of AKT1 in cancer
-
Carpten J.D., Faber A.L., Horn C., Donoho G.P., Briggs S.L., Robbins C.M., Hostetter G., Boguslawski S., Moses T.Y., Savage S., Uhlik M., Lin A., Du J., Qian Y.W., Zeckner D.J., Tucker-Kellogg G., Touchman J., Patel K., Mousses S., Bittner M., Schevitz R., Lai M.H., Blanchard K.L., Thomas J.E. A transforming mutation in the pleckstrin homology domain of AKT1 in cancer. Nature 2007, 448:439-444.
-
(2007)
Nature
, vol.448
, pp. 439-444
-
-
Carpten, J.D.1
Faber, A.L.2
Horn, C.3
Donoho, G.P.4
Briggs, S.L.5
Robbins, C.M.6
Hostetter, G.7
Boguslawski, S.8
Moses, T.Y.9
Savage, S.10
Uhlik, M.11
Lin, A.12
Du, J.13
Qian, Y.W.14
Zeckner, D.J.15
Tucker-Kellogg, G.16
Touchman, J.17
Patel, K.18
Mousses, S.19
Bittner, M.20
Schevitz, R.21
Lai, M.H.22
Blanchard, K.L.23
Thomas, J.E.24
more..
-
7
-
-
78650675585
-
Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers
-
Fedele C.G., Ooms L.M., Ho M., Vieusseux J., O'Toole S.A., Millar E.K., Lopez-Knowles E., Sriratana A., Gurung R., Baglietto L., Giles G.G., Bailey C.G., Rasko J.E., Shields B.J., Price J.T., Majerus P.W., Sutherland R.L., Tiganis T., McLean C.A., Mitchell C.A. Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers. Proc. Natl. Acad. Sci. USA 2010, 107:22231-22236.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 22231-22236
-
-
Fedele, C.G.1
Ooms, L.M.2
Ho, M.3
Vieusseux, J.4
O'Toole, S.A.5
Millar, E.K.6
Lopez-Knowles, E.7
Sriratana, A.8
Gurung, R.9
Baglietto, L.10
Giles, G.G.11
Bailey, C.G.12
Rasko, J.E.13
Shields, B.J.14
Price, J.T.15
Majerus, P.W.16
Sutherland, R.L.17
Tiganis, T.18
McLean, C.A.19
Mitchell, C.A.20
more..
-
8
-
-
84871638844
-
Phosphoinositide 5-phosphatases: how do they affect tumourigenesis?
-
Miyazawa K. Phosphoinositide 5-phosphatases: how do they affect tumourigenesis?. J. Biochem. 2013, 153:1-3.
-
(2013)
J. Biochem.
, vol.153
, pp. 1-3
-
-
Miyazawa, K.1
-
9
-
-
72149091444
-
PIKfyve-ArPIKfyve-Sac3 core complex: contact sites and their consequence for Sac3 phosphatase activity and endocytic membrane homeostasis
-
Ikonomov O.C., Sbrissa D., Fenner H., Shisheva A. PIKfyve-ArPIKfyve-Sac3 core complex: contact sites and their consequence for Sac3 phosphatase activity and endocytic membrane homeostasis. J. Biol. Chem. 2009, 284:35794-35806.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 35794-35806
-
-
Ikonomov, O.C.1
Sbrissa, D.2
Fenner, H.3
Shisheva, A.4
-
10
-
-
84865127881
-
PIKfyve and its lipid products in health and in sickness
-
Shisheva A. PIKfyve and its lipid products in health and in sickness. Curr. Top. Microbiol. Immunol. 2012, 362:127-162.
-
(2012)
Curr. Top. Microbiol. Immunol.
, vol.362
, pp. 127-162
-
-
Shisheva, A.1
-
11
-
-
8644280423
-
A mammalian ortholog of Saccharomyces cerevisiae Vac14 that associates with and up-regulates PIKfyve phosphoinositide 5-kinase activity
-
Sbrissa D., Ikonomov O.C., Strakova J., Dondapati R., Mlak K., Deeb R., Silver R., Shisheva A. A mammalian ortholog of Saccharomyces cerevisiae Vac14 that associates with and up-regulates PIKfyve phosphoinositide 5-kinase activity. Mol. Cell. Biol. 2004, 24:10437-10447.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 10437-10447
-
-
Sbrissa, D.1
Ikonomov, O.C.2
Strakova, J.3
Dondapati, R.4
Mlak, K.5
Deeb, R.6
Silver, R.7
Shisheva, A.8
-
12
-
-
56249092073
-
ArPIKfyve homomeric and heteromeric interactions scaffold PIKfyve and Sac3 in a complex to promote PIKfyve activity and functionality
-
Sbrissa D., Ikonomov O.C., Fenner H., Shisheva A. ArPIKfyve homomeric and heteromeric interactions scaffold PIKfyve and Sac3 in a complex to promote PIKfyve activity and functionality. J. Mol. Biol. 2008, 384:766-779.
