Phenotypic and genotypic characterization of induced acyclovir-resistant clinical isolates of herpes simplex virus type 1

Antiviral Research

Volumn 100, Issue 2, 2013, Pages 306-313

  Hussin, Ainulkhir ^a,b   Md Nor, Norefrina Shafinaz ^a   Ibrahim, Nazlina ^a  

^a UNIVERSITI KEBANGSAAN MALAYSIA   (Malaysia)

^b Hospital Lahad Datu   (Malaysia)

Author keywords

Acyclovir; DNA polymerase; Frameshift; Herpes simplex virus type 1; HSV 1; Thymidine kinase

Indexed keywords

ACICLOVIR; DNA POLYMERASE; THYMIDINE KINASE; VIRUS DNA; ANTIVIRUS AGENT; VIRUS PROTEIN;

AMINO ACID SUBSTITUTION; ANTIVIRAL RESISTANCE; ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; DNA POLYMORPHISM; DNA SEQUENCE; DOSE RESPONSE; FRAMESHIFT MUTATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC STABILITY; GENOTYPE; GENOTYPING TECHNIQUE; HERPES SIMPLEX VIRUS 1; HYDROGEN BOND; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STOP CODON; STRUCTURAL GENE; VIRUS ISOLATION; DRUG EFFECT; FRAMESHIFT; GENETIC SELECTION; GENETICS; HERPES SIMPLEX; HSV-1; HUMAN; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; MUTATION; VIROLOGY; VIRUS CULTURE;

HUMAN HERPESVIRUS 1;

ACYCLOVIR; DNA POLYMERASE; FRAMESHIFT; HERPES SIMPLEX VIRUS TYPE 1; HSV-1; THYMIDINE KINASE;

ACYCLOVIR; ANTIVIRAL AGENTS; DNA MUTATIONAL ANALYSIS; DRUG RESISTANCE, VIRAL; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HUMANS; MICROBIAL SENSITIVITY TESTS; MUTATION; SELECTION, GENETIC; SERIAL PASSAGE; VIRAL PROTEINS; VIRUS CULTIVATION;

EID: 84885358684     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2013.09.008     Document Type: Article

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