Baicalin can scavenge peroxynitrite and ameliorate endogenous peroxynitrite-mediated neurotoxicity in cerebral ischemia-reperfusion injury

Journal of Ethnopharmacology

Volumn 150, Issue 1, 2013, Pages 116-124

  Xu, Mingjing ^a,b   Chen, Xingmiao ^a,b   Gu, Yong ^a,b   Peng, Tao ^b   Yang, Dan ^b   Chang, Raymond Chuen Chuen ^b,c   So, Kwok Fai ^c   Liu, Kejian ^d   Shen, Jiangang ^a  

^a THE UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

^d UNIVERSITY OF NEW MEXICO   (United States)

Author keywords

Baicalin; Cerebral ischemia; Peroxynitrite

Indexed keywords

BAICALIN; NEUROPROTECTIVE AGENT; NITRIC OXIDE; PEROXYNITRITE; SCAVENGER;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; CELL VIABILITY; DRUG EFFECT; ELECTRON SPIN RESONANCE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; MASS SPECTROMETRY; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROBLASTOMA CELL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; RAT; REOXYGENATION; REPERFUSION INJURY; SPIN TRAPPING;

RATTUS; SCUTELLARIA BAICALENSIS;

3-(4,5-DIMETHYLTHIAZOL-2-YL)-2,5-DIPHENYLTETRAZOLIUM BROMIDE; 3-MORPHOLINOSYDNONIMINE; 3-NITROTYROSINE; 3-NT; 4′,6-DIAMIDINO-2-PHENYLINDOLE; 5-TERT-BUTOXYCARBONYL 5-METHYL-1-PYRROLINE N-OXIDE; BAICALIN; BBB; BLOOD BRAIN BARRIER; BMPO; CEREBRAL ISCHEMIA; DAPI; DIETHYLENETRIAMINE PENTAACETIC ACID; DIMETHYL SULFOXIDE; DMSO; DTPA; HX; HYPOXANTHINE; MATRIX METALLOPROTEINASES; MCAO; MGD; MIDDLE CEREBRAL ARTERY OCCLUSION; MMPS; MTT; N-METHYL-D-GLUTAMINE-DITHIOCARBAMATE; OGD/RO; OXYGEN GLUCOSE DEPRIVATION PLUS REOXYGENATION; PDC; PEROXYNITRITE; PEROXYNITRITE DECOMPOSITION CATALYST; REACTIVE OXYGEN SPECIES; ROS; SIN-1; TERMINAL DEOXYNUCLEOTIDYL TRANSFERASE-MEDIATED DUTP NICK END LABELING.; TRIPHENYL TETRAZOLIUM CHLORIDE; TTC; TUNEL; XANTHINE OXIDASE; XO;

ANIMALS; ANTIOXIDANTS; BRAIN; BRAIN ISCHEMIA; CELL LINE, TUMOR; FLAVONOIDS; HUMANS; MALE; NEUROPROTECTIVE AGENTS; NITRIC OXIDE; PEROXYNITROUS ACID; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; SUPEROXIDES;

EID: 84885421083     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.08.020     Document Type: Article

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