-
1
-
-
0030022273
-
Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII
-
Kentrup H, Becker W, Heukelbach J, Wilmes A, Schurmann A, et al. (1996) Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII. J Biol Chem 271: 3488-3495.
-
(1996)
J Biol Chem
, vol.271
, pp. 3488-3495
-
-
Kentrup, H.1
Becker, W.2
Heukelbach, J.3
Wilmes, A.4
Schurmann, A.5
-
2
-
-
20444387985
-
Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs
-
Lochhead PA, Sibbet G, Morrice N, Cleghon V, (2005) Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs. Cell 121: 925-936.
-
(2005)
Cell
, vol.121
, pp. 925-936
-
-
Lochhead, P.A.1
Sibbet, G.2
Morrice, N.3
Cleghon, V.4
-
3
-
-
84874332563
-
HIPK2 kinase activity depends on cis-autophosphorylation of its activation loop
-
Saul VV, de la Vega L, Milanovic M, Kruger M, Braun T, et al. (2012) HIPK2 kinase activity depends on cis-autophosphorylation of its activation loop. J Mol Cell Biol 5: 27-38.
-
(2012)
J Mol Cell Biol
, vol.5
, pp. 27-38
-
-
Saul, V.V.1
de la Vega, L.2
Milanovic, M.3
Kruger, M.4
Braun, T.5
-
4
-
-
84855326537
-
Deep evolutionary conservation of an intramolecular protein kinase activation mechanism
-
Han J, Miranda-Saavedra D, Luebbering N, Singh A, Sibbet G, et al. (2012) Deep evolutionary conservation of an intramolecular protein kinase activation mechanism. PloS One 7: e29702.
-
(2012)
PloS One
, vol.7
-
-
Han, J.1
Miranda-Saavedra, D.2
Luebbering, N.3
Singh, A.4
Sibbet, G.5
-
5
-
-
79551647919
-
DYRK family of protein kinases: evolutionary relationships, biochemical properties, and functional roles
-
Aranda S, Laguna A, de la Luna S, (2011) DYRK family of protein kinases: evolutionary relationships, biochemical properties, and functional roles. FASEB J 25: 449-462.
-
(2011)
FASEB J
, vol.25
, pp. 449-462
-
-
Aranda, S.1
Laguna, A.2
de la Luna, S.3
-
6
-
-
0042330069
-
dDYRK2: a novel dual-specificity tyrosine-phosphorylation-regulated kinase in Drosophila
-
Lochhead PA, Sibbet G, Kinstrie R, Cleghon T, Rylatt M, et al. (2003) dDYRK2: a novel dual-specificity tyrosine-phosphorylation-regulated kinase in Drosophila. Biochem J 374: 381-391.
-
(2003)
Biochem J
, vol.374
, pp. 381-391
-
-
Lochhead, P.A.1
Sibbet, G.2
Kinstrie, R.3
Cleghon, T.4
Rylatt, M.5
-
7
-
-
0028839101
-
minibrain: a new protein kinase family involved in postembryonic neurogenesis in Drosophila
-
Tejedor F, Zhu XR, Kaltenbach E, Ackermann A, Baumann A, et al. (1995) minibrain: a new protein kinase family involved in postembryonic neurogenesis in Drosophila. Neuron 14: 287-301.
-
(1995)
Neuron
, vol.14
, pp. 287-301
-
-
Tejedor, F.1
Zhu, X.R.2
Kaltenbach, E.3
Ackermann, A.4
Baumann, A.5
-
8
-
-
0036724569
-
Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice
-
Fotaki V, Dierssen M, Alcantara S, Martinez S, Marti E, et al. (2002) Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice. Mol Cell Biol 22: 6636-6647.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 6636-6647
-
-
Fotaki, V.1
Dierssen, M.2
Alcantara, S.3
Martinez, S.4
Marti, E.5
-
9
-
-
57049159874
-
The protein kinase DYRK1A regulates caspase-9-mediated apoptosis during retina development
-
Laguna A, Aranda S, Barallobre MJ, Barhoum R, Fernandez E, et al. (2008) The protein kinase DYRK1A regulates caspase-9-mediated apoptosis during retina development. Dev Cell 15: 841-853.
