-
1
-
-
0002855171
-
New tumor-inhibiting ruthenium complexes
-
B. Keppler VCH Verlagsgesellschaft, VCH Publishers Weinheim, NY
-
B.K. Keppler, K.-G. Lipponer, B. Stenzel, and F. Kratz New tumor-inhibiting ruthenium complexes B Keppler Metal Complexes in Cancer Chemotherapy 1993 VCH Verlagsgesellschaft, VCH Publishers Weinheim, NY 187 220
-
(1993)
Metal Complexes in Cancer Chemotherapy
, pp. 187-220
-
-
Keppler, B.K.1
Lipponer, K.-G.2
Stenzel, B.3
Kratz, F.4
-
2
-
-
0042948708
-
Ruthenium metallopharmaceuticals
-
M.J. Clarke Ruthenium metallopharmaceuticals Coord. Chem. Rev. 236 2003 209 233
-
(2003)
Coord. Chem. Rev.
, vol.236
, pp. 209-233
-
-
Clarke, M.J.1
-
3
-
-
0035950152
-
Inhibition of cancer cell growth by ruthenium(II) arene complexes
-
R.E. Morris, R.E. Aird, P.D. Murdoch, H.M. Chen, J. Cummings, N.D. Hughes, S. Parsons, A. Parkin, G. Boyd, and D.I. Jodrell Inhibition of cancer cell growth by ruthenium(II) arene complexes J. Med. Chem. 44 2001 3616 3621
-
(2001)
J. Med. Chem.
, vol.44
, pp. 3616-3621
-
-
Morris, R.E.1
Aird, R.E.2
Murdoch, P.D.3
Chen, H.M.4
Cummings, J.5
Hughes, N.D.6
Parsons, S.7
Parkin, A.8
Boyd, G.9
Jodrell, D.I.10
-
4
-
-
0037141471
-
In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer
-
R. Aird, J. Cummings, A. Ritchie, M. Muir, R. Morris, H. Chen, P. Sadler, and D. Jodrell In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer Br. J. Cancer 86 2002 1652 1657
-
(2002)
Br. J. Cancer
, vol.86
, pp. 1652-1657
-
-
Aird, R.1
Cummings, J.2
Ritchie, A.3
Muir, M.4
Morris, R.5
Chen, H.6
Sadler, P.7
Jodrell, D.8
-
5
-
-
0034243140
-
Ruthenium-based compounds and tumour growth control (Review)
-
G. Sava, and A. Bergamo Ruthenium-based compounds and tumour growth control (Review) Int. J. Oncol. 17 2000 353 365
-
(2000)
Int. J. Oncol.
, vol.17
, pp. 353-365
-
-
Sava, G.1
Bergamo, A.2
-
6
-
-
0347624091
-
Kinetics of aquation and anation of ruthenium(II) arene anticancer complexes, acidity and X-ray structures of aqua adducts
-
F. Wang, H. Chen, S. Parsons, I.D.H. Oswald, J.E. Davidson, and P.J. Sadler Kinetics of aquation and anation of ruthenium(II) arene anticancer complexes, acidity and X-ray structures of aqua adducts Chem. Eur. J 9 2003 5810 5820
-
(2003)
Chem. Eur. J
, vol.9
, pp. 5810-5820
-
-
Wang, F.1
Chen, H.2
Parsons, S.3
Oswald, I.D.H.4
Davidson, J.E.5
Sadler, P.J.6
-
7
-
-
0037181357
-
Organometallic ruthenium(II) diamine anticancer complexes: Arene-nucleobase stacking and stereospecific hydrogen-bonding in guanine adducts
-
H.M. Chen, J.A. Parkinson, S. Parsons, R.A. Coxall, R.O. Gould, and P.J. Sadler Organometallic ruthenium(II) diamine anticancer complexes: arene-nucleobase stacking and stereospecific hydrogen-bonding in guanine adducts J. Am. Chem. Soc. 124 2002 3064 3082
-
(2002)
