-
1
-
-
0034641568
-
Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): Prospective observational study
-
Stratton IM, Adler AI, Neil HA, et al. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ 2000;321:405-12 (Pubitemid 30609442)
-
(2000)
British Medical Journal
, vol.321
, Issue.7258
, pp. 405-412
-
-
Stratton, I.M.1
Adler, A.I.2
Neil, H.A.W.3
Matthews, D.R.4
Manley, S.E.5
Cull, C.A.6
Hadden, D.7
Turner, R.C.8
Holman, R.R.9
-
2
-
-
0034844049
-
Mortality and causes of death in the WHO multinational study of vascular disease in diabetes
-
Morrish NJ, Wang SL, Stevens LK, et al. Mortality and causes of death in the WHO Multinational Study of Vascular Disease in Diabetes. Diabetologia 2001;44(Suppl 2):S14-21 (Pubitemid 32844108)
-
(2001)
Diabetologia
, vol.44
, Issue.SUPPL. 2
-
-
Morrish, N.J.1
Wang, S.-L.2
Stevens, L.K.3
Fuller, J.H.4
Keen, H.5
Lee, E.T.6
Lu, M.7
Bennett, P.H.8
-
3
-
-
38149118219
-
Secondary prevention of cardiovascular disease in type 2 diabetes and prediabetes: A cardiologist's perspective
-
Cubbon R, Kahn M, Kearney MT. Secondary prevention of cardiovascular disease in type 2 diabetes and prediabetes: a cardiologist's perspective. Int J Clin Pract 2008;62:287-99
-
(2008)
Int J Clin Pract
, vol.62
, pp. 287-299
-
-
Cubbon, R.1
Kahn, M.2
Kearney, M.T.3
-
4
-
-
0036887209
-
Economic considerations in treating patients with type 2 diabetes mellitus
-
White JR. Economic considerations in treating patients with type 2 diabetes mellitus. Am J Health Syst Pharm 2002;59(Suppl 9):S14-17
-
(2002)
Am J Health Syst Pharm
, vol.59
, Issue.9 SUPPL.
-
-
White, J.R.1
-
5
-
-
80455176654
-
Epidemiology and economic impact of obesity and type 2 diabetes
-
vii
-
Shamseddeen H, Getty JZ, Hamdallah IN, Ali MR. Epidemiology and economic impact of obesity and type 2 diabetes. Surg Clin North Am 2011;91:1163-72, vii
-
(2011)
Surg Clin North Am
, vol.91
, pp. 1163-1172
-
-
Shamseddeen, H.1
Getty, J.Z.2
Hamdallah, I.N.3
Ali, M.R.4
-
6
-
-
84876308987
-
Reducing cardiovascular disease risk in type 2 diabetes: Is the focus on glycaemia warranted
-
Fergusson LD, Sattar N. Reducing cardiovascular disease risk in type 2 diabetes: is the focus on glycaemia warranted Diabetes Obes Metab 2012;15:387-91
-
(2012)
Diabetes Obes Metab
, vol.15
, pp. 387-391
-
-
Fergusson, L.D.1
Sattar, N.2
-
7
-
-
84864285795
-
Management of hyperglycaemia in type 2 diabetes: A patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
-
Inzucchi SE, Bergenstal RM, Buse JB, et al. Management of hyperglycaemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetologia 2012;55:1577-96
-
(2012)
Diabetologia
, vol.55
, pp. 1577-1596
-
-
Inzucchi, S.E.1
Bergenstal, R.M.2
Buse, J.B.3
-
8
-
-
84859440269
-
Weight changes and their predictors amongst 11 140 patients with type 2 diabetes in the ADVANCE trial
-
van Dieren S, Czernichow S, Chalmers J, et al. Weight changes and their predictors amongst 11 140 patients with type 2 diabetes in the ADVANCE trial. Diabetes Obes Metab 2012;14:464-9
-
(2012)
Diabetes Obes Metab
, vol.14
, pp. 464-469
-
-
Van Dieren, S.1
Czernichow, S.2
Chalmers, J.3
-
9
-
-
75549091061
-
Incretin-based therapies: Viewpoints on the way to consensus
-
Nauck MA, Vilsboll T, Gallwitz B, et al. Incretin-based therapies: viewpoints on the way to consensus. Diabetes Care 2009;32(Suppl 2):S223-31
-
(2009)
Diabetes Care
, vol.32
, Issue.2 SUPPL.
-
-
Nauck, M.A.1
Vilsboll, T.2
Gallwitz, B.3
-
10
-
-
33846006173
-
The incretin system: Glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
-
DOI 10.1016/S0140-6736(06)69705-5, PII S0140673606697055
-
Drucker DJ, Nauck MA. The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. Lancet 2006;368:1696-705 (Pubitemid 46048557)
-
(2006)
Lancet
, vol.368
, Issue.9548
, pp. 1696-1705
-
-
Drucker, D.J.1
Nauck, M.A.2
-
11
-
-
84859003663
-
Effects of glucagon-like peptide- 1 receptor agonists on weight loss: Systematic review and meta-analyses of randomised controlled trials
-
Vilsboll T, Christensen M, Junker AE, et al. Effects of glucagon-like peptide- 1 receptor agonists on weight loss: systematic review and meta-analyses of randomised controlled trials. BMJ 2012;344:d7771
-
(2012)
BMJ
, vol.344
-
-
Vilsboll, T.1
Christensen, M.2
Junker, A.E.3
-
12
-
-
78650753885
-
Incretin-based therapies for type 2 diabetes mellitus: Properties, functions, and clinical implications
-
Nauck MA. Incretin-based therapies for type 2 diabetes mellitus: properties, functions, and clinical implications. Am J Med 2011;124:S3-18
-
(2011)
Am J Med
, vol.124
-
-
Nauck, M.A.1
-
13
-
-
0035405821
-
Glucagon-Like Peptide-1 and Exendin-4 Stimulate β-Cell Neogenesis in Streptozotocin-Treated Newborn Rats Resulting in Persistently Improved Glucose Homeostasis at Adult Age
-
Tourrel C, Bailbe D, Meile MJ, et al. Glucagon-like peptide-1 and exendin-4 stimulate beta-cell neogenesis in streptozotocin-treated newborn rats resulting in persistently improved glucose homeostasis at adult age. Diabetes 2001;50:1562-70 (Pubitemid 33639596)
-
(2001)
Diabetes
, vol.50
, Issue.7
, pp. 1562-1570
-
-
Tourrel, C.1
Bailbe, D.2
Meile, M.-J.3
Kergoat, M.4
Portha, B.5
-
14
-
-
0036828227
-
Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats
-
DOI 10.1210/en.2002-220405
-
Farilla L, Hui H, Bertolotto C, et al. Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats. Endocrinology 2002;143:4397-408 (Pubitemid 35239574)
-
(2002)
Endocrinology
, vol.143
, Issue.11
, pp. 4397-4408
-
-
Farilla, L.1
Hongxiang, H.2
Bertolotto, C.3
Kang, E.4
Bulotta, A.5
Mario, U.D.I.6
Perfetti, R.7
-
15
-
-
1442311383
-
Effects of Glucagon-Like Peptide-1 in Patients with Acute Myocardial Infarction and Left Ventricular Dysfunction after Successful Reperfusion
-
DOI 10.1161/01.CIR.0000120505.91348.58
-
Nikolaidis LA, Mankad S, Sokos GG, et al. Effects of glucagon-like peptide- 1 in patients with acute myocardial infarction and left ventricular dysfunction after successful reperfusion. Circulation 2004;109:962-5 (Pubitemid 38282847)
