메뉴 건너뛰기




Volumn 8, Issue 10, 2013, Pages

Characterization of Niemann-Pick Type C2 Protein Expression in Multiple Cancers Using a Novel NPC2 Monoclonal Antibody

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; EPIDERMAL GROWTH FACTOR RECEPTOR; EPITOPE; ESTROGEN RECEPTOR; IMMUNOGLOBULIN G2A; MONOCLONAL ANTIBODY; PROGESTERONE RECEPTOR; SHORT HAIRPIN RNA;

EID: 84885722777     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0077586     Document Type: Article
Times cited : (17)

References (26)
  • 1
    • 0029866407 scopus 로고    scopus 로고
    • Molecular cloning and characterization of HE1, a major secretory protein of the human epididymis
    • doi:10.1095/biolreprod54.4.847
    • Kirchhoff C, Osterhoff C, Young L, (1996) Molecular cloning and characterization of HE1, a major secretory protein of the human epididymis. Biol Reprod 54: 847-856. doi:10.1095/biolreprod54.4.847. PubMed: 8924505.
    • (1996) Biol Reprod , vol.54 , pp. 847-856
    • Kirchhoff, C.1    Osterhoff, C.2    Young, L.3
  • 2
    • 67649255316 scopus 로고    scopus 로고
    • Niemann-Pick C2 (NPC2) and intracellular cholesterol trafficking
    • doi:10.1016/j.bbalip.2009.02.001
    • Storch J, Xu Z, (2009) Niemann-Pick C2 (NPC2) and intracellular cholesterol trafficking. Biochim Biophys Acta 1791: 671-678. doi:10.1016/j.bbalip.2009.02.001. PubMed: 19232397.
    • (2009) Biochim Biophys Acta , vol.1791 , pp. 671-678
    • Storch, J.1    Xu, Z.2
  • 3
    • 4744376060 scopus 로고    scopus 로고
    • Lipid and cholesterol trafficking in NPC
    • doi:10.1016/j.bbalip.2004.08.009
    • Mukherjee S, Maxfield FR, (2004) Lipid and cholesterol trafficking in NPC. Biochim Biophys Acta 1685: 28-37. doi:10.1016/j.bbalip.2004.08.009. PubMed: 15465424.
    • (2004) Biochim Biophys Acta , vol.1685 , pp. 28-37
    • Mukherjee, S.1    Maxfield, F.R.2
  • 4
    • 0034704245 scopus 로고    scopus 로고
    • Identification of HE1 as the second gene of Niemann-Pick C disease
    • doi:10.1126/science.290.5500.2298
    • Naureckiene S, Sleat DE, Lackland H, Fensom A, Vanier MT, et al. (2000) Identification of HE1 as the second gene of Niemann-Pick C disease. Science 290: 2298-2301. doi:10.1126/science.290.5500.2298. PubMed: 11125141.
    • (2000) Science , vol.290 , pp. 2298-2301
    • Naureckiene, S.1    Sleat, D.E.2    Lackland, H.3    Fensom, A.4    Vanier, M.T.5
  • 5
    • 11144355005 scopus 로고    scopus 로고
    • Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport
    • doi:10.1073/pnas.0308456101
    • Sleat DE, Wiseman JA, El-Banna M, Price SM, Verot L, et al. (2004) Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport. Proc Natl Acad Sci U S A 101: 5886-5891. doi:10.1073/pnas.0308456101. PubMed: 15071184.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 5886-5891
    • Sleat, D.E.1    Wiseman, J.A.2    El-Banna, M.3    Price, S.M.4    Verot, L.5
  • 6
    • 4744350864 scopus 로고    scopus 로고
    • Structure and function of the NPC2 protein
    • doi:10.1016/j.bbalip.2004.08.007
    • Vanier MT, Millat G, (2004) Structure and function of the NPC2 protein. Biochim Biophys Acta 1685: 14-21. doi:10.1016/j.bbalip.2004.08.007. PubMed: 15465422.
    • (2004) Biochim Biophys Acta , vol.1685 , pp. 14-21
    • Vanier, M.T.1    Millat, G.2
  • 7
    • 84865626577 scopus 로고    scopus 로고
    • Glycine N-methyltransferase deficiency affects niemann-pick type c2 protein stability and regulates hepatic cholesterol homeostasis
    • Liao YJ, Chen TL, Lee TS, Wang HA, Wang CK, et al. (2012) Glycine N-methyltransferase deficiency affects niemann-pick type c2 protein stability and regulates hepatic cholesterol homeostasis. Mol Med 18: 412-422. PubMed: 22183894.