J. Am. Chem. Soc.
, vol.124
, pp. 3064-3082
-
-
Chen, H.M.1
Parkinson, J.A.2
Parsons, S.3
Coxall, R.A.4
Gould, R.O.5
Sadler, P.J.6
-
8
-
-
0141706614
-
DNA interactions of monofunctional organometallic ruthenium(II) antitumor complexes in cell-free media
-
O. Novakova, H. Chen, O. Vrana, A. Rodger, P.J. Sadler, and V. Brabec DNA interactions of monofunctional organometallic ruthenium(II) antitumor complexes in cell-free media Biochemistry 42 2003 11544 11554
-
(2003)
Biochemistry
, vol.42
, pp. 11544-11554
-
-
Novakova, O.1
Chen, H.2
Vrana, O.3
Rodger, A.4
Sadler, P.J.5
Brabec, V.6
-
9
-
-
0025382508
-
Chemical and photochemical probing of DNA complexes
-
P.E. Nielsen Chemical and photochemical probing of DNA complexes J. Mol. Recognit. 3 1990 1 24
-
(1990)
J. Mol. Recognit.
, vol.3
, pp. 1-24
-
-
Nielsen, P.E.1
-
10
-
-
0027485725
-
DNA conformational distortion produced by site-specific interstrand cross-link of trans-diamminedichloroplatinum(II)
-
V. Brabec, M. Sip, and M. Leng DNA conformational distortion produced by site-specific interstrand cross-link of trans-diamminedichloroplatinum(II) Biochemistry 32 1993 11676 11681
-
(1993)
Biochemistry
, vol.32
, pp. 11676-11681
-
-
Brabec, V.1
Sip, M.2
Leng, M.3
-
11
-
-
0034711943
-
DNA sequence context modulates the impact of a cisplatin 1,2-d(GpG) intrastrand cross-link an the conformational and thermodynamic properties of duplex DNA
-
D.S. Pilch, S.U. Dunham, E.R. Jamieson, S.J. Lippard, and K.J. Breslauer DNA sequence context modulates the impact of a cisplatin 1,2-d(GpG) intrastrand cross-link an the conformational and thermodynamic properties of duplex DNA J. Mol. Biol. 296 2000 803 812
-
(2000)
J. Mol. Biol.
, vol.296
, pp. 803-812
-
-
Pilch, D.S.1
Dunham, S.U.2
Jamieson, E.R.3
Lippard, S.J.4
Breslauer, K.J.5
-
12
-
-
0035873558
-
Thermodynamic properties of duplex DNA containing a site-specific d(GpG) intrastrand crosslink formed by an antitumor dinuclear platinum complex
-
C. Hofr, N. Farrell, and V. Brabec Thermodynamic properties of duplex DNA containing a site-specific d(GpG) intrastrand crosslink formed by an antitumor dinuclear platinum complex Nucleic Acids Res. 29 2001 2034 2040
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 2034-2040
-
-
Hofr, C.1
Farrell, N.2
Brabec, V.3
-
13
-
-
0034034773
-
DNA interactions of antitumor cisplatin analogs containing enantiomeric amine ligands
-
J. Malina, C. Hofr, L. Maresca, G. Natile, and V. Brabec DNA interactions of antitumor cisplatin analogs containing enantiomeric amine ligands Biophys. J. 78 2000 2008 2021
-
(2000)
Biophys. J.