-
(2004)
Circulation
, vol.109
, Issue.8
, pp. 962-965
-
-
Nikolaidis, L.A.1
Mankad, S.2
Sokos, G.G.3
Miske, G.4
Shah, A.5
Elahi, D.6
Shannon, R.P.7
-
16
-
-
0002300343
-
Glucagon-like peptide-1: A potent regulator of food intake in humans
-
Gutzwiller JP, Goke B, Drewe J, et al. Glucagon-like peptide-1: a potent regulator of food intake in humans. Gut 1999;44:81-6 (Pubitemid 29143284)
-
(1999)
Gut
, vol.44
, Issue.1
, pp. 81-86
-
-
Gutzwiller, J.-P.1
Goke, B.2
Drewe, J.3
Hildebrand, P.4
Ketterer, S.5
Handschin, D.6
Winterhalder, R.7
Conen, D.8
Beglinger, C.9
-
17
-
-
84865130603
-
Addition of liraglutide in patients with type 2 diabetes well controlled on metformin monotherapy improves several markers of vascular function
-
Forst T, Michelson G, Ratter F, et al. Addition of liraglutide in patients with type 2 diabetes well controlled on metformin monotherapy improves several markers of vascular function. Diabet Med 2012;29:1115-18
-
(2012)
Diabet Med
, vol.29
, pp. 1115-1118
-
-
Forst, T.1
Michelson, G.2
Ratter, F.3
-
18
-
-
79953826349
-
Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes
-
Kodera R, Shikata K, Kataoka HU, et al. Glucagon-like peptide-1 receptor agonist ameliorates renal injury through its anti-inflammatory action without lowering blood glucose level in a rat model of type 1 diabetes. Diabetologia 2011;54:965-78
-
(2011)
Diabetologia
, vol.54
, pp. 965-978
-
-
Kodera, R.1
Shikata, K.2
Kataoka, H.U.3
-
19
-
-
80054708816
-
Glucagon-like peptide-1 (GLP-1) receptor agonists, obesity and psoriasis: Diabetes meets dermatology
-
Drucker DJ, Rosen CF. Glucagon-like peptide-1 (GLP-1) receptor agonists, obesity and psoriasis: diabetes meets dermatology. Diabetologia 2011;54:2741-4
-
(2011)
Diabetologia
, vol.54
, pp. 2741-2744
-
-
Drucker, D.J.1
Rosen, C.F.2
-
20
-
-
84870054636
-
GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus
-
Meier JJ. GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus. Nat Rev Endocrinol 2012;8:728-42
-
(2012)
Nat Rev Endocrinol
, vol.8
, pp. 728-742
-
-
Meier, J.J.1
-
22
-
-
44949250352
-
Targeting plasma glucose: Preprandial versus postprandial
-
Schrot RJ. Targeting plasma glucose: preprandial versus postprandial. Clin Diabetes 2004;22:169-72
-
(2004)
Clin Diabetes
, vol.22
, pp. 169-172
-
-
Schrot, R.J.1
-
23
-
-
0038497464
-
Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes
-
DOI 10.1210/jc.2002-021545
-
Kolterman OG, Buse JB, Fineman MS, et al. Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes. J Clin Endocrinol Metab 2003;88:3082-9 (Pubitemid 36877476)
-
(2003)
Journal of Clinical Endocrinology and Metabolism
, vol.88
, Issue.7
, pp. 3082-3089
-
-
Kolterman, O.G.1
Buse, J.B.2
Fineman, M.S.3
Gaines, E.4
Heintz, S.5
Bicsak, T.A.6
Taylor, K.7
Kim, D.8
Aisporna, M.9
Wang, Y.10
Baron, A.D.11
-
24
-
-
0026648961
-
Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas
-
Eng J, Kleinman WA, Singh L, et al. Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas. J Biol Chem 1992;267:7402-5
-
(1992)
J Biol Chem
, vol.267
, pp. 7402-7405
-
-
Eng, J.1
Kleinman, W.A.2
Singh, L.3
-
25
-
-
0034108646
-
Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration
-
DOI 10.1021/jm9909645
-
Knudsen LB, Nielsen PF, Huusfeldt PO, et al. Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration. J Med Chem 2000;43:1664-9 (Pubitemid 30304999)
-
(2000)
Journal of Medicinal Chemistry
, vol.43
, Issue.9
, pp. 1664-1669
-
-
Knudsen, L.B.1
Nielsen, P.F.2
Huusfeldt, P.O.3
Johansen, N.L.4
Madsen, K.5
Pedersen, F.Z.6
Thogersen, H.7
Wilken, M.8
Agerso, H.9
-
27
-
-
84866545755
-
Lixisenatide: Evidence for its potential use in the treatment of type 2 diabetes
-
Barnett AH. Lixisenatide: evidence for its potential use in the treatment of type 2 diabetes. Core Evid 2011;6:67-79
-
(2011)
Core Evid
, vol.6
, pp. 67-79
-
-
Barnett, A.H.1
-
28
-
-
0142179159
-
Glucagon-Like Peptide 1 Receptor Agonist ZP10A Increases Insulin mRNA Expression and Prevents Diabetic Progression in db/db Mice
-
DOI 10.1124/jpet.103.051987
-
Thorkildsen C, Neve S, Larsen BD, et al. Glucagon-like peptide 1 receptor agonist ZP10A increases insulin mRNA expression and prevents diabetic progression in db/db mice. J Pharmacol Exp Ther 2003;307:490-6 (Pubitemid 37310661)
-
(2003)
Journal of Pharmacology and Experimental Therapeutics
, vol.307
, Issue.2
, pp. 490-496
-
-
Thorkildsen, C.1
Neve, S.2
Larsen, B.D.3
Meier, E.4
Petersen, J.S.5
-
29
-
-
77955847376
-
Pharmacological profile of lixisenatide: A new GLP-1 receptor agonist for the treatment of type 2 diabetes
-
Werner U, Haschke G, Herling AW, Kramer W. Pharmacological profile of lixisenatide: a new GLP-1 receptor agonist for the treatment of type 2 diabetes. Regul Pept 2010;164:58-64
-
(2010)
Regul Pept
, vol.164
, pp. 58-64
-
-
Werner, U.1
Haschke, G.2
Herling, A.W.3
Kramer, W.4
-
30
-
-
84555171818
-
Pharmacokinetics and safety of the GLP-1 agonist AVE0010 in patient with renal impairment
-
abstract 557-P
-
Liu Y-H, Ruus P. Pharmacokinetics and safety of the GLP-1 agonist AVE0010 in patient with renal impairment. Ann Meet Am Diabetes Assoc 2009;69:abstract 557-P
-
(2009)
Ann Meet Am Diabetes Assoc
, vol.69
-
-
Liu, Y.-H.1
Ruus, P.2
-
31
-
-
58349104177
-
Pharmacokinetics and pharmacodynamics of GLP-1 agonist AVE0010 in type 2 diabetes patients
-
abstract 520-P
-
Distiller L, Ruus PE. Pharmacokinetics and pharmacodynamics of GLP-1 agonist AVE0010 in type 2 diabetes patients. Ann Meet Am Diabetes Assoc 2008;68:abstract 520-P
-
(2008)
Ann Meet Am Diabetes Assoc
, vol.68
-
-
Distiller, L.1
Ruus, P.E.2
-
32
-
-
84861765116
-
Efficacy and safety of the once-daily GLP-1 receptor agonist lixisenatide in monotherapy: A randomized, double-blind, placebo-controlled trial in patients with type 2 diabetes (GetGoal-Mono)
-
Fonseca VA, Alvarado-Ruiz R, Raccah D, et al. Efficacy and safety of the once-daily GLP-1 receptor agonist lixisenatide in monotherapy: a randomized, double-blind, placebo-controlled trial in patients with type 2 diabetes (GetGoal-Mono). Diabetes Care 2012;35:1225-31
