-
1
-
-
0028303977
-
Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway
-
2-s2.0-0028303977
-
Akira S., Nishio Y., Inoue M., Wang X. J., Wei S., Matsusaka T., Yoshida K., Sudo T., Naruto M., Kishimoto T., Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway. Cell 1994 77 1 63 71 2-s2.0-0028303977
-
(1994)
Cell
, vol.77
, Issue.1
, pp. 63-71
-
-
Akira, S.1
Nishio, Y.2
Inoue, M.3
Wang, X.J.4
Wei, S.5
Matsusaka, T.6
Yoshida, K.7
Sudo, T.8
Naruto, M.9
Kishimoto, T.10
-
2
-
-
0028349735
-
Stat3: A STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6
-
Zhong Z., Wen Z., Darnell J. E. Jr., Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 1994 264 5155 95 98 2-s2.0-0028349735 (Pubitemid 24144493)
-
(1994)
Science
, vol.264
, Issue.5155
, pp. 95-98
-
-
Zhong, Z.1
Wen, Z.2
Darnell Jr., J.E.3
-
3
-
-
68949131070
-
+ T helper cell differentiation and inflammatory diseases
-
2-s2.0-68949131070 10.1016/j.cyto.2009.07.003
-
+ T helper cell differentiation and inflammatory diseases. Cytokine 2009 47 3 149 156 2-s2.0-68949131070 10.1016/j.cyto.2009.07.003
-
(2009)
Cytokine
, vol.47
, Issue.3
, pp. 149-156
-
-
Egwuagu, C.E.1
-
4
-
-
0030935260
-
Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality
-
DOI 10.1073/pnas.94.8.3801
-
Takeda K., Noguchi K., Shi W., Tanaka T., Matsumoto M., Yoshida N., Kishimoto T., Akira S., Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality. Proceedings of the National Academy of Sciences of the United States of America 1997 94 8 3801 3804 2-s2.0-0030935260 10.1073/pnas.94.8.3801 (Pubitemid 27180453)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.8
, pp. 3801-3804
-
-
Takeda, K.1
Noguchi, K.2
Shi, W.3
Tanaka, T.4
Matsumoto, M.5
Yoshida, N.6
Kishimoto, T.7
Akira, S.8
-
5
-
-
0037799912
-
Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice
-
DOI 10.1172/JCI200317085
-
Kobayashi M., Kweon M. N., Kuwata H., Schreiber R. D., Kiyono H., Takeda K., Akira S., Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice. Journal of Clinical Investigation 2003 111 9 1297 1308 2-s2.0-0037799912 10.1172/JCI200317085 (Pubitemid 36554700)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.9
, pp. 1297-1308
-
-
Kobayashi, M.1
Kweon, M.-N.2
Kuwata, H.3
Schreiber, R.D.4
Kiyono, H.5
Takeda, K.6
Akira, S.7
-
6
-
-
37749021324
-
Cutting edge: An in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity
-
2-s2.0-37749021324
-
Harris T. J., Grosso J. F., Yen H. R., Xin H., Kortylewski M., Albesiano E., Hipkiss E. L., Getnet D., Goldberg M. V., Maris C. H., Housseau F., Yu H., Pardoll D. M., Drake C. G., Cutting edge: an in vivo requirement for STAT3 signaling in TH17 development and TH17-dependent autoimmunity. Journal of Immunology 2007 179 7 4313 4317 2-s2.0-37749021324
-
(2007)
Journal of Immunology
, vol.179
, Issue.7
, pp. 4313-4317
-
-
Harris, T.J.1
Grosso, J.F.2
Yen, H.R.3
Xin, H.4
Kortylewski, M.5
Albesiano, E.6
Hipkiss, E.L.7
Getnet, D.8
Goldberg, M.V.9
Maris, C.H.10
Housseau, F.11
Yu, H.12
Pardoll, D.M.13
Drake, C.G.14
-
7
-
-
44449136105
-
+ T cells prevents development of experimental autoimmune diseases
-
2-s2.0-44449136105
-