    • (2012) Mol Med , vol.18 , pp. 412-422
    • Liao, Y.J.1    Chen, T.L.2    Lee, T.S.3    Wang, H.A.4    Wang, C.K.5
  • 8
    • 79251551027 scopus 로고    scopus 로고
    • A novel role for Niemann-Pick disease type 2C protein in papillae formation
    • doi:10.1371/journal.pone.0015777
    • Sugawara M, Ohye H, Tomoda C, Kogai T, Kamata Y, et al. (2011) A novel role for Niemann-Pick disease type 2C protein in papillae formation. PLOS ONE 6: e15777. doi:10.1371/journal.pone.0015777. PubMed: 21253586.
    • (2011) PLOS ONE , vol.6
    • Sugawara, M.1    Ohye, H.2    Tomoda, C.3    Kogai, T.4    Kamata, Y.5
  • 9
    • 84860503878 scopus 로고    scopus 로고
    • Characterization of the Niemann-Pick C pathway in alveolar type II cells and lamellar bodies of the lung
    • doi:10.1152/ajplung.00383.2011
    • Roszell BR, Tao JQ, Yu KJ, Huang S, Bates SR, (2012) Characterization of the Niemann-Pick C pathway in alveolar type II cells and lamellar bodies of the lung. Am J Physiol Lung Cell Mol Physiol 302: L919-L932. doi:10.1152/ajplung.00383.2011. PubMed: 22367786.
    • (2012) Am J Physiol Lung Cell Mol Physiol , vol.302
    • Roszell, B.R.1    Tao, J.Q.2    Yu, K.J.3    Huang, S.4    Bates, S.R.5
  • 10
    • 78751541847 scopus 로고    scopus 로고
    • Somatic cell plasticity and Niemann-Pick type C2 protein: fibroblast activation
    • doi:10.1074/jbc.M110.135897
    • Csepeggi C, Jiang M, Kojima F, Crofford LJ, Frolov A, (2011) Somatic cell plasticity and Niemann-Pick type C2 protein: fibroblast activation. J Biol Chem 286: 2078-2087. doi:10.1074/jbc.M110.135897. PubMed: 21084287.
    • (2011) J Biol Chem , vol.286 , pp. 2078-2087
    • Csepeggi, C.1    Jiang, M.2    Kojima, F.3    Crofford, L.J.4    Frolov, A.5
  • 11
    • 0037261378 scopus 로고    scopus 로고
    • Characterization of reduced expression of glycine N-methyltransferase in cancerous hepatic tissues using two newly developed monoclonal antibodies
    • doi:10.1007/BF02256001
    • Liu HH, Chen KH, Shih YP, Lui WY, Wong FH, et al. (2003) Characterization of reduced expression of glycine N-methyltransferase in cancerous hepatic tissues using two newly developed monoclonal antibodies. J Biomed Sci 10: 87-97. doi:10.1007/BF02256001. PubMed: 12566990.
    • (2003) J Biomed Sci , vol.10 , pp. 87-97
    • Liu, H.H.1    Chen, K.H.2    Shih, Y.P.3    Lui, W.Y.4    Wong, F.H.5
  • 12
    • 0027859130 scopus 로고
    • Characterization of a new monoclonal antibody F4 detecting cell surface epitope and P-glycoprotein in drug-resistant human tumor cell lines
    • doi:10.1089/hyb.1993.12.417
    • Chu TM, Kawinski E, Lin TH, (1993) Characterization of a new monoclonal antibody F4 detecting cell surface epitope and P-glycoprotein in drug-resistant human tumor cell lines. Hybridoma 12: 417-429. doi:10.1089/hyb.1993.12.417. PubMed: 7503940.
    • (1993) Hybridoma , vol.12 , pp. 417-429
    • Chu, T.M.1    Kawinski, E.2    Lin, T.H.3
  • 13
    • 33644814231 scopus 로고    scopus 로고
    • NPC2 is expressed in human and murine liver and secreted into bile: potential implications for body cholesterol homeostasis
    • doi:10.1002/hep.20985
    • Klein A, Amigo L, Retamal MJ, Morales MG, Miquel JF, et al. (2006) NPC2 is expressed in human and murine liver and secreted into bile: potential implications for body cholesterol homeostasis. Hepatology 43: 126-133. doi:10.1002/hep.20985. PubMed: 16374838.