-
(2012)
Diabetes Care
, vol.35
, pp. 1225-1231
-
-
Fonseca, V.A.1
Alvarado-Ruiz, R.2
Raccah, D.3
-
33
-
-
84878358313
-
Efficacy and safety of lixisenatide once daily morning or evening injections in type 2 diabetes inadequately controlled on metformin (GetGoal-M)
-
Ahren B, Dimas A, Miossec P, et al. Efficacy and safety of lixisenatide once daily morning or evening injections in type 2 diabetes inadequately controlled on metformin (GetGoal-M). Diabetes Care 2013;36:2543-50
-
(2013)
Diabetes Care
, vol.36
, pp. 2543-2550
-
-
Ahren, B.1
Dimas, A.2
Miossec, P.3
-
34
-
-
84885331631
-
Efficacy and safety of lixisenatide once daily versus placebo in type 2 diabetes insufficiently controlled on pioglitazone (GetGoal-P)
-
Epub ahead of print
-
Pinget M, Goldenberg R, Niemoeller E, et al. Efficacy and safety of lixisenatide once daily versus placebo in type 2 diabetes insufficiently controlled on pioglitazone (GetGoal-P). Diabetes Obes Metab 2013; Epub ahead of print
-
(2013)
Diabetes Obes Metab
-
-
Pinget, M.1
Goldenberg, R.2
Niemoeller, E.3
-
35
-
-
84865979163
-
Investigators EG-LAS, Randomized, double-blind, placebo-controlled trial of the once-daily GLP-1 receptor agonist lixisenatide in Asian patients with type 2 diabetes insufficiently controlled on basal insulin with or without a sulfonylurea (GetGoal- L-Asia)
-
Seino Y, Min KW, Niemoeller E, Takami A; Investigators EG-LAS. Randomized, double-blind, placebo-controlled trial of the once-daily GLP-1 receptor agonist lixisenatide in Asian patients with type 2 diabetes insufficiently controlled on basal insulin with or without a sulfonylurea (GetGoal- L-Asia). Diabetes Obes Metab 2012;14:910-17
-
(2012)
Diabetes Obes Metab
, vol.14
, pp. 910-917
-
-
Seino, Y.1
Min, K.W.2
Niemoeller, E.3
Takami, A.4
-
36
-
-
84878603672
-
Adding once-daily lixisenatide for type 2 diabetes inadequately controlled with newly initiated and continuously titrated basal insulin glargine: A 24-week, randomized, placebo-controlled study (GetGoal-Duo 1)
-
Riddle MC, Forst T, Aronson R, et al. Adding once-daily lixisenatide for type 2 diabetes inadequately controlled with newly initiated and continuously titrated basal insulin glargine: a 24-week, randomized, placebo-controlled study (GetGoal-Duo 1). Diabetes Care 2013;36:2497-503
-
(2013)
Diabetes Care
, vol.36
, pp. 2497-2503
-
-
Riddle, M.C.1
Forst, T.2
Aronson, R.3
-
37
-
-
84878592117
-
Adding once-daily lixisenatide for type 2 diabetes inadequately controlled by established basal insulin: A 24-week, randomized, placebo-controlled comparison (GetGoal-L)
-
Riddle MC, Aronson R, Home P, et al. Adding once-daily lixisenatide for type 2 diabetes inadequately controlled by established basal insulin: a 24-week, randomized, placebo-controlled comparison (GetGoal-L). Diabetes Care 2013;36:2489-96
-
(2013)
Diabetes Care
, vol.36
, pp. 2489-2496
-
-
Riddle, M.C.1
Aronson, R.2
Home, P.3
-
38
-
-
84883324640
-
Efficacy and safety of lixisenatide once daily versus exenatide twice daily in type 2 diabetes inadequately controlled on metformin: A 24-week, randomized, open-label, active-controlled study (GetGoal-X)
-
Epub ahead of print
-
Rosenstock J, Raccah D, Koranyi L, et al. Efficacy and safety of lixisenatide once daily versus exenatide twice daily in type 2 diabetes inadequately controlled on metformin: a 24-week, randomized, open-label, active-controlled study (GetGoal-X). Diabetes Care 2013; Epub ahead of print
-
(2013)
Diabetes Care
-
-
Rosenstock, J.1
Raccah, D.2
Koranyi, L.3
-
39
-
-
84878863716
-
Pharmacodynamic characteristics of lixisenatide once daily versus liraglutide once daily in patients with type 2 diabetes insufficiently controlled on metformin
-
Kapitza C, Forst T, Coester HV, et al. Pharmacodynamic characteristics of lixisenatide once daily versus liraglutide once daily in patients with type 2 diabetes insufficiently controlled on metformin. Diabetes Obes Metab 2013;15:642-9
-
(2013)
Diabetes Obes Metab
, vol.15
, pp. 642-649
-
-
Kapitza, C.1
Forst, T.2
Coester, H.V.3
-
40
-
-
84878549237
-
Effects of lixisenatide once daily on gastric emptying in type 2 diabetes - Relationship to postprandial glycemia
-
Lorenz M, Pfeiffer C, Steinsträer A, et al. Effects of lixisenatide once daily on gastric emptying in type 2 diabetes - Relationship to postprandial glycemia. Regul Pept 2013;185C:1-8
-
(2013)
Regul Pept
, vol.185 C
, pp. 1-8
-
-
Lorenz, M.1
Pfeiffer, C.2
Steinsträer, A.3
-
41
-
-
84892556531
-
Efficacy and safety of lixisenatide once-daily versus placebo in patients with type 2 diabetes insufficiently controlled on metformin (GetGoal-F1)
-
In press
-
Bolli G, Munteanu M, Dotsenko S, et al. Efficacy and safety of lixisenatide once-daily versus placebo in patients with type 2 diabetes insufficiently controlled on metformin (GetGoal-F1). Diabetic Medicine 2013; In press
-
(2013)
Diabetic Medicine
-
-
Bolli, G.1
Munteanu, M.2
Dotsenko, S.3
-
42
-
-
84878622377
-
Efficacy and safety of lixisenatide once daily versus placebo in patients with T2DM insufficiently controlled on sulfonylurea + metformin (GetGoal-S) [abstract 785]
-
Ratner R, Hanefeld M, Shamanna P, et al. Efficacy and safety of lixisenatide once daily versus placebo in patients with T2DM insufficiently controlled on sulfonylurea + metformin (GetGoal-S) [abstract 785]. Diabetologia 2011;54:1-542
-
(2011)
Diabetologia
, vol.54
, pp. 1-542
-
-
Ratner, R.1
Hanefeld, M.2
Shamanna, P.3
-
43
-
-
9644265449
-
Insulin secretion capacity in the development from normal glucose tolerance to type 2 diabetes
-
DOI 10.1016/j.diabres.2003.11.024, PII S0168822704001603
-
Fukushima M, Suzuki H, Seino Y. Insulin secretion capacity in the development from normal glucose tolerance to type 2 diabetes. Diabetes Res Clin Pract 2004;66(Suppl 1):S37-43 (Pubitemid 39572582)
-
(2004)
Diabetes Research and Clinical Practice
, vol.66
, Issue.SUPPL.