-
(2008)
Dev Cell
, vol.15
, pp. 841-853
-
-
Laguna, A.1
Aranda, S.2
Barallobre, M.J.3
Barhoum, R.4
Fernandez, E.5
-
10
-
-
43049162678
-
Truncation of the Down syndrome candidate gene DYRK1A in two unrelated patients with microcephaly
-
Moller RS, Kubart S, Hoeltzenbein M, Heye B, Vogel I, et al. (2008) Truncation of the Down syndrome candidate gene DYRK1A in two unrelated patients with microcephaly. Am J Hum Genet 82: 1165-1170.
-
(2008)
Am J Hum Genet
, vol.82
, pp. 1165-1170
-
-
Moller, R.S.1
Kubart, S.2
Hoeltzenbein, M.3
Heye, B.4
Vogel, I.5
-
11
-
-
79551646485
-
Intragenic deletion in DYRK1A leads to mental retardation and primary microcephaly
-
van Bon BWM, Hoischen A, Hehir-Kwa J, de Brouwer APM, Ruivenkamp C, et al. (2011) Intragenic deletion in DYRK1A leads to mental retardation and primary microcephaly. Clin Genet 79: 296-299.
-
(2011)
Clin Genet
, vol.79
, pp. 296-299
-
-
van Bon, B.W.M.1
Hoischen, A.2
Hehir-Kwa, J.3
de Brouwer, A.P.M.4
Ruivenkamp, C.5
-
12
-
-
79952126118
-
Distinctive Phenotypic Abnormalities Associated with Submicroscopic 21q22 Deletion Including DYRK1A
-
Oegema R, de Klein A, Verkerk AJ, Schot R, Dumee B, et al. (2010) Distinctive Phenotypic Abnormalities Associated with Submicroscopic 21q22 Deletion Including DYRK1A. Mol Syndromol 1: 113-120.
-
(2010)
Mol Syndromol
, vol.1
, pp. 113-120
-
-
Oegema, R.1
de Klein, A.2
Verkerk, A.J.3
Schot, R.4
Dumee, B.5
-
13
-
-
33845937335
-
Dyrk1A phosphorylates alpha-synuclein and enhances intracellular inclusion formation
-
Kim EJ, Sung JY, Lee HJ, Rhim H, Hasegawa M, et al. (2006) Dyrk1A phosphorylates alpha-synuclein and enhances intracellular inclusion formation. J Biol Chem 281: 33250-33257.
-
(2006)
J Biol Chem
, vol.281
, pp. 33250-33257
-
-
Kim, E.J.1
Sung, J.Y.2
Lee, H.J.3
Rhim, H.4
Hasegawa, M.5
-
14
-
-
33846533244
-
The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease
-
Kimura R, Kamino K, Yamamoto M, Nuripa A, Kida T, et al. (2007) The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease. Hum Mol Genet 16: 15-23.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 15-23
-
-
Kimura, R.1
Kamino, K.2
Yamamoto, M.3
Nuripa, A.4
Kida, T.5
-
15
-
-
78651062069
-
MNB/DYRK1A as a multiple regulator of neuronal development
-
Tejedor FJ, Hammerle B, (2011) MNB/DYRK1A as a multiple regulator of neuronal development. FEBS J 278: 223-235.
-
(2011)
FEBS J
, vol.278
, pp. 223-235
-
-
Tejedor, F.J.1
Hammerle, B.2
-
17
-
-
70350512022
-
Function and regulation of Dyrk1A: towards understanding Down syndrome
-
Park J, Song WJ, Chung KC, (2009) Function and regulation of Dyrk1A: towards understanding Down syndrome. Cell Mol Life Sci 66: 3235-3240.
