FOXO/TXNIP pathway is involved in the suppression of hepatocellular carcinoma growth by glutamate antagonist MK-801

BMC Cancer

Volumn 13, Issue , 2013, Pages

  Yamaguchi, Fuminori ^a   Hirata, Yuko ^a   Akram, Hossain ^a   Kamitori, Kazuyo ^a   Dong, Youyi ^a   Sui, Li ^a   Tokuda, Masaaki ^a  

^a KAGAWA UNIVERSITY   (Japan)

Author keywords

FOXO; G1 cell cycle arrest; HepG2; HLF; HuH 7; MK 801; NBQX; p27; TXNIP

Indexed keywords

6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; CYCLIN D1; DIZOCILPINE; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; PROTEIN P27; THIOREDOXIN INTERACTING PROTEIN; TRANSCRIPTION FACTOR FKHR;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CELL VIABILITY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; FOXO GENE; G1 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE SILENCING; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LIVER CELL CARCINOMA; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; TXNIP GENE; UPREGULATION; WESTERN BLOTTING;

CARCINOMA, HEPATOCELLULAR; CARRIER PROTEINS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; RECEPTORS, N-METHYL-D-ASPARTATE; SIGNAL TRANSDUCTION;

EID: 84885357917     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-13-468     Document Type: Article

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