-
-
Fukushima, M.1
Suzuki, H.2
Seino, Y.3
-
44
-
-
79953170013
-
Little enhancement of meal-induced glucagonlike peptide 1 secretion in Japanese: Comparison of type 2 diabetes patients and healthy controls
-
Yabe D, Kuroe A, Lee S, et al. Little enhancement of meal-induced glucagonlike peptide 1 secretion in Japanese: comparison of type 2 diabetes patients and healthy controls. J Diabetes Invest 2010;1:56-9
-
(2010)
J Diabetes Invest
, vol.1
, pp. 56-59
-
-
Yabe, D.1
Kuroe, A.2
Lee, S.3
-
45
-
-
84874639175
-
Efficacy and safety of lixisenatide in elderly (65 yr) and very elderly (75 yr) patients with type 2 diabetes: An analysis from the GetGoal phase 3 program
-
8 - 12 June, Philadelphia, PA; 2012
-
Raccah D, Miossec P, Esposito V, et al. Efficacy and safety of lixisenatide in elderly (65 yr) and very elderly (75 yr) patients with type 2 diabetes: an analysis from the GetGoal phase 3 program. Poster 972-P, presented at 72nd Scientific Sessions of the American Diabetes Association; 8 - 12 June 2012; Philadelphia, PA; 2012
-
(2012)
Poster 972-P, Presented at 72nd Scientific Sessions of the American Diabetes Association
-
-
Raccah, D.1
Miossec, P.2
Esposito, V.3
-
46
-
-
43249089631
-
Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways
-
DOI 10.1161/CIRCULATIONAHA.107.739938, PII 0000301720080506000007
-
Ban K, Noyan-Ashraf MH, Hoefer J, et al. Cardioprotective and vasodilatory actions of glucagon-like peptide 1 receptor are mediated through both glucagon-like peptide 1 receptor-dependent and -independent pathways. Circulation 2008;117:2340-50 (Pubitemid 351653542)
-
(2008)
Circulation
, vol.117
, Issue.18
, pp. 2340-2350
-
-
Ban, K.1
Noyan-Ashraf, M.H.2
Hoefer, J.3
Bolz, S.-S.4
Drucker, D.J.5
Husain, M.6
-
47
-
-
77955828386
-
Possible involvement of GLP-1(9- 36) in the regional haemodynamic effects of GLP-1(7-36) in conscious rats
-
Gardiner SM, March JE, Kemp PA, et al. Possible involvement of GLP-1(9- 36) in the regional haemodynamic effects of GLP-1(7-36) in conscious rats. Br J Pharmacol 2010;161:92-102
-
(2010)
Br J Pharmacol
, vol.161
, pp. 92-102
-
-
Gardiner, S.M.1
March, J.E.2
Kemp, P.A.3
-
48
-
-
0033304603
-
The glucagon-like peptides
-
Kieffer TJ, Habener JF. The glucagon-like peptides. Endocr Rev 1999;20:876-913 (Pubitemid 30647076)
-
(1999)
Endocrine Reviews
, vol.20
, Issue.6
, pp. 876-913
-
-
Kieffer, T.J.1
Habener, J.F.2
-
49
-
-
75249100556
-
Insulin-like actions of glucagon-like peptide-1: A dual receptor hypothesis
-
Tomas E, Habener JF. Insulin-like actions of glucagon-like peptide-1: a dual receptor hypothesis. Trends Endocrinol Metab 2010;21:59-67
-
(2010)
Trends Endocrinol Metab
, vol.21
, pp. 59-67
-
-
Tomas, E.1
Habener, J.F.2
-
50
-
-
33845293219
-
Glucagon-Like Peptide-1 Infusion Improves Left Ventricular Ejection Fraction and Functional Status in Patients With Chronic Heart Failure
-
DOI 10.1016/j.cardfail.2006.08.211, PII S1071916406011092
-
Sokos GG, Nikolaidis LA, Mankad S, et al. Glucagon-like peptide-1 infusion improves left ventricular ejection fraction and functional status in patients with chronic heart failure. J Card Fail 2006;12:694-9 (Pubitemid 44881367)
-
(2006)
Journal of Cardiac Failure
, vol.12
, Issue.9
, pp. 694-699
-
-
Sokos, G.G.1
Nikolaidis, L.A.2
Mankad, S.3
Elahi, D.4
Shannon, R.P.5
-
51
-
-
77955573674
-
Efficacy and safety of exenatide once weekly versus sitagliptin or pioglitazone as an adjunct to metformin for treatment of type 2 diabetes (DURATION-2 a randomised trial
-
Bergenstal RM, Wysham C, Macconell L, et al. Efficacy and safety of exenatide once weekly versus sitagliptin or pioglitazone as an adjunct to metformin for treatment of type 2 diabetes (DURATION-2): a randomised trial. Lancet 2010;376:431-9
-
(2010)
Lancet
, vol.376
, pp. 431-439
-
-
Bergenstal, R.M.1
Wysham, C.2
Macconell, L.3
-
52
-
-
50649110233
-
Beneficial effects of once-daily liraglutide, a human glucagon-like peptide-1 analogue, on cardiovascular risk biomarkers in patients with Type 2 diabetes
-
Courreges JP, Vilsboll T, Zdravkovic M, et al. Beneficial effects of once-daily liraglutide, a human glucagon-like peptide-1 analogue, on cardiovascular risk biomarkers in patients with Type 2 diabetes. Diabet Med 2008;25:1129-31
-
(2008)
Diabet Med
, vol.25
, pp. 1129-1131
-
-
Courreges, J.P.1
Vilsboll, T.2
Zdravkovic, M.3
-
53
-
-
84868225851
-
Cardioprotective effect of the GLP-1 receptor agonist lixisenatide on ischemia-reperfusion-induced injury in the isolated rat heart
-
abstract A265
-
Huber J, Janecek E, Meister S, et al. Cardioprotective effect of the GLP-1 receptor agonist lixisenatide on ischemia-reperfusion-induced injury in the isolated rat heart. Diabetes 2011;60:abstract A265
-
(2011)
Diabetes
, vol.60
-
-
Huber, J.1
Janecek, E.2
Meister, S.3
-
54
-
-
84885603449
-
Cardioprotective effect of chronic treatment with lixisenatide in an in vivo rat model of myocardial ischaemia/reperfusion-induced injury
-
1 - 5 October, Berlin, Germany; 2012
-
Wohlfart P, Linz W, Linz D, et al. Cardioprotective effect of chronic treatment with lixisenatide in an in vivo rat model of myocardial ischaemia/reperfusion-induced injury. Presented at the 48th European Association for the Study of Diabetes Annual Meeting; 1 - 5 October 2012; Berlin, Germany; 2012
