Complexation with organometallic ruthenium pharmacophores enhances the ability of 4-anilinoquinazolines inducing apoptosis

Chemical Communications

Volumn 49, Issue 87, 2013, Pages 10224-10226

  Zheng, Wei ^a,b   Luo, Qun ^a,b   Lin, Yu ^a,b   Zhao, Yao ^a,b   Wang, Xiuli ^c   Du, Zhifeng ^a,b   Hao, Xiang ^a   Yu, Yang ^c   Lü, Shuang ^a,b   Ji, Liyun ^a,b   Li, Xianchan ^a,b   Yang, Ling ^c   Wang, Fuyi ^a,b  

^a PEKING UNIVERSITY   (China)

^b INSTITUTE OF CHEMISTRY   (China)

^c DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; GEFITINIB; QUINAZOLINE DERIVATIVE; RUTHENIUM;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; COMPLEX FORMATION; FLUORESCENCE MICROSCOPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROLYSIS; IC 50; MASS SPECTROMETRY; PHARMACOPHORE; STEREOSPECIFICITY; ULTRAVIOLET SPECTROSCOPY; X RAY DIFFRACTION;

ANILINE COMPOUNDS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL PROLIFERATION; CRYSTALLOGRAPHY, X-RAY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; HYDROLYSIS; MCF-7 CELLS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RUTHENIUM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84885397044     PISSN: 13597345     EISSN: 1364548X     Source Type: Journal    
DOI: 10.1039/c3cc43000f     Document Type: Article

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