Ultrasmall metal nanoclusters for bio-related applications

Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

Volumn 5, Issue 6, 2013, Pages 569-581

  Tan, Xiaohong ^a   Jin, Rongchao ^a  

^a CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL APPLICATIONS; BIOLOGICAL IMAGING; BIOMEDICAL RESEARCH; METAL NANOCLUSTERS; NANOSCIENCE AND NANOTECHNOLOGIES; OTHER PROPERTIES; PHOTO-STABILITY; SUB NANOMETERS;

BIOCOMPATIBILITY; NANOCLUSTERS; NANOSCIENCE;

METALS;

LEAD; MERCURY; METAL NANOPARTICLE; NUCLEIC ACID; PROTEIN; SILVER;

ARTICLE; BIOCOMPATIBILITY; BIOSENSOR; HUMAN; MEDICAL RESEARCH; MOLECULAR IMAGING; MOLECULAR STABILITY; NONHUMAN; PARTICLE SIZE; PHOTOCHEMICAL QUENCHING; PHOTOLUMINESCENCE; PRIORITY JOURNAL;

ANIMALS; BIOMEDICAL RESEARCH; BIOSENSING TECHNIQUES; BIOTECHNOLOGY; CELL LINE; HUMANS; METAL NANOPARTICLES; MICE; NANOTECHNOLOGY; OPTICAL IMAGING; PARTICLE SIZE;

EID: 84885844232     PISSN: 19395116     EISSN: 19390041     Source Type: Journal    
DOI: 10.1002/wnan.1237     Document Type: Article

References (89)