-
(2012)
Presented at the 48th European Association for the Study of Diabetes Annual Meeting
-
-
Wohlfart, P.1
Linz, W.2
Linz, D.3
-
55
-
-
84873554686
-
Effects of exenatide and liraglutide on heart rate, blood pressure and body weight: Systematic review and meta-analysis
-
Robinson LE, Holt TA, Rees K, et al. Effects of exenatide and liraglutide on heart rate, blood pressure and body weight: systematic review and meta-analysis. BMJ Open 2013;3;e001986
-
(2013)
BMJ Open
, vol.3
-
-
Robinson, L.E.1
Holt, T.A.2
Rees, K.3
-
56
-
-
36148932551
-
Beneficial effects of GLP-1 on endothelial function in humans: Dampening by glyburide but not by glimepiride
-
DOI 10.1152/ajpendo.00373.2007
-
Basu A, Charkoudian N, Schrage W, et al. Beneficial effects of GLP-1 on endothelial function in humans: dampening by glyburide but not by glimepiride. Am J Physiol Endocrinol Metab 2007;293:E1289-95 (Pubitemid 350106596)
-
(2007)
American Journal of Physiology - Endocrinology and Metabolism
, vol.293
, Issue.5
-
-
Basu, A.1
Charkoudian, N.2
Schrage, W.3
Rizza, R.A.4
Basu, R.5
Joyner, M.J.6
-
57
-
-
0035892681
-
Vasorelaxant effect of glucagon-like peptide-(7-36)amide and amylin on the pulmonary circulation of the rat
-
DOI 10.1016/S0167-0115(01)00300-7, PII S0167011501003007
-
Golpon HA, Puechner A, Welte T, et al. Vasorelaxant effect of glucagon-like peptide-(7-36)amide and amylin on the pulmonary circulation of the rat. Regul Pept 2001;102:81-6 (Pubitemid 33135568)
-
(2001)
Regulatory Peptides
, vol.102
, Issue.2-3
, pp. 81-86
-
-
Golpon, H.A.1
Puechner, A.2
Welte, T.3
Wichert, P.V.4
Feddersen, C.O.5
-
58
-
-
0027495779
-
GLP-1 stimulates secretion of macromolecules from airways and relaxes pulmonary artery
-
Richter G, Feddersen O, Wagner U, et al. GLP-1 stimulates secretion of macromolecules from airways and relaxes pulmonary artery. Am J Physiol 1993;265:L374-81
-
(1993)
Am J Physiol
, vol.265
-
-
Richter, G.1
Feddersen, O.2
Wagner, U.3
-
59
-
-
77958052010
-
A glucagon-like peptide-1 (GLP-1) analogue, liraglutide, upregulates nitric oxide production and exerts anti-inflammatory action in endothelial cells
-
Hattori Y, Jojima T, Tomizawa A, et al. A glucagon-like peptide-1 (GLP-1) analogue, liraglutide, upregulates nitric oxide production and exerts anti-inflammatory action in endothelial cells. Diabetologia 2010;53:2256-63
-
(2010)
Diabetologia
, vol.53
, pp. 2256-2263
-
-
Hattori, Y.1
Jojima, T.2
Tomizawa, A.3
-
60
-
-
8544258807
-
Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease
-
DOI 10.1152/ajpendo.00237.2004
-
Nystrom T, Gutniak MK, Zhang Q, et al. Effects of glucagon-like peptide- 1 on endothelial function in type 2 diabetes patients with stable coronary artery disease. Am J Physiol Endocrinol Metab 2004;287:E1209-15 (Pubitemid 39491964)
-
(2004)
American Journal of Physiology - Endocrinology and Metabolism
, vol.287
, Issue.6506
-
-
Nystrom, T.1
Gutniak, M.K.2
Zhang, Q.3
Zhang, F.4
Holst, J.J.5
Ahren, B.6
Sjoholm, A.7
-
61
-
-
67649666737
-
Liraglutide once a day versus exenatide twice a day for type 2 diabetes: A 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6)
-
Buse JB, Rosenstock J, Sesti G, et al. Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6). Lancet 2009;374:39-47
-
(2009)
Lancet
, vol.374
, pp. 39-47
-
-
Buse, J.B.1
Rosenstock, J.2
Sesti, G.3
-
62
-
-
38549162147
-
Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in patients with type 2 diabetes treated for at least 3 years
-
DOI 10.1185/030079907X253870
-
Klonoff DC, Buse JB, Nielsen LL, et al. Exenatide effects on diabetes, obesity, cardiovascular risk factors and hepatic biomarkers in patients with type 2 diabetes treated for at least 3 years. Curr Med Res Opin 2008;24:275-86 (Pubitemid 351160260)
-
(2008)
Current Medical Research and Opinion
, vol.24
, Issue.1
, pp. 275-286
-
-
Klonoff, D.C.1
Buse, J.B.2
Nielsen, L.L.3
Guan, X.4
Bowlus, C.L.5
Holcombe, J.H.6
Wintle, M.E.7
Maggs, D.G.8
-
63
-
-
59149098087
-
The role of incretins in cardiovascular control
-
Mafong DD, Henry RR. The role of incretins in cardiovascular control. Curr Hypertens Rep 2009;11:18-22
-
(2009)
Curr Hypertens Rep
, vol.11
, pp. 18-22
-
-
Mafong, D.D.1
Henry, R.R.2
-
64
-
-
62449129181
-
Liraglutide, a once-daily human GLP-1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with Type 2 diabetes (LEAD-1 SU)
-
Marre M, Shaw J, Brandle M, et al. Liraglutide, a once-daily human GLP-1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with Type 2 diabetes (LEAD-1 SU). Diabet Med 2009;26:268-78
-
(2009)
Diabet Med
, vol.26
, pp. 268-278
-
-
Marre, M.1
Shaw, J.2
Brandle, M.3
-
65
-
-
76749161358
-
Effects of exenatide on systolic blood pressure in subjects with type 2 diabetes
-
Okerson T, Yan P, Stonehouse A, Brodows R. Effects of exenatide on systolic blood pressure in subjects with type 2 diabetes. Am J Hypertens 2010;23:334-9
-
(2010)
Am J Hypertens
, vol.23
, pp. 334-339
-
-
Okerson, T.1
Yan, P.2
Stonehouse, A.3
Brodows, R.4
-
66
-
-
2942668372
-
Glucagon-like peptide 1 induces natriuresis in healthy subjects and in insulin-resistant obese men