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 3235-3240
-
-
Park, J.1
Song, W.J.2
Chung, K.C.3
-
18
-
-
0029960341
-
Effects of single P-element insertions on olfactory behavior in Drosophila melanogaster
-
Anholt RR, Lyman RF, Mackay TF, (1996) Effects of single P-element insertions on olfactory behavior in Drosophila melanogaster. Genetics 143: 293-301.
-
(1996)
Genetics
, vol.143
, pp. 293-301
-
-
Anholt, R.R.1
Lyman, R.F.2
Mackay, T.F.3
-
19
-
-
0032857480
-
An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster: the Adh region
-
Ashburner M, Misra S, Roote J, Lewis SE, Blazej R, et al. (1999) An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster: the Adh region. Genetics 153: 179-219.
-
(1999)
Genetics
, vol.153
, pp. 179-219
-
-
Ashburner, M.1
Misra, S.2
Roote, J.3
Lewis, S.E.4
Blazej, R.5
-
20
-
-
77954716355
-
A paired-end sequencing strategy to map the complex landscape of transcription initiation
-
Ni T, Corcoran DL, Rach EA, Song S, Spana EP, et al. (2010) A paired-end sequencing strategy to map the complex landscape of transcription initiation. Nature Methods 7: 521-527.
-
(2010)
Nature Methods
, vol.7
, pp. 521-527
-
-
Ni, T.1
Corcoran, D.L.2
Rach, E.A.3
Song, S.4
Spana, E.P.5
-
21
-
-
79851485916
-
Transcription initiation patterns indicate divergent strategies for gene regulation at the chromatin level
-
Rach EA, Winter DR, Benjamin AM, Corcoran DL, Ni T, et al. (2011) Transcription initiation patterns indicate divergent strategies for gene regulation at the chromatin level. PLoS genetics 7: e1001274.
-
(2011)
PLoS Genetics
, vol.7
-
-
Rach, E.A.1
Winter, D.R.2
Benjamin, A.M.3
Corcoran, D.L.4
Ni, T.5
-
22
-
-
0028084578
-
The organization of the chemosensory system in Drosophila melanogaster: a review
-
Stocker RF, (1994) The organization of the chemosensory system in Drosophila melanogaster: a review. Cell Tissue Res 275: 3-26.
-
(1994)
Cell Tissue Res
, vol.275
, pp. 3-26
-
-
Stocker, R.F.1
-
23
-
-
83655165387
-
Building an ommatidium one cell at a time
-
Kumar JP, (2012) Building an ommatidium one cell at a time. Dev Dyn 241: 136-149.
-
(2012)
Dev Dyn
, vol.241
, pp. 136-149
-
-
Kumar, J.P.1
-
24
-
-
84868207944
-
Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48
-
Riazuddin S, Belyantseva IA, Giese AP, Lee K, Indzhykulian AA, et al. (2012) Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48. Nature Genet 44: 1265-1271.
-
(2012)
Nature Genet
, vol.44
, pp. 1265-1271
-
-
Riazuddin, S.1
Belyantseva, I.A.2
Giese, A.P.3
Lee, K.4
Indzhykulian, A.A.5
-
25
-
-
0027160708
-
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
-
Brand AH, Perrimon N, (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118: 401-415.
-
(1993)
Development
, vol.118
, pp. 401-415
-
-
Brand, A.H.1
Perrimon, N.2
-
26
-
-
84876556121
-
FlyBase: improvements to the bibliography
-
Marygold SJ, Leyland PC, Seal RL, Goodman JL, Thurmond J, et al. (2013) FlyBase: improvements to the bibliography. Nucleic Acids Res 41: D751-757.
-
(2013)
Nucleic Acids Res
, vol.41
-
-
Marygold, S.J.1
Leyland, P.C.2
Seal, R.L.3
Goodman, J.L.4
Thurmond, J.5
-
27
-
-
33645238760
-
Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals
-
Isono K, Nemoto K, Li Y, Takada Y, Suzuki R, et al. (2006) Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals. Mol Cell Biol 26: 2758-2771.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2758-2771
-
-
Isono, K.1
Nemoto, K.2
Li, Y.3
Takada, Y.4
Suzuki, R.5
-
28
-
-
0037297691
-
Characterization of Caenorhabditis elegans homologs of the Down syndrome candidate gene DYRK1A
-
Raich WB, Moorman C, Lacefield CO, Lehrer J, Bartsch D, et al. (2003) Characterization of Caenorhabditis elegans homologs of the Down syndrome candidate gene DYRK1A. Genetics 163: 571-580.
