Activation of P27kip1-cyclin D1/E-CDK2 pathway by polysaccharide from Phellinus linteus leads to S-phase arrest in HT-29 cells

Chemico-Biological Interactions

Volumn 206, Issue 2, 2013, Pages 222-229

  Zhong, Shi ^a   Ji, Dong Feng ^a   Li, You Gui ^a   Lin, Tian Bao ^a   Lv, Zhi Qiang ^a   Chen, Hua Ping ^b  

^a INSTITUTE OF PLANT PROTECTION AND MICROBIOLOGY   (China)

^b Hangzhou Qing Zheng Biological Science Technologies Co   (China)

Author keywords

Cyclins CDK complexes; P27kip1; Polysaccharide; S phase arrest

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CISPLATIN; CYCLIN D; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN E; LIPID PEROXIDE; PHELLINUS LINTEUS POLYSACCHARIDE; POLYSACCHARIDE; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; AUTOPHAGY; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION; COLORECTAL CARCINOMA; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; IN VIVO STUDY; LIVER LEVEL; MOUSE; NONHUMAN; PHELLINUS LINTEUS; PROTEIN EXPRESSION; S PHASE CELL CYCLE CHECKPOINT; TUMOR VOLUME; WEIGHT GAIN;

CYCLINS/CDK COMPLEXES; P27KIP1; POLYSACCHARIDE; S-PHASE ARREST;

ANIMALS; CACO-2 CELLS; CELL LINE; CELL PROLIFERATION; CYCLIN D1; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE INHIBITOR P27; FUNGI; HT29 CELLS; HUMANS; MICE; POLYSACCHARIDES; S PHASE CELL CYCLE CHECKPOINTS; SIGNAL TRANSDUCTION;

INONOTUS LINTEUS; MAMMALIA; MUS;

EID: 84885356072     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2013.09.008     Document Type: Article

References (30)

1. X. Li, L.L. Jiao, X. Zhang, W.M. Tian, S. Chen, and L.P. Zhang Anti-tumor and immunomodulating activities of proteoglycans from mycelium of Phellinus nigricans and culture medium Int. Immunopharmacol. 8 2008 909 915
2. G. Li, D.H. Kim, T.D. Kim, B.J. Park, H.D. Park, J.I. Park, M.K. Na, H.C. Kim, N.D. Hong, K. Lim, B.D. Hwang, and W.H. Yoon Protein-bound polysaccharide from Phellinus linteus induces G2/M phase arrest and apoptosis in SW480 human colon cancer cells Cancer Lett. 216 2004 175 181 (Pubitemid 39463321)
3. H.M. Kim, S.B. Han, G.T. Oh, Y.H. Kim, D.H. Hong, N.D. Hong, and I.D. Yoo Stimulation of humoral and cell mediated immunity by polysaccharide from mushroom Phellinus linteus Int. J. Immunopharmacol. 18 1996 295 303 (Pubitemid 26361773)
4. G.Y. Kim, Y.H. Oh, and Y.M. Park Acidic polysaccharide isolated from Phellinus linteus induces nitric oxide-mediated tumoricidal activity of macrophages through protein tyrosine kinase and protein kinase C Biochem. Biophys. Res. Commun. 309 2003 399 407
5. S.B. Han, C.W. Lee, Y.J. Jeon, N.D. Hong, I.D. Yoo, K.H. Yang, and H.M. Kim The inhibitory effect of polysaccharide isolated from Phellinus linteus on tumor growth and metastasis Immunopharmacology 41 1999 157 164 (Pubitemid 29099828)
6. Y.G. Li, D.F. Ji, S. Zhong, J.X. Zhu, S. Chen, and G.Y. Hu Anti-tumor effects of proteoglycan from Phellinus Linteus by immunomodulating and inhibiting Reg IV/EGFR/Akt signaling pathway in colorectal carcinoma Int. J. Biol. Macromol. 48 2011 511 517
7. L. Gamet-Payrastre, P. Li, S. Lumeau, G. Cassar, M.A. Dupont, S. Chevolleau, N. Gasc, J. Tulliez, and F. Terce Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells Cancer Res. 60 2000 1426 1433 (Pubitemid 30152017)
8. A.W. Murray Recycling the cell cycle: cyclins revisited Cell 116 2004 221 234 (Pubitemid 38167314)
9. F.U. OuYang, G.B. Wang, W. Guo, Y.Y. Zhang, W.H. Xiang, and M. Zhao AKT signalling and mitochondrial pathways are involved in mushroom polysaccharide-induced apoptosis and G1 or S phase arrest in human hepatoma cells Food Chem. 138 2013 2130 2139
10. C.X. Zhang, and K.X. Huang Mechanism of apoptosis induced by a polysaccharide, from the loach Misgurnus anguillicaudatus (MAP) in human hepatocellular carcinoma cells Toxicol. Appl. Pharm. 210 2006 236 245
11. X.Q. Wang, Y.G. Li, S. Zhong, H. Zhang, X.Y. Wang, P.P. Qi, and H. Xu Oxidative injury is involved in fipronil-induced G2/M phase arrest and apoptosis in Spodoptera frugiperda (Sf9) cell line Pestic. Biochem. Phys. 105 2013 122 130
12. Y.G. Li, D.F. Ji, S. Zhong, T.B. Lin, Z.Q. Lv, G.Y. Hu, and X. Wang 1-Deoxynojirimycin inhibits glucose absorption and accelerates glucose metabolism in streptozotocin-induced diabetic mice Sci. Rep. 3 2013 1377 10.1038/srep01377
13. B. Ory, F. Blanchard, S. Battaglia, F. Gouin, F. Redini, and D. Heymann Zoledronic acid activates the DNA S-phase checkpoint and induces osteosarcoma cell death characterized by apoptosis-inducing factor and endonuclease-G translocation independently of p53 and retinoblastomastatus Mol. Pharmacol. 71 2007 333 343 (Pubitemid 46021003)
14. Y.C. Li, Q.Y. Luo, L. Yuan, C.X. Miao, X.S. Mu, W. Xiao, J.C. Li, T.M. Sun, and E.L. Ma JNK-dependent Atg4 upregulation mediates asperphenamate derivative BBP-induced autophagy in MCF-7 cells Toxicol. Appl. Pharm. 263 2012 21 31
15. T. Kanzawa, Y. Kondo, H. Ito, S. Kondo, and I. Germano Induction of autophagic cell death in malignant glioma cells by arsenic trioxide Cancer Res. 63 2003 2103 2108 (Pubitemid 36538613)
16. Y. Shao, Z. Gao, P.A. Marks, and X. Jiang Apoptotic and autophagic cell death induced by histone deacetylase inhibitors Proc. Natl. Acad. Sci. USA 101 2004 18030 18035 (Pubitemid 40054069)
17. S.J. Lee, Y.H. Cho, K. Park, E.J. Kim, K.H. Jung, S.S. Park, W.J. Kim, and S.K. Moon Magnolol elicits activation of the extracellular signal-regulated kinase pathway by inducing p27KIP1- mediated G2/M-phase cell cycle arrest in human urinary bladder cancer 5637 cells Biochem. Pharmacol. 75 2008 2289 2300
18. C.J. Sherr Cancer cell cycles Science 274 1996 1672 1677
19. C.J. Sherr G1 phase progression: cycling on cue Cell 79 1994 551 555 (Pubitemid 24363798)
20. N. Takai, T. Ueda, K. Nasu, S. Yamashita, M. Toyofuku, and H. Narahara Targeting calcium/calmodulin-dependence kinase I and II as a potential anti-proliferation remedy for endometrial carcinomas Cancer Lett. 277 2009 235 243
21. M. Zhang, A.G. Wang, T. Xia, and P. He Effects of fluoride on DNA damage, S-phase cell-cycle arrest and the expression of NF-κB in primary cultured rat hippocampal neurons Toxicol. Lett. 179 2008 1 5
22. T.A. Ajith, and K.K. Janardhanan Cytotoxic and antitumor activities of a polypore macrofungus, Phellinus rimosus (Berk) Pilat J. Ethnopharmacol. 84 2003 157 162 (Pubitemid 36324253)
23. G.F. Draetta Cell cycle: Will the real Cdk-activating kinase please stand up Curr. Biol. 7 1997 50 52
24. J. Moon, S.J. Yu, H.S. Kim, and J. Sohn Induction of G1 cell cycle arrest and p27KIP1 increase by panaxydol Isolated from Panax ginseng Biochem. Pharmacol. 59 2000 1109 1116 (Pubitemid 30110503)
25. J.M. Adams, and S. Cory The Bcl-2 apoptotic switch in cancer development and therapy Oncogene 26 2007 1324 1337 (Pubitemid 46328466)
26. J. Vlach, S. Hennecke, and B. Amati Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27 EMBO J. 16 1997 5334 5344 (Pubitemid 27380141)
27. K. Polyak, M.H. Lee, H. Erdjument-Bromage, A. Koff, J.M. Roberts, P. Tempst, and J. Massague Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals Cell 78 1994 59 66
28. S. Coats, W.M. Flanagan, J. Nourse, and J.M. Roberts Requirement of p27KIP1 for restriction point control of the fibroblast cell cycle Science 272 1996 877 880
29. J. Nourse, E. Firpo, W.M. Flanagan, S. Coats, K. Polyak, M.H. Lee, J. Massague, G.R. Crabtree, and J.M. Roberts Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin Nature 72 1994 570 573
30. L. Hengst, and S.I. Reed Translational control of p27Kip1 accumulation during the cell cycle Science 271 1996 1861 1864