-
DOI 10.1210/jc.2003-031403
-
Gutzwiller JP, Tschopp S, Bock A, et al. Glucagon-like peptide 1 induces natriuresis in healthy subjects and ininsulin-resistant obese men. J Clin Endocrinol Metab 2004;89:3055-61 (Pubitemid 38766408)
-
(2004)
Journal of Clinical Endocrinology and Metabolism
, vol.89
, Issue.6
, pp. 3055-3061
-
-
Gutzwiller, J.-P.1
Tschopp, S.2
Bock, A.3
Zehnder, C.E.4
Huber, A.R.5
Kreyenbuehl, M.6
Gutmann, H.7
Drewe, J.8
Henzen, C.9
Goeke, B.10
Beglinger, C.11
-
67
-
-
79959259385
-
Glucagon-like peptide-1 receptor agonists and cardiovascular events: A meta-analysis of randomized clinical trials
-
Monami M, Cremasco F, Lamanna C, et al. Glucagon-like peptide-1 receptor agonists and cardiovascular events: a meta-analysis of randomized clinical trials. Exp Diabetes Res 2011;2011:215764
-
(2011)
Exp Diabetes Res
, vol.2011
, pp. 215764
-
-
Monami, M.1
Cremasco, F.2
Lamanna, C.3
-
69
-
-
84885667109
-
The GLP-1 receptor agonist AVE0010 abolishes OGTT-induced blood glucose excursion in healthy, normoglycemic dog without risk of hypoglycaemia [abstract 0486-P]
-
22 - 26 June, Chicago, IL
-
Werner U, Gerlach M, Hofmann M, Herling AW. The GLP-1 receptor agonist AVE0010 abolishes OGTT-induced blood glucose excursion in healthy, normoglycemic dog without risk of hypoglycaemia [abstract 0486-P]. Poster presented at the 67th Scientific Session of the American Diabetes Association; 22 - 26 June 2007; Chicago, IL
-
(2007)
Poster Presented at the 67th Scientific Session of the American Diabetes Association
-
-
Werner, U.1
Gerlach, M.2
Hofmann, M.3
Herling, A.W.4
-
70
-
-
79959404178
-
Rapid tachyphylaxis of the glucagon-like peptide 1-induced deceleration of gastric emptying in humans
-
Nauck MA, Kemmeries G, Holst JJ, Meier JJ. Rapid tachyphylaxis of the glucagon-like peptide 1-induced deceleration of gastric emptying in humans. Diabetes 2011;60:1561-5
-
(2011)
Diabetes
, vol.60
, pp. 1561-1565
-
-
Nauck, M.A.1
Kemmeries, G.2
Holst, J.J.3
Meier, J.J.4
-
71
-
-
15944414254
-
Proinsulin concentration is an independent predictor of all-cause and cardiovascular mortality: An 11-year follow-up of the Hoorn study
-
DOI 10.2337/diacare.28.4.860
-
Alssema M, Dekker JM, Nijpels G, et al. Proinsulin concentration is an independent predictor of all-cause and cardiovascular mortality: an 11-year follow-up of the Hoorn Study. Diabetes Care 2005;28:860-5 (Pubitemid 40434486)
-
(2005)
Diabetes Care
, vol.28
, Issue.4
, pp. 860-865
-
-
Alssema, M.1
Dekker, J.M.2
Nijpels, G.3
Stehouwer, C.D.A.4
Bouter, L.M.5
Heine, R.J.6
-
72
-
-
20044368678
-
Insulin sensitivity, proinsulin and insulin as predictors of coronary heart disease. A population-based 10-year, follow-up study in 70-year old men using the euglycaemic insulin clamp
-
DOI 10.1007/s00125-005-1711-9
-
Zethelius B, Lithell H, Hales CN, Berne C. Insulin sensitivity, proinsulin and insulin as predictors of coronary heart disease. A population-based 10-year, follow-up study in 70-year old men using the euglycaemic insulin clamp. Diabetologia 2005;48:862-7 (Pubitemid 40767978)
-
(2005)
Diabetologia
, vol.48
, Issue.5
, pp. 862-867
-
-
Zethelius, B.1
Lithell, H.2
Hales, C.N.3
Berne, C.4
-
73
-
-
0037133567
-
Sex differences in the association between proinsulin and intact insulin with coronary heart disease in nondiabetic older adults: The Rancho Bernardo study
-
DOI 10.1161/hc1102.105565
-
Oh JY, Barrett-Connor E, Wedick NM. Sex differences in the association between proinsulin and intact insulin with coronary heart disease in nondiabetic older adults: the Rancho Bernardo Study. Circulation 2002;105:1311-16 (Pubitemid 34260421)
-
(2002)
Circulation
, vol.105
, Issue.11
, pp. 1311-1316
-
-
Oh, J.-Y.1
Barrett-Connor, E.2
Wedick, N.M.3
-
74
-
-
57249094220
-
Insulin sensitivity measured by the euglycaemic insulin clamp and proinsulin levels as predictors of stroke in elderly men
-
Wiberg B, Sundstrom J, Zethelius B, Lind L. Insulin sensitivity measured by the euglycaemic insulin clamp and proinsulin levels as predictors of stroke in elderly men. Diabetologia 2009;52:90-6
-
(2009)
Diabetologia
, vol.52
, pp. 90-96
-
-
Wiberg, B.1
Sundstrom, J.2
Zethelius, B.3
Lind, L.4
-
75
-
-
0041760985
-
Impaired insulin sensitivity is an independent predictor of common carotid intima-media thickness in a population sample of elderly men
-
DOI 10.1016/S0021-9150(03)00283-1
-
Wohlin M, Sundstrom J, Arnlov J, et al. Impaired insulin sensitivity is an independent predictor of common carotid intima-media thickness in a population sample of elderly men. Atherosclerosis 2003;170:181-5 (Pubitemid 37083578)
-
(2003)
Atherosclerosis
, vol.170
, Issue.1
, pp. 181-185
-
-
Wohlin, M.1
Sundstrom, J.2
Arnlov, J.3
Andren, B.4
Zethelius, B.5
Lind, L.6
-
76
-
-
0037035446
-
Proinsulin is an independent predictor of coronary heart disease: Report from a 27-year follow-up study
-
DOI 10.1161/01.CIR.0000015855.04844.E7
-
Zethelius B, Byberg L, Hales CN, et al. Proinsulin is an independent predictor of coronary heart disease: report from a 27-year follow-up study. Circulation 2002;105:2153-8 (Pubitemid 34517158)
-
(2002)
Circulation
, vol.105
, Issue.18
, pp. 2153-2158
