Axonal transport deficit in the optic nerve of rats with inherited retinitis pigmentosa and experimentally induced glaucoma

Graefe's Archive for Clinical and Experimental Ophthalmology

Volumn 246, Issue 11, 2008, Pages 1553-1558

  Sposato, Valentina ^a   Iovieno, Alfonso ^b   Sornelli, Federica ^a   Aloe, Luigi ^a  

^a CNR   (Italy)

^b UNIVERSITY CAMPUS BIO MEDICO   (Italy)

Author keywords

Axonal transport; Glaucoma; Retinal ganglion cell; Retinitis pigmentosa; Rhodamine

Indexed keywords

DEXTRAN TETRAMETHYLRHODAMINE; DYE; FLUORESCENT DYE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL LOSS; CONTROLLED STUDY; GLAUCOMA; INTRAOCULAR HYPERTENSION; MALE; NONHUMAN; OPTIC NERVE DISEASE; PHOTORECEPTOR CELL; PRIORITY JOURNAL; RAT; RETINA DEGENERATION; RETINA GANGLION CELL; RETINITIS PIGMENTOSA; RETROGRADE NERVE FIBER TRANSPORT; SPRAGUE DAWLEY RAT;

ANIMALS; AXONAL TRANSPORT; BIOLOGICAL TRANSPORT, ACTIVE; CELL COUNT; COLORING AGENTS; DEXTRANS; DISEASE MODELS, ANIMAL; GLAUCOMA; INTRAOCULAR PRESSURE; MALE; OPTIC NERVE; RATS; RATS, INBRED STRAINS; RATS, SPRAGUE-DAWLEY; RETINA; RETINAL GANGLION CELLS; RETINITIS PIGMENTOSA; RHODAMINES; SALINE SOLUTION, HYPERTONIC;

EID: 54049112590     PISSN: 0721832X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00417-008-0903-7     Document Type: Article

References (29)

