Microtubule assembly is directly affected by MPP+ in vitro

Cell Biology International

Volumn 25, Issue 10, 2001, Pages 981-984

  Cappelletti, Graziella ^a   Pedrotti, Barbara ^a   Maggioni, Maria Grazia ^a   Maci, Rosalba ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Microtubule assembly; MPP+; MPTP; Neurodegeneration

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; MICROTUBULE PROTEIN;

ANIMAL CELL; ARTICLE; CATTLE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; IN VITRO STUDY; MICROTUBULE ASSEMBLY; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PARKINSONISM; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION; TARGET CELL;

BOVINAE;

EID: 0034780223     PISSN: 10656995     EISSN: None     Source Type: Journal    
DOI: 10.1006/cbir.2001.0772     Document Type: Article

References (13)

1. + on the state of tubulin polymerisation in NGF-differentiated PC12 cells
2. Inhibition of dopamine uptake by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, a cause of parkinsonism
3. Microtubule polymerization dynamics
4. Filaments of Lewy bodies contain insoluble cytoskeletal elements
5. Filamentous nerve cell inclusions in neurodegenerative diseases
6. Parkinsonism-inducing neurotoxin, N-methyl-4phenyl-1,2,3,6-tetrahydropyridine: Uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity
7. Chronic Parkinsonism due to a product of meperidine-analog synthesis
8. Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenylpyridine, a metabolite of the neurotoxin 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
9. Sulphonate buffers affect the recovery of microtubule-associated proteins MAP1 and MAP2: Evidence that MAP1A promotes microtubule assembly
10. Mechanism of MPTP toxicity
11. Inhibition of mitochondrial NADH dehydrogenase by pyridine derivates and its possible relation to experimental and idiopathic parkinsonism
12. Alterations of cytoskeletal tau proteins of SH-SY5Y human neuroblastoma cells after exposure to MPTP
13. Equilibrium and kinetic analysis of microtubule assembly in the presence of guanosine diphosphate