-
(2008)
J. Mol. Biol.
, vol.384
, pp. 766-779
-
-
Sbrissa, D.1
Ikonomov, O.C.2
Fenner, H.3
Shisheva, A.4
-
13
-
-
77956243411
-
ArPIKfyve regulates Sac3 protein abundance and turnover: disruption of the mechanism by Sac3I41T mutation causing Charcot-Marie-Tooth 4J disorder
-
Ikonomov O.C., Sbrissa D., Fligger J., Delvecchio K., Shisheva A. ArPIKfyve regulates Sac3 protein abundance and turnover: disruption of the mechanism by Sac3I41T mutation causing Charcot-Marie-Tooth 4J disorder. J. Biol. Chem. 2010, 285:26760-26764.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 26760-26764
-
-
Ikonomov, O.C.1
Sbrissa, D.2
Fligger, J.3
Delvecchio, K.4
Shisheva, A.5
-
14
-
-
34548221502
-
Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex
-
Sbrissa D., Ikonomov O.C., Fu Z., Ijuin T., Gruenberg J., Takenawa T., Shisheva A. Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex. J. Biol. Chem. 2007, 282:23878-23891.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 23878-23891
-
-
Sbrissa, D.1
Ikonomov, O.C.2
Fu, Z.3
Ijuin, T.4
Gruenberg, J.5
Takenawa, T.6
Shisheva, A.7
-
15
-
-
35148886268
-
The phosphoinositide kinase PIKfyve mediates epidermal growth factor receptor trafficking to the nucleus
-
Kim J., Jahng W.J., Di Vizio D., Lee J.S., Jhaveri R., Rubin M.A., Shisheva A., Freeman M.R. The phosphoinositide kinase PIKfyve mediates epidermal growth factor receptor trafficking to the nucleus. Cancer Res. 2007, 67:9229-9237.
-
(2007)
Cancer Res.
, vol.67
, pp. 9229-9237
-
-
Kim, J.1
Jahng, W.J.2
Di Vizio, D.3
Lee, J.S.4
Jhaveri, R.5
Rubin, M.A.6
Shisheva, A.7
Freeman, M.R.8
-
16
-
-
80052744106
-
The NPM-ALK oncogene interacts, activates and uses PIKfyve to increase invasiveness
-
Dupuis-Coronas S., Lagarrigue F., Ramel D., Chicanne G., Saland E., Gaits-Iacovoni F., Payrastre B., Tronchere H. The NPM-ALK oncogene interacts, activates and uses PIKfyve to increase invasiveness. J. Biol. Chem. 2011, 286:32105-32114.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 32105-32114
-
-
Dupuis-Coronas, S.1
Lagarrigue, F.2
Ramel, D.3
Chicanne, G.4
Saland, E.5
Gaits-Iacovoni, F.6
Payrastre, B.7
Tronchere, H.8
-
17
-
-
84862195351
-
COLT-cancer: functional genetic screening resource for essential genes in human cancer cell lines
-
Koh J.L., Brown K.R., Sayad A., Kasimer D., Ketela T., Moffat J. COLT-cancer: functional genetic screening resource for essential genes in human cancer cell lines. Nucleic Acids Res. 2012, 40:D957-D963.
-
(2012)
Nucleic Acids Res.
, vol.40
-
-
Koh, J.L.1
Brown, K.R.2
Sayad, A.3
Kasimer, D.4
Ketela, T.5
Moffat, J.6
-
19
-
-
34250006277
-
ArPIKfyve-PIKfyve interaction and role in insulin-regulated GLUT4 translocation and glucose transport in 3T3-L1 adipocytes
-
Ikonomov O.C., Sbrissa D., Dondapati R., Shisheva A. ArPIKfyve-PIKfyve interaction and role in insulin-regulated GLUT4 translocation and glucose transport in 3T3-L1 adipocytes. Exp. Cell Res. 2007, 313:2404-2416.
-
(2007)
Exp. Cell Res.
