Staurosporine induces dopaminergic neurite outgrowth through AMP-activated protein kinase/mammalian target of rapamycin signaling pathway

Neuropharmacology

Volumn 77, Issue , 2014, Pages 39-48

  Wakita, Seiko ^a   Izumi, Yasuhiko ^a   Nakai, Toshie ^a   Adachi, Kanami ^a   Takada Takatori, Yuki ^b   Kume, Toshiaki ^a   Akaike, Akinori ^a,c  

^a KYOTO UNIVERSITY   (Japan)

^b DOSHISHA WOMEN'S COLLEGE OF LIBERAL ARTS   (Japan)

^c NAGOYA UNIVERSITY   (Japan)

Author keywords

1 Methyl 4 phenylpyridinium ion; AMP activated protein kinase; Dopaminergic neuron; Mammalian target of rapamycin; Neurite outgrowth; Staurosporine

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; S6 KINASE; STAUROSPORINE;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOPAMINERGIC ACTIVITY; DOPAMINERGIC NERVE CELL; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MESENCEPHALON; MITOCHONDRIAL MEMBRANE POTENTIAL; NERVE FIBER DEGENERATION; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; 1-METHYL-4-PHENYLPYRIDINIUM ION; 70-KDA RIBOSOMAL PROTEIN S6 KINASE; AMP-ACTIVATED PROTEIN KINASE; AMPK; C-JUN NH2-TERMINAL KINASE; C.C; COLLAPSING RESPONSE MEDIATOR PROTEIN 2; COMPOUND C; CRMP2; DAB; DAYS IN VITRO; DIAMINOBENZIDINE; DIV; DMEM; DOPAMINERGIC NEURON; DULBECCO'S MODIFIED EAGLE MEDIUM; EAGLE'S MINIMUM ESSENTIAL MEDIUM; EMEM; FCS; FETAL CALF SERUM; HORSE SERUM; HS; JNK; MAMMALIAN TARGET OF RAPAMYCIN; MAP2; MICROTUBULE ASSOCIATED PROTEIN 2; MPP(+); MPTP; MTOR; NEURITE OUTGROWTH; P70S6K; PARKINSON DISEASE; PD; PHOSPHORYLATED NEUROFILAMENTS; PNF; STAUROSPORINE; STS; TETRAMETHYLRHODAMINE METHYL ESTER; TH; TMRM; TYROSINE HYDROXYLASE;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; DOPAMINERGIC NEURONS; ENZYME INHIBITORS; NEURITES; NEUROGENESIS; PC12 CELLS; PHOSPHORYLATION; RATS; SIGNAL TRANSDUCTION; STAUROSPORINE; TOR SERINE-THREONINE KINASES;

EID: 84885454592     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2013.09.012     Document Type: Article

References (35)

