메뉴 건너뛰기




Volumn 309, Issue 2, 2003, Pages 399-407

Acidic polysaccharide isolated from Phellinus linteus induces nitric oxide-mediated tumoricidal activity of macrophages through protein tyrosine kinase and protein kinase C

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CD18 ANTIGEN; GENISTEIN; IMMUNOMODULATING AGENT; NITRIC OXIDE; POLYSACCHARIDE; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; STAUROSPORINE;

EID: 0042925519     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2003.08.018     Document Type: Article
Times cited : (77)

References (48)
  • 1
    • 0037411776 scopus 로고    scopus 로고
    • Purification and characterization of acidic proteo-heteroglycan from the fruiting body of Phellinus linteus (Berk. & M. A. Curtis) Teng
    • Kim G.Y., Park H.S., Nam B.H., Lee S.J., Lee J.D. Purification and characterization of acidic proteo-heteroglycan from the fruiting body of Phellinus linteus (Berk. & M. A. Curtis) Teng. Biores. Technol. 87:2003;81-87.
    • (2003) Biores. Technol. , vol.87 , pp. 81-87
    • Kim, G.Y.1    Park, H.S.2    Nam, B.H.3    Lee, S.J.4    Lee, J.D.5
  • 2
    • 0032984321 scopus 로고    scopus 로고
    • The inhibitory effect of polysaccharides isolated from Phellinus linteus on tumor growth and metastasis
    • Han S.B., Lee C.W., Jeon Y.J., Hong N.D., Yoo I.D., Yang K.H., Kim H.M. The inhibitory effect of polysaccharides isolated from Phellinus linteus on tumor growth and metastasis. Immunopharmacology. 41:1999;157-164.
    • (1999) Immunopharmacology , vol.41 , pp. 157-164
    • Han, S.B.1    Lee, C.W.2    Jeon, Y.J.3    Hong, N.D.4    Yoo, I.D.5    Yang, K.H.6    Kim, H.M.7
  • 3
    • 0030152039 scopus 로고    scopus 로고
    • Stimulation of humoral and cell mediated immunity by polysaccharide from mushroom Phellinus linteus
    • Kim H.M., Han S.B., Oh G.T., Kim Y.H., Hong D.H., Hong N.D., Yoo I.D. Stimulation of humoral and cell mediated immunity by polysaccharide from mushroom Phellinus linteus. Int. J. Immunopharmacol. 18:1996;295-303.
    • (1996) Int. J. Immunopharmacol. , vol.18 , pp. 295-303
    • Kim, H.M.1    Han, S.B.2    Oh, G.T.3    Kim, Y.H.4    Hong, D.H.5    Hong, N.D.6    Yoo, I.D.7
  • 4
    • 0019639364 scopus 로고
    • The role of cell-mediated immunity in bacterial infections
    • Hahn H., Kaufmann S.H.E. The role of cell-mediated immunity in bacterial infections. Rev. Infect. Dis. 3:1981;1221-1250.
    • (1981) Rev. Infect. Dis. , vol.3 , pp. 1221-1250
    • Hahn, H.1    Kaufmann, S.H.E.2
  • 5
    • 0026755218 scopus 로고
    • Tumoricidal activation of murine resident peritoneal macrophage by interleukin 2 and tumor necrosis factor
    • Verstovsek S., Maccubbin D., Mihich E. Tumoricidal activation of murine resident peritoneal macrophage by interleukin 2 and tumor necrosis factor. Cancer Res. 52:1992;3880-3885.
    • (1992) Cancer Res. , vol.52 , pp. 3880-3885
    • Verstovsek, S.1    Maccubbin, D.2    Mihich, E.3
  • 6
    • 0027292446 scopus 로고
    • Therapy of cancer metastasis by systemic activation of macrophages; From bench to the clinic
    • Fidler I.J., Kleinerman E.S. Therapy of cancer metastasis by systemic activation of macrophages; from bench to the clinic. Res. Immunol. 144:1993;274-276.