    • (2006) Hepatology , vol.43 , pp. 126-133
    • Klein, A.1    Amigo, L.2    Retamal, M.J.3    Morales, M.G.4    Miquel, J.F.5
  • 14
    • 4744347394 scopus 로고    scopus 로고
    • Niemann-Pick type C disease: importance of N-glycosylation sites for function and cellular location of the NPC2 protein
    • doi:10.1016/j.ymgme.2004.06.013
    • Chikh K, Vey S, Simonot C, Vanier MT, Millat G, (2004) Niemann-Pick type C disease: importance of N-glycosylation sites for function and cellular location of the NPC2 protein. Mol Genet Metab 83: 220-230. doi:10.1016/j.ymgme.2004.06.013. PubMed: 15542393.
    • (2004) Mol Genet Metab , vol.83 , pp. 220-230
    • Chikh, K.1    Vey, S.2    Simonot, C.3    Vanier, M.T.4    Millat, G.5
  • 15
    • 0036828228 scopus 로고    scopus 로고
    • Two-dimensional complementary deoxyribonucleic acid electrophoresis revealing up-regulated human epididymal protein-1 and down-regulated CL-100 in thyroid papillary carcinoma
    • doi:10.1210/en.2002-220550
    • Asakawa J, Kodaira M, Ishikawa N, Hirai Y, Nagataki S, et al. (2002) Two-dimensional complementary deoxyribonucleic acid electrophoresis revealing up-regulated human epididymal protein-1 and down-regulated CL-100 in thyroid papillary carcinoma. Endocrinology 143: 4422-4428. doi:10.1210/en.2002-220550. PubMed: 12399439.
    • (2002) Endocrinology , vol.143 , pp. 4422-4428
    • Asakawa, J.1    Kodaira, M.2    Ishikawa, N.3    Hirai, Y.4    Nagataki, S.5
  • 16
    • 84863724882 scopus 로고    scopus 로고
    • Locoregional recurrence after breast cancer surgery: a systematic review by receptor phenotype
    • doi:10.1007/s10549-011-1891-6
    • Lowery AJ, Kell MR, Glynn RW, Kerin MJ, Sweeney KJ, (2012) Locoregional recurrence after breast cancer surgery: a systematic review by receptor phenotype. Breast Cancer Res Treat 133: 831-841. doi:10.1007/s10549-011-1891-6. PubMed: 22147079.
    • (2012) Breast Cancer Res Treat , vol.133 , pp. 831-841
    • Lowery, A.J.1    Kell, M.R.2    Glynn, R.W.3    Kerin, M.J.4    Sweeney, K.J.5
  • 17
    • 80052699284 scopus 로고    scopus 로고
    • Female breast cancer status according to ER, PR and HER2 expression: a population based analysis
    • doi:10.1007/s12253-011-9381-z
    • Caldarella A, Crocetti E, Bianchi S, Vezzosi V, Urso C, et al. (2011) Female breast cancer status according to ER, PR and HER2 expression: a population based analysis. Pathol Oncol Res 17: 753-758. doi:10.1007/s12253-011-9381-z. PubMed: 21479875.
    • (2011) Pathol Oncol Res , vol.17 , pp. 753-758
    • Caldarella, A.1    Crocetti, E.2    Bianchi, S.3    Vezzosi, V.4    Urso, C.5
  • 18
    • 68249144780 scopus 로고    scopus 로고
    • Breast cancer subtypes based on ER/PR and Her2 expression: comparison of clinicopathologic features and survival
    • doi:10.3121/cmr.2008.825
    • Onitilo AA, Engel JM, Greenlee RT, Mukesh BN, (2009) Breast cancer subtypes based on ER/PR and Her2 expression: comparison of clinicopathologic features and survival. Clin Med Res 7: 4-13. doi:10.3121/cmr.2008.825. PubMed: 19574486.
    • (2009) Clin Med Res , vol.7 , pp. 4-13
    • Onitilo, A.A.1    Engel, J.M.2    Greenlee, R.T.3    Mukesh, B.N.4
  • 19
    • 33744960226 scopus 로고    scopus 로고
    • Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study
    • doi:10.1001/jama.295.21.2492
    • Carey LA, Perou CM, Livasy CA, Dressler LG, Cowan D, et al. (2006) Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA 295: 2492-2502. doi:10.1001/jama.295.21.2492. PubMed: 16757721.
    • (2006) JAMA , vol.295 , pp. 2492-2502
    • Carey, L.A.1    Perou, C.M.2    Livasy, C.A.3    Dressler, L.G.4    Cowan, D.5
  • 20
    • 73949101931 scopus 로고    scopus 로고
    • Respiratory disease in Niemann-Pick type C2 is caused by pulmonary alveolar proteinosis
    • doi:10.1111/j.1399-0004.2009.01325.x
    • Griese M, Brasch F, Aldana VR, Cabrera MM, Goelnitz U, et al. (2010) Respiratory disease in Niemann-Pick type C2 is caused by pulmonary alveolar proteinosis. Clin Genet 77: 119-130. doi:10.1111/j.1399-0004.2009.01325.x. PubMed: 20002450.