1. Amendola T, Aloe L (2002) Developmental expression of nerve growth factor in the eye of rats affected by inherited retinopathy: Correlative aspects with retinal structural degeneration. Arch Ital Biol 140:81-90
2. Amendola T, Fiore M, Aloe L (2003) Postnatal changes in nerve growth factor and brain derived neurotrophic factor levels in the retina, visual cortex, and geniculate nucleus in rats with retinitis pigmentosa. Neurosci Lett 345:37-40, doi: 10.1016/S0304-3940(03)00491-9
3. Bakalash S, Kessler A, Mizrahi T, Nussenblatt R, Schwartz M (2003) Antigenic specificity of immunoprotective therapeutic vaccination for glaucoma. Invest Ophthalmol Vis Sci 44:3374-3381
4. Bakalash S, Rolls A, Lider O, Schwartz M (2007) Chondroitin sulfate-derived disaccharide protects retinal cells from elevated intraocular pressure in aged and immunocompromised rats. Invest Ophthalmol Vis Sci 48:1181-1190, doi: 10.1167/iovs.05-1213
5. Chen ZS, Yin ZQ, Chen S, Wang SJ (2005) Electrophysiological changes of retinal ganglion cells in Royal College of Surgeons rats during retinal degeneration. Neuroreport 16:971-975, doi: 10.1097/ 00001756-200506210-00018
6. Daiger SP, Bowne SJ, Sullivan LS (2007) Perspective on genes and mutations causing retinitis pigmentosa. Arch Ophthalmol 125(2):151-158, doi: 10.1001/archopht.125.2.151
7. D'Cruz PM, Yasumura D, Weir J, Matthes MT, Abderrahim H, LaVail MM et al (2000) Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat. Hum Mol Genet 9(4):645-651, doi: 10.1093/hmg/ 9.4.645
8. Eitan S, Solomon A, Lavie V, Yoles E, Hirschberg DL, Belkin M et al (1994) Recovery of visual response of injured adult rat optic nerves treated with transglutaminase. Science 264:1764-1768, doi: 10.1126/ science.7911602
9. Fritzsch B (1993) Fast axonal diffusion of 3000 molecular weight dextran amines. J Neurosci Methods 50:95-103, doi: 10.1016/0165-0270(93)90060-5
10. Gal A, Li Y, Thompson DA, Weir J, Orth U, Jacobson SG et al (2000) Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa. Nat Genet 26:270-271, doi: 10.1038/80002
11. Gartner S, Henkind P (1982) Pathology of retinitis pigmentosa. Ophthalmology 89:1425-1432
12. Hanitzsch R, Zeumer C, Lichtenberger T, Wurziger K (1998) Impaired function of bipolar cell in the Royal College of Surgeons rat. Acta Anat (Basel) 162:119-126, doi: 10.1159/000046476
13. Hare W, WoldeMussie E, Lai R, Ton H, Ruiz G, Feldmann B et al (2001) Efficacy and safety of memantine, an NMDA-type open-channel blocker, for reduction of retinal injury associated with experimental glaucoma in rat and monkey. Surv Ophthalmol 45(Suppl 3):S284-S289 discussion S295-296, doi: 10.1016/S0039-6257(01)00200-4
14. Hartong DT, Berson EL, Dryja TP (2006) Retinitis pigmentosa. Lancet 368(9549):1795-1809
15. Lenzi L, Coassin M, Lambiase A, Bonini S, Amendola T, Aloe L (2005) Effect of exogenous administration of nerve growth factor in the retina of rats with inherited retinitis pigmentosa. Vision Res 45:1491-1500, doi: 10.1016/j.visres.2004.12.020
16. Li ZY, Possin DE, Milam AH (1995) Histopathology of bone spicule pigmentation in retinitis pigmentosa. Ophthalmology 102:805-816,
17. Milam AH, Li ZY, Fariss RN (1998) Histopathology of the human retina in retinitis pigmentosa. Prog Retin Eye Res 17:175-205, doi: 10.1016/ S1350-9462(97)00012-8
18. Minckler DS, Bunt AH, Johanson GW (1977) Orthograde and retrograde axoplasmic transport during acute ocular hypertension in the monkey. Invest Ophthalmol Vis Sci 16(5):426-441
19. Otani A, Dorrell MI, Kinder K, Moreno SK, Nusinowitz S, Banin E et al (2004) Rescue of retinal degeneration by intravitreally injected adult bone marrow-derived lineage-negative hematopoietic stem cells. J Clin Invest 114(6):756-774
20. Morrison JC, Johnson EC, Cepurna W, Jia L (2005) Understanding mechanisms of pressure-induced optic nerve damage. Prog Retin Eye Res 24:217-240, doi: 10.1016/j.preteyeres.2004.08.003
21. Newman NM, Stevens RA, Heckenlively JR (1987) Nerve fibre layer loss in diseases of the outer retinal layer. Br J Ophthalmol 71:21-26, doi: 10.1136/bjo.71.1.21
22. Solomon AS, Lavie V, Hauben U, Monsonego A, Yoles E, Schwartz M (1996) Complete transection of rat optic nerve while sparing the meninges and the vasculature: An experimental model for optic nerve neuropathy and trauma. J Neurosci Methods 70:21-25, doi: 10.1016/S0165-0270(96)00098-2
23. Steinberg RH (1994) Survival factors in retinal degenerations. Curr Opin Neurobiol 4:515-524, doi: 10.1016/0959-4388(94)90052-3
24. Stone JL, Barlow WE, Humayun MS, de Juan E Jr, Milam AH (1992) Morphometric analysis of macular photoreceptors and ganglion cells in retinas with retinitis pigmentosa. Arch Ophthalmol 110:1634-1639
25. Villegas-Pérez MP, Lawrence JM, Vidal-Sanz M, Lavail MM, Lund RD (1998) Ganglion cell loss in RCS rat retina: A result of compression of axons by contracting intraretinal vessels linked to the pigment epithelium. J Comp Neurol 392:58-77, doi: 10.1002/ (SICI)1096-9861(19980302)392:1<58::AID-CNE5>3.0.CO;2-O
26. Villegas-Pérez MP, Vidal-Sanz M, Lund RD (1996) Mechanism of retinal ganglion cell loss in inherited retinal dystrophy. Neuroreport 7:1995-1999, doi: 10.1097/00001756-199608120-00028
27. Walia S, Fishman GA, Edward DP, Lindeman M (2007) Retinal nerve fiber layer defects in RP patients. Invest Ophthalmol Vis Sci 48:4748-4752, doi: 10.1167/iovs.07-0404
28. Wang DY, Chan WM, Tam PO, Baum L, Lam DS, Chong KK et al (2005) Gene mutations in retinitis pigmentosa and their clinical implications. Clin Chim Acta 351:5-16, doi: 10.1016/j.cccn.2004.08.004
29. WoldeMussie E, Ruiz G, Wijono M, Wheeler LA (2001) Neuroprotection of retinal ganglion cells by brimonidine in rats with laser-induced chronic ocular hypertension. Invest Ophthalmol Vis Sci 42:2849-2855