, vol.78
, pp. 2008-2021
-
-
Malina, J.1
Hofr, C.2
Maresca, L.3
Natile, G.4
Brabec, V.5
-
14
-
-
0033614819
-
Enthalpy and heat capacity changes for formation of an oligomeric DNA duplex: Interpretation in terms of coupled processes of formation and association of single-stranded helices
-
J.A. Holbrook, M.W. Capp, R.M. Saecker, and M.T. Record Enthalpy and heat capacity changes for formation of an oligomeric DNA duplex: interpretation in terms of coupled processes of formation and association of single-stranded helices Biochemistry 38 1999 8409 8422
-
(1999)
Biochemistry
, vol.38
, pp. 8409-8422
-
-
Holbrook, J.A.1
Capp, M.W.2
Saecker, R.M.3
Record, M.T.4
-
15
-
-
0025080319
-
Effect of the antitumor drug cis-diamminedichloroplatinum(II) and related platinum complexes on eukaryotic DNA replication
-
W.J. Heiger-Bernays, J.M. Essigmann, and S.J. Lippard Effect of the antitumor drug cis-diamminedichloroplatinum(II) and related platinum complexes on eukaryotic DNA replication Biochemistry 29 1990 8461 8466
-
(1990)
Biochemistry
, vol.29
, pp. 8461-8466
-
-
Heiger-Bernays, W.J.1
Essigmann, J.M.2
Lippard, S.J.3
-
16
-
-
0037469136
-
3) (thiazole)]. Protein recognition and nucleotide excision repair of monofunctional adducts
-
3)(thiazole)]. Protein recognition and nucleotide excision repair of monofunctional adducts Biochemistry 42 2003 792 800
-
(2003)
Biochemistry
, vol.42
, pp. 792-800
-
-
Kasparkova, J.1
Novakova, O.2
Farrell, N.3
Brabec, V.4
-
17
-
-
0029783348
-
Repair of cisplatin-DNA adducts by the mammalian excision nuclease
-
D.B. Zamble, D. Mu, J.T. Reardon, A. Sancar, and S.J. Lippard Repair of cisplatin-DNA adducts by the mammalian excision nuclease Biochemistry 35 1996 10004 10013
-
(1996)
Biochemistry
, vol.35
, pp. 10004-10013
-
-
Zamble, D.B.1
Mu, D.2
Reardon, J.T.3
Sancar, A.4
Lippard, S.J.5
-
18
-
-
0033566758
-
Efficient nucleotide excision repair of cisplatin, oxaliplatin, and bis-aceto-ammine-dichloro-cyclohexylamine-platinum(IV) (JM216) platinum intrastrand DNA diadducts
-
J.T. Reardon, A. Vaisman, S.G. Chaney, and A. Sancar Efficient nucleotide excision repair of cisplatin, oxaliplatin, and bis-aceto-ammine-dichloro- cyclohexylamine-platinum(IV) (JM216) platinum intrastrand DNA diadducts Cancer Res. 59 1999 3968 3971
-
(1999)
Cancer Res.
, vol.59
, pp. 3968-3971
-
-
Reardon, J.T.1
Vaisman, A.2
Chaney, S.G.3
Sancar, A.4
-
19
-
-
0347481385
-
Activation of trans geometry in bifunctional mononuclear platinum complexes by a piperidine ligand: Mechanistic studies on antitumor action
-
J. Kasparkova, O. Novakova, V. Marini, Y. Najajreh, D. Gibson, J.-M. Perez, and V. Brabec Activation of trans geometry in bifunctional mononuclear platinum complexes by a piperidine ligand: mechanistic studies on antitumor action J. Biol. Chem. 278 2003 47516 47525
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 47516-47525
-
-
Kasparkova, J.1
Novakova, O.2
Marini, V.3
Najajreh, Y.4
Gibson, D.5
Perez, J.-M.6
Brabec, V.7
-
20
-
-
0035933825
-
Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair of DNA intrastrand cross-links of novel antitumor trinuclear platinum complex BBR3464
-
J. Zehnulova, J. Kasparkova, N. Farrell, and V. Brabec Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair of DNA intrastrand cross-links of novel antitumor trinuclear platinum complex BBR3464 J. Biol. Chem. 276 2001 22191 22199
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 22191-22199
-
-
Zehnulova, J.1
Kasparkova, J.2
Farrell, N.3
Brabec, V.4
-
22
-
-
0036357321
-
DNA modifications by antitumor platinum and ruthenium compounds: Their recognition and repair
-
K. Moldave Academic Press, Inc. San Diego
-
V. Brabec DNA modifications by antitumor platinum and ruthenium compounds: their recognition and repair K Moldave In Progress in Nucleic Acid Research and Molecular Biology, Volume 71 2002 Academic Press, Inc. San Diego 1 68
-
(2002)
In Progress in Nucleic Acid Research and Molecular Biology, Volume 71
, pp. 1-68
-
-
Brabec, V.1
-
23
-
-
0033258399
-
Physicochemical approaches to structural elucidation. Effects of 3,N4-ethenodeoxycytidine on duplex stability and energetics
-
B. Singer, H. Bartsch International Agency for Research on Cancer Lyon
-
G.E. Plum, C.A. Gelfand, and K.J. Breslauer Physicochemical approaches to structural elucidation. Effects of 3,N4-ethenodeoxycytidine on duplex stability and energetics B. Singer, H. Bartsch Exocyclic DNA Adducts in Mutagenesis and Carcinogenesis, Publication No. 150 1999 International Agency for Research on Cancer Lyon 169 177
-
(1999)
Exocyclic DNA Adducts in Mutagenesis and Carcinogenesis, Publication No. 150
, pp. 169-177
-
-
Plum, G.E.1
Gelfand, C.A.2
Breslauer, K.J.3
-
24
-
-
0024993904
-
Differential scanning calorimetric study of the effect of intercalators and other kinds of DNA-binding drugs on the stepwise melting of plasmid DNA
-
Y. Maeda, K. Nunomura, and E. Ohtsubo Differential scanning calorimetric study of the effect of intercalators and other kinds of DNA-binding drugs on the stepwise melting of plasmid DNA J. Mol. Biol. 215 1990 321 329
-
(1990)