1. Jin R. Quantum sized, thiolate-protected gold nanoclusters. Nanoscale 2010, 2:343-362.
2. Zheng J, Nicovich PR, Dickson RM. Highly fluorescent noble-metal quantum dots. Annu Rev Phys Chem 2007, 58:409-431.
3. Zheng J, Zhang C, Dickson RM. Highly fluorescent, water-soluble, size-tunable gold quantum dots. Phys Rev Lett 2004, 93:077402.
4. Wilcoxon JP, Martin JE, Parsapour F, Wiedenman B, Kelley DF. Photoluminescence from nanosize gold clusters. J Chem Phys 1998, 108:9137-9143.
5. Shan J, Tenhu H. Recent advances in polymer protected gold nanoparticles: synthesis, properties and applications. Chem Commun 2007, 44:4580-4598.
6. Sardar R, Funston AM, Mulvaney P, Murray RW. Gold nanoparticles: past, present, and future. Langmuir 2009, 25:13840-13851.
7. Grzelczak M, Perez-Juste J, Mulvaney P, Liz-Marzan LM. Shape control in gold nanoparticle synthesis. Chem Soc Rev 2008, 37:1783-1791.
8. Qian H, Zhu M, Wu Z, Jin R. Quantum sized gold nanoclusters with atomic precision. Acc Chem Res 2012, 45:1470-1479.
9. Shang L, Dörlich RM, Trouillet V, Bruns M, Nienhaus GU. Ultrasmall fluorescent silver nanoclusters: protein adsorption and its effects on cellular responses. Nano Res 2012, 5:531-542.
10. Shang L, Dong S, Nienhaus GU. Ultra-small fluorescent metal nanoclusters: synthesis and biological applications. Nano Today 2011, 6:401-418.
11. Lu Y, Wei W, Chen W. Copper nanoclusters: synthesis, characterization and properties. Chin Sci Bull 2012, 57:41-47.
12. Tracy JB, Kalyuzhny G, Crowe MC, Balasubramanian R, Choi J-P, Murray RW. Poly(ethylene glycol) ligands for high-resolution nanoparticle mass spectrometry. J Am Chem Soc 2007, 129:6706-6707.
13. Cathcart N, Mistry P, Makra C, Pietrobon B, Coombs N, Jelokhani-Niaraki M, Kitaev V. Chiral thiol-stabilized silver nanoclusters with well-resolved optical transitions synthesized by a facile etching procedure in aqueous solutions. Langmuir 2009, 25:5840-5846.
14. Xu H, Suslick KS. Water-soluble fluorescent silver nanoclusters. Adv Mater 2010, 22:1078-1082.
15. Aiken Iii JD, Finke RG. A review of modern transition-metal nanoclusters: their synthesis, characterization, and applications in catalysis. J Mol Catal A Chem 1999, 145(1-2):1-44.
16. Wilcoxon JP, Abrams BL. Synthesis, structure and properties of metal nanoclusters. Chem Soc Rev 2006, 35:1162-1194.
17. Diez I, Ras RHA. Fluorescent silver nanoclusters. Nanoscale 2011, 3:1963-1970.
18. Demchenko AP, Muhammed MAH, Pradeep T. Luminescent quantum clusters of gold as bio-labels. In: Advanced Fluorescence Reporters in Chemistry and Biology II, vol. 9. Berlin, Heidelberg: Springer; 2010, 333-353.
19. Wen F, Dong Y, Feng L, Wang S, Zhang S, Zhang X. Horseradish peroxidase functionalized fluorescent gold nanoclusters for hydrogen peroxide sensing. Anal Chem 2011, 83:1193-1196.
20. Chen WY, Lin JY, Chen WJ, Luo L, Wei-Guang Diau E, Chen YC. Functional gold nanoclusters as antimicrobial agents for antibiotic-resistant bacteria. Nanomedicine (Lond) 2010, 5:755-764.
21. He S, Li D, Zhu C, Song S, Wang L, Long Y, Fan C. Design of a gold nanoprobe for rapid and portable mercury detection with the naked eye. Chem Commun 2008, 40:4885-4887.
22. Huang C-C, Chang H-T. Parameters for selective colorimetric sensing of mercury(ii) in aqueous solutions using mercaptopropionic acid-modified gold nanoparticles. Chem Commun 2007, 12:1215-1217.
23. 2+) in aqueous media using DNA-functionalized gold nanoparticles. Angew Chem Int Ed 2007, 119:4171-4174.
24. 2+ ions by oligonucleotide-gold-nanoparticle hybrids and DNA-based machines. Angew Chem Int Ed 2008, 47:3927-3931.
25. Guo C, Irudayaraj J. Fluorescent Ag clusters via a protein-directed approach as a Hg(II) ion sensor. Anal Chem 2011, 83:2883-2889.
