Western-type diet induces senescence, modifies vascular function in non-senescence mice and triggers adaptive mechanisms in senescent ones

Experimental Gerontology

Volumn 48, Issue 12, 2013, Pages 1410-1419

  Onetti, Yara ^a   Jiménez Altayó, Francesc ^a   Heras, Magda ^b   Vila, Elisabet ^a   Dantas, Ana Paula ^b  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

Author keywords

Endothelium; High fat diet; Nitric oxide; Prostaglandins; Vascular senescence

Indexed keywords

BETA GALACTOSIDASE; CYCLOOXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXYGEN; PEROXYNITRITE; PHENYLALANINE; PROSTAGLANDIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; AORTA; ARTERY CONSTRICTION; ARTICLE; BLOOD VESSEL FUNCTION; CONTROLLED STUDY; DIET; FEMALE; LIPID DIET; MOUSE; MOUSE STRAIN; NON SENESCENCE ACCELERATED MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE; SENESCENCE ACCELERATED MOUSE; SIGNAL TRANSDUCTION; STAINING; VASOCONSTRICTION; VASODILATATION; WESTERN TYPE DIET;

ENDOTHELIUM; HIGH-FAT DIET; NITRIC OXIDE; PROSTAGLANDINS; VASCULAR SENESCENCE;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; AORTA, THORACIC; CELL AGING; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DIET, HIGH-FAT; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION REGULATION; GENOTYPE; HYDROGEN PEROXIDE; MEMBRANE PROTEINS; MICE; NADPH OXIDASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; PHENOTYPE; PROSTAGLANDINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; SUPEROXIDES; TIME FACTORS; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS;

EID: 84885701382     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2013.09.004     Document Type: Article

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