Erythropoiesis

Postgraduate Haematology: Sixth Edition

Volumn , Issue , 2010, Pages 12-25

  Higgs, Douglas R ^a   Wood, William G ^a  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

Apoptosis during normal erythropoiesis; Erythroid differentiation and maturation within adult bone marrow in vivo; Erythropoiesis; Erythropoiesis process, all steps of haemopoiesis haemopoietic stem cell (HSC) specification from mesoderm; Erythropoiesis, disturbed to a greater or lesser extent in all multisystem diseases; HSCs differentiation, forming erythroid progenitors; Key transcription factors, controlling erythroid progenitors lineage specification and erythroid differentiation; Primitive haemopoiesis in humans appearing in blood islands of extraembryonic yolk sac, on day 21 of gestation; Sensing hypoxia, tissue hypoxia physiological responses and Epo EpoR pathway activation; Terminal maturation of erythroid cells

Indexed keywords

EID: 84885803191     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781444323160.ch2     Document Type: Chapter

References (23)

1. Cross MA, Enver T (1997) The lineage commitment of haemopoietic progenitor cells. Current Opinion in Genetics and Development 7: 609-13.
2. Dzierzak E, Speck NA (2008) Of lineage and legacy: the development of mammalian haematopoietic stem cells. Nature Immunology 9: 129-36.
3. Joshi C, Enver T (2003) Molecular complexities of stem cells. Current Opinion in Hematology 10: 220-8.
4. Murre C (2007) Defining the pathways of early adult hematopoiesis. Cell Stem Cell 1: 357-8.
5. Orkin SH, Zon LI (2008) Hematopoiesis: an evolving paradigm for stem cell biology. Cell 132: 631-44.
6. Palis J (2008) Ontogeny of erythropoiesis. Current Opinions in Haematology 15: 155-61.
7. Tavian M, Hallais M-F, Péault B (1999) Emergence of intraembryonic haematopoietic precursors in the pre -liver human embryo. Development 126: 793-803.
8. Wickramasinghe SN (1975) Erythropoiesis. In: Human Bone Marrow (SN Wickramasinghe, ed.), pp. 162-232. Blackwell Scientific Publications, Oxford.
9. Beguin Y (2003) Soluble transferrin receptor for the evaluation of erythropoiesis and iron status. Clinica Chimica Acta 329: 9-22.
10. Bunn HF (2007) New agents that stimulate erythropoiesis. Blood 109: 868-73.
11. De Maria R, Zeuner A, Eramo A et al. (1999) Negative regulation of erythropoiesis by caspase -mediated cleavage of GATA -1. Nature 401: 489-93.
12. Panzenbock B, Bartunek P, Mapara MY et al. (1998) Growth and differentiation of human stem cell factor/erythropoietin -dependent erythroid progenitor cells in vitro. Blood 92: 3658-68.
13. Schofield CJ, Ratcliffe PJ (2004) Oxygen sensing by HIF hydroxylases. Nature Reviews. Molecular Cell Biology 5: 343-54.
14. Bungert J, Engel JD (1996) The role of transcription factors in erythroid development. Annals of Medicine 28: 47-55.
15. Cantor AB, Orkin SH (2002) Transcriptional regulation of erythropoiesis: an affair involving multiple partners. Oncogene 21: 3368-76.
16. Gubin AN, Njoroge JM, Bouffard GG et al. (1999) Gene expression in proliferating human erythroid cells. Genomics 59: 168-77.
17. Shivdasani RA, Orkin SH (1996) The transcriptional control of hematopoiesis. Blood 87: 4025-39.
18. Sieweke MH, Graf T (1998) A transcriptional factor party during blood cell differentiation. Current Opinion in Genetics and Development 8: 545-51.
19. Beguin Y (2003) Soluble transferrin receptor for the evaluation of erythropoiesis and iron status. Clinica Chimica Acta 329: 9-22.
20. Eschbach JW (2000) Current concepts of anaemia management in chronic renal failure: impact of NKF -DOQI. Seminars in Nephrology 20: 320-9.
21. Muirhead N, Bargman JA, Burgess E et al. (1995) Evidence -based recommendations for the clinical use of recombinant human erythropoietin. American Journal of Kidney Disease 26: S1-S24.
22. Samol J, Littlewood TJ (2003) The efficacy of rHuEPO in cancer -related anaemia. British Journal of Haematology 121: 3-11.
23. Unger FE, Thompson AM, Blank MJ et al. (2010) Erythropoiesissimulating agents-time for a reevaluation. The New England Journal of Medicine 362: 189-192.