26. 2+ ion. Chem Commun 2009, 23:3395-3397.
27. Adhikari B, Banerjee A. Facile synthesis of water-soluble fluorescent silver nanoclusters and HgII sensing. Chem Mater 2010, 22:4364-4371.
28. + based on the fluorescence quenching of lysozyme type VI-stabilized gold nanoclusters. Anal Chem 2010, 82:9194-9200.
29. 2+ ion. Anal Chem 2011, 83:9676-9680.
30. Xavier PL, Chaudhari K, Verma PK, Pal SK, Pradeep T. Luminescent quantum clusters of gold in transferrin family protein, lactoferrin exhibiting FRET. Nanoscale 2010, 2:2769-2776.
31. Ishii A, Seno H, Watanabe-Suzuki K, Suzuki O, Kumazawa T. Determination of cyanide in whole blood by capillary gas chromatography with cryogenic oven trapping. Anal Chem 1998, 70:4873-4876.
32. Tomasulo M, Sortino S, White AJP, Raymo FM. Chromogenic oxazines for cyanide detection. J Org Chem 2005, 71:744-753.
33. Wang X-B, Wang Y-L, Yang J, Xing X-P, Li J, Wang L-S. Evidence of significant covalent bonding in Au(CN)(2)(-) J Am Chem Soc 2009, 131:16368-16370.
34. Liu Y, Ai K, Cheng X, Huo L, Lu L. Gold-nanocluster-based fluorescent sensors for highly sensitive and selective detection of cyanide in water. Adv Funct Mater 2010, 20:951-956.
35. Habeeb Muhammed MA, Verma PK, Pal SK, Retnakumari A, Koyakutty M, Nair S, Pradeep T. Luminescent quantum clusters of gold in bulk by albumin-induced core etching of nanoparticles: metal ion sensing, metal-enhanced luminescence, and biolabeling. Eur J Chem A 2010, 16:10103-10112.
36. Kawasaki H, Hamaguchi K, Osaka I, Arakawa R. ph-Dependent synthesis of pepsin-mediated gold nanoclusters with blue green and red fluorescent emission. Adv Func Mater 2011, 21:3508-3515.
37. Pu K-Y, Luo Z, Li K, Xie J, Liu B. Energy transfer between conjugated-oligoelectrolyte-substituted POSS and gold nanocluster for multicolor intracellular detection of mercury ion. J Phys Chem C 2011, 115:13069-13075.
38. Triulzi RC, Micic M, Giordani S, Serry M, Chiou W-A, Leblanc RM. Immunoasssay based on the antibody-conjugated PAMAM-dendrimer-gold quantum dot complex. Chem Commun 2006, 48:5068-5070.
39. Shiang Y-C, Lin C-A, Huang C-C, Chang H-T. Protein A-conjugated luminescent gold nanodots as a label-free assay for immunoglobulin G in plasma. Analyst 2011, 136:1177-1182.
40. Huang C-C, Chiang C-K, Lin Z-H, Lee K-H, Chang H-T. Bioconjugated gold nanodots and nanoparticles for protein assays based on photoluminescence quenching. Anal Chem 2008, 80:1497-1504.
41. Huang C-C, Chen C-T, Shiang Y-C, Lin Z-H, Chang H-T. Synthesis of fluorescent carbohydrate-protected au nanodots for detection of concanavalin A and Escherichia coli. Anal Chem 2009, 81:875-882.
42. Sharma J, Yeh H-C, Yoo H, Werner JH, Martinez JS. Silver nanocluster aptamers: in situ generation of intrinsically fluorescent recognition ligands for protein detection. Chem Commun 2010, 47:2294-2296.
43. Lan G-Y, Chen W-Y, Chang H-T. Characterization and application to the detection of single-stranded DNA binding protein of fluorescent DNA-templated copper/silver nanoclusters. Analyst 2011, 136:3623-3628.
44. Zhang J, Sajid M, Na N, Huang L, He D, Ouyang J. The application of Au nanoclusters in the fluorescence imaging of human serum proteins after native PAGE: enhancing detection by low-temperature plasma treatment. Biosens Bioelectron 2012, 35:313-318.
45. Tran TH, Park S, Lee H, Park S, Kim B, Kim OH, Oh BC, Lee D, Lee H. Ultrasmall gold nanoparticles for highly specific isolation/enrichment of N-linked glycosylated peptides. Analyst 2012, 137:991-998.
46. Wang M, Mei Q, Zhang K, Zhang Z. Protein-gold nanoclusters for identification of amino acids by metal ions modulated ratiometric fluorescence. Analyst 2012, 137:1618-1623.