-
(2003)
Genetics
, vol.163
, pp. 571-580
-
-
Raich, W.B.1
Moorman, C.2
Lacefield, C.O.3
Lehrer, J.4
Bartsch, D.5
-
29
-
-
0017110220
-
Development of the Drosophila retina, a neurocrystalline lattice
-
Ready DF, Hanson TE, Benzer S, (1976) Development of the Drosophila retina, a neurocrystalline lattice. Dev Biol 53: 217-240.
-
(1976)
Dev Biol
, vol.53
, pp. 217-240
-
-
Ready, D.F.1
Hanson, T.E.2
Benzer, S.3
-
30
-
-
0024377179
-
The emergence of order in the Drosophila pupal retina
-
Cagan RL, Ready DF, (1989) The emergence of order in the Drosophila pupal retina. Dev Biol 136: 346-362.
-
(1989)
Dev Biol
, vol.136
, pp. 346-362
-
-
Cagan, R.L.1
Ready, D.F.2
-
31
-
-
0030584086
-
Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye
-
Freeman M, (1996) Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye. Cell 87: 651-660.
-
(1996)
Cell
, vol.87
, pp. 651-660
-
-
Freeman, M.1
-
32
-
-
0028352925
-
Neural specificity of elav expression: defining a Drosophila promoter for directing expression to the nervous system
-
Yao KM, White K, (1994) Neural specificity of elav expression: defining a Drosophila promoter for directing expression to the nervous system. J Neurochem 63: 41-51.
-
(1994)
J Neurochem
, vol.63
, pp. 41-51
-
-
Yao, K.M.1
White, K.2
-
33
-
-
77957348303
-
Separable transcriptional regulatory domains within Otd control photoreceptor terminal differentiation events
-
McDonald EC, Xie B, Workman M, Charlton-Perkins M, Terrell DA, et al. (2010) Separable transcriptional regulatory domains within Otd control photoreceptor terminal differentiation events. Dev Biol 347: 122-132.
-
(2010)
Dev Biol
, vol.347
, pp. 122-132
-
-
McDonald, E.C.1
Xie, B.2
Workman, M.3
Charlton-Perkins, M.4
Terrell, D.A.5
-
34
-
-
0036063617
-
Mnb/Dyrk1A is transiently expressed and asymmetrically segregated in neural progenitor cells at the transition to neurogenic divisions
-
Hammerle B, Vera-Samper E, Speicher S, Arencibia R, Martinez S, et al. (2002) Mnb/Dyrk1A is transiently expressed and asymmetrically segregated in neural progenitor cells at the transition to neurogenic divisions. Dev Biol 246: 259-273.
-
(2002)
Dev Biol
, vol.246
, pp. 259-273
-
-
Hammerle, B.1
Vera-Samper, E.2
Speicher, S.3
Arencibia, R.4
Martinez, S.5
-
35
-
-
79957648087
-
Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling
-
Hammerle B, Ulin E, Guimera J, Becker W, Guillemot F, et al. (2011) Transient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling. Development 138: 2543-2554.
-
(2011)
Development
, vol.138
, pp. 2543-2554
-
-
Hammerle, B.1
Ulin, E.2
Guimera, J.3
Becker, W.4
Guillemot, F.5
-
36
-
-
33746457418
-
Mirk/Dyrk1B: a multifunctional dual-specificity kinase involved in growth arrest, differentiation, and cell survival
-
Mercer SE, Friedman E, (2006) Mirk/Dyrk1B: a multifunctional dual-specificity kinase involved in growth arrest, differentiation, and cell survival. Cell Biochem Biophys 45: 303-315.