, vol.313
, pp. 2404-2416
-
-
Ikonomov, O.C.1
Sbrissa, D.2
Dondapati, R.3
Shisheva, A.4
-
20
-
-
79953854419
-
The phosphoinositide kinase PIKfyve is vital in early embryonic development: preimplantation lethality of PIKfyve-/- embryos but normality of PIKfyve+/- mice
-
Ikonomov O.C., Sbrissa D., Delvecchio K., Xie Y., Jin J.P., Rappolee D., Shisheva A. The phosphoinositide kinase PIKfyve is vital in early embryonic development: preimplantation lethality of PIKfyve-/- embryos but normality of PIKfyve+/- mice. J. Biol. Chem. 2011, 286:13404-13413.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 13404-13413
-
-
Ikonomov, O.C.1
Sbrissa, D.2
Delvecchio, K.3
Xie, Y.4
Jin, J.P.5
Rappolee, D.6
Shisheva, A.7
-
21
-
-
14844328642
-
Acquisition of unprecedented phosphatidylinositol 3,5-bisphosphate rise in hyperosmotically stressed 3T3-L1 adipocytes, mediated by ArPIKfyve-PIKfyve pathway
-
Sbrissa D., Shisheva A. Acquisition of unprecedented phosphatidylinositol 3,5-bisphosphate rise in hyperosmotically stressed 3T3-L1 adipocytes, mediated by ArPIKfyve-PIKfyve pathway. J. Biol. Chem. 2005, 280:7883-7889.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 7883-7889
-
-
Sbrissa, D.1
Shisheva, A.2
-
22
-
-
0033618375
-
PIKfyve, a mammalian ortholog of yeast Fab1p lipid kinase, synthesizes 5-phosphoinositides. Effect of insulin
-
Sbrissa D., Ikonomov O.C., Shisheva A. PIKfyve, a mammalian ortholog of yeast Fab1p lipid kinase, synthesizes 5-phosphoinositides. Effect of insulin. J. Biol. Chem. 1999, 274:21589-21597.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 21589-21597
-
-
Sbrissa, D.1
Ikonomov, O.C.2
Shisheva, A.3
-
23
-
-
41449111117
-
PIKfyve negatively regulates exocytosis in neurosecretory cells
-
Osborne S.L., Wen P.J., Boucheron C., Nguyen H.N., Hayakawa M., Kaizawa H., Parker P.J., Vitale N., Meunier F.A. PIKfyve negatively regulates exocytosis in neurosecretory cells. J. Biol. Chem. 2008, 283:2804-2813.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 2804-2813
-
-
Osborne, S.L.1
Wen, P.J.2
Boucheron, C.3
Nguyen, H.N.4
Hayakawa, M.5
Kaizawa, H.6
Parker, P.J.7
Vitale, N.8
Meunier, F.A.9
-
24
-
-
0004402374
-
PIKfyve and acute insulin actions.
-
From Cultured Cells to Animal Models, Taylor and Francis,
-
A. Shisheva, C. DeMarco, O. Ikonomov, D. Sbrissa, PIKfyve and acute insulin actions. in: A. Sima, E. Shafrir, (Eds.) Insulin Signaling: From Cultured Cells to Animal Models, Taylor and Francis, 2002, pp. 189-206.
-
(2002)
A. Sima, E. Shafrir, (Eds.) Insulin Signaling
, pp. 189-206
-
-
Shisheva, A.1
DeMarco, C.2
Ikonomov, O.3
Sbrissa, D.4
-
25
-
-
79959850951
-
Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J
-
Lenk G.M., Ferguson C.J., Chow C.Y., Jin N., Jones J.M., Grant A.E., Zolov S.N., Winters J.J., Giger R.J., Dowling J.J., Weisman L.S., Meisler M.H. Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J. PLoS Genet. 2011, 7:e1002104.
-
(2011)
PLoS Genet.
, vol.7
-
-
Lenk, G.M.1
Ferguson, C.J.2
Chow, C.Y.3
Jin, N.4
Jones, J.M.5
Grant, A.E.6
Zolov, S.N.7
Winters, J.J.8
Giger, R.J.9
Dowling, J.J.10
Weisman, L.S.11
Meisler, M.H.12
-
26
-
-
84885180114
-
PtdIns5P: News and views of its appearance, disappearance and deeds
-
Shisheva A. PtdIns5P: News and views of its appearance, disappearance and deeds. Arch. Biochem. Biophys. 2013, 538:171-180.
-
(2013)
Arch. Biochem. Biophys.
, vol.538
, pp. 171-180
-
-
Shisheva, A.1
|