메뉴 건너뛰기




Volumn 8, Issue 10, 2013, Pages

Association of 5-Methylcytosine and 5-Hydroxymethylcytosine with Mitochondrial DNA Content and Clinical and Biochemical Parameters in Hepatocellular Carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; 5 METHYLCYTOSINE; 5' NUCLEOTIDASE; ALANINE AMINOTRANSFERASE; ALBUMIN; ALKALINE PHOSPHATASE; ALPHA FETOPROTEIN; ASPARTATE AMINOTRANSFERASE; BILE ACID; BILIRUBIN; CA 125 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; CD30 LIGAND; CHOLINESTERASE; CREATININE; CYSTATIN C; GAMMA GLUTAMYLTRANSFERASE; GENOMIC DNA; GLOBULIN; GLUCOSE; MITOCHONDRIAL DNA; NITROGEN; PREALBUMIN; PROSTATE SPECIFIC ANTIGEN; RETINOL BINDING PROTEIN; UREA; URIC ACID;

EID: 84885443490     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0076967     Document Type: Article
Times cited : (11)

References (52)
  • 1
    • 33746539166 scopus 로고    scopus 로고
    • DNA precursor metabolism and genomic stability
    • Mathews CK, (2006) DNA precursor metabolism and genomic stability. FASEB J 20: 1300-1314.
    • (2006) FASEB J , vol.20 , pp. 1300-1314
    • Mathews, C.K.1
  • 2
    • 22044442733 scopus 로고    scopus 로고
    • Mitochondrial genome instability and mtDNA depletion in human cancers
    • Lee HC, Yin PH, Lin JC, Wu CC, Chen CY, et al. (2005) Mitochondrial genome instability and mtDNA depletion in human cancers. Ann N Y Acad Sci 1042: 109-122.
    • (2005) Ann N Y Acad Sci , vol.1042 , pp. 109-122
    • Lee, H.C.1    Yin, P.H.2    Lin, J.C.3    Wu, C.C.4    Chen, C.Y.5
  • 3
    • 70349823621 scopus 로고    scopus 로고
    • Mitochondrial DNA depletion promotes impaired oxidative status and adaptive resistance to apoptosis in T47D breast cancer cells
    • Yu M, Shi Y, Wei X, Yang Y, Zang F, et al. (2009) Mitochondrial DNA depletion promotes impaired oxidative status and adaptive resistance to apoptosis in T47D breast cancer cells. Eur J Cancer Prev 18: 445-457.
    • (2009) Eur J Cancer Prev , vol.18 , pp. 445-457
    • Yu, M.1    Shi, Y.2    Wei, X.3    Yang, Y.4    Zang, F.5
  • 4
    • 84865578152 scopus 로고    scopus 로고
    • Ethidium bromide as a marker of mtDNA replication in living cells
    • Villa AM, Fusi P, Pastori V, Amicarelli G, Pozzi C, et al. (2012) Ethidium bromide as a marker of mtDNA replication in living cells. J Biomed Opt 17: 046001.
    • (2012) J Biomed Opt , vol.17 , pp. 046001
    • Villa, A.M.1    Fusi, P.2    Pastori, V.3    Amicarelli, G.4    Pozzi, C.5
  • 5
    • 35448996907 scopus 로고    scopus 로고
    • Quantitation of DNA copy number in individual mitochondrial particles by capillary electrophoresis
    • Navratil M, Poe BG, Arriaga EA, (2007) Quantitation of DNA copy number in individual mitochondrial particles by capillary electrophoresis. Anal Chem 79: 7691-7699.
    • (2007) Anal Chem , vol.79 , pp. 7691-7699
    • Navratil, M.1    Poe, B.G.2    Arriaga, E.A.3
  • 6
    • 79960966530 scopus 로고    scopus 로고
    • A microfluidic system for fast detection of mitochondrial DNA deletion
    • Chang CM, Chiu LF, Wang PW, Shieh DB, Lee GB, (2011) A microfluidic system for fast detection of mitochondrial DNA deletion. Lab Chip 11: 2693-2700.