-
(2006)
Cell Biochem Biophys
, vol.45
, pp. 303-315
-
-
Mercer, S.E.1
Friedman, E.2
-
37
-
-
0001019046
-
YakA, a protein kinase required for the transition from growth to development in Dictyostelium
-
Souza GM, Lu S, Kuspa A, (1998) YakA, a protein kinase required for the transition from growth to development in Dictyostelium. Development 125: 2291-2302.
-
(1998)
Development
, vol.125
, pp. 2291-2302
-
-
Souza, G.M.1
Lu, S.2
Kuspa, A.3
-
38
-
-
84866754278
-
Emerging role of DYRK family protein kinases as regulators of protein stability in cell cycle control
-
Becker W, (2012) Emerging role of DYRK family protein kinases as regulators of protein stability in cell cycle control. Cell Cycle 11: 3389-3394.
-
(2012)
Cell Cycle
, vol.11
, pp. 3389-3394
-
-
Becker, W.1
-
39
-
-
0034651987
-
The Drosophila caspase DRONC is regulated by DIAP1
-
Meier P, Silke J, Leevers SJ, Evan GI, (2000) The Drosophila caspase DRONC is regulated by DIAP1. EMBO J 19: 598-611.
-
(2000)
EMBO J
, vol.19
, pp. 598-611
-
-
Meier, P.1
Silke, J.2
Leevers, S.J.3
Evan, G.I.4
-
40
-
-
0030840137
-
Defective learning in mutants of the Drosophila gene for a regulatory subunit of cAMP-dependent protein kinase
-
Goodwin SF, Del Vecchio M, Velinzon K, Hogel C, Russell SR, et al. (1997) Defective learning in mutants of the Drosophila gene for a regulatory subunit of cAMP-dependent protein kinase. J Neurochem 17: 8817-8827.
-
(1997)
J Neurochem
, vol.17
, pp. 8817-8827
-
-
Goodwin, S.F.1
Del Vecchio, M.2
Velinzon, K.3
Hogel, C.4
Russell, S.R.5
-
41
-
-
0024653991
-
Isolation and characterization of an olfactory mutant in Drosophila with a chemically specific defect
-
Helfand SL, Carlson JR, (1989) Isolation and characterization of an olfactory mutant in Drosophila with a chemically specific defect. Proc Natl Acad Sci U S A 86: 2908-2912.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 2908-2912
-
-
Helfand, S.L.1
Carlson, J.R.2
-
42
-
-
84857200001
-
Genetic variation in odorant receptors contributes to variation in olfactory behavior in a natural population of Drosophila melanogaster
-
Richgels PK, Rollmann SM, (2012) Genetic variation in odorant receptors contributes to variation in olfactory behavior in a natural population of Drosophila melanogaster. Chem Senses 37: 229-240.
-
(2012)
Chem Senses
, vol.37
, pp. 229-240
-
-
Richgels, P.K.1
Rollmann, S.M.2
-
43
-
-
33748897865
-
Quantitative trait loci for locomotor behavior in Drosophila melanogaster
-
Jordan KW, Morgan TJ, Mackay TF, (2006) Quantitative trait loci for locomotor behavior in Drosophila melanogaster. Genetics 174: 271-284.
-
(2006)
Genetics
, vol.174
, pp. 271-284
-
-
Jordan, K.W.1
Morgan, T.J.2
Mackay, T.F.3
-
44
-
-
79955506997
-
Prospero and Pax2 combinatorially control neural cell fate decisions by modulating Ras- and Notch-dependent signaling
-
Charlton-Perkins M, Whitaker SL, Fei Y, Xie B, Li-Kroeger D, et al. (2011) Prospero and Pax2 combinatorially control neural cell fate decisions by modulating Ras- and Notch-dependent signaling. Neural Dev 6: 20.
-
(2011)
Neural Dev
, vol.6
, pp. 20
-
-
Charlton-Perkins, M.1
Whitaker, S.L.2
Fei, Y.3
Xie, B.4
Li-Kroeger, D.5
|