    • (1993) Res. Immunol. , vol.144 , pp. 274-276
    • Fidler, I.J.1    Kleinerman, E.S.2
  • 7
    • 0032944216 scopus 로고    scopus 로고
    • The polysaccharide portion of lipopolysaccharide regulates antigen-specific T-cell activation via effects on macrophage-mediated antigen processing
    • Zirk N.M., Hashmi S.F., Ziegler H.K. The polysaccharide portion of lipopolysaccharide regulates antigen-specific T-cell activation via effects on macrophage-mediated antigen processing. Infect. Immun. 67:1999;319-326.
    • (1999) Infect. Immun. , vol.67 , pp. 319-326
    • Zirk, N.M.1    Hashmi, S.F.2    Ziegler, H.K.3
  • 8
    • 0023576142 scopus 로고
    • Synthesis of nitrite and nitrate in macrophage cell lines
    • Stuehr D.J., Marletta M.A. Synthesis of nitrite and nitrate in macrophage cell lines. Cancer Res. 47:1987;5590-5594.
    • (1987) Cancer Res. , vol.47 , pp. 5590-5594
    • Stuehr, D.J.1    Marletta, M.A.2
  • 9
    • 0024434870 scopus 로고
    • Antitumoral effects of lipopolysaccharide, tumor necrosis factor, interferon and activated macrophages: Synergism and tissue distribution
    • Choriki M., Freudenberg M., Calanos C., Poindrom P., Bartholeyns J. Antitumoral effects of lipopolysaccharide, tumor necrosis factor, interferon and activated macrophages: synergism and tissue distribution. Anticancer Res. 9:1989;1185-1190.
    • (1989) Anticancer Res. , vol.9 , pp. 1185-1190
    • Choriki, M.1    Freudenberg, M.2    Calanos, C.3    Poindrom, P.4    Bartholeyns, J.5
  • 10
    • 0025304202 scopus 로고
    • Lymphokines and bacteria that induce tumoricidal activity, trigger a different secretary response in macrophages
    • Keller R., Keist R., Frei K. Lymphokines and bacteria that induce tumoricidal activity, trigger a different secretary response in macrophages. Eur. J. Immunol. 20:1990;690-698.
    • (1990) Eur. J. Immunol. , vol.20 , pp. 690-698
    • Keller, R.1    Keist, R.2    Frei, K.3
  • 11
    • 0028577432 scopus 로고
    • Enhancement of cytokine production by macrophages stimulated with (1→3 )-β-glucan, Grifolan (GRN), isolated from Grifola frondosa
    • Adachi Y., Okazaki M., Ohno N., Yadamae Y. Enhancement of cytokine production by macrophages stimulated with. (1→3 )-β-glucan, Grifolan (GRN), isolated from Grifola frondosa Biol. Pharm. Bull. 17:1994;1554-1560.
    • (1994) Biol. Pharm. Bull. , vol.17 , pp. 1554-1560
    • Adachi, Y.1    Okazaki, M.2    Ohno, N.3    Yadamae, Y.4
  • 12
    • 0025779160 scopus 로고
    • Tumor necrosis factor. New insights into the molecular mechanisms of its multiple actions
    • Vilcek J., Lee T.H. Tumor necrosis factor. New insights into the molecular mechanisms of its multiple actions. J. Biol. Chem. 266:1991;7313-7316.
    • (1991) J. Biol. Chem. , vol.266 , pp. 7313-7316
    • Vilcek, J.1    Lee, T.H.2
  • 14
    • 0023147156 scopus 로고
    • Secretory products of macrophages
    • Nathan C.F. Secretory products of macrophages. J. Clin. Invest. 79:1987;319-326.
    • (1987) J. Clin. Invest. , vol.79 , pp. 319-326
    • Nathan, C.F.1
  • 16
    • 0026670962 scopus 로고
    • Both tumor necrosis factor and nitric oxide participate in lysis of simian virus 40-transformed cells by activated macrophages
    • Duerksen-Hughes P.J., Day D., Laster S.M., Zachariades N.A., Aquino L., Gooding L.R. Both tumor necrosis factor and nitric oxide participate in lysis of simian virus 40-transformed cells by activated macrophages. J. Immunol. 149:1992;2114-2122.
    • (1992) J. Immunol. , vol.149 , pp. 2114-2122
    • Duerksen-Hughes, P.J.1    Day, D.2    Laster, S.M.3    Zachariades, N.A.4    Aquino, L.5    Gooding, L.R.6
  • 17
    • 0027459588 scopus 로고
    • Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide
    • Lorsbach R.B., Murphy W.J., Lowenstein C.J., Snyder S.H., Russell S.W. Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide. J. Biol. Chem. 268:1993;1908-1913.