    • (2011) Lab Chip , vol.11 , pp. 2693-2700
    • Chang, C.M.1    Chiu, L.F.2    Wang, P.W.3    Shieh, D.B.4    Lee, G.B.5
  • 7
    • 84879009206 scopus 로고    scopus 로고
    • Is mitochondrial DNA content a potential biomarker of mitochondrial dysfunction?
    • Malik AN, Czajka A (2012) Is mitochondrial DNA content a potential biomarker of mitochondrial dysfunction? Mitochondrion. http://dx.doi.org/10.1016/j.mito.2012.10.011.
    • (2012) Mitochondrion
    • Malik, A.N.1    Czajka, A.2
  • 8
    • 84857393438 scopus 로고    scopus 로고
    • Association of mitochondrial DNA variations with lung cancer risk in a Han Chinese population from southwestern China
    • Zheng S, Qian P, Li F, Qian G, Wang C, et al. (2012) Association of mitochondrial DNA variations with lung cancer risk in a Han Chinese population from southwestern China. PLoS One 7: e31322.
    • (2012) PLoS One , vol.7
    • Zheng, S.1    Qian, P.2    Li, F.3    Qian, G.4    Wang, C.5
  • 9
    • 33645083995 scopus 로고    scopus 로고
    • Correlation between copy number of mitochondrial DNA and clinico-pathologic parameters of hepatocellular carcinoma
    • Yamada S, Nomoto S, Fujii T, Kaneko T, Takeda S, et al. (2006) Correlation between copy number of mitochondrial DNA and clinico-pathologic parameters of hepatocellular carcinoma. Eur J Surg Oncol 32: 303-307.
    • (2006) Eur J Surg Oncol , vol.32 , pp. 303-307
    • Yamada, S.1    Nomoto, S.2    Fujii, T.3    Kaneko, T.4    Takeda, S.5
  • 10
    • 80052524201 scopus 로고    scopus 로고
    • Mitochondrial DNA copy number and risk of gastric cancer: a report from the Shanghai Women's Health Study
    • Liao LM, Baccarelli A, Shu XO, Gao YT, Ji BT, et al. (2011) Mitochondrial DNA copy number and risk of gastric cancer: a report from the Shanghai Women's Health Study. Cancer Epidemiol Biomarkers Prev 20: 1944-1949.
    • (2011) Cancer Epidemiol Biomarkers Prev , vol.20 , pp. 1944-1949
    • Liao, L.M.1    Baccarelli, A.2    Shu, X.O.3    Gao, Y.T.4    Ji, B.T.5
  • 11
    • 84855275503 scopus 로고    scopus 로고
    • Mitochondrial DNA content varies with pathological characteristics of breast cancer
    • Bai RK, Chang J, Yeh KT, Lou MA, Lu JF, et al. (2011) Mitochondrial DNA content varies with pathological characteristics of breast cancer. J Oncol 2011: 496189.
    • (2011) J Oncol , vol.2011 , pp. 496189
    • Bai, R.K.1    Chang, J.2    Yeh, K.T.3    Lou, M.A.4    Lu, J.F.5
  • 12
    • 84856836080 scopus 로고    scopus 로고
    • Consumption of oxygen: a mitochondrial-generated progression signal of advanced cancer
    • Cook CC, Kim A, Terao S, Gotoh A, Higuchi M, (2012) Consumption of oxygen: a mitochondrial-generated progression signal of advanced cancer. Cell Death Dis 3: e258.
    • (2012) Cell Death Dis , vol.3
    • Cook, C.C.1    Kim, A.2    Terao, S.3    Gotoh, A.4    Higuchi, M.5
  • 13
    • 1542345767 scopus 로고    scopus 로고
    • Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma
    • Lee HC, Li SH, Lin JC, Wu CC, Yeh DC, et al. (2004) Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma. Mutat Res 547: 71-78.
