Diagnostic Performance of Fractional Excretion of Urea and Fractional Excretion of Sodium in the Evaluations of Patients With Acute Kidney Injury With or Without Diuretic Treatment

American Journal of Kidney Diseases

Volumn 50, Issue 4, 2007, Pages 566-573

  Pépin, Marie Noëlle ^a   Bouchard, Josée ^a   Legault, Louis ^a   Éthier, Jean ^a  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

acute kidney injury; diagnostic accuracy; diuretics; fractional excretion of sodium; Fractional excretion of urea; sensitivity; specificity

Indexed keywords

DIURETIC AGENT; SODIUM; UREA;

ACUTE KIDNEY FAILURE; ADULT; AGED; ARTICLE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIAGNOSTIC ACCURACY; FEMALE; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; SENSITIVITY AND SPECIFICITY; SODIUM URINE LEVEL;

EID: 34548858177     PISSN: 02726386     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.ajkd.2007.07.001     Document Type: Article

References (24)

1. Uchino S., Bellomo R., Goldsmith D., et al. An assessment of the RIFLE criteria for acute renal failure in hospitalized patients. Crit Care Med 34 (2006) 1913-1917
2. Naveen S., Shubhada N.A., and Murray L.L. Acute renal failure. JAMA 289 (2003) 747-751
3. Chertow G.M., Burdick E., Honour M., et al. Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol 16 (2005) 3365-3370
4. Bellomo R., Kellum J.A., and Ronco C. Defining and classifying acute renal failure: From advocacy to consensus and validation of the RIFLE criteria. Intensive Care Med 33 (2007) 409-413
5. Liano F., and Pascual J. Epidemiology of acute renal failure: A prospective, multicenter, community-based study. Madrid Acute Renal Failure Study Group. Kidney Int 50 (1996) 811-818
6. Miller T.R., Anderson R.J., Linas S.L., et al. Urinary indices in acute renal failure: A prospective study. Ann Intern Med 89 (1978) 47-50
7. Espinel C.H., and Gregory A.W. Differential diagnosis of acute renal failure. Clin Nephrol 13 (1980) 73-77
8. Brosius F.C., and Lau K. Low fractional excretion of sodium in acute renal failure: Role of timing of the test and ischemia. Am J Nephrol 6 (1986) 450-457
9. Kamel S.K., Ethier J., Richardson R., Bear R.A., and Halperin M.L. Urine electrolytes and osmolality: When and how to use them. Am J Nephrol 10 (1990) 89-102
10. Choukroun G., Schmitt F., Martinez F., Drüeke T.B., and Bankir L. Low urine flow reduces the capacity to excrete a sodium load in humans. Am J Physiol 273 (1997) 1726-1733
11. Westhuyzen J., Endre Z.H., Reece G., Reith D.M., Saltissi D., and Morgan T.J. Measurement of tubular enzymuria facilitates early detection of acute renal impairment in the intensive care unit. Nephrol Dial Transplant 18 (2003) 543-551
12. Anderson R.J., and Schrier R.W. Acute renal failure. In: Schrier R.W., and Gottschalk C.W. (Eds). Diseases of the Kidney. ed 6 (1997), Little, Brown, Boston, MA 1069-1113
13. Steiner R.W. Interpreting the fractional excretion of sodium. Am J Med 77 (1984) 699-702
14. Diamond J.R., and Yoburn D. Non oliguric renal failure associated with a low fractional excretion of sodium. Ann Intern Med 96 (1982) 597-600
15. Kaplan A.A., and Kohn O.F. Fractional excretion of urea as a guide to renal dysfunction. Am J Nephrol 12 (1992) 49-54
16. Carvounis C.P., Nisar S., and Guro-Razuman S. Significance of the fractional excretion of urea in the differential diagnosis of acute renal failure. Kidney Int 62 (2002) 2223-2229
17. Bellomo R., Ronco C., Kellum J.A., et al. Acute renal failure-Definition, outcome measures, animal models, fluid therapy and information technology needs: The Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 8 (2004) R204-R212
18. Kellum J.A., Levin N., Bouman C., and Lameire N. Developing a consensus classification system for acute renal failure. Curr Opin Crit Care 8 (2002) 509-514
19. Dal Canton A., Fuiano G., Conte G., et al. Mechanism of increased plasma urea after diuretic therapy in uraemic patients. Clin Sci 68 (1985) 255-261
20. Conte G., Dal Canton A., Terribile M., et al. Renal handling of urea in subjects with persistent azotemia and normal renal function. Kidney Int 32 (1987) 721-727
21. Dole V.P. Back diffusion of urea in the mammalian kidney. Am J Physiol 139 (1943) 504-519
22. Fang L.S.T., Sirota R.A., Ebert T.H., and Lichtenstein N.S. Low fractional excretion of sodium with contrast media-induced acute renal failure. Arch Intern Med 140 (1980) 531-533
23. Corwin L., Schreiber M.J., and Fang L.S.T. Low fractional excretion of sodium: Occurrence with hemoglobinuric- and myoglobinuric-induced acute renal failure. Arch Intern Med 144 (1984) 981-982
24. Steiner R.W. Low fractional excretion of sodium in myoglobinuric renal failure. Arch Intern Med 142 (1982) 1216-1217