Cross-talk between TLR4-MyD88-NF-κB and SCAP-SREBP2 pathways mediates macrophage foam cell formation

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 304, Issue 6, 2013, Pages

  Li, Lung Chih ^a,b   Varghese, Zac ^a   Moorhead, John F ^a   Lee, Chien Te ^b   Chen, Jin Bor ^b   Ruan, Xiong Z ^a,c  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^c CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

3 hydroxy 3 methylglutaryl coenzyme A reductase; Low density lipoprotein receptor; Myeloid differentiation factor 88; Nuclear factor B; Sterol regulatory element binding protein; Sterol regulatory element binding protein cleavage activating protein; Toll like receptor

Indexed keywords

4 (2 AMINOETHYLAMINO) 1,8 DIMETHYLIMIDAZO[1,2 A]QUINOXALINE; CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; PHORBOL 13 ACETATE 12 MYRISTATE; SMALL INTERFERING RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TOLL LIKE RECEPTOR 4;

ARTICLE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FOAM CELL; GOLGI COMPLEX; HUMAN; HUMAN CELL; MACROPHAGE; MACROPHAGE ACTIVATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; WESTERN BLOTTING;

CELL LINE; CHOLESTEROL; ENDOPLASMIC RETICULUM; FOAM CELLS; GENE EXPRESSION REGULATION; GOLGI APPARATUS; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; I-KAPPA B KINASE; IMIDAZOLES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPOPOLYSACCHARIDES; LIPOPROTEINS, LDL; MEMBRANE PROTEINS; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PROTEIN TRANSPORT; QUINOXALINES; RECEPTORS, LDL; RNA, SMALL INTERFERING; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TOLL-LIKE RECEPTOR 4;

EID: 84878566246     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00096.2012     Document Type: Article

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