+ T cells prevents development of experimental autoimmune diseases. Journal of Immunology 2008 180 9 6070 6076 2-s2.0-44449136105
-
(2008)
Journal of Immunology
, vol.180
, Issue.9
, pp. 6070-6076
-
-
Liu, X.1
Lee, Y.S.2
Yu, C.R.3
Egwuagu, C.E.4
-
8
-
-
34247593586
-
STAT3 regulates cytokine-mediated generation of inflammatory helper T cells
-
DOI 10.1074/jbc.C600321200
-
Yang X. O., Panopoulos A. D., Nurieva R., Seon H. C., Wang D., Watowich S. S., Dong C., STAT3 regulates cytokine-mediated generation of inflammatory helper T cells. The Journal of Biological Chemistry 2007 282 13 9358 9363 2-s2.0-34247593586 10.1074/jbc.C600321200 (Pubitemid 47104613)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.13
, pp. 9358-9363
-
-
Yang, X.O.1
Panopoulos, A.D.2
Nurieva, R.3
Seon, H.C.4
Wang, D.5
Watowich, S.S.6
Dong, C.7
-
9
-
-
0032213273
-
Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: Generation and characterization of T cell- specific stat3-deficient mice
-
Takeda K., Kaisho T., Yoshida N., Takeda J., Kishimoto T., Akira S., Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice. Journal of Immunology 1998 161 9 4652 4660 2-s2.0-0032213273 (Pubitemid 28492039)
-
(1998)
Journal of Immunology
, vol.161
, Issue.9
, pp. 4652-4660
-
-
Takeda, K.1
Kaisho, T.2
Yoshida, N.3
Takeda, J.4
Kishimoto, T.5
Akira, S.6
-
10
-
-
80052235701
-
STAT3 promotes T-cell survival and inhibits IL-2 production through up-regulation of class O forkhead transcription factors
-
2-s2.0-80052235701 10.1074/jbc.M111.253500
-
Oh H. M., Yu C. R., Golestaneh N., Amadi-Obi A., Lee Y. S., Eseonu A., Mahdi R. M., Egwuagu C. E., STAT3 promotes T-cell survival and inhibits IL-2 production through up-regulation of class O forkhead transcription factors. The Journal of Biological Chemistry 2011 286 35 30888 30897 2-s2.0-80052235701 10.1074/jbc.M111.253500
-
(2011)
The Journal of Biological Chemistry
, vol.286
, Issue.35
, pp. 30888-30897
-
-
Oh, H.M.1
Yu, C.R.2
Golestaneh, N.3
Amadi-Obi, A.4
Lee, Y.S.5
Eseonu, A.6
Mahdi, R.M.7
Egwuagu, C.E.8
-
11
-
-
23244464478
-
Gamma interferon can block herpes simplex virus type 1 reactivation from latency, even in the presence of late gene expression
-
DOI 10.1128/JVI.79.16.10339-10347.2005
-
Decman V., Kinchington P. R., Harvey S. A. K., Hendricks R. L., Gamma interferon can block herpes simplex virus type 1 reactivation from latency, even in the presence of late gene expression. Journal of Virology 2005 79 16 10339 10347 2-s2.0-23244464478 10.1128/JVI.79.16.10339-10347.2005 (Pubitemid 41098574)
-
(2005)
Journal of Virology
, vol.79
, Issue.16
, pp. 10339-10347
-
-
Decman, V.1
Kinchington, P.R.2
Harvey, S.A.K.3
Hendricks, R.L.4
-
12
-
-
80053057982
-
+ T lymphocytes that mediate chronic uveitis reside in the bone marrow through STAT3-dependent mechanisms
-
2-s2.0-80053057982 10.4049/jimmunol.1004019
-
+ T lymphocytes that mediate chronic uveitis reside in the bone marrow through STAT3-dependent mechanisms. Journal of Immunology 2011 187 6 3338 3346 2-s2.0-80053057982 10.4049/jimmunol.1004019
-
(2011)
Journal of Immunology
, vol.187
, Issue.6
, pp. 3338-3346
-
-
Oh, H.M.1
Yu, C.R.2
Lee, Y.3
Chan, C.C.4
Maminishkis, A.5
Egwuagu, C.E.6
-
13
-
-
82255186870