    • (2004) Mutat Res , vol.547 , pp. 71-78
    • Lee, H.C.1    Li, S.H.2    Lin, J.C.3    Wu, C.C.4    Yeh, D.C.5
  • 14
    • 34547218569 scopus 로고    scopus 로고
    • Reduced mitochondrial DNA copy number is correlated with tumour progression and prognosis in Chinese breast cancer patients
    • Yu M, Zhou Y, Shi Y, Ning L, Yang Y, et al. (2007) Reduced mitochondrial DNA copy number is correlated with tumour progression and prognosis in Chinese breast cancer patients. IUBMB Life 59: 450-457.
    • (2007) IUBMB Life , vol.59 , pp. 450-457
    • Yu, M.1    Zhou, Y.2    Shi, Y.3    Ning, L.4    Yang, Y.5
  • 15
    • 11144222886 scopus 로고    scopus 로고
    • Mitochondrial DNA quantity increases with histopathologic grade in premalignant and malignant head and neck lesions
    • Kim MM, Clinger JD, Masayesva BG, Ha PK, Zahurak ML, et al. (2004) Mitochondrial DNA quantity increases with histopathologic grade in premalignant and malignant head and neck lesions. Clin Cancer Res 10: 8512-8515.
    • (2004) Clin Cancer Res , vol.10 , pp. 8512-8515
    • Kim, M.M.1    Clinger, J.D.2    Masayesva, B.G.3    Ha, P.K.4    Zahurak, M.L.5
  • 16
    • 84866939677 scopus 로고    scopus 로고
    • High mitochondrial DNA copy number and bioenergetic function are associated with tumour invasion of esophageal squamous cell carcinoma cell lines
    • Lin CS, Lee HT, Lee SY, Shen YA, Wang LS, et al. (2012) High mitochondrial DNA copy number and bioenergetic function are associated with tumour invasion of esophageal squamous cell carcinoma cell lines. Int J Mol Sci 13: 11228-11246.
    • (2012) Int J Mol Sci , vol.13 , pp. 11228-11246
    • Lin, C.S.1    Lee, H.T.2    Lee, S.Y.3    Shen, Y.A.4    Wang, L.S.5
  • 17
    • 79956330964 scopus 로고    scopus 로고
    • CpG islands and the regulation of transcription
    • Deaton AM, Bird A, (2011) CpG islands and the regulation of transcription. Genes Dev 25: 1010-1022.
    • (2011) Genes Dev , vol.25 , pp. 1010-1022
    • Deaton, A.M.1    Bird, A.2
  • 18
    • 80052461558 scopus 로고    scopus 로고
    • Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
    • Ito S, Shen L, Dai Q, Wu SC, Collins LB, et al. (2011) Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science 333: 1300-1303.
    • (2011) Science , vol.333 , pp. 1300-1303
    • Ito, S.1    Shen, L.2    Dai, Q.3    Wu, S.C.4    Collins, L.B.5
  • 19
    • 1042278765 scopus 로고    scopus 로고
    • The history of cancer epigenetics
    • Feinberg AP, Tycko B, (2004) The history of cancer epigenetics. Nat Rev Cancer 4: 143-153.
    • (2004) Nat Rev Cancer , vol.4 , pp. 143-153
    • Feinberg, A.P.1    Tycko, B.2
  • 20
    • 22844457491 scopus 로고    scopus 로고
    • DNA methylation and human disease
    • Robertson KD, (2005) DNA methylation and human disease. Nat Rev Genet 6: 597-610.
    • (2005) Nat Rev Genet , vol.6 , pp. 597-610
    • Robertson, K.D.1
  • 21
    • 84876944890 scopus 로고    scopus 로고
    • Quantification of 5-methylcytosine and 5-hydroxymethylcytosine in genomic DNA from hepatocellular carcinoma tissues by capillary hydrophilic-interaction liquid chromatography/quadrupole TOF mass spectrometry
    • Chen ML, Shen F, Huang W, Qi JH, Wang Y, et al. (2013) Quantification of 5-methylcytosine and 5-hydroxymethylcytosine in genomic DNA from hepatocellular carcinoma tissues by capillary hydrophilic-interaction liquid chromatography/quadrupole TOF mass spectrometry. Clin Chem 59: 824-832.
