An Exposure to the Oxidized DNA Enhances Both Instability of Genome and Survival in Cancer Cells

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Kostyuk, Svetlana V ^a   Konkova, Marina S ^a   Ershova, Elizaveta S ^a,b   Alekseeva, Anna J ^a   Smirnova, Tatiana D ^a   Stukalov, Sergey V ^a   Kozhina, Ekaterina A ^a   Shilova, Nadezda V ^a   Zolotukhina, Tatiana V ^a   Markova, Zhanna G ^a   Izhevskaya, Vera L ^a   Baranova, Ancha ^a,c   Veiko, Natalia N ^a  

^a RESEARCH CENTRE FOR MEDICAL GENETICS   (Russian Federation)

^b INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

^c GEORGE MASON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYGUANINE; CELL DNA; DOUBLE STRANDED DNA; GENOMIC DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OXIDIZED EXTRACELLULAR DNA; REACTIVE OXYGEN METABOLITE; SINGLE STRANDED DNA; STAT3 PROTEIN; TOLL LIKE RECEPTOR 9; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

AIM2 GENE; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL STRESS; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DETERMINATION; DNA FRAGMENTATION; DNA ISOLATION; DOUBLE STRANDED DNA BREAK; DOWN REGULATION; DRUG EXPOSURE; FLUORESCENCE ACTIVATED CELL SORTING; GENE; GENE EXPRESSION; GENE FUNCTION; GENE LOCATION; GENETIC MARKER; GENOME ANALYSIS; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; NFKAPPB GENE; NRF2 GENE; OXIDATIVE STRESS; RECOMBINANT DNA TECHNOLOGY; SINGLE STRANDED DNA BREAK; STAT3 GENE; TLR9 GENE; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; UPREGULATION;

BIOLOGICAL TRANSPORT; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL SURVIVAL; DNA BREAKS; DNA DAMAGE; DNA, CIRCULAR; GENOMIC INSTABILITY; HUMANS; INTRACELLULAR SPACE; MCF-7 CELLS; NEOPLASMS; NF-E2-RELATED FACTOR 2; NF-KAPPA B; NUCLEAR PROTEINS; OXIDATION-REDUCTION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; STAT3 TRANSCRIPTION FACTOR; TOLL-LIKE RECEPTOR 9;

EID: 84885763300     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0077469     Document Type: Article

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