-
Persistence of IL-2 expressing Th17 cells in healthy humans and experimental autoimmune uveitis
-
2-s2.0-82255186870 10.1002/eji.201141654
-
Yu C. R., Oh H. M., Golestaneh N., Amadi-Obi A., Lee Y. S., Eseonu A., Mahdi R. M., Egwuagu C. E., Persistence of IL-2 expressing Th17 cells in healthy humans and experimental autoimmune uveitis. European Journal of Immunology 2011 41 12 3495 3505 2-s2.0-82255186870 10.1002/eji.201141654
-
(2011)
European Journal of Immunology
, vol.41
, Issue.12
, pp. 3495-3505
-
-
Yu, C.R.1
Oh, H.M.2
Golestaneh, N.3
Amadi-Obi, A.4
Lee, Y.S.5
Eseonu, A.6
Mahdi, R.M.7
Egwuagu, C.E.8
-
14
-
-
80052235701
-
STAT3 protein promotes T-cell survival and inhibits interleukin-2 production through up-regulation of class O forkhead transcription factors
-
2-s2.0-80052235701 10.1074/jbc.M111.253500
-
Oh H. M., Yu C. R., Golestaneh N., Amadi-Obi A., Lee Y. S., Eseonu A., Mahdi R. M., Egwuagu C. E., STAT3 protein promotes T-cell survival and inhibits interleukin-2 production through up-regulation of class O forkhead transcription factors. The Journal of Biological Chemistry 2011 286 35 30888 30897 2-s2.0-80052235701 10.1074/jbc.M111.253500
-
(2011)
The Journal of Biological Chemistry
, vol.286
, Issue.35
, pp. 30888-30897
-
-
Oh, H.M.1
Yu, C.R.2
Golestaneh, N.3
Amadi-Obi, A.4
Lee, Y.S.5
Eseonu, A.6
Mahdi, R.M.7
Egwuagu, C.E.8
-
15
-
-
79952527975
-
Retinal cells suppress intraocular inflammation (uveitis) through production of interleukin-27 and interleukin-10
-
2-s2.0-79952527975 10.1111/j.1365-2567.2010.03379.x
-
Lee Y. S., Amadi-Obi A., Yu C. R., Egwuagu C. E., Retinal cells suppress intraocular inflammation (uveitis) through production of interleukin-27 and interleukin-10. Immunology 2011 132 4 492 502 2-s2.0-79952527975 10.1111/j.1365-2567.2010.03379.x
-
(2011)
Immunology
, vol.132
, Issue.4
, pp. 492-502
-
-
Lee, Y.S.1
Amadi-Obi, A.2
Yu, C.R.3
Egwuagu, C.E.4
-
16
-
-
80051873375
-
+ T cells: Foot soldiers of the immune system
-
2-s2.0-80051873375 10.1016/j.immuni.2011.07.010
-
+ T cells: foot soldiers of the immune system. Immunity 2011 35 2 161 168 2-s2.0-80051873375 10.1016/j.immuni.2011.07.010
-
(2011)
Immunity
, vol.35
, Issue.2
, pp. 161-168
-
-
Zhang, N.1
Bevan, M.J.2
-
17
-
-
79751529368
-
Alternative memory in the CD8 T cell lineage
-
2-s2.0-79751529368 10.1016/j.it.2010.12.004
-
Lee Y. J., Jameson S. C., Hogquist K. A., Alternative memory in the CD8 T cell lineage. Trends in Immunology 2011 32 2 50 56 2-s2.0-79751529368 10.1016/j.it.2010.12.004
-
(2011)
Trends in Immunology
, vol.32
, Issue.2
, pp. 50-56
-
-
Lee, Y.J.1
Jameson, S.C.2
Hogquist, K.A.3
-
18
-
-
77949423735
-
Regulating functional cell fates in CD8 T cells
-
2-s2.0-77949423735 10.1007/s12026-009-8130-9
-
Shrikant P. A., Rao R., Li Q., Kesterson J., Eppolito C., Mischo A., Singhal P., Regulating functional cell fates in CD8 T cells. Immunologic Research 2009 46 1-3 12 22 2-s2.0-77949423735 10.1007/s12026-009-8130-9
-
(2009)
Immunologic Research
, vol.46
, Issue.1-3
, pp. 12-22
-
-
Shrikant, P.A.1
Rao, R.2
Li, Q.3
Kesterson, J.4
Eppolito, C.5
Mischo, A.6
Singhal, P.7
-
19
-
-
0031128434
-
Functions of CD8 T-cell subsets secreting different cytokine patterns
