Deficiency of Kruppel-like factor KLF4 in mammary tumor cells inhibits tumor growth and pulmonary metastasis and is accompanied by compromised recruitment of myeloid-derived suppressor cells

International Journal of Cancer

Volumn 133, Issue 12, 2013, Pages 2872-2883

  Yu, Fang ^a,b   Shi, Ying ^a,c   Wang, Junfeng ^a,c   Li, Juan ^a,c   Fan, Daping ^a   Ai, Walden ^a  

^a UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

CXCL5; GM CSF; KLF4; myeloid derived suppressor cells; tumor development

Indexed keywords

EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; GRANULOCYTE COLONY STIMULATING FACTOR; KRUPPEL LIKE FACTOR 4;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BONE MARROW CELL; BREAST CARCINOGENESIS; BREAST METASTASIS; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL MIGRATION; CONTROLLED STUDY; FEMALE; GENE FUNCTION; GENE SILENCING; IMMUNOMODULATION; KLF4 GENE; LUNG METASTASIS; METASTASIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; SUPPRESSOR CELL; TUMOR MICROENVIRONMENT;

CXCL5; GM-CSF; KLF4; MYELOID-DERIVED SUPPRESSOR CELLS; TUMOR DEVELOPMENT;

BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CHEMOKINE CXCL5; FEMALE; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; IMMUNE TOLERANCE; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LUNG NEOPLASMS; MYELOID CELLS; TUMOR BURDEN;

EID: 84885624626     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28302     Document Type: Article

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