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Volumn 185, Issue , 2013, Pages 1-8

Effects of lixisenatide once daily on gastric emptying in type 2 diabetes - Relationship to postprandial glycemia

Author keywords

Gastric emptying; Glucagon like peptide 1 receptor agonist; Lixisenatide; Postprandial blood glucose; Type 2 diabetes

Indexed keywords

C PEPTIDE; GLUCAGON; HEMOGLOBIN A1C; INSULIN; LIXISENATIDE; METFORMIN; OCTANOIC ACID C 13; PLACEBO; SULFONYLUREA DERIVATIVE;

EID: 84878549237     PISSN: 01670115     EISSN: 18731686     Source Type: Journal    
DOI: 10.1016/j.regpep.2013.04.001     Document Type: Article
Times cited : (126)

References (38)
  • 1
    • 84866268783 scopus 로고    scopus 로고
    • Management of hyperglycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
    • Inzucchi S.E., Bergenstal R.M., Buse J.B., Diamant M., Ferrannini E., Nauck M., Peters A.L., Tsapas A., Wender R., Matthews D.R. Management of hyperglycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care 2012, 35:1364-1379.
    • (2012) Diabetes Care , vol.35 , pp. 1364-1379
    • Inzucchi, S.E.1    Bergenstal, R.M.2    Buse, J.B.3    Diamant, M.4    Ferrannini, E.5    Nauck, M.6    Peters, A.L.7    Tsapas, A.8    Wender, R.9    Matthews, D.R.10
  • 2
    • 33846006173 scopus 로고    scopus 로고
    • The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
    • Drucker D.J., Nauck M.A. The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. Lancet 2006, 368:1696-1705.
    • (2006) Lancet , vol.368 , pp. 1696-1705
    • Drucker, D.J.1    Nauck, M.A.2
  • 3
    • 78650753885 scopus 로고    scopus 로고
    • Incretin-based therapies for type 2 diabetes mellitus: properties, functions, and clinical implications
    • Nauck M.A. Incretin-based therapies for type 2 diabetes mellitus: properties, functions, and clinical implications. Am J Med 2011, 124:S3-S18.
    • (2011) Am J Med , vol.124
    • Nauck, M.A.1
  • 4
    • 84870054636 scopus 로고    scopus 로고
    • GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus
    • Meier J.J. GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus. Nat Rev Endocrinol 2012, 8:728-742.
    • (2012) Nat Rev Endocrinol , vol.8 , pp. 728-742
    • Meier, J.J.1
  • 6
    • 0027281591 scopus 로고
    • Relationship between oral glucose tolerance and gastric emptying in normal healthy subjects
    • Horowitz M., Edelbroek M.A., Wishart J.M., Straathof J.W. Relationship between oral glucose tolerance and gastric emptying in normal healthy subjects. Diabetologia 1993, 36:857-862.
    • (1993) Diabetologia , vol.36 , pp. 857-862
    • Horowitz, M.1    Edelbroek, M.A.2    Wishart, J.M.3    Straathof, J.W.4
  • 8
    • 0037339148 scopus 로고    scopus 로고
    • Effect of altering gastric emptying on postprandial plasma glucose concentrations following a physiologic meal in type-II diabetic patients
    • Gonlachanvit S., Hsu C.W., Boden G.H., Knight L.C., Maurer A.H., Fisher R.S., Parkman H.P. Effect of altering gastric emptying on postprandial plasma glucose concentrations following a physiologic meal in type-II diabetic patients. Dig Dis Sci 2003, 48:488-497.
    • (2003) Dig Dis Sci , vol.48 , pp. 488-497
    • Gonlachanvit, S.1    Hsu, C.W.2    Boden, G.H.3    Knight, L.C.4    Maurer, A.H.5    Fisher, R.S.6    Parkman, H.P.7
  • 9
    • 80052812653 scopus 로고    scopus 로고
    • Effects of GLP-1 and incretin-based therapies on gastrointestinal motor function
    • Marathe C.S., Rayner C.K., Jones K.L., Horowitz M. Effects of GLP-1 and incretin-based therapies on gastrointestinal motor function. Exp Diabetes Res 2011, 2011:279530.
