Pretreatment with pyridoxamine mitigates isolevuglandinassociated retinal effects in mice exposed to bright light

Journal of Biological Chemistry

Volumn 288, Issue 41, 2013, Pages 29267-29280

  Charvet, Casey D ^a   Saadane, Aicha ^a   Wang, Meiyao ^b,c   Salomon, Robert G ^a   Brunengraber, Henri ^a   Turko, Illarion V ^b,c   Pikuleva, Irina A ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^c NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGE-RELATED MACULAR DEGENERATION; ANTIOXIDANT THERAPIES; LIPID PEROXIDATION; MORPHOLOGICAL CHANGES; REACTIVE OXYGEN INTERMEDIATES; RETINAL DISEASE; THERAPEUTIC TARGETS; VISION RESEARCH;

ANTIOXIDANTS; MAMMALS; OPHTHALMOLOGY; OXIDATIVE STRESS; PHOSPHOLIPIDS; SCAVENGING;

BIOMOLECULES;

ALDEHYDE DERIVATIVE; GAMMA KETOALDEHYDE; ISOLEVUGLANDIN; PROSTAGLANDIN DERIVATIVE; PYRIDOXAMINE; PYRIDOXINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; DRUG SAFETY; DRUG STRUCTURE; FEMALE; FLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; LIGHT EXPOSURE; LIPID PEROXIDATION; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RETINA INJURY; TISSUE LEVEL; TREATMENT OUTCOME; VITAMIN BLOOD LEVEL;

AGE-RELATED MACULAR DEGENERATION; ISOLEVUGLANDIN; LIPID PEROXIDATION; MASS SPECTROMETRY (MS); MITOCHONDRIA; OXIDATIVE STRESS; PYRIDOXAMINE; RETINAL DEGENERATION; VITAMIN B6;

AGED; ANIMALS; EYE; FATTY ACIDS, UNSATURATED; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LIGHT; MACULAR DEGENERATION; MICE; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; PYRIDOXAMINE; RETINA; VITAMIN B COMPLEX;

EID: 84885666328     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.498832     Document Type: Article

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