47. Hussain AMP, Sarangi SN, Kesarwani JA, Sahu SN. Au-nanocluster emission based glucose sensing. Biosens Bioelectron 2011, 29:60-65.
48. Lan G-Y, Chen W-Y, Chang H-T. One-pot synthesis of fluorescent oligonucleotide Ag nanoclusters for specific and sensitive detection of DNA. Biosens Bioelectron 2011, 26:2431-2435.
49. Yang SW, Vosch T. Rapid detection of MicroRNA by a silver nanocluster DNA probe. Anal Chem 2011, 83:6935-6939.
50. Yeh H-C, Sharma J, Han JJ, Martinez JS, Werner JH. A DNA-silver nanocluster probe that fluoresces upon hybridization. Nano Lett 2010, 10:3106-3110.
51. Giepmans BNG, Adams SR, Ellisman MH, Tsien RY. The fluorescent toolbox for assessing protein location and function. Science 2006, 312:217-224.
52. Resch-Genger U, Grabolle M, Cavaliere-Jaricot S, Nitschke R, Nann T. Quantum dots versus organic dyes as fluorescent labels. Nat Methods 2008, 5:763-775.
53. Baker M. Nanotechnology imaging probes: smaller and more stable. Nat Methods 2010, 7:957-962.
54. Polavarapu L, Manna M, Xu QH. Biocompatible glutathione capped gold clusters as one- and two-photon excitation fluorescence contrast agents for live cells imaging. Nanoscale 2011, 3:429-434.
55. Wu X, He X, Wang K, Xie C, Zhou B, Qing Z. Ultrasmall near-infrared gold nanoclusters for tumor fluorescence imaging in vivo. Nanoscale 2010, 2:2244-2249.
56. Lin C-AJ, Yang T-Y, Lee C-H, Huang SH, Sperling RA, Zanella M, Li JK, Shen J-L, Wang H-H, Yeh H-I, et al. Synthesis, characterization, and bioconjugation of fluorescent gold nanoclusters toward biological labeling applications. ACS Nano 2009, 3:395-401.
57. Koo H, Huh MS, Ryu JH, Lee D-E, Sun I-C, Choi K, Kim K, Kwon IC. Nanoprobes for biomedical imaging in living systems. Nano Today 2011, 6:204-220.
58. Michalet X, Pinaud FF, Bentolila LA, Tsay JM, Doose S, Li JJ, Sundaresan G, Wu AM, Gambhir SS, Weiss S. Quantum dots for live cells, in vivo imaging, and diagnostics. Science 2005, 307:538-544.
59. Soo Choi H, Liu W, Misra P, Tanaka E, Zimmer JP, Itty Ipe B, Bawendi MG, Frangioni JV. Renal clearance of quantum dots. Nat Biotechnol 2007, 25:1165-1170.
60. Abad JM, Sendroiu IE, Gass M, Bleloch A, Mills AJ, Schiffrin DJ. Synthesis of ω-hydroxy hexathiolate-protected subnanometric gold clusters. J Am Chem Soc 2007, 129:12932-12933.
61. Yu J, Patel SA, Dickson RM. In vitro and intracellular production of peptide-encapsulated fluorescent silver nanoclusters. Angew Chem Int Ed 2007, 46:2028-2030.
62. Yu J, Choi S, Richards CI, Antoku Y, Dickson RM. Live cell surface labeling with fluorescent Ag nanocluster conjugates. Photochem Photobiol 2008, 84:1435-1439.
63. Liu C-L, Wu H-T, Hsiao Y-H, Lai C-W, Shih C-W, Peng Y-K, Tang K-C, Chang H-W, Chien Y-C, Hsiao J-K, et al. Insulin-directed synthesis of fluorescent gold nanoclusters: preservation of insulin bioactivity and versatility in cell imaging. Angew Chem Int Ed 2011, 50:7056-7060.
64. Retnakumari A, Setua S, Menon D, Ravindran P, Muhammed H, Pradeep T, Nair S, Koyakutty M. Molecular-receptor-specific, non-toxic, near-infrared-emitting Au cluster-protein nanoconjugates for targeted cancer imaging. Nanotechnology 2010, 21:055103.
65. Huang X, Luo Y, Li Z, Li B, Zhang H, Li L, Majeed I, Zou P, Tan B. Biolabeling hematopoietic system cells using near-infrared fluorescent gold nanoclusters. J Phys Chem C 2011, 115:16753-16763.
66. Le Guevel X, Daum N, Schneider M. Synthesis and characterization of human transferrin-stabilized gold nanoclusters. Nanotechnology 2011, 22:275103.
67. Diaspro A, Robello M. Two-photon excitation of fluorescence for three-dimensional optical imaging of biological structures. J Photochem Photobiol B Biol 2000, 55:1-8.
68. Liu C-L, Ho M-L, Chen Y-C, Hsieh C-C, Lin Y-C, Wang Y-H, Yang M-J, Duan H-S, Chen B-S, Lee J-F, et al. Thiol-functionalized gold nanodots: two-photon absorption property and imaging in vitro. J Phys Chem C 2009, 113:21082-21089.