    • (2011) Exp Diabetes Res , vol.2011 , pp. 279530
    • Marathe, C.S.1    Rayner, C.K.2    Jones, K.L.3    Horowitz, M.4
  • 10
    • 0025822723 scopus 로고
    • Disordered gastric emptying: mechanical basis, assessment and treatment
    • Horowitz M., Dent J. Disordered gastric emptying: mechanical basis, assessment and treatment. Baillieres Clin Gastroenterol 1991, 5:371-407.
    • (1991) Baillieres Clin Gastroenterol , vol.5 , pp. 371-407
    • Horowitz, M.1    Dent, J.2
  • 11
    • 0035141010 scopus 로고    scopus 로고
    • Relationships of upper gastrointestinal motor and sensory function with glycemic control
    • Rayner C.K., Samsom M., Jones K.L., Horowitz M. Relationships of upper gastrointestinal motor and sensory function with glycemic control. Diabetes Care 2001, 24:371-381.
    • (2001) Diabetes Care , vol.24 , pp. 371-381
    • Rayner, C.K.1    Samsom, M.2    Jones, K.L.3    Horowitz, M.4
  • 13
    • 33646394592 scopus 로고    scopus 로고
    • Effects of intravenous glucagon-like peptide-1 on gastric emptying and intragastric distribution in healthy subjects: relationships with postprandial glycemic and insulinemic responses
    • Little T.J., Pilichiewicz A.N., Russo A., Phillips L., Jones K.L., Nauck M.A., Wishart J., Horowitz M., Feinle-Bisset C. Effects of intravenous glucagon-like peptide-1 on gastric emptying and intragastric distribution in healthy subjects: relationships with postprandial glycemic and insulinemic responses. J Clin Endocrinol Metab 2006, 91:1916-1923.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1916-1923
    • Little, T.J.1    Pilichiewicz, A.N.2    Russo, A.3    Phillips, L.4    Jones, K.L.5    Nauck, M.A.6    Wishart, J.7    Horowitz, M.8    Feinle-Bisset, C.9
  • 14
    • 79959404178 scopus 로고    scopus 로고
    • Rapid tachyphylaxis of the glucagon-like peptide 1-induced deceleration of gastric emptying in humans
    • Nauck M.A., Kemmeries G., Holst J.J., Meier J.J. Rapid tachyphylaxis of the glucagon-like peptide 1-induced deceleration of gastric emptying in humans. Diabetes 2011, 60:1561-1565.
    • (2011) Diabetes , vol.60 , pp. 1561-1565
    • Nauck, M.A.1    Kemmeries, G.2    Holst, J.J.3    Meier, J.J.4
  • 15
    • 79958094404 scopus 로고    scopus 로고
    • The once-daily human glucagon-like peptide-1 (GLP-1) analog liraglutide improves postprandial glucose levels in type 2 diabetes patients
    • Flint A., Kapitza C., Hindsberger C., Zdravkovic M. The once-daily human glucagon-like peptide-1 (GLP-1) analog liraglutide improves postprandial glucose levels in type 2 diabetes patients. Adv Ther 2011, 28:213-226.
    • (2011) Adv Ther , vol.28 , pp. 213-226
    • Flint, A.1    Kapitza, C.2    Hindsberger, C.3    Zdravkovic, M.4
  • 16
    • 53249142132 scopus 로고    scopus 로고
    • Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study
    • Drucker D.J., Buse J.B., Taylor K., Kendall D.M., Trautmann M., Zhuang D., Porter L. Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study. Lancet 2008, 372:1240-1250.
    • (2008) Lancet , vol.372 , pp. 1240-1250
    • Drucker, D.J.1    Buse, J.B.2    Taylor, K.3    Kendall, D.M.4    Trautmann, M.5    Zhuang, D.6    Porter, L.7
  • 17
    • 77955887980 scopus 로고    scopus 로고
    • Dose-dependent effects of the once-daily GLP-1 receptor agonist lixisenatide in patients with Type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled trial
    • Ratner R.E., Rosenstock J., Boka G. Dose-dependent effects of the once-daily GLP-1 receptor agonist lixisenatide in patients with Type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled trial. Diabet Med 2010, 27:1024-1032.
    • (2010) Diabet Med , vol.27 , pp. 1024-1032
    • Ratner, R.E.1    Rosenstock, J.2    Boka, G.3
  • 18
    • 84878863716 scopus 로고    scopus 로고
    • Pharmacodynamic characteristics of lixisenatide once daily vs liraglutide once daily in patients with T2DM inadequately controlled with metformin
    • (in press)
    • Kapitza C., Forst T., Coester H.C., Poitiers F., Ruus P., Hincelin-Méry A. Pharmacodynamic characteristics of lixisenatide once daily vs liraglutide once daily in patients with T2DM inadequately controlled with metformin. Diabetes Obes Metab 2013, (in press). 10.1111/dom. 12076.