    • (2013) Clin Chem , vol.59 , pp. 824-832
    • Chen, M.L.1    Shen, F.2    Huang, W.3    Qi, J.H.4    Wang, Y.5
  • 22
    • 16544395591 scopus 로고    scopus 로고
    • DNA methylation and cancer
    • Das PM, Singal R, (2004) DNA methylation and cancer. J Clin Oncol 22: 4632-4642.
    • (2004) J Clin Oncol , vol.22 , pp. 4632-4642
    • Das, P.M.1    Singal, R.2
  • 23
    • 79955779160 scopus 로고    scopus 로고
    • Repetitive element hypomethylation in blood leukocyte DNA and cancer incidence, prevalence, and mortality in elderly individuals: the Normative Aging Study
    • Zhu ZZ, Sparrow D, Hou L, Tarantini L, Bollati V, et al. (2011) Repetitive element hypomethylation in blood leukocyte DNA and cancer incidence, prevalence, and mortality in elderly individuals: the Normative Aging Study. Cancer Causes Control 22: 437-447.
    • (2011) Cancer Causes Control , vol.22 , pp. 437-447
    • Zhu, Z.Z.1    Sparrow, D.2    Hou, L.3    Tarantini, L.4    Bollati, V.5
  • 24
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • Esteller M, (2008) Epigenetics in cancer. N Engl J Med 358: 1148-1159.
    • (2008) N Engl J Med , vol.358 , pp. 1148-1159
    • Esteller, M.1
  • 25
    • 0021368041 scopus 로고
    • Hypomethylation of hepatic nuclear DNA in rats fed with a carcinogenic methyl-deficient diet
    • Wilson MJ, Shivapurkar N, Poirier LA, (1984) Hypomethylation of hepatic nuclear DNA in rats fed with a carcinogenic methyl-deficient diet. Biochem J 218: 987-990.
    • (1984) Biochem J , vol.218 , pp. 987-990
    • Wilson, M.J.1    Shivapurkar, N.2    Poirier, L.A.3
  • 26
    • 0026721149 scopus 로고
    • Production of thyroid tumours in mice by demethylating agents
    • Thomas GA, Williams ED, (1992) Production of thyroid tumours in mice by demethylating agents. Carcinogenesis 13: 1039-1042.
    • (1992) Carcinogenesis , vol.13 , pp. 1039-1042
    • Thomas, G.A.1    Williams, E.D.2
  • 28
    • 0038523843 scopus 로고    scopus 로고
    • Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study
    • Pufulete M, Al-Ghnaniem R, Leather AJ, Appleby P, Gout S, et al. (2003) Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study. Gastroenterology 124: 1240-1248.
    • (2003) Gastroenterology , vol.124 , pp. 1240-1248
    • Pufulete, M.1    Al-Ghnaniem, R.2    Leather, A.J.3    Appleby, P.4    Gout, S.5
  • 29
    • 37349088614 scopus 로고    scopus 로고
    • Genomic methylation of leukocyte DNA in relation to colorectal adenoma among asymptomatic women
    • Lim U, Flood A, Choi SW, Albanes D, Cross AJ, et al. (2008) Genomic methylation of leukocyte DNA in relation to colorectal adenoma among asymptomatic women. Gastroenterology 134: 47-55.
    • (2008) Gastroenterology , vol.134 , pp. 47-55
    • Lim, U.1    Flood, A.2    Choi, S.W.3    Albanes, D.4    Cross, A.J.5
  • 30
    • 84861627818 scopus 로고    scopus 로고
    • Correlation between increased ND2 expression and demethylated displacement loop of mtDNA in colorectal cancer
    • Feng S, Xiong L, Ji Z, Cheng W, Yang H, (2012) Correlation between increased ND2 expression and demethylated displacement loop of mtDNA in colorectal cancer. Mol Med Rep 6: 125-130.
