Plasma pharmacochemistry based approach to screening potential bioactive components in Huang-Lian-Jie-Du-Tang using high performance liquid chromatography coupled with mass spectrometric detection

Journal of Ethnopharmacology

Volumn 141, Issue 2, 2012, Pages 728-735

  Hu, Yaohua ^a   Jiang, Peng ^a   Wang, Shuping ^a   Yan, Shikai ^b   Xiang, Li ^a   Zhang, Weidong ^a,b   Liu, Runhui ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Huang Lian Jie Du Tang; LC MS; Metabolites; Plasma pharmacochemistry; Traditional Chinese medicine

Indexed keywords

5,7 DIHYDROXY 6,8 DIMETHOXY FLAVONE 7 O GLUCURONIDE; BAICALIN; BERBERINE; BERBERUBINE; CHLOROGENIC ACID; CHRYSIN 6 C ARABINOSYL 8 C GLUCOSIDE; CHRYSIN 6 C GLUCOSYL 8 C ARABONOSIDE; COLUMBAMINE; EPIBERBERINE; GARDENOSIDE B; GENIPINGENTIOBIOSIDE; HUANG LIAN JIE DU TANG EXTRACT; JASMINOIDIN; JATRORRHIZINE; LOTUSINE; MAGNOFLORINE; OBAKULACTONE; OROXYLINA 7 O GLUCURONIDE; PALMATINE; PHELLODENDRINE; PLANT EXTRACT; TRIHYDROXY 8 METHOXY FLAVONE 7 O GLUCURONIDE; UNCLASSIFIED DRUG; WOGONIN; WOGONOSIDE;

ANIMAL EXPERIMENT; ARTICLE; CHEMICAL PROCEDURES; CONTROLLED STUDY; DRUG SCREENING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MEDICINAL PLANT; METABOLITE; METHODOLOGY; NONHUMAN; PLASMA PHARMACOCHEMISTRY; RAT; RELIABILITY; TANDEM MASS SPECTROMETRY;

ADMINISTRATION, ORAL; ANIMALS; BIOTRANSFORMATION; BLOOD; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; MALE; MEDICINE, CHINESE TRADITIONAL; PLANTS, MEDICINAL; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 84861190675     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.08.011     Document Type: Article

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