    • (1993) J. Biol. Chem. , vol.268 , pp. 1908-1913
    • Lorsbach, R.B.1    Murphy, W.J.2    Lowenstein, C.J.3    Snyder, S.H.4    Russell, S.W.5
  • 18
    • 0024584020 scopus 로고
    • Nitric oxide: A macrophage product responsible for cytostasis and respiratory inhibition in tumor target cell
    • Stuehr D.J., Nathan C.F. Nitric oxide: a macrophage product responsible for cytostasis and respiratory inhibition in tumor target cell. J. Exp. Med. 169:1989;1543-1555.
    • (1989) J. Exp. Med. , vol.169 , pp. 1543-1555
    • Stuehr, D.J.1    Nathan, C.F.2
  • 20
    • 0029048442 scopus 로고
    • Peptidoglycan induces transcription and secretion of TNF-α and activation of Lyn, extracellular signal-regulated kinase, and Rsk signal transduction proteins in mouse macrophages
    • Gupta D., Jin Y., Dziarski R. Peptidoglycan induces transcription and secretion of TNF-α and activation of Lyn, extracellular signal-regulated kinase, and Rsk signal transduction proteins in mouse macrophages. J. Immunol. 155:1995;2620-2630.
    • (1995) J. Immunol. , vol.155 , pp. 2620-2630
    • Gupta, D.1    Jin, Y.2    Dziarski, R.3
  • 21
    • 0027537341 scopus 로고
    • Activation of tumoricidal properties in macrophages by lipopolysaccharide requires protein-tyrosine kinase activity
    • Dong Z., O'Brian C.A., Fidler I.J. Activation of tumoricidal properties in macrophages by lipopolysaccharide requires protein-tyrosine kinase activity. J. Leukocyte Biol. 53:1993;53-60.
    • (1993) J. Leukocyte Biol. , vol.53 , pp. 53-60
    • Dong, Z.1    O'Brian, C.A.2    Fidler, I.J.3
  • 22
    • 0042100544 scopus 로고
    • Involvement of protein kinase C and tyrosine kinase in tumoricidal activation of macrophage induced by Streptococcus pneumoniae type II capsular polysaccharide
    • Um S.H., Rhee D.K., Pyo S.K. Involvement of protein kinase C and tyrosine kinase in tumoricidal activation of macrophage induced by Streptococcus pneumoniae type II capsular polysaccharide. Int. Immunopharmacol. 5:1993;1119-1128.
    • (1993) Int. Immunopharmacol. , vol.5 , pp. 1119-1128
    • Um, S.H.1    Rhee, D.K.2    Pyo, S.K.3
  • 23
    • 0034113629 scopus 로고    scopus 로고
    • Innate and adaptive lymphoid cells in the human lever
    • Doherty D.G., O'Farrelly C. Innate and adaptive lymphoid cells in the human lever. Immunol. Rev. 174:2000;5-20.
    • (2000) Immunol. Rev. , vol.174 , pp. 5-20
    • Doherty, D.G.1    O'Farrelly, C.2
  • 24
    • 0027160034 scopus 로고
    • CR3 (CD11b, CD18): A phagocyte and NK cell membrane receptor with multiple ligand specificities and functions
    • Ross G.D., Větvička V. CR3 (CD11b, CD18): a phagocyte and NK cell membrane receptor with multiple ligand specificities and functions. Clin. Exp. Immunol. 92:1993;181-184.
    • (1993) Clin. Exp. Immunol. , vol.92 , pp. 181-184
    • Ross, G.D.1    Větvička, V.2
  • 25
    • 0025738889 scopus 로고
    • The function of human NK cells is enhanced by β-glucan, a ligand of CR3 (CD11b/CD18)
    • Renzo L.D., Yefenof E., Klein E. The function of human NK cells is enhanced by β-glucan, a ligand of CR3 (CD11b/CD18). Eur. J. Immunol. 21:1991;1755-1758.