    • (2012) Mol Med Rep , vol.6 , pp. 125-130
    • Feng, S.1    Xiong, L.2    Ji, Z.3    Cheng, W.4    Yang, H.5
  • 31
    • 79953185821 scopus 로고    scopus 로고
    • Real-time quantitative PCR analysis of mitochondrial DNA content
    • Chapter 19: Unit 19 17
    • Venegas V, Wang J, Dimmock D, Wong LJ (2011) Real-time quantitative PCR analysis of mitochondrial DNA content. Curr Protoc Hum Genet Chapter 19: Unit 19 17.
    • (2011) Curr Protoc Hum Genet
    • Venegas, V.1    Wang, J.2    Dimmock, D.3    Wong, L.J.4
  • 32
    • 77649212939 scopus 로고    scopus 로고
    • A practical approach to RT-qPCR-Publishing data that conform to the MIQE guidelines
    • Taylor S, Wakem M, Dijkman G, Alsarraj M, Nguyen M, (2010) A practical approach to RT-qPCR-Publishing data that conform to the MIQE guidelines. Methods 50: S1-5.
    • (2010) Methods , vol.50
    • Taylor, S.1    Wakem, M.2    Dijkman, G.3    Alsarraj, M.4    Nguyen, M.5
  • 33
    • 0035109346 scopus 로고    scopus 로고
    • Mitochondrial genome instability in human cancers
    • Bianchi NO, Bianchi MS, Richard SM, (2001) Mitochondrial genome instability in human cancers. Mutat Res 488: 9-23.
    • (2001) Mutat Res , vol.488 , pp. 9-23
    • Bianchi, N.O.1    Bianchi, M.S.2    Richard, S.M.3
  • 34
    • 32544433582 scopus 로고    scopus 로고
    • Rate of gene transfer from mitochondria to nucleus: effects of cytoplasmic inheritance system and intensity of intracellular competition
    • Yamauchi A, (2005) Rate of gene transfer from mitochondria to nucleus: effects of cytoplasmic inheritance system and intensity of intracellular competition. Genetics 171: 1387-1396.
    • (2005) Genetics , vol.171 , pp. 1387-1396
    • Yamauchi, A.1
  • 35
    • 0030479894 scopus 로고    scopus 로고
    • Multiple independent transpositions of mitochondrial DNA control region sequences to the nucleus
    • Sorenson MD, Fleischer RC, (1996) Multiple independent transpositions of mitochondrial DNA control region sequences to the nucleus. Proc Natl Acad Sci U S A 93: 15239-15243.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 15239-15243
    • Sorenson, M.D.1    Fleischer, R.C.2
  • 37
    • 84873020277 scopus 로고    scopus 로고
    • Pathogenic mechanisms in HBV- and HCV-associated hepatocellular carcinoma
    • Arzumanyan A, Reis HM, Feitelson MA, (2013) Pathogenic mechanisms in HBV- and HCV-associated hepatocellular carcinoma. Nat Rev Cancer 13: 123-135.
    • (2013) Nat Rev Cancer , vol.13 , pp. 123-135
    • Arzumanyan, A.1    Reis, H.M.2    Feitelson, M.A.3
  • 38
    • 84878888076 scopus 로고    scopus 로고
    • Mitochondrial genetics
    • Chinnery PF, Hudson G, (2013) Mitochondrial genetics. Br Med Bull 106: 135-159.
    • (2013) Br Med Bull , vol.106 , pp. 135-159
    • Chinnery, P.F.1    Hudson, G.2
  • 39
    • 34447303791 scopus 로고    scopus 로고
    • The expression of polymerase gamma and mitochondrial transcription factor A and the regulation of mitochondrial DNA content in mature human sperm
    • Amaral A, Ramalho-Santos J, St John JC, (2007) The expression of polymerase gamma and mitochondrial transcription factor A and the regulation of mitochondrial DNA content in mature human sperm. Hum Reprod 22: 1585-1596.
