Potential role for phosphatidylinositol transfer protein (PITP) family in lipid transfer during phospholipase C signalling

Advances in Biological Regulation

Volumn 53, Issue 3, 2013, Pages 280-291

  Cockcroft, Shamshad ^a   Garner, Kathryn ^a,b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIA;

PHOSPHOLIPASE C; PHOSPHOLIPID TRANSFER PROTEIN;

ANIMAL; GENETICS; HUMAN; LIPID METABOLISM; METABOLISM; MULTIGENE FAMILY; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; HUMANS; LIPID METABOLISM; MULTIGENE FAMILY; PHOSPHOLIPID TRANSFER PROTEINS; SIGNAL TRANSDUCTION; TYPE C PHOSPHOLIPASES;

EID: 84885703200     PISSN: 22124926     EISSN: None     Source Type: Book Series    
DOI: 10.1016/j.jbior.2013.07.007     Document Type: Review

References (81)

1. Alfonso Pecchio A.R., Cardozo Gizzi A.M., Renner M.L., Molina-Calavita M., Caputto B.L. c-Fos activates and physically interacts with specific enzymes of the pathway of synthesis of polyphosphoinositides. Mol Biol Cell 2011, 22:4716-4725.
2. Allen-Baume V., Segui B., Cockcroft S. Current thoughts on the phosphatidylinositol transfer protein family. FEBS Lett 2002, 531:74-80.
3. Baird D., Stefan C., Audhya A., Weys S., Emr S.D. Assembly of the PtdIns 4-kinase Stt4 complex at the plasma membrane requires Ypp1 and Efr3. J Cell Biol 2008, 183:1061-1074.
4. Balla A., Kim Y.J., Varnai P., Szentpetery Z., Knight Z., Shokat K.M., et al. Maintenance of hormone-sensitive phosphoinositide pools in the plasma membrane requires phosphatidylinositol 4-kinase III{alpha}. Mol Biol Cell 2008, 19:711-721.
5. 2+ signaling in the retinal pigment epithelium: role of angiotensin-receptor-associated-protein and TRPV2 channel. PLoS ONE 2012, 7:e49624.
6. Bohdanowicz M., Schlam D., Hermansson M., Rizzuti D., Fairn G.D., Ueyama T., et al. Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes. Mol Biol Cell 2013, 24:1700-1712.
7. Cai J., Abramovici H., Gee S.H., Topham M.K. Diacylglycerol kinases as sources of phosphatidic acid. Biochim Biophys Acta 2009.
8. Chang J.T., Milligan S., Li Y., Chew C.E., Wiggs J., Copeland N.G., et al. Mammalian homolog of Drososphila retinal degeneration B rescues the mutant fly phenotype. J Neurosci 1997, 17:5881-5890.
9. Cockcroft S. Phosphatidic acid regulation of phosphatidylinositol 4-phosphate 5-kinases. Biochim Biophys Acta 2009, 1791:905-912.
10. 2+-activated polyphosphoinositide phosphodiesterase of human and rabbit neutrophil membranes. Biochem J 1984, 221:477-482.
11. Cockcroft S., Garner K. Function of the phosphatidylinositol transfer protein gene family: is phosphatidylinositol transfer the mechanism of action?. Crit Rev Biochem Mol Biol 2011, 46:89-117.
12. Connerth M., Tatsuta T., Haag M., Klecker T., Westermann B., Langer T. Intramitochondrial transport of phosphatidic acid in yeast by a lipid transfer protein. Science 2012, 338:815-818.
13. Cosker K.E., Shadan S., van Diepen M., Morgan C., Li M., Allen-Baume V., et al. Regulation of PI3K signalling by the phosphatidylinositol transfer protein PITP{alpha} during axonal extension in hippocampal neurons. J Cell Sci 2008, 121:796-803.
