Combination of LC3 shRNA Plasmid Transfection and Genistein Treatment Inhibited Autophagy and Increased Apoptosis in Malignant Neuroblastoma in Cell Culture and Animal Models

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Mohan, Nishant ^a   Chakrabarti, Mrinmay ^a   Banik, Naren L ^b   Ray, Swapan K ^a  

^a UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BECLIN 1; GENISTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN LIGHT CHAIN 3; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN P62; SHORT HAIRPIN RNA; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ANTIBIOTIC; EPIDERMAL GROWTH FACTOR RECEPTOR; LIGHT CHAIN 3, HUMAN; PROTEIN KINASE INHIBITOR; RAPAMYCIN; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL LINE; CELL ORGANELLE; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMR 32 CELL; MOUSE; NEUROBLASTOMA; NONHUMAN; SK N BE2 CELL; TUMOR CELL CULTURE; TUMOR XENOGRAFT; UPREGULATION; ANIMAL; CELL SURVIVAL; DRUG EFFECTS; GENETICS; METABOLISM; MITOCHONDRION; NUDE MOUSE; PATHOLOGY; PLASMID; RNA INTERFERENCE; TUMOR CELL LINE;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; APOPTOSIS; AUTOPHAGY; CELL LINE, TUMOR; CELL SURVIVAL; DOWN-REGULATION; GENISTEIN; HUMANS; MICE, NUDE; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; NEUROBLASTOMA; PLASMIDS; PROTEIN KINASE INHIBITORS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIROLIMUS; TRANSFECTION; UP-REGULATION;

EID: 84885763240     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0078958     Document Type: Article

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