    • (2007) Hum Reprod , vol.22 , pp. 1585-1596
    • Amaral, A.1    Ramalho-Santos, J.2    St John, J.C.3
  • 40
    • 84869054109 scopus 로고    scopus 로고
    • Mitochondrial DNA copy number is regulated in a tissue specific manner by DNA methylation of the nuclear-encoded DNA polymerase gamma A. Nucleic Acids Res
    • Kelly RD, Mahmud A, McKenzie M, Trounce IA, St John JC, (2012) Mitochondrial DNA copy number is regulated in a tissue specific manner by DNA methylation of the nuclear-encoded DNA polymerase gamma A. Nucleic Acids Res. 40: 10124-10138.
    • (2012) , vol.40 , pp. 10124-10138
    • Kelly, R.D.1    Mahmud, A.2    McKenzie, M.3    Trounce, I.A.4    St John, J.C.5
  • 41
    • 0346095167 scopus 로고    scopus 로고
    • In vitro methylation of nuclear respiratory factor-1 binding site suppresses the promoter activity of mitochondrial transcription factor A. Biochem Biophys Res Commun
    • Choi YS, Kim S, Kyu Lee H, Lee KU, Pak YK, (2004) In vitro methylation of nuclear respiratory factor-1 binding site suppresses the promoter activity of mitochondrial transcription factor A. Biochem Biophys Res Commun. 314: 118-122.
    • (2004) , vol.314 , pp. 118-122
    • Choi, Y.S.1    Kim, S.2    Kyu Lee, H.3    Lee, K.U.4    Pak, Y.K.5
  • 42
    • 69149087790 scopus 로고    scopus 로고
    • Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density
    • Barrès R, Osler ME, Yan J, Rune A, Fritz T, et al. (2009) Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density. Cell Metab 10: 189-198.
    • (2009) Cell Metab , vol.10 , pp. 189-198
    • Barrès, R.1    Osler, M.E.2    Yan, J.3    Rune, A.4    Fritz, T.5
  • 43
    • 79952749156 scopus 로고    scopus 로고
    • DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria
    • Shock LS, Thakkar PV, Peterson EJ, Moran RG, Taylor SM, (2011) DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria. Proc Natl Acad Sci U S A 108: 3630-3635.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 3630-3635
    • Shock, L.S.1    Thakkar, P.V.2    Peterson, E.J.3    Moran, R.G.4    Taylor, S.M.5
  • 44
    • 84863984782 scopus 로고    scopus 로고
    • Methyl donor deficiency impairs fatty acid oxidation through PGC-1alpha hypomethylation and decreased ER-alpha, ERR-alpha, and HNF-4alpha in the rat liver
    • Pooya S, Blaise S, Moreno Garcia M, Giudicelli J, Alberto JM, et al. (2012) Methyl donor deficiency impairs fatty acid oxidation through PGC-1alpha hypomethylation and decreased ER-alpha, ERR-alpha, and HNF-4alpha in the rat liver. J Hepatol 57: 344-351.
    • (2012) J Hepatol , vol.57 , pp. 344-351
    • Pooya, S.1    Blaise, S.2    Moreno Garcia, M.3    Giudicelli, J.4    Alberto, J.M.5
  • 45
    • 77956189495 scopus 로고    scopus 로고
    • Role of Tet proteins in 5 mC to 5 hmC conversion, ES-cell self-renewal and inner cell mass specification
    • Ito S, D'Alessio AC, Taranova OV, Hong K, Sowers LC, et al. (2010) Role of Tet proteins in 5 mC to 5 hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 466: 1129-1133.
    • (2010) Nature , vol.466 , pp. 1129-1133
    • Ito, S.1    D'Alessio, A.C.2    Taranova, O.V.3    Hong, K.4    Sowers, L.C.5
  • 46
    • 27844535385 scopus 로고    scopus 로고
    • Protein import into mitochondria
    • Mokranjac D, Neupert W, (2005) Protein import into mitochondria. Biochem Soc Trans 33: 1019-1023.