14. Cunningham E., Tan S.W., Swigart P., Hsuan J., Bankaitis V., Cockcroft S. The yeast and mammalian isoforms of phosphatidylinositol transfer protein can all restore phospholipase C-mediated inositol lipid signalling in cytosol-depleted RBL-2H3 and HL60 cells. Proc Natl Acad Sci U S A 1996, 93:6589-6593.
15. 2. Curr Biol 1995, 5:775-783.
16. Daviet L., Lehtonen J.Y., Tamura K., Griese D.P., Horiuchi M., Dzau V.J. Cloning and characterization of ATRAP, a novel protein that interacts with the angiotensin II type 1 receptor. J Biol Chem 1999, 274:17058-17062.
17. Dickson E.J., Falkenburger B.H., Hille B. Quantitative properties and receptor reserve of the IP3 and calcium branch of Gq-coupled receptor signaling. J Gen Physiol 2013, 141:521-535.
18. English A.R., Voeltz G.K. Rab10 GTPase regulates ER dynamics and morphology. Nat Cell Biol 2013, 15:169-178.
19. Falkenburger B.H., Dickson E.J., Hille B. Quantitative properties and receptor reserve of the DAG and PKC branch of Gq-coupled receptor signaling. J Gen Physiol 2013, 141:537-555.
20. 2 synthesis. Curr Biol 1996, 6:730-738.
21. Fullwood Y., dos Santos M., Hsuan J.J. Cloning and characterization of a novel human phosphatidylinositol transfer protein, RgdBβ. J Biol Chem 1999, 274:31553-31558.
22. Garner K., Hunt A.N., Koster G., Somerharju P., Grover E., Li M., et al. Phosphatidylinositol transfer protein, cytoplasmic 1 (PITPNC1) binds and transfers phosphatidic acid. J Biol Chem 2012, 287:32263-32276.
23. Garner K., Li M., Ugwuanya N., Cockcroft S. The phosphatidylinositol transfer protein, RdgBβ binds 14-3-3 via its unstructured C-terminus, whereas its lipid binding domain interacts with the integral membrane protein, ATRAP (Angiotensin II Type I receptor-associated protein). Biochem J 2011, 439:97-111.
24. 2-dependent and Ca(2+)-regulated ER-PM interactions mediated by the extended synaptotagmins. Cell 2013, 153:1494-1509.
25. Guo S., Lopez-Ilasaca M., Dzau V.J. Identification of calcium-modulating cyclophilin ligand (CAML) as transducer of angiotensin II-mediated nuclear factor of activated T cells (NFAT) activation. J Biol Chem 2005, 280:12536-12541.
26. Halford S., Dulai K.S., Daw S.C., Fitzgibbon J., Hunt D.M. Isolation and chromosomal localization of two human CDP-diacylglycerol synthase (CDS) genes. Genomics 1998, 54:140-144.
27. Hardie R.C., Raghu P., Moore S., Juusola M., Baines R.A., Sweeney S.T. Calcium influx via TRP channels is required to maintain PIP2 levels in Drosophila photoreceptors. Neuron 2001, 30:149-159.
28. 2+-activated secretion. Nature 1995, 374:173-177.
29. 2+-activated secretion. Nature 1993, 366:572-575.
30. Inglis-Broadgate S.L., Ocaka L., Banerjee R., Gaasenbeek M., Chapple J.P., Cheetham M.E., et al. Isolation and characterization of murine Cds (CDP-diacylglycerol synthase) 1 and 2. Gene 2005, 356:19-31.
31. Kauffmann-Zeh A., Thomas G.M.H., Ball A., Prosser S., Cunningham E., Cockcroft S., et al. Requirement for phosphatidylinositol transfer protein in epidermal growth factor signalling. Science 1995, 268:1188-1190.
32. Kim Y.J., Guzman-Hernandez M.L., Balla T. A highly dynamic ER-derived phosphatidylinositol - synthesizing organelle supplies phosphoinositides to cellular membranes. Dev Cell 2011, 21:813-824.