J. Mol. Biol.
, vol.215
, pp. 321-329
-
-
Maeda, Y.1
Nunomura, K.2
Ohtsubo, E.3
-
25
-
-
0037026872
-
DNA melting in the presence of fluorescent intercalating oxazole yellow dyes measured with a gel-based assay
-
M.T. Bjorndal, and D.K. Fygenson DNA melting in the presence of fluorescent intercalating oxazole yellow dyes measured with a gel-based assay Biopolymers 65 2002 40 44
-
(2002)
Biopolymers
, vol.65
, pp. 40-44
-
-
Bjorndal, M.T.1
Fygenson, D.K.2
-
26
-
-
2542422438
-
Structure, recognition, and processing of cisplatin-DNA adducts
-
E.R. Jamieson, and S.J. Lippard Structure, recognition, and processing of cisplatin-DNA adducts Chem. Rev. 99 1999 2467 2498
-
(1999)
Chem. Rev.
, vol.99
, pp. 2467-2498
-
-
Jamieson, E.R.1
Lippard, S.J.2
-
27
-
-
0033578010
-
Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins
-
U.M. Ohndorf, M.A. Rould, Q. He, C.O. Pabo, and S.J. Lippard Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins Nature 399 1999 708 712
-
(1999)
Nature
, vol.399
, pp. 708-712
-
-
Ohndorf, U.M.1
Rould, M.A.2
He, Q.3
Pabo, C.O.4
Lippard, S.J.5
-
28
-
-
0036618858
-
Molecular aspects of resistance to antitumor platinum drugs
-
V. Brabec, and J. Kasparkova Molecular aspects of resistance to antitumor platinum drugs Drug Resist. Updat. 5 2002 147 161
-
(2002)
Drug Resist. Updat.
, vol.5
, pp. 147-161
-
-
Brabec, V.1
Kasparkova, J.2
-
29
-
-
0037073777
-
DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464. Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair
-
J. Kasparkova, J. Zehnulova, N. Farrell, and V. Brabec DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464. Conformation, recognition by high mobility group domain proteins, and nucleotide excision repair J. Biol. Chem. 277 2002 48076 48086
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 48076-48086
-
-
Kasparkova, J.1
Zehnulova, J.2
Farrell, N.3
Brabec, V.4
-
30
-
-
0036732039
-
Transcription-coupled nucleotide excision repair as a determinant of cisplatin sensitivity of human cells
-
T. Furuta, T. Ueda, G. Aune, A. Sarasin, K.H. Kraemer, and Y. Pommier Transcription-coupled nucleotide excision repair as a determinant of cisplatin sensitivity of human cells Cancer Res. 62 2002 4899 4902
-
(2002)
Cancer Res.