-
DOI 10.1006/smim.1997.0065
-
Mosmann T. R., Li L., Sad S., Functions of CD8 T-cell subsets secreting different cytokine patterns. Seminars in Immunology 1997 9 2 87 92 2-s2.0-0031128434 10.1006/smim.1997.0065 (Pubitemid 27281471)
-
(1997)
Seminars in Immunology
, vol.9
, Issue.2
, pp. 87-92
-
-
Mosmann, T.R.1
Li, L.2
Sad, S.3
-
20
-
-
34247224342
-
Regulation of lymphocyte development by Notch signaling
-
DOI 10.1038/ni1453, PII NI1453
-
Tanigaki K., Honjo T., Regulation of lymphocyte development by Notch signaling. Nature Immunology 2007 8 5 451 456 2-s2.0-34247224342 10.1038/ni1453 (Pubitemid 46605909)
-
(2007)
Nature Immunology
, vol.8
, Issue.5
, pp. 451-456
-
-
Tanigaki, K.1
Honjo, T.2
-
21
-
-
2442522357
-
Regulation of αβ/γδ T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling
-
DOI 10.1016/S1074-7613(04)00109-8, PII S1074761304001098
-
Tanigaki K., Tsuji M., Yamamoto N., Han H., Tsukada J., Inoue H., Kubo M., Honjo T., Regulation of α β / γ δ T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling. Immunity 2004 20 5 611 622 2-s2.0-2442522357 10.1016/S1074-7613(04)00109-8 (Pubitemid 38638130)
-
(2004)
Immunity
, vol.20
, Issue.5
, pp. 611-622
-
-
Tanigaki, K.1
Tsuji, M.2
Yamamoto, N.3
Han, H.4
Tsukada, J.5
Inoue, H.6
Kubo, M.7
Honjo, T.8
-
22
-
-
77953293952
-
Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis
-
2-s2.0-77953293952 10.1016/j.immuni.2010.05.003
-
Durant L., Watford W. T., Ramos H. L., Laurence A., Vahedi G., Wei L., Takahashi H., Sun H.-W., Kanno Y., Powrie F., O'Shea J. J., Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis. Immunity 2010 32 5 605 615 2-s2.0-77953293952 10.1016/j.immuni. 2010.05.003
-
(2010)
Immunity
, vol.32
, Issue.5
, pp. 605-615
-
-
Durant, L.1
Watford, W.T.2
Ramos, H.L.3
Laurence, A.4
Vahedi, G.5
Wei, L.6
Takahashi, H.7
Sun, H.-W.8
Kanno, Y.9
Powrie, F.10
O'Shea, J.J.11
-
23
-
-
34548125310
-
H-17 differentiation: Of mice and men
-
DOI 10.1038/ni0907-903, PII NI0907-903
-
Laurence A., O'Shea J. J., TH-17 differentiation: of mice and men. Nature Immunology 2007 8 9 903 905 2-s2.0-34548125310 10.1038/ni0907-903 (Pubitemid 47300001)
-
(2007)
Nature Immunology
, vol.8
, Issue.9
, pp. 903-905
-
-
Laurence, A.1
O'Shea, J.J.2
-
24
-
-
33947162110
-
Interleukin-2 Signaling via STAT5 Constrains T Helper 17 Cell Generation
-
DOI 10.1016/j.immuni.2007.02.009, PII S1074761307001768
-
Laurence A., Tato C. M., Davidson T. S., Kanno Y., Chen Z., Yao Z., Blank R., Meylan F., Siegel R., Hennighausen L., Shevach E. M., O'Shea J., Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation. Immunity 2007 26 3 371 381 2-s2.0-33947162110 10.1016/j.immuni.2007.02.009 (Pubitemid 46413906)
-
(2007)
Immunity
, vol.26
, Issue.3
, pp. 371-381
-
-
Laurence, A.1
Tato, C.M.2
Davidson, T.S.3
Kanno, Y.4
Chen, Z.5
Yao, Z.6
Blank, RebeccaB.7
Meylan, F.8
Siegel, R.9
Hennighausen, L.10
Shevach, E.M.11
O'Shea, JohnJ.12
-
25
-
-
60749107176
-
The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo
-
2-s2.0-60749107176 10.1038/ni.1698
-