33. Lee Y.J., Shah S., Suzuki E., Zars T., O'Day P.M., Hyde D.R. The Drosophila dgq gene encodes a G alpha protein that mediates phototransduction. Neuron 1994, 13:1143-1157.
34. Lopez-Ilasaca M., Liu X., Tamura K., Dzau V.J. The angiotensin II type I receptor-associated protein, ATRAP, is a transmembrane protein and a modulator of angiotensin II signaling. Mol Biol Cell 2003, 14:5038-5050.
35. Lydikis A., Jackson P.D., Rock C.O., Jackowski S. The role of CDP-diacylglycerol synthase and phosphatidylinositol synthase activity levels in the regulation of cellular phosphatidylinositol content. J Biol Chem 1997, 272:33402-33409.
36. Manford A.G., Stefan C.J., Yuan H.L., Macgurn J.A., Emr S.D. ER-to-plasma membrane tethering proteins regulate cell signaling and ER morphology. Dev Cell 2012, 23:1129-1140.
37. Masai I., Suzuki E., Yoon C.S., Kohyama A., Hotta Y. Immunolocalization of Drosophila eye-specific diacylgylcerol kinase, rdgA, which is essential for the maintenance of the photoreceptor. J Neurobiol 1997, 32:695-706.
38. Merida I., Avila-Flores A., Merino E. Diacylglycerol kinases: at the hub of cell signalling. Biochem J 2008, 409:1-18.
39. Michell R.H. Inositol phospholipids in cell surface receptor function. Biochim Biophys Acta 1975, 415:81-147.
40. Milligan S.C., Alb J.G., Elagina R.B., Bankaitis V.A., Hyde D.R. The phosphatidylinositol transfer protein domain of Drosophila retinal degeneration B protein is essential for photoreceptor cell survival and recovery from light stimulation. J Cell Biol 1997, 139:351-363.
41. Murphy T.R., Vihtelic T.S., Ile K.E., Watson C.T., Willer G.B., Gregg R.G., et al. Phosphatidylinositol synthase is required for lens structural integrity and photoreceptor cell survival in the zebrafish eye. Exp Eye Res 2011, 93:460-474.
42. Nakatsu F., Baskin J.M., Chung J., Tanner L.B., Shui G., Lee S.Y., et al. PtdIns4P synthesis by PI4KIIIalpha at the plasma membrane and its impact on plasma membrane identity. J Cell Biol 2012, 199:1003-1016.
43. Niizeki T., Takeishi Y., Kitahara T., Arimoto T., Koyama Y., Goto K., et al. Diacylglycerol kinase zeta rescues G alpha q-induced heart failure in transgenic mice. Circ J 2008, 72:309-317.
44. Nile A.H., Bankaitis V.A., Grabon A. Mammalian diseases of phosphatidylinositol transfer proteins and their homologs. Clin Lipidol 2010, 5:867-897.
45. Oppermann M., Gess B., Schweda F., Castrop H. Atrap deficiency increases arterial blood pressure and plasma volume. J Am Soc Nephrol 2010, 21:468-477.
46. Paetkau D.W., Elagin V.A., Sendi L.M., Hyde D.R. Isolation and characterization of Drosophila retinal degeneration B suppressors. Genetics 1999, 151:713-724.
47. Pan W., Pham V.N., Stratman A.N., Castranova D., Kamei M., Kidd K.R., et al. CDP-diacylglycerol synthase-controlled phosphoinositide availability limits VEGFA signaling and vascular morphogenesis. Blood 2012, 120:489-498.
48. Pettitt T.R., Martin A., Horton T., Liossis C., Lord J.M., Wakelam M.J. Diacylglycerol and phosphatidate generated by phospholipases C and D, respectively, have distinct fatty acid compositions and functions. Phospholipase D-derived diacylglycerol does not activate protein kinase C in porcine aortic endothelial cells. J Biol Chem 1997, 272:17354-17359.