    • (2013) Diabetes Obes Metab
    • Kapitza, C.1    Forst, T.2    Coester, H.C.3    Poitiers, F.4    Ruus, P.5    Hincelin-Méry, A.6
  • 19
    • 84861765116 scopus 로고    scopus 로고
    • Efficacy and safety of the once-daily GLP-1 receptor agonist lixisenatide in monotherapy: a randomized, double-blind, placebo-controlled trial in patients with type 2 diabetes (GetGoal-Mono)
    • Fonseca V.A., Alvarado-Ruiz R., Raccah D., Boka G., Miossec P., Gerich J.E. Efficacy and safety of the once-daily GLP-1 receptor agonist lixisenatide in monotherapy: a randomized, double-blind, placebo-controlled trial in patients with type 2 diabetes (GetGoal-Mono). Diabetes Care 2012, 35:1225-1231.
    • (2012) Diabetes Care , vol.35 , pp. 1225-1231
    • Fonseca, V.A.1    Alvarado-Ruiz, R.2    Raccah, D.3    Boka, G.4    Miossec, P.5    Gerich, J.E.6
  • 20
    • 84885331631 scopus 로고    scopus 로고
    • Efficacy and safety of lixisenatide once daily versus placebo in patients with type 2 diabetes insufficiently controlled on pioglitazone (GetGoal-P)
    • [in press]
    • Pinget M., Goldenberg R., Niemoeller E., Muehlen-Bartmer I., Guo H., Aronson R. Efficacy and safety of lixisenatide once daily versus placebo in patients with type 2 diabetes insufficiently controlled on pioglitazone (GetGoal-P). Diabetes Obes Metab 2013, [in press]. 10.1111/dom.12121.
    • (2013) Diabetes Obes Metab
    • Pinget, M.1    Goldenberg, R.2    Niemoeller, E.3    Muehlen-Bartmer, I.4    Guo, H.5    Aronson, R.6
  • 21
    • 84878622377 scopus 로고    scopus 로고
    • Efficacy and safety of lixisenatide once-daily versus placebo in patients with T2DM insufficiently controlled on metformin (GetGoal-F1)
    • Diabetologia, Lisbon Portugal, [Suppl 1, (Abstract 784)], Poster presented at 47th Annual Meeting of the European Association for the Study of Diabetes 2013;16 S 2011 12
    • Bolli G., Munteanu M., Dotsenko S., Niemoeller E., Boka G., Hanefield M. Efficacy and safety of lixisenatide once-daily versus placebo in patients with T2DM insufficiently controlled on metformin (GetGoal-F1). Diabetologia 2011 12-16 September 2011, 54:1-542. Diabetologia, Lisbon Portugal, [Suppl 1, (Abstract 784)].
    • Diabetologia 2011 , vol.54 , pp. 1-542
    • Bolli, G.1    Munteanu, M.2    Dotsenko, S.3    Niemoeller, E.4    Boka, G.5    Hanefield, M.6
  • 22
    • 84878358313 scopus 로고    scopus 로고
    • Efficacy and Safety of Lixisenatide Once-Daily Morning or Evening Injections in Type 2 Diabetes Inadequately Controlled on Metformin (GetGoal-M)
    • [in press]
    • Ahrén B., Leguizamo Dimas A., Miossec P., Saubado S., Aronson R. Efficacy and Safety of Lixisenatide Once-Daily Morning or Evening Injections in Type 2 Diabetes Inadequately Controlled on Metformin (GetGoal-M). Diabetes Care 2013, [in press]. 10.2337/dc12-2006.