, vol.62
, pp. 4899-4902
-
-
Furuta, T.1
Ueda, T.2
Aune, G.3
Sarasin, A.4
Kraemer, K.H.5
Pommier, Y.6
-
31
-
-
0038661177
-
Nucleotide excision repair from site-specifically platinum-modified nucleosomes
-
D. Wang, R. Hara, G. Singh, A. Sancar, and S.J. Lippard Nucleotide excision repair from site-specifically platinum-modified nucleosomes Biochemistry 42 2003 6747 6753
-
(2003)
Biochemistry
, vol.42
, pp. 6747-6753
-
-
Wang, D.1
Hara, R.2
Singh, G.3
Sancar, A.4
Lippard, S.J.5
-
32
-
-
0037444279
-
Enhanced cisplatin cytotoxicity by disturbing the nucleotide excision repair pathway in ovarian cancer cell lines
-
M. Selvakumaran, D.A. Pisarcik, R. Bao, A.T. Yeung, and T.C. Hamilton Enhanced cisplatin cytotoxicity by disturbing the nucleotide excision repair pathway in ovarian cancer cell lines Cancer Res. 63 2003 1311 1316
-
(2003)
Cancer Res.
, vol.63
, pp. 1311-1316
-
-
Selvakumaran, M.1
Pisarcik, D.A.2
Bao, R.3
Yeung, A.T.4
Hamilton, T.C.5
-
33
-
-
0026992557
-
Sequence-dependent distortions induced in DNA by monofunctional platinum(II) binding
-
V. Brabec, J. Reedijk, and M. Leng Sequence-dependent distortions induced in DNA by monofunctional platinum(II) binding Biochemistry 31 1992 12397 12402
-
(1992)
Biochemistry
, vol.31
, pp. 12397-12402
-
-
Brabec, V.1
Reedijk, J.2
Leng, M.3
-
34
-
-
0027301069
-
DNA interstrand cross-links of trans-diamminedichloroplatinum(II) are preferentially formed between guanine and complementary cytosine residues
-
V. Brabec, and M. Leng DNA interstrand cross-links of trans-diamminedichloroplatinum(II) are preferentially formed between guanine and complementary cytosine residues Proc. Natl. Acad. Sci. USA 90 1993 5345 5349
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 5345-5349
-
-
Brabec, V.1
Leng, M.2
-
35
-
-
0030571001
-
Concentration and extinction coefficient determination for oligonucleotides and analogs using a general phosphate analysis
-
J.H. Murphy, and T.L. Trapane Concentration and extinction coefficient determination for oligonucleotides and analogs using a general phosphate analysis Anal. Biochem. 240 1996 273 282
-
(1996)
Anal. Biochem.
, vol.240
, pp. 273-282
-
-
Murphy, J.H.1
Trapane, T.L.2
-
36
-
-
0033515064
-
Interaction of DNA polymerase I (Klenow fragment) with DNA substrates containing extrahelical bases: Implications for proofreading of frameshift errors during DNA synthesis
-
W.C. Lam, E.J.C. Van der Schans, L.C. Sowers, and D.P. Millar Interaction of DNA polymerase I (Klenow fragment) with DNA substrates containing extrahelical bases: implications for proofreading of frameshift errors during DNA synthesis Biochemistry 38 1999 2661 2668
-
(1999)
Biochemistry
, vol.38
, pp. 2661-2668
-
-
Lam, W.C.1
Van Der Schans, E.J.C.2
Sowers, L.C.3
Millar, D.P.4
-
37
-
-
0035906661
-
Prokaryotic DNA polymerase I: Evolution, structure, and 'base flipping' mechanism for nucleotide selection
-
P.H. Patel, M. Suzuki, E. Adman, A. Shinkai, and L.A. Loeb Prokaryotic DNA polymerase I: evolution, structure, and 'base flipping' mechanism for nucleotide selection J. Mol. Biol. 308 2001 823 837
-
(2001)
J. Mol. Biol.
, vol.308
, pp. 823-837
-
-
Patel, P.H.1
Suzuki, M.2
Adman, E.3
Shinkai, A.4
Loeb, L.A.5
-
38
-
-
0036015846
-
Recognition of major DNA adducts of enantiomeric cisplatin analogs by HMG box proteins and nucleotide excision repair of these adducts
-
J. Malina, J. Kasparkova, G. Natile, and V. Brabec Recognition of major DNA adducts of enantiomeric cisplatin analogs by HMG box proteins and nucleotide excision repair of these adducts Chem. Biol. 9 2002 629 638
-
(2002)
Chem. Biol.
, vol.9
, pp. 629-638
-
-
Malina, J.1
Kasparkova, J.2
Natile, G.3
Brabec, V.4
|