-
-
Zethelius, B.1
Byberg, L.2
Hales, C.N.3
Lithell, H.4
Berne, C.5
-
77
-
-
33947304608
-
Effect of simvastatin and/or pioglitazone on insulin resistance, insulin secretion, adiponectin, and proinsulin levels in nondiabetic patients at cardiovascular risk-the PIOSTAT Study
-
DOI 10.1016/j.metabol.2006.11.007, PII S002604950600432X
-
Forst T, Pfutzner A, Lubben G, et al. Effect of simvastatin and/or pioglitazone on insulin resistance, insulin secretion, adiponectin, and proinsulin levels in nondiabetic patients at cardiovascular risk-the PIOSTAT Study. Metabolism 2007;56:491-6 (Pubitemid 46437254)
-
(2007)
Metabolism: Clinical and Experimental
, vol.56
, Issue.4
, pp. 491-496
-
-
Forst, T.1
Pfutzner, A.2
Lubben, G.3
Weber, M.4
Marx, N.5
Karagiannis, E.6
Koehler, C.7
Baurecht, W.8
Hohberg, C.9
Hanefeld, M.10
-
78
-
-
0036315001
-
Relationships among age, proinsulin conversion, and β-cell function in nondiabetic humans
-
Fritsche A, Madaus A, Stefan N, et al. Relationships among age, proinsulin conversion, and beta-cell function in nondiabetic humans. Diabetes 2002;51(Suppl 1):S234-9 (Pubitemid 34761521)
-
(2002)
Diabetes
, vol.51
, Issue.SUPPL.
-
-
Fritsche, A.1
Madaus, A.2
Stefan, N.3
Tschritter, O.4
Maerker, E.5
Teigeler, A.6
Haring, H.7
Stumvoll, M.8
-
79
-
-
18144401971
-
Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2
-
DOI 10.2337/diacare.28.5.1092
-
DeFronzo RA, Ratner RE, Han J, et al. Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes. Diabetes Care 2005;28:1092-100 (Pubitemid 40616618)
-
(2005)
Diabetes Care
, vol.28
, Issue.5
, pp. 1092-1100
-
-
DeFronzo, R.A.1
Ratner, R.E.2
Han, J.3
Kim, D.D.4
Fineman, M.S.5
Baron, A.D.6
-
80
-
-
39749143348
-
Liraglutide, a once-daily human GLP-1 analogue, improves pancreatic B-cell function and arginine-stimulated insulin secretion during hyperglycaemia in patients with Type 2 diabetes mellitus
-
DOI 10.1111/j.1464-5491.2007.02333.x
-
Vilsboll T, Brock B, Perrild H, et al. Liraglutide, a once-daily human GLP-1 analogue, improves pancreatic B-cell function and arginine-stimulated insulin secretion during hyperglycaemia in patients with type 2 diabetes mellitus. Diabet Med 2008;25:152-6 (Pubitemid 351293400)
-
(2008)
Diabetic Medicine
, vol.25
, Issue.2
, pp. 152-156
-
-
Vilsboll, T.1
Brock, B.2
Perrild, H.3
Levin, K.4
Lervang, H.-H.5
Kolendorf, K.6
Krarup, T.7
Schmitz, O.8
Zdravkovic, M.9
Le-Thi, T.10
Madsbad, S.11
-
81
-
-
78851472527
-
Effect of linagliptin monotherapy on glycaemic control and markers of beta-cell function in patients with inadequately controlled type 2 diabetes: A randomized controlled trial
-
Del Prato S, Barnett AH, Huisman H, et al. Effect of linagliptin monotherapy on glycaemic control and markers of beta-cell function in patients with inadequately controlled type 2 diabetes: a randomized controlled trial. Diabetes Obes Metab 2011;13:258-67
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 258-267
-
-
Del Prato, S.1
Barnett, A.H.2
Huisman, H.3
-
82
-
-
52249090472
-
Robust improvements in fasting and prandial measures of beta-cell function with vildagliptin in drug-naive patients: Analysis of pooled vildagliptin monotherapy database
-
Pratley RE, Schweizer A, Rosenstock J, et al. Robust improvements in fasting and prandial measures of beta-cell function with vildagliptin in drug-naive patients: analysis of pooled vildagliptin monotherapy database. Diabetes Obes Metab 2008;10:931-8
-
(2008)
Diabetes Obes Metab
, vol.10
, pp. 931-938
-
-
Pratley, R.E.1
Schweizer, A.2
Rosenstock, J.3
-
83
-
-
33845489598
-
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy in patients with type 2 diabetes mellitus
-
Raz I, Hanefeld M, Xu L, et al. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy in patients with type 2 diabetes mellitus. Diabetologia 2006;49:2564-71
-
(2006)
Diabetologia
, vol.49
, pp. 2564-2571
-
-
Raz, I.1
Hanefeld, M.2
Xu, L.3
-
84
-
-
84877618486
-
Effect of vildagliptin compared to glimepiride on postprandial proinsulin processing in the b cell of patients with type 2 diabetes mellitus
-
Forst T, Dworak M, Berndt-Zipfel C, et al. Effect of vildagliptin compared to glimepiride on postprandial proinsulin processing in the b cell of patients with type 2 diabetes mellitus. Diabetes Obes Metab 2013;15:576-9
-
(2013)
Diabetes Obes Metab
, vol.15
, pp. 576-579
-
-
Forst, T.1
Dworak, M.2
Berndt-Zipfel, C.3
-
85
-
-
43249085016
-
Enhanced protection against cytokine- and fatty acid-induced apoptosis in pancreatic beta cells by combined treatment with glucagon-like peptide-1 receptor agonists and insulin analogues
-
DOI 10.1055/s-2008-1042426
-
Tews D, Werner U, Eckel J. Enhanced protection against cytokine- and fatty acid-induced apoptosis in pancreatic beta cells by combined treatment with glucagon-like peptide-1 receptor agonists and insulin analogues. Horm Metab Res 2008;40:172-80 (Pubitemid 351690520)
-
(2008)
Hormone and Metabolic Research
, vol.40
, Issue.3
, pp. 172-180
-
-
Tews, D.1
Werner, U.2
Eckel, J.3
-
86
-
-
43049116613
-
The GLP-1 receptor agonist AVE0010 preserves beta cell function and insulin secretion after a 6 week treatment in make obese Zucker diabetic fatty rats - an isolated perfusion pancreas study [abstract]