    • (2005) Biochem Soc Trans , vol.33 , pp. 1019-1023
    • Mokranjac, D.1    Neupert, W.2
  • 47
    • 77954371509 scopus 로고    scopus 로고
    • Quantitative evaluation of the mitochondrial DNA depletion syndrome
    • Dimmock D, Tang LY, Schmitt ES, Wong LJ, (2010) Quantitative evaluation of the mitochondrial DNA depletion syndrome. Clin Chem 56: 1119-1127.
    • (2010) Clin Chem , vol.56 , pp. 1119-1127
    • Dimmock, D.1    Tang, L.Y.2    Schmitt, E.S.3    Wong, L.J.4
  • 48
    • 79960422032 scopus 로고    scopus 로고
    • Association of mitochondrial DNA content in peripheral blood leukocyte with hepatitis B virus-related hepaatocellular carcinoma in a Chinese Han population
    • Zhao S, Yang Y, Liu J, Liu H, Ge N, et al. (2011) Association of mitochondrial DNA content in peripheral blood leukocyte with hepatitis B virus-related hepaatocellular carcinoma in a Chinese Han population. Cancer Sci 102: 1553-1558.
    • (2011) Cancer Sci , vol.102 , pp. 1553-1558
    • Zhao, S.1    Yang, Y.2    Liu, J.3    Liu, H.4    Ge, N.5
  • 49
    • 84867728046 scopus 로고    scopus 로고
    • Hepatocellular carcinoma risk prediction model for the general population: the predictive power of transaminases
    • Wen CP, Lin J, Yang YC, Tsai MK, Tsao CK, et al. (2012) Hepatocellular carcinoma risk prediction model for the general population: the predictive power of transaminases. J Natl Cancer Inst 104: 1599-1611.
    • (2012) J Natl Cancer Inst , vol.104 , pp. 1599-1611
    • Wen, C.P.1    Lin, J.2    Yang, Y.C.3    Tsai, M.K.4    Tsao, C.K.5
  • 50
    • 84868122238 scopus 로고    scopus 로고
    • Comprehensive analysis of common serum liver enzymes as prospective predictors of hepatocellular carcinoma in HBV patients
    • Hann HW, Wan S, Myers RE, Hann RS, Xing J, et al. (2012) Comprehensive analysis of common serum liver enzymes as prospective predictors of hepatocellular carcinoma in HBV patients. PLoS One 7: e47687.
    • (2012) PLoS One , vol.7
    • Hann, H.W.1    Wan, S.2    Myers, R.E.3    Hann, R.S.4    Xing, J.5
  • 51
    • 84877336241 scopus 로고    scopus 로고
    • Decrease of 5-Hydroxymethylcytosine Is Associated with Progression of Hepatocellular Carcinoma through Downregulation of TET1
    • Liu C, Liu L, Chen X, Shen J, Shan J, et al. (2013) Decrease of 5-Hydroxymethylcytosine Is Associated with Progression of Hepatocellular Carcinoma through Downregulation of TET1. PLoS One 8: e62828.
    • (2013) PLoS One , vol.8
    • Liu, C.1    Liu, L.2    Chen, X.3    Shen, J.4    Shan, J.5
  • 52
    • 0037029073 scopus 로고    scopus 로고
    • Depletion of mitochondrial DNA in the skeletal muscle of two cirrhotic patients with severe asthenia
    • Pesce V, Cormio A, Marangi LC, Guglielmi FW, Lezza AM, et al. (2002) Depletion of mitochondrial DNA in the skeletal muscle of two cirrhotic patients with severe asthenia. Gene 286: 143-148.
    • (2002) Gene , vol.286 , pp. 143-148
    • Pesce, V.1    Cormio, A.2    Marangi, L.C.3    Guglielmi, F.W.4    Lezza, A.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.