Epimorphin deletion inhibits polyposis in the Apcmin/+ mouse model of colon carcinogenesis via decreased myofibroblast HGF secretion

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 305, Issue 8, 2013, Pages

  Swietlicki, Elzbieta A ^a   Bala, Shashi ^a   Lu, Jianyun ^a   Shaker, Anisa ^a   Kularatna, Gowri ^a   Levin, Marc S ^a,b   Rubin, Deborah C ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b St Louis Veterans Administration   (United States)

Author keywords

Colon cancer; Hepatocyte growth factor; Myofibroblasts; Stem cell niche; Tumor microenvironment

Indexed keywords

APC PROTEIN; SCATTER FACTOR; SMAD2 PROTEIN; SMAD3 PROTEIN; SYNTAXIN 2; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLON; COLON CARCINOGENESIS; COLON POLYPOSIS; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION; INTESTINE MUCOSA; MALE; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SMALL INTESTINE;

COLON CANCER; HEPATOCYTE GROWTH FACTOR; MYOFIBROBLASTS; STEM CELL NICHE; TUMOR MICROENVIRONMENT;

ADENOMATOUS POLYPOSIS COLI; ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; COLONIC NEOPLASMS; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; HEPATOCYTE GROWTH FACTOR; INTESTINAL MUCOSA; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOFIBROBLASTS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 84885631689     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00486.2012     Document Type: Article

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