    • (2010) Clin Genet , vol.77 , pp. 119-130
    • Griese, M.1    Brasch, F.2    Aldana, V.R.3    Cabrera, M.M.4    Goelnitz, U.5
  • 21
    • 67651211612 scopus 로고    scopus 로고
    • Use of narrow-range peptide IEF to improve detection of lung adenocarcinoma markers in plasma and pleural effusion
    • doi:10.1002/pmic.200800814
    • Pernemalm M, De Petris L, Eriksson H, Brandén E, Koyi H, et al. (2009) Use of narrow-range peptide IEF to improve detection of lung adenocarcinoma markers in plasma and pleural effusion. Proteomics 9: 3414-3424. doi:10.1002/pmic.200800814. PubMed: 19609957.
    • (2009) Proteomics , vol.9 , pp. 3414-3424
    • Pernemalm, M.1    De Petris, L.2    Eriksson, H.3    Brandén, E.4    Koyi, H.5
  • 22
    • 80052581514 scopus 로고    scopus 로고
    • Lung cancer signatures in plasma based on proteome profiling of mouse tumor models
    • doi:10.1016/j.ccr.2011.08.007
    • Taguchi A, Politi K, Pitteri SJ, Lockwood WW, Faça VM, et al. (2011) Lung cancer signatures in plasma based on proteome profiling of mouse tumor models. Cancer Cell 20: 289-299. doi:10.1016/j.ccr.2011.08.007. PubMed: 21907921.
    • (2011) Cancer Cell , vol.20 , pp. 289-299
    • Taguchi, A.1    Politi, K.2    Pitteri, S.J.3    Lockwood, W.W.4    Faça, V.M.5
  • 23
    • 80455132074 scopus 로고    scopus 로고
    • Protein replacement therapy partially corrects the cholesterol-storage phenotype in a mouse model of Niemann-Pick type C2 disease
    • doi:10.1371/journal.pone.0027287
    • Nielsen GK, Dagnaes-Hansen F, Holm IE, Meaney S, Symula D, et al. (2011) Protein replacement therapy partially corrects the cholesterol-storage phenotype in a mouse model of Niemann-Pick type C2 disease. PLOS ONE 6: e27287. doi:10.1371/journal.pone.0027287. PubMed: 22073306.
    • (2011) PLOS ONE , vol.6
    • Nielsen, G.K.1    Dagnaes-Hansen, F.2    Holm, I.E.3    Meaney, S.4    Symula, D.5
  • 24
    • 77951456114 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection
    • doi:10.1002/hep.23594
    • Starley BQ, Calcagno CJ, Harrison SA, (2010) Nonalcoholic fatty liver disease and hepatocellular carcinoma: a weighty connection. Hepatology 51: 1820-1832. doi:10.1002/hep.23594. PubMed: 20432259.
    • (2010) Hepatology , vol.51 , pp. 1820-1832
    • Starley, B.Q.1    Calcagno, C.J.2    Harrison, S.A.3
  • 25
    • 0036780582 scopus 로고    scopus 로고
    • Pathogenesis of steatohepatitis
    • doi:10.1053/bega.2002.0333
    • Day CP, (2002) Pathogenesis of steatohepatitis. Best Pract Res Clin Gastroenterol 16: 663-678. doi:10.1053/bega.2002.0333. PubMed: 12406438.
    • (2002) Best Pract Res Clin Gastroenterol , vol.16 , pp. 663-678
    • Day, C.P.1
  • 26
    • 69249203477 scopus 로고    scopus 로고
    • Identification of NPC2 protein as interaction molecule with C2 domain of human Nedd4L
    • doi:10.1016/j.bbrc.2009.07.158
    • Araki N, Ishigami T, Ushio H, Minegishi S, Umemura M, et al. (2009) Identification of NPC2 protein as interaction molecule with C2 domain of human Nedd4L. Biochem Biophys Res Commun 388: 290-296. doi:10.1016/j.bbrc.2009.07.158. PubMed: 19664597.
    • (2009) Biochem Biophys Res Commun , vol.388 , pp. 290-296
    • Araki, N.1    Ishigami, T.2    Ushio, H.3    Minegishi, S.4    Umemura, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.