Enhanced SCAP Glycosylation by Inflammation Induces Macrophage Foam Cell Formation

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Zhou, Chao ^a,b,c   Lei, Han ^a,b   Chen, Yaxi ^a   Liu, Qing ^b   Li, Lung Chih ^c,d   Moorhead, John F ^c   Varghese, Zac ^c   Ruan, Xiong Z ^a,c  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LOW DENSITY LIPOPROTEIN RECEPTOR; MANNOSIDASE; MANNOSIDASE II; REGULATOR PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; STEROL REGULATORY ELEMENT BINDING PROTEIN CLEAVAGE ACTIVATING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL TRANSFORMATION; CHOLESTEROL METABOLISM; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FOAM CELL; GOLGI COMPLEX; HUMAN; HUMAN CELL; INFLAMMATION; LIPID STORAGE; MACROPHAGE; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN TRANSPORT; QUANTITATIVE ANALYSIS; QUANTITATIVE ASSAY; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

CELL DIFFERENTIATION; CELL LINE; CHOLESTEROL, LDL; ENDOPLASMIC RETICULUM; ENZYME INHIBITORS; FEEDBACK, PHYSIOLOGICAL; FOAM CELLS; GENE EXPRESSION REGULATION; GLYCOSYLATION; GOLGI APPARATUS; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; INFLAMMATION; INTERLEUKIN-6; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MANNOSIDASES; MEMBRANE PROTEINS; PROTEIN TRANSPORT; PROTEOLYSIS; RECEPTORS, LDL; SIGNAL TRANSDUCTION; STEROL REGULATORY ELEMENT BINDING PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84885813725     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0075650     Document Type: Article

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