    • (2013) Diabetes Care
    • Ahrén, B.1    Leguizamo Dimas, A.2    Miossec, P.3    Saubado, S.4    Aronson, R.5
  • 23
    • 84878622377 scopus 로고    scopus 로고
    • Efficacy and safety of lixisenatide once daily versus placebo in patients with T2DM insufficiently controlled on sulfonylurea±metformin (GetGoal-S)
    • [(Suppl 1): 1-542 (Abstract 785)], Poster presented at 47th Annual Meeting of the European Association for the Study of Diabetes, 12-16 September 2011, Lisbon, Portugal
    • Ratner R., Hanefield M., Shamanna P., Min K., Boka G., Miossec P., Muehlen-Bartmer I., Rosenstock J. Efficacy and safety of lixisenatide once daily versus placebo in patients with T2DM insufficiently controlled on sulfonylurea±metformin (GetGoal-S). Diabetologia 2011, 54. [(Suppl 1): 1-542 (Abstract 785)].
    • (2011) Diabetologia , vol.54
    • Ratner, R.1    Hanefield, M.2    Shamanna, P.3    Min, K.4    Boka, G.5    Miossec, P.6    Muehlen-Bartmer, I.7    Rosenstock, J.8
  • 24
    • 84878592117 scopus 로고    scopus 로고
    • Adding Once-Daily Lixisenatide for Type 2 Diabetes Inadequately Controlled With Newly Initiated and Continuously Titrated Basal Insulin Glargine: A 24-Week, Randomized, Placebo-Controlled Study (GetGoal-Duo 1)
    • [in press]
    • Riddle M.C., Forst T., Aronson R., Sauque-Reyna L., Souhami E., Silvestre L., Ping L., Rosenstock J. Adding Once-Daily Lixisenatide for Type 2 Diabetes Inadequately Controlled With Newly Initiated and Continuously Titrated Basal Insulin Glargine: A 24-Week, Randomized, Placebo-Controlled Study (GetGoal-Duo 1). Diabetes Care 2013, [in press]. 10.2337/dc12-246.
    • (2013) Diabetes Care
    • Riddle, M.C.1    Forst, T.2    Aronson, R.3    Sauque-Reyna, L.4    Souhami, E.5    Silvestre, L.6    Ping, L.7    Rosenstock, J.8
  • 25
    • 84878592117 scopus 로고    scopus 로고
    • Adding Once-Daily Lixisenatide for Type 2 Diabetes Inadequately Controlled by Established Basal Insulin: A 24-week, randomized, placebo-controlled comparison (GetGoal-L)
    • [in press]
    • Riddle M.C., Aronson R., Home P., Marre M., Niemoeller E., Miossec P., Ping L., Ye J., Rosenstock J. Adding Once-Daily Lixisenatide for Type 2 Diabetes Inadequately Controlled by Established Basal Insulin: A 24-week, randomized, placebo-controlled comparison (GetGoal-L). Diabetes Care 2013, [in press]. 10.2337/dc12-2454.
    • (2013) Diabetes Care
    • Riddle, M.C.1    Aronson, R.2    Home, P.3    Marre, M.4    Niemoeller, E.5    Miossec, P.6    Ping, L.7    Ye, J.8    Rosenstock, J.9
  • 26
    • 84865979163 scopus 로고    scopus 로고
    • Randomized, double-blind, placebo-controlled trial of the once-daily GLP-1 receptor agonist lixisenatide in Asian patients with type 2 diabetes insufficiently controlled on basal insulin with or without a sulfonylurea (GetGoal-L-Asia)
    • Seino Y., Min K.W., Niemoeller E., Takami A. Randomized, double-blind, placebo-controlled trial of the once-daily GLP-1 receptor agonist lixisenatide in Asian patients with type 2 diabetes insufficiently controlled on basal insulin with or without a sulfonylurea (GetGoal-L-Asia). Diabetes Obes Metab 2012 Oct, 14(10):910-917.
    • (2012) Diabetes Obes Metab , vol.14 , Issue.10 , pp. 910-917
    • Seino, Y.1    Min, K.W.2    Niemoeller, E.3    Takami, A.4
  • 27
    • 85172038734 scopus 로고    scopus 로고
    • [Accessed 12 March 2013]
    • [Accessed 12 March 2013]. http://ec.europa.eu/health/documents/community-register/html/h811.htm.
  • 29
    • 0042166232 scopus 로고    scopus 로고
    • Contributions of fasting and postprandial plasma glucose increments to the overall diurnal hyperglycemia of type 2 diabetic patients: variations with increasing levels of HbA(1c)
    • Monnier L., Lapinski H., Colette C. Contributions of fasting and postprandial plasma glucose increments to the overall diurnal hyperglycemia of type 2 diabetic patients: variations with increasing levels of HbA(1c). Diabetes Care 2003, 26:881-885.