-
Haschke G, Haag-Diergarten S, Werner U, et al. The GLP-1 receptor agonist AVE0010 preserves beta cell function and insulin secretion after a 6 week treatment in make obese Zucker diabetic fatty rats - an isolated perfusion pancreas study [abstract]. Diabetologia 2006;49:400-1
-
(2006)
Diabetologia
, vol.49
, pp. 400-401
-
-
Haschke, G.1
Haag-Diergarten, S.2
Werner, U.3
-
87
-
-
84885584650
-
Restitution of glucose disposition with lixisenatide in healthy subjects and patients with type 2 diabetes [abstract 813]
-
Becker RH, Kapitza C, Stechl J, et al. Restitution of glucose disposition with lixisenatide in healthy subjects and patients with type 2 diabetes [abstract 813]. Diabetologia 2012;55:S1-S538
-
(2012)
Diabetologia
, vol.55
-
-
Becker, R.H.1
Kapitza, C.2
Stechl, J.3
-
88
-
-
84885644827
-
Post-meal pharmacodynamic profile of lixisenatide once daily vs placebo in T2DM insufficiently controlled on sulfonylureametformin (GetGoal-S) [abstract D-0743]
-
5 - 8 December Dubai, United Arab Emirates; 2011
-
Ratner RE, Hanefeld M, Shamanna P, et al. Post-meal pharmacodynamic profile of lixisenatide once daily vs placebo in T2DM insufficiently controlled on sulfonylureametformin (GetGoal-S) [abstract D-0743]. Poster presented at the International Diabetes Federation's 21st World Diabetes Congress; 5 - 8 December 2011; Dubai, United Arab Emirates; 2011
-
(2011)
Poster Presented at the International Diabetes Federation's 21st World Diabetes Congress
-
-
Ratner, R.E.1
Hanefeld, M.2
Shamanna, P.3
-
89
-
-
0026596851
-
Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus
-
Gutniak M, Orskov C, Holst JJ, et al. Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus. N Engl J Med 1992;326:1316-22
-
(1992)
N Engl J Med
, vol.326
, pp. 1316-1322
-
-
Gutniak, M.1
Orskov, C.2
Holst, J.J.3
-
90
-
-
0027248866
-
Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in Type 2 (non-insulin-dependent) diabetic patients
-
Nauck MA, Kleine N, Orskov C, et al. Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7- 36 amide) in type 2 (non-insulindependent) diabetic patients. Diabetologia 1993;36:741-4 (Pubitemid 23218642)
-
(1993)
Diabetologia
, vol.36
, Issue.8
, pp. 741-744
-
-
Nauck, M.A.1
Kleine, N.2
Orskov, C.3
Holst, J.J.4
Willms, B.5
Creutzfeldt, W.6
-
91
-
-
0037045845
-
Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and β-cell function in type 2 diabetes: A parallel-group study
-
DOI 10.1016/S0140-6736(02)07952-7
-
Zander M, Madsbad S, Madsen JL, Holst JJ. Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study. Lancet 2002;359:824-30 (Pubitemid 34233752)
-
(2002)
Lancet
, vol.359
, Issue.9309
, pp. 824-830
-
-
Zander, M.1
Madsbad, S.2
Madsen, J.L.3
Holst, J.J.4
-
92
-
-
0037386156
-
Glucagon-like peptide-1 inhibits apoptosis of insulin-secreting cells via a cyclic 5′-adenosine monophosphate-dependent protein kinase A- and a phosphatidylinositol 3-kinase-dependent pathway
-
DOI 10.1210/en.2002-220897
-
Hui H, Nourparvar A, Zhao X, Perfetti R. Glucagon-like peptide-1 inhibits apoptosis of insulin-secreting cells via a cyclic5'-adenosine monophosphate-dependent protein kinase A- and a phosphatidylinositol 3-kinase-dependent pathway. Endocrinology 2003;144:1444-55 (Pubitemid 36432086)
-
(2003)
Endocrinology
, vol.144
, Issue.4
, pp. 1444-1455
-
-
Hui, H.1
Nourparvar, A.2
Zhao, X.3
Perfetti, R.4
-
93
-
-
0030913210
-
Glucagon-like peptide-1 can reverse the age-related decline in glucose tolerance in rats
-
Wang Y, Perfetti R, Greig NH, et al. Glucagon-like peptide-1 can reverse the age-related decline in glucose tolerance in rats. J Clin Invest 1997;99:2883-9 (Pubitemid 27278664)
-
(1997)
Journal of Clinical Investigation
, vol.99
, Issue.12
, pp. 2883-2889
-
-
Wang, Y.1
Perfetti, R.2
Greig, N.H.3
Holloway, H.W.4
DeOre, K.A.5
Montrose-Rafizadeh, C.6
Elahi, D.7
Egan, J.M.8
-
94
-
-
0027391607
-
Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type- 2 diabetes mellitus
-
Nauck MA, Heimesaat MM, Orskov C, et al. Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus. J Clin Invest 1993;91:301-7 (Pubitemid 23037285)
-
(1993)
Journal of Clinical Investigation
, vol.91
, Issue.1
, pp. 301-307
-
-
Nauck, M.A.1
Heimesaat, M.M.2
Orskov, C.3
Holst, J.J.4
Ebert, R.5
Creutzfeldt, W.6
-
95
-
-
0043169338
-
Differential effects of acute and extended infusions of glucagon-like peptide-1 on first- and second-phase insulin secretion in diabetic and nondiabetic humans
-
DOI 10.2337/diacare.26.3.791
-
Quddusi S, Vahl TP, Hanson K, et al. Differential effects of acute and extended infusions of glucagon-like peptide-1 on first- and second-phase insulin secretion in diabetic and nondiabetic humans. Diabetes Care 2003;26:791-8 (Pubitemid 36929345)
-
(2003)
Diabetes Care
, vol.26
, Issue.3
, pp. 791-798
-
-
Quddusi, S.1
Vahl, T.P.2
Hanson, K.3
Prigeon, R.L.4
D'Alessio, D.A.5
-
96
-
-
84860204551
-
Cardiovascular biology of the incretin system
-
Ussher JR, Drucker DJ. Cardiovascular biology of the incretin system. Endocr Rev 2012;33:187-215
-
(2012)
Endocr Rev
, vol.33
, pp. 187-215
-
-
Ussher, J.R.1
Drucker, D.J.2
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