49. Raghu P., Yadav S., Mallampati N.B. Lipid signaling in Drosophila photoreceptors. Biochim Biophys Acta 2012, 1821:1154-1165.
50. Rechsteiner M., Rogers S.W. PEST sequences and regulation by proteolysis. Trends Biochem Sci 1996, 21:267-271.
51. Rogers S., Wells R., Rechsteiner M. Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis. Science 1986, 234:364-368.
52. Schouten A., Agianian B., Westerman J., Kroon J., Wirtz K.W., Gros P. Structure of apo-phosphatidylinositol transfer protein alpha provides insight into membrane association. EMBO J 2002, 21:2117-2121.
53. Sengupta S., Barber T.R., Xia H., Ready D.F., Hardie R.C. Depletion of PtdIns(4,5)P2 underlies retinal degeneration in Drosophila trp mutants. J Cell Sci 2013, 126:1247-1259.
54. Shadan S., Holic R., Carvou N., Ee P., Li M., Murray-Rust J., et al. Dynamics of lipid transfer by phosphatidylinositol transfer proteins in cells. Traffic 2008, 9:1743-1756.
55. 2+ entry. J Biol Chem 2011, 286:36448-36459.
56. Shen W.W., Frieden M., Demaurex N. Remodelling of the endoplasmic reticulum during store-operated calcium entry. Biol Cell 2011, 103:365-380.
57. Shulga Y.V., Topham M.K., Epand R.M. Regulation and functions of diacylglycerol kinases. Chem Rev 2011, 111:6186-6208.
58. Stark W.S., Sapp R. Ultrastructure of the retina of Drosophila melanogaster: the mutant ora (outer rhabdomeres absent) and its inhibition of degeneration in rdgB (retinal degeneration-B). J Neurogenet 1987, 4:227-240.
59. Stefan C.J., Manford A.G., Baird D., Yamada-Hanff J., Mao Y., Emr S.D. Osh proteins regulate phosphoinositide metabolism at ER-plasma membrane contact sites. Cell 2011, 144:389-401.
60. Stefan C.J., Manford A.G., Emr S.D. ER-PM connections: sites of information transfer and inter-organelle communication. Curr Opin Cell Biol 2013.
61. Takano N., Owada Y., Suzuki R., Sakagami H., Shimosegawa T., Kondo H. Cloning and characterization of a novel variant (mM-rdgBbeta1) of mouse M-rdgBs, mammalian homologs of Drosophila retinal degeneration B gene proteins, and its mRNA localization in mouse brain in comparison with other M-rdgBs. J Neurochem 2003, 84:829-839.
62. Takeishi Y., Goto K., Kubota I. Role of diacylglycerol kinase in cellular regulatory processes: a new regulator for cardiomyocyte hypertrophy. Pharmacol Ther 2007, 115:352-359.
63. Tamura Y., Harada Y., Nishikawa S.I., Yamano K., Kamiya M., Shiota T., et al. Tam41 is a CDP-diacylglycerol synthase required for cardiolipin biosynthesis in mitochondria. Cell Metab 2013, 17:1-10.
64. Thakur P.C., Stuckenholz C., Rivera M.R., Davison J.M., Yao J.K., Amsterdam A., et al. Lack of de novo phosphatidylinositol synthesis leads to endoplasmic reticulum stress and hepatic steatosis in cdipt-deficient zebrafish. Hepatology 2011, 54:452-462.
65. Thomas G.M.H., Cunningham E., Fensome A., Ball A., Totty N.F., Troung O., et al. An essential role for phosphatidylinositol transfer protein in phospholipase C-mediated inositol lipid signalling. Cell 1993, 74:919-928.
66. Tilley S.J., Skippen A., Murray-Rust J., Swigart P., Stewart A., Morgan C.P., et al. Structure-function analysis of human phosphatidylinositol transfer protein alpha bound to phosphatidylinositol. Structure 2004, 12:317-326.