    • (2003) Diabetes Care , vol.26 , pp. 881-885
    • Monnier, L.1    Lapinski, H.2    Colette, C.3
  • 30
    • 34247636085 scopus 로고    scopus 로고
    • Impact of fasting and postprandial glycemia on overall glycemic control in type 2 diabetes Importance of postprandial glycemia to achieve target HbA1c levels
    • Woerle H.J., Neumann C., Zschau S., Tenner S., Irsigler A., Schirra J., Gerich J.E., Goke B. Impact of fasting and postprandial glycemia on overall glycemic control in type 2 diabetes Importance of postprandial glycemia to achieve target HbA1c levels. Diabetes Res Clin Pract 2007, 77:280-285.
    • (2007) Diabetes Res Clin Pract , vol.77 , pp. 280-285
    • Woerle, H.J.1    Neumann, C.2    Zschau, S.3    Tenner, S.4    Irsigler, A.5    Schirra, J.6    Gerich, J.E.7    Goke, B.8
  • 31
    • 85172040444 scopus 로고    scopus 로고
    • 2011 Guideline for Management of PostMeal Glucose in Diabetes
    • 2011 Guideline for Management of PostMeal Glucose in Diabetes International Diabetes Federation 2011, http://www.idf.org/sites/default/files/postmeal%20glucose%20guidelines.pdf.
    • (2011) International Diabetes Federation
  • 32
    • 66749181130 scopus 로고    scopus 로고
    • Postprandial hyperglycemia as an etiological factor in vascular failure
    • Node K., Inoue T. Postprandial hyperglycemia as an etiological factor in vascular failure. Cardiovasc Diabetol 2009, 8:23.
    • (2009) Cardiovasc Diabetol , vol.8 , pp. 23
    • Node, K.1    Inoue, T.2
  • 35
    • 2342599057 scopus 로고    scopus 로고
    • One week's treatment with the long-acting glucagon-like peptide 1 derivative liraglutide (NN2211) markedly improves 24-h glycemia and alpha- and beta-cell function and reduces endogenous glucose release in patients with type 2 diabetes
    • Degn K.B., Juhl C.B., Sturis J., Jakobsen G., Brock B., Chandramouli V., Rungby J., Landau B.R., Schmitz O. One week's treatment with the long-acting glucagon-like peptide 1 derivative liraglutide (NN2211) markedly improves 24-h glycemia and alpha- and beta-cell function and reduces endogenous glucose release in patients with type 2 diabetes. Diabetes 2004, 53:1187-1194.
    • (2004) Diabetes , vol.53 , pp. 1187-1194
    • Degn, K.B.1    Juhl, C.B.2    Sturis, J.3    Jakobsen, G.4    Brock, B.5    Chandramouli, V.6    Rungby, J.7    Landau, B.R.8    Schmitz, O.9
  • 36
    • 77952118055 scopus 로고    scopus 로고
    • Available at, [Accessed 12 March 2013]
    • Bydureon Summary of Product Characteristics Available at, [Accessed 12 March 2013]. http://ec.europa.eu/health/documents/community-register/2011/20110617103730/anx_103730_en.pdf.
    • Bydureon Summary of Product Characteristics
  • 37
    • 67649666737 scopus 로고    scopus 로고
    • Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6)
    • Buse J.B., Rosenstock J., Sesti G., Schmidt W.E., Montanya E., Brett J.H., Zychma M., Blonde L. Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6). Lancet 2009, 374:39-47.
    • (2009) Lancet , vol.374 , pp. 39-47
    • Buse, J.B.1    Rosenstock, J.2    Sesti, G.3    Schmidt, W.E.4    Montanya, E.5    Brett, J.H.6    Zychma, M.7    Blonde, L.8
  • 38
    • 0142179159 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 receptor agonist ZP10A increases insulin mRNA expression and prevents diabetic progression in db/db mice
    • Thorkildsen C., Neve S., Larsen B.D., Meier E., Petersen J.S. Glucagon-like peptide 1 receptor agonist ZP10A increases insulin mRNA expression and prevents diabetic progression in db/db mice. J Pharmacol Exp Ther 2003, 307:490-496.
    • (2003) J Pharmacol Exp Ther , vol.307 , pp. 490-496
    • Thorkildsen, C.1    Neve, S.2    Larsen, B.D.3    Meier, E.4    Petersen, J.S.5


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