69. Shang L, Dorlich RM, Brandholt S, Schneider R, Trouillet V, Bruns M, Gerthsen D, Nienhaus GU. Facile preparation of water-soluble fluorescent gold nanoclusters for cellular imaging applications. Nanoscale 2011, 3:2009-2014.
70. Lin S-Y, Chen N-T, Sum S-P, Lo L-W, Yang C-S. Ligand exchanged photoluminescent gold quantum dots functionalized with leading peptides for nuclear targeting and intracellular imaging. Chem Commun 2008, 39:4762-4764.
71. Wang Y, Chen J, Irudayaraj J. Nuclear targeting dynamics of gold nanoclusters for enhanced therapy of HER2+ breast cancer. ACS Nano 2011, 5:9718-9725.
72. Makarava N, Parfenov A, Baskakov IV. Water-soluble hybrid nanoclusters with extra bright and photostable emissions: a new tool for biological imaging. Biophys J 2005, 89:572-580.
73. Choi S, Yu J, Patel SA, Tzeng YL, Dickson RM. Tailoring silver nanodots for intracellular staining. Photochem Photobiol Sci 2010, 10:109-15.
74. Sun Z, Wang Y, Wei Y, Liu R, Zhu H, Cui Y, Zhao Y, Gao X. Ag cluster-aptamer hybrid: specifically marking the nucleus of live cells. Chem Commun 2011, 47:11960-11962.
75. Sousa AA, Morgan JT, Brown PH, Adams A, Jayasekara MP, Zhang G, Ackerson CJ, Kruhlak MJ, Leapman RD. Synthesis, characterization, and direct intracellular imaging of ultrasmall and uniform glutathione-coated gold nanoparticles. Small 2012, 8:2277-2286.
76. Yang L, Shang L, Nienhaus GU. Mechanistic aspects of fluorescent gold nanocluster internalization by live HeLa cells. Nanoscale 2013, 5:1537-1543.
77. Rao J, Dragulescu-Andrasi A, Yao H. Fluorescence imaging in vivo: recent advances. Curr Opin Biotechnol 2007, 18:17-25.
78. Wang C, Gao X, Su X. In vitro and in vivo imaging with quantum dots. Anal Bioanal Chem 2010, 397:1397-1415.
79. Sun C, Yang H, Yuan Y, Tian X, Wang L, Guo Y, Xu L, Lei J, Gao N, Anderson GJ, et al. Controlling assembly of paired gold clusters within apoferritin nanoreactor for in vivo kidney targeting and biomedical imaging. J Am Chem Soc 2011, 133:8617-8624.
80. Zhou C, Long M, Qin Y, Sun X, Zheng J. Luminescent gold nanoparticles with efficient renal clearance. Angew Chem Int Ed 2011, 50:3168-3172.
81. Huang K, Ma H, Liu J, Huo S, Kumar A, Wei T, Zhang X, Jin S, Gan Y, Wang PC, et al. Size-dependent localization and penetration of ultrasmall gold nanoparticles in cancer cells, multicellular spheroids, and tumors in vivo. ACS Nano 2012, 6:4483-4493.
82. Zhang A, Tu Y, Qin S, Li Y, Zhou J, Chen N, Lu Q, Zhang B. Gold nanoclusters as contrast agents for fluorescent and X-ray dual-modality imaging. J Colloid Interface Sci 2012, 372:239-244.
83. Zhang X, Chibli H, Mielke R, Nadeau J. Ultrasmall gold-doxorubicin conjugates rapidly kill apoptosis-resistant cancer cells. Bioconjug Chem 2011, 22:235-243.
84. Kumar SA, Peter YA, Nadeau JL. Facile biosynthesis, separation and conjugation of gold nanoparticles to doxorubicin. Nanotechnology 2008, 19:495101.
85. Zhang X, Chibli H, Kong D, Nadeau J. Comparative cytotoxicity of gold-doxorubicin and InP-doxorubicin conjugates. Nanotechnology 2012, 23:275103.
86. Chen T, Xu S, Zhao T, Zhu L, Wei D, Li Y, Zhang H, Zhao C. Gold nanocluster-conjugated amphiphilic block copolymer for tumor-targeted drug delivery. ACS Appl Mater Interfaces 2012, 4:5766-5774.
87. Li G, Qian H, Jin R. Gold nanocluster-catalyzed selective oxidation of sulfide to sulfoxide. Nanoscale 2012, 4:6714-6717.
88. Zhang Y, Cui X, Shi F, Deng Y. Nano-gold catalysis in fine chemical synthesis. Chem Rev 2012, 112:2467-2505.
89. 2 toward methanol, alcohols and hydrocarbons on promoted copper-rare earth oxides catalysts. Catal Today 1997, 36:15-24.