    • (1991) Eur. J. Immunol. , vol.21 , pp. 1755-1758
    • Renzo, L.D.1    Yefenof, E.2    Klein, E.3
  • 26
    • 0030029478 scopus 로고    scopus 로고
    • Analysis of the sugar specificity and molecular location of the β-glucan-binding lectin site of complement receptor type 3 (CD11b/CD18)
    • Thornton B.P., Větvička V., Pitman M., Goldman R.C., Ross G.D. Analysis of the sugar specificity and molecular location of the β-glucan-binding lectin site of complement receptor type 3 (CD11b/CD18). J. Immunol. 156:1996;1235-1246.
    • (1996) J. Immunol. , vol.156 , pp. 1235-1246
    • Thornton, B.P.1    Větvička, V.2    Pitman, M.3    Goldman, R.C.4    Ross, G.D.5
  • 27
    • 0029148878 scopus 로고
    • Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: Downregulation by cytokines and bacterial products
    • Sallusto F., Cella M., Danieli C., Lanzavecchia A. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J. Exp. Med. 182:1995;389-400.
    • (1995) J. Exp. Med. , vol.182 , pp. 389-400
    • Sallusto, F.1    Cella, M.2    Danieli, C.3    Lanzavecchia, A.4
  • 28
    • 0030692855 scopus 로고    scopus 로고
    • Inhibition of mannose receptor-mediated clearance of tissue-type plasminogen activator (t-PA) by dextran: A new explanation for its antithrombotic effect
    • Noorman F., Barett-Bergshoeff M.M., Bekkers M., Emeis J.J., Rijken D.C. Inhibition of mannose receptor-mediated clearance of tissue-type plasminogen activator (t-PA) by dextran: a new explanation for its antithrombotic effect. Thromb. Haemastasis. 78:1997;1249-1254.
    • (1997) Thromb. Haemastasis , vol.78 , pp. 1249-1254
    • Noorman, F.1    Barett-Bergshoeff, M.M.2    Bekkers, M.3    Emeis, J.J.4    Rijken, D.C.5
  • 30
    • 0022530995 scopus 로고
    • Clinical evaluation of Shizophyllan combined with irradiation in patients with cervical cancer. A randomized controlled study
    • Okamura K., Suzuki M., Chihara T., Fujiwara A., Fukuda T., Goto S., Ichinohe K., Jimi S., Kasamatsu T., Kawai N.et al. Clinical evaluation of Shizophyllan combined with irradiation in patients with cervical cancer. A randomized controlled study. Cancer. 58:1986;865-872.
    • (1986) Cancer , vol.58 , pp. 865-872
    • Okamura, K.1    Suzuki, M.2    Chihara, T.3    Fujiwara, A.4    Fukuda, T.5    Goto, S.6    Ichinohe, K.7    Jimi, S.8    Kasamatsu, T.9    Kawai, N.10
  • 31
    • 0042594630 scopus 로고    scopus 로고
    • Proteoglycan isolated from Phellinus linteus activates murine B lymphocytes via protein kinase C and protein tyrosine kinase
    • Kim G.Y., Park S.K., Lee M.K., Lee S.H., Oh Y.H., Kwak J.Y., Yoon S., Lee J.D., Park Y.M. Proteoglycan isolated from Phellinus linteus activates murine B lymphocytes via protein kinase C and protein tyrosine kinase. Int. Immunopharmacol. 506:2003;1281-1292.
    • (2003) Int. Immunopharmacol. , vol.506 , pp. 1281-1292
    • Kim, G.Y.1    Park, S.K.2    Lee, M.K.3    Lee, S.H.4    Oh, Y.H.5    Kwak, J.Y.6    Yoon, S.7    Lee, J.D.8    Park, Y.M.9
  • 32
    • 0027935971 scopus 로고
    • CARE-LASS (calcein-release assay), an improved fluorescence-based test system to measure cytotoxic T lymphocyte activity
    • Lichtenfels R., Biddison W.E., Schulz H., Vogt A.B., Martin R. CARE-LASS (calcein-release assay), an improved fluorescence-based test system to measure cytotoxic T lymphocyte activity. J. Immunol. Methods. 172:1994;227-239.
    • (1994) J. Immunol. Methods , vol.172 , pp. 227-239
    • Lichtenfels, R.1    Biddison, W.E.2    Schulz, H.3    Vogt, