Epidermal pigmentation in the human lineage is an adaptation to ultraviolet radiation

Journal of Human Evolution

Volumn 65, Issue 5, 2013, Pages 671-675

  Jablonski, Nina G ^a,b   Chaplin, George ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b Stellenbosch Institute of Advanced Study   (South Africa)

Author keywords

25(OH)D; 5 MTFH; 7 DHC; ASIP; Barrier function; DHFR; Eumelanin; Folate; MC1R; Melanin; MITF; NTDs; ROS; SC; SLC24A5; TEWL; UVA; UVB; UVR; Vitamin D

Indexed keywords

ADAPTATION; MELANIN; PIGMENT; ULTRAVIOLET RADIATION; VITAMIN;

AGOUTI PROTEIN; DIHYDROFOLATE REDUCTASE; EUMELANIN; FOLIC ACID; MELANIN; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; REACTIVE OXYGEN METABOLITE; VITAMIN D;

25(OH)D; 25-HYDROXYCHOLECALCIFEROL, OR 25-HYDROXYVITAMIN D, OR SERUM VITAMIN D; 5-METHYLTETRAHYDROFOLATE; 5-MTFH; 7-DEHYDROCHOLESTEROL; 7-DHC; ADAPTATION; ARTICLE; ASIP; BARRIER FUNCTION; DHFR; HUMAN; MC1R; MELANOCORTIN 1 RECEPTOR LOCUS; NEURAL TUBE DEFECT; NTDS; PHYSIOLOGY; RADIATION EXPOSURE; ROS; SC; SKIN PIGMENTATION; SKIN WATER LOSS; SLC24A5; SOLUTE CARRIER FAMILY 24 (SODIUM/POTASSIUM/CALCIUM EXCHANGER), MEMBER 5, SLC24A5; STRATUM CORNEUM; TEWL; ULTRAVIOLET A RADIATION; ULTRAVIOLET B RADIATION; ULTRAVIOLET RADIATION; UVA; UVB; UVR;

25(OH)D; 25-HYDROXYCHOLECALCIFEROL, OR 25-HYDROXYVITAMIN D, OR SERUM VITAMIN D; 5-METHYLTETRAHYDROFOLATE; 5-MTFH; 7-DEHYDROCHOLESTEROL; 7-DHC; AGOUTI SIGNALING PROTEIN; ASIP; BARRIER FUNCTION; DHFR; DIHYDROFOLATE REDUCTASE; EUMELANIN; FOLATE; MC1R; MELANIN; MELANOCORTIN 1 RECEPTOR LOCUS; MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR; MITF; NEURAL TUBE DEFECTS; NTDS; REACTIVE OXYGEN SPECIES; ROS; SC; SLC24A5; SOLUTE CARRIER FAMILY 24 (SODIUM/POTASSIUM/CALCIUM EXCHANGER), MEMBER 5, SLC24A5; STRATUM CORNEUM; TEWL; TRANSEPIDERMAL WATER LOSS; ULTRAVIOLET A RADIATION; ULTRAVIOLET B RADIATION; ULTRAVIOLET RADIATION; UVA; UVB; UVR; VITAMIN D;

ADAPTATION, BIOLOGICAL; HUMANS; MELANINS; SKIN PIGMENTATION; ULTRAVIOLET RAYS;

EID: 84885382175     PISSN: 00472484     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhevol.2013.06.004     Document Type: Article

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