67. Tomioka M., Adachi T., Suzuki H., Kunitomo H., Schafer W.R., Iino Y. The insulin/PI 3-kinase pathway regulates salt chemotaxis learning in Caenorhabditis elegans. Neuron 2006, 51:613-625.
68. Trivedi D., Padinjat R. RdgB proteins: functions in lipid homeostasis and signal transduction. Biochim Biophys Acta 2007, 1771:692-699.
69. van dB I., Divecha N. PIP5K-driven PtdIns(4,5)P2 synthesis: regulation and cellular functions. J Cell Sci 2009, 122:3837-3850.
70. Vihtelic T.S., Goebl M., Milligan S., O'Tousa S.E., Hyde D.R. Localization of Drosophila retinal degeneration B, a membrane-associated phosphatidylinositol transfer protein. J Cell Biol 1993, 122:1013-1022.
71. Vordtriede P.B., Doan C.N., Tremblay J.M., Helmkamp G.M., Yoder M.D. Structure of PITPβ in complex with phosphatidylcholine: comparison of structure and lipid transfer to other PITP isoforms. Biochemistry 2005, 44:14760-14771.
72. Wakui H., Tamura K., Tanaka Y., Matsuda M., Bai Y., Dejima T., et al. Cardiac-specific activation of angiotensin II type 1 receptor-associated protein completely suppresses cardiac hypertrophy in chronic angiotensin II-infused mice. Hypertension 2010, 55:1157-1164.
73. Wang T., Montell C. A phosphoinositide synthase required for a sustained light response. J Neurosci 2006, 26:12816-12825.
74. Wang W., Huang Y., Zhou Z., Tang R., Zhao W., Zeng L., et al. Identification and characterization of AGTRAP, a human homolog of murine Angiotensin II Receptor-Associated Protein (Agtrap). Int J Biochem Cell Biol 2002, 34:93-102.
75. Wang Y., Chen X., Lian L., Tang T., Stalker T.J., Sasaki T., et al. Loss of PIP5KIbeta demonstrates that PIP5KI isoform-specific PIP2 synthesis is required for IP3 formation. Proc Natl Acad Sci U S A 2008, 105:14064-14069.
76. Waugh M.G., Minogue S., Clayton E.L., Hsuan J.J. CDP-diacylglycerol phospholipid synthesis in detergent-soluble, non-raft, membrane microdomains of the endoplasmic reticulum. J Lipid Res 2011, 52:2148-2158.
77. Whatmore J., Wiedemann C., Somerharju P., Swigart P., Cockcroft S. Resynthesis of phosphatidylinositol in permeabilised neutrophils following phospholipase Cβ activation: transport of the intermediate, phosphatidic acid from the plasma membrane to the endoplasmic reticulum for phosphatidylinositol resynthesis is not dependent on soluble lipid carriers or vesicular transport. Biochem J 1999, 341:435-444.
78. Wu L., Niemeyer B., Colley N., Socolich M., Zuker C.S. Regulation of PLC-mediated signalling invivo by CDP-diacylglycerol synthase. Nature 1995, 373:216-222.
79. Xie Y., Ding Y.-Q., Hong Y., Feng Z., navarre S., Xi C.-X., et al. Role of phosphatidylinositol transfer protein α in netrin-1-induced PLC signalling and neurite outgrowth. Nat Cell Biol 2005, 7:1124-1132.
80. Xie Y., Hong Y., Ma X.Y., Ren X.R., Ackerman S., Mei L., et al. DCC-dependent phospholipase C signaling in netrin-1-induced neurite elongation. J Biol Chem 2006, 281:2605-2611.
81. Yoder M.D., Thomas L.M., Tremblay J.M., Oliver R.L., Yarbrough L.R., Helmkamp G.M. Structure of a multifunctional protein. Mammalian phosphatidylinositol transfer protein complexed with phosphatidylcholine. J Biol Chem 2001, 276:9246-9252.