1. N. Abe, and V. Cavalli Nerve injury signaling Curr. Opin. Neurobiol. 18 2008 276 283
2. S. Amato, X. Liu, B. Zheng, L. Cantley, P. Rakic, and H.Y. Man AMP-activated protein kinase regulates neuronal polarization by interfering with PI 3-kinase localization Science 332 2011 247 251
3. H. Bernheimer, W. Birkmayer, O. Hornykiewicz, K. Jellinger, and F. Seitelberger Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations J. Neurol. Sci. 20 1973 415 455
4. + in vitro Cell. Biol. Int. 25 2001 981 984 (Pubitemid 32977046)
5. +-induced neurodegeneration J. Neurochem. 115 2010 247 258
6. H.C. Cheng, C.M. Ulane, and R.E. Burke Clinical progression in Parkinson disease and the neurobiology of axons Ann. Neurol. 67 2010 715 725
7. J.S. Choi, C. Park, and J.W. Jeong AMP-activated protein kinase is activated in Parkinson's disease models mediated by 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine Biochem. Biophys. Res. Commun. 391 2010 147 151
8. Y. Chu, G.A. Morfini, L.B. Langhamer, Y. He, S.T. Brady, and J.H. Kordower Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease Brain 135 2012 2058 2073
9. B. Dasgupta, and J. Milbrandt Resveratrol stimulates AMP kinase activity in neurons Proc. Natl. Acad. Sci. U. S. A 104 2007 7217 7222 (Pubitemid 47186035)
10. A. Domanskyi, C. Geissler, I.A. Vinnikov, H. Alter, A. Schober, M.A. Vogt, P. Gass, R. Parlato, and G. Schütz Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models FASEB. J. 25 2011 2898 2910
11. D.G. Hardie, I.P. Salt, S.A. Hawley, and S.P. Davies AMP-activated protein kinase: an ultrasensitive system for monitoring cellular energy charge Biochem. J. 338 1999 717 722 (Pubitemid 29140078)
12. N. Hay, and N. Sonenberg Upstream and downstream of mTOR Genes. Dev. 18 2004 1926 1945 (Pubitemid 39071573)
13. O. Hornykiewicz Biochemical aspects of Parkinson's disease Neurology 51 1998 S2 S9
14. A. Iizuka, K. Sengoku, M. Iketani, F. Nakamura, Y. Sato, M. Matsushita, A.C. Nairn, K. Takamatsu, Y. Goshima, and K. Takei Calcium-induced synergistic inhibition of a translational factor eEF2 in nerve growth cones Biochem. Biophys. Res. Commun. 353 2007 244 250 (Pubitemid 46014562)
15. Y. Izumi, N. Yamamoto, T. Matsuo, S. Wakita, H. Takeuchi, T. Kume, H. Katsuki, H. Sawada, and A. Akaike Vulnerability to glutamate toxicity of dopaminergic neurons is dependent on endogenous dopamine and MAPK activation J. Neurochem. 110 2009 745 755
16. A. Jalava, J. Heikkilä, M. Lintunen, K. Akerman, and S. Påhlman Staurosporine induces a neuronal phenotype in SH-SY5Y human neuroblastoma cells that resembles that induced by the phorbol ester 12-O-tetradecanoyl phorbol-13 acetate (TPA) FEBS. Lett. 300 1992 114 118
17. M.W. Karaman, S. Herrgard, D.K. Treiber, P. Gallant, C.E. Atteridge, B.T. Campbell, K.W. Chan, P. Ciceri, M.I. Davis, P.T. Edeen, R. Faraoni, M. Floyd, J.P. Hunt, D.J. Lockhart, Z.V. Milanov, M.J. Morrison, G. Pallares, H.K. Patel, S. Pritchard, L.M. Wodicka, and P.P. Zarrinkar A quantitative analysis of kinase inhibitor selectivity Nat. Biotechnol. 26 2008 127 132
18. S.K. Kim, and R.F. Novak The role of intracellular signaling in insulin-mediated regulation of drug metabolizing enzyme gene and protein expression Pharmacol. Ther. 113 2007 88 120 (Pubitemid 44969928)
19. Y.H. Kim, Y. Chang, and J.C. Jung Staurosporine induces ganglion cell differentiation in part by stimulating urokinase-type plasminogen activator expression and activation in the developing chick retina Biochem. Biophys. Res. Commun. 423 2012 67 72
20. +, specifically impairs mitochondrial transport in dopamine axons J. Neurosci. 31 2011 7212 7221
21. T. Kume, Y. Kawato, F. Osakada, Y. Izumi, H. Katsuki, T. Nakagawa, S. Kaneko, T. Niidome, Y. Takada-Takatori, and A. Akaike Dibutyryl cyclic AMP induces differentiation of human neuroblastoma SH-SY5Y cells into a noradrenergic phenotype Neurosci. Lett. 443 2008 199 203
22. H.G. Lee, S.Y. Kim, du S. Kim, S.R. Seo, S.I. Lee, D.M. Shin, P. De Smet, and J.T. Seo 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one inhibits neurite outgrowth and causes neurite retraction in PC12 cells independently of soluble guanylyl cyclase J. Neurosci. Res. 87 2009 269 277
23. C. Malagelada, E.J. Ryu, S.C. Biswas, V. Jackson-Lewis, and L.A. Greene RTP801 is elevated in Parkinson brain substantia nigral neurons and mediates death in cellular models of Parkinson's disease by a mechanism involving mammalian target of rapamycin inactivation J. Neurosci. 26 2006 9996 10005 (Pubitemid 44477161)
24. W. Meissner, C. Prunier, D. Guilloteau, S. Chalon, C.E. Gross, and E. Bezard Time-course of nigrostriatal degeneration in a progressive MPTP-lesioned macaque model of Parkinson's disease Mol. Neurobiol. 28 2003 209 218 (Pubitemid 38156419)
25. J.Y. Min, M.H. Park, M.K. Park, K.W. Park, N.W. Lee, T. Kim, H.J. Kim, and D.H. Lee Staurosporin induces neurite outgrowth through ROS generation in HN33 hippocampal cell lines J. Neural Transm. 113 2006 1821 1826 (Pubitemid 44657679)
26. T. Morita, and K. Sobue Specification of neuronal polarity regulated by local translation of CRMP2 and Tau via the mTOR-p70S6K pathway J. Biol. Chem. 284 2009 27734 27745
27. R.R. Ramsay, and T.P. Singer Energy-dependent uptake of N-methyl-4- phenylpyridinium, the neurotoxic metabolite of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine, by mitochondria J. Biol. Chem. 261 1986 7585 7587 (Pubitemid 17208669)
28. C. Rieker, D. Engblom, G. Kreiner, A. Domanskyi, A. Schober, S. Stotz, M. Neumann, X. Yuan, I. Grummt, G. Schütz, and R. Parlato Nucleolar disruption in dopaminergic neurons leads to oxidative damage and parkinsonism through repression of mammalian target of rapamycin signaling J. Neurosci. 31 2011 453 460
29. P.A. Serra, L. Sciola, M.R. Delogu, A. Spano, G. Monaco, E. Miele, G. Rocchitta, M. Miele, R. Migheli, and M.S. Desole The neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induces apoptosis in mouse nigrostriatal glia. Relevance to nigral neuronal death and striatal neurochemical changes J. Biol. Chem. 277 2002 34451 34461
30. R.J. Shaw LKB1 and AMP-activated protein kinase control of mTOR signalling and growth Acta Physiol. (Oxf) 196 2009 65 80
31. A.F. Thompson, and L.A. Levin Neuronal differentiation by analogs of staurosporine Neurochem. Int. 56 2010 554 560
32. L. Tönges, V. Planchamp, J.C. Koch, T. Herdegen, M. Bähr, and P. Lingor JNK isoforms differentially regulate neurite growth and regeneration in dopaminergic neurons in vitro J. Mol. Neurosci. 45 2011 284 293
33. V. Vingtdeux, P. Davies, D.W. Dickson, and P. Marambaud AMPK is abnormally activated in tangle- and pre-tangle-bearing neurons in Alzheimer's disease and other tauopathies Acta Neuropathol. 121 2011 337 349
34. S. Wakita, Y. Izumi, T. Matsuo, T. Kume, Y. Takada-Takatori, H. Sawada, and A. Akaike Reconstruction and quantitative evaluation of dopaminergic innervation of striatal neurons in dissociated primary cultures J. Neurosci. Methods 192 2010 83 89
35. R. Yao, M. Yoshihara, and H. Osada Specific activation of a c-Jun NH2-terminal kinase isoform and induction of neurite outgrowth in PC-12 cells by staurosporine J. Biol. Chem. 272 1997 18261 18266 (Pubitemid 27306415)