McGeachy M. J., Chen Y., Tato C. M., Laurence A., Joyce-Shaikh B., Blumenschein W. M., McClanahan T. K., O'Shea J. J., Cua D. J., The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo. Nature Immunology 2009 10 3 314 324 2-s2.0-60749107176 10.1038/ni.1698
-
(2009)
Nature Immunology
, vol.10
, Issue.3
, pp. 314-324
-
-
McGeachy, M.J.1
Chen, Y.2
Tato, C.M.3
Laurence, A.4
Joyce-Shaikh, B.5
Blumenschein, W.M.6
McClanahan, T.K.7
O'Shea, J.J.8
Cua, D.J.9
-
27
-
-
48149096869
-
+ T cells in patients with metastatic melanoma and renal cell carcinoma
-
2-s2.0-48149096869 10.1007/s00262-008-0479-4
-
+ T cells in patients with metastatic melanoma and renal cell carcinoma. Cancer Immunology, Immunotherapy 2008 57 10 1439 1449 2-s2.0-48149096869 10.1007/s00262-008-0479-4
-
(2008)
Cancer Immunology, Immunotherapy
, vol.57
, Issue.10
, pp. 1439-1449
-
-
Frederiksen, K.S.1
Lundsgaard, D.2
Freeman, J.A.3
Hughes, S.D.4
Holm, T.L.5
Skrumsager, B.K.6
Petri, A.7
Hansen, L.T.8
McArthur, G.A.9
Davis, I.D.10
Skak, K.11
-
29
-
-
24644513769
-
Increased expression of the NK cell receptor KLRG1 by virus-specific CD8 T cells during persistent antigen stimulation
-
DOI 10.1128/JVI.79.18.12112-12116.2005
-
Thimme R., Appay V., Koschella M., Panther E., Roth E., Hislop A. D., Rickinson A. B., Rowland-Jones S. L., Blum H. E., Pircher H., Increased expression of the NK cell receptor KLRG1 by virus-specific CD8 T cells during persistent antigen stimulation. Journal of Virology 2005 79 18 12112 12116 2-s2.0-24644513769 10.1128/JVI.79.18.12112-12116.2005 (Pubitemid 41279330)
-
(2005)
Journal of Virology
, vol.79
, Issue.18
, pp. 12112-12116
-
-
Thimme, R.1
Appay, V.2
Koschella, M.3
Panther, E.4
Roth, E.5
Hislop, A.D.6
Rickinson, A.B.7
Rowland-Jones, S.L.8
Blum, H.E.9
Pircher, H.10
-
30
-
-
34250005444
-
H17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1
-
DOI 10.1038/nm1585, PII NM1585
-
Amadi-Obi A., Yu C. R., Liu X., Mahdi R. M., Clarke G. L., Nussenblatt R. B., Gery I., Lee Y. S., Egwuagu C. E., T(H)17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1. Nature Medicine 2007 13 6 711 718 2-s2.0-34250005444 10.1038/nm1585 (Pubitemid 46889754)
-
(2007)
Nature Medicine
, vol.13
, Issue.6
, pp. 711-718
-
-
Amadi-Obi, A.1
Yu, C.-R.2
Liu, X.3
Mahdi, R.M.4
Clarke, G.L.5
Nussenblatt, R.B.6
Gery, I.7
Lee, Y.S.8
Egwuagu, C.E.9
-
32
-
-
33748745741
-
Ocular autoimmunity: The price of privilege?
-
DOI 10.1111/j.1600-065X.2006.00439.x
-
Caspi R. R., Ocular autoimmunity: the price of privilege? Immunological Reviews 2006 213 1 23 35 2-s2.0-33748745741 10.1111/j.1600-065X.2006.00439.x (Pubitemid 44401491)
-
(2006)
Immunological Reviews
, vol.213
, Issue.1
, pp. 23-35
-
-
Caspi, R.R.1
-
33
-
-
84855368621
-
Therapeutic targeting of STAT3 (signal transducers and activators of transcription 3) pathway inhibits experimental autoimmune uveitis
-
2-s2.0-84855368621 10.1371/journal.pone.0029742 e29742
-
Yu C. R., Lee Y. S., Mahdi R. M., Surendran N., Egwuagu C. E., Therapeutic targeting of STAT3 (signal transducers and activators of transcription 3) pathway inhibits experimental autoimmune uveitis. PLoS ONE 2012 7 1 2-s2.0-84855368621 10.1371/journal.pone.0029742 e29742
-
(2012)
PLoS ONE
, vol.7
, Issue.1
-
-
Yu, C.R.1
Lee, Y.S.2
Mahdi, R.M.3
Surendran, N.4
Egwuagu, C.E.5
|