Identification and analysis of absorbed components and their metabolites in rat plasma and tissues after oral administration of 'Ershiwuwei Shanhu' pill extracts by UPLC-DAD/Q-TOF-MS

Journal of Ethnopharmacology

Volumn 150, Issue 1, 2013, Pages 324-338

  Ying, Xuhui ^a,b   Liu, Mingying ^b,c   Liang, Qionglin ^b   Jiang, Min ^a   Wang, Yiming ^b   Huang, Fukai ^d   Xie, Yuanyuan ^b   Shao, Jie ^d   Bai, Gang ^a   Luo, Guoan ^a,b  

^a NANKAI UNIVERSITY   (China)

^b TSINGHUA UNIVERSITY   (China)

^c JIANGXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^d BeijingTibetan and Ethnic Medicine Hospital   (China)

Author keywords

'Ershiwuwei Shanhu' pill; Absorption; Metabolism; Plasma pharmacochemistry; Traditional Tibetan medicine; UPLC DAD Q TOF MS

Indexed keywords

14 ACETYLTALATISAMINE; ACORAMONE; ALPHA ASARONE; AMAROGENTIN; CAFFEIC ACID; CHASMANINE; CORILAGIN; COSTUNOLIDE; CROCIN II; DECUSSATIN; DEOXYACONITINE; DRUG METABOLITE; ELLAGIC ACID; ERSHIWUWEI SHANHU EXTRACT; FORMONONETIN; GALLIC ACID; GLYCYRRHIZIC ACID; HYPERIN; ISOBOLDINE; LIQUIRITIN; LIQUIRITIN APIOSIDE; LUTEOLIN; MANGIFERIN; PLANT MEDICINAL PRODUCT; QUERCETIN; RETICULINE; SCUTELLARIN; TALATISAMINE; TERMINALIA CHEBULA EXTRACT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; BRAIN; CONTROLLED STUDY; CROCUS SATIVUS; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG EXCRETION; DRUG IDENTIFICATION; DRUG LIVER LEVEL; DRUG METABOLISM; DRUG STRUCTURE; HEART; KIDNEY; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PHARMACOLOGY; PHYSICAL CHEMISTRY; RAT; SAFFLOWER; TERMINALIA CHEBULA; TIBETAN MEDICINE; TRADITIONAL MEDICINE; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

RATTUS;

'ERSHIWUWEI SHANHU' PILL; ABSORPTION; METABOLISM; PLASMA PHARMACOCHEMISTRY; TRADITIONAL TIBETAN MEDICINE; UPLC-DAD/Q-TOF-MS;

ANIMALS; BRAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; KIDNEY; LIVER; MALE; MASS SPECTROMETRY; MEDICINE, TIBETAN TRADITIONAL; MYOCARDIUM; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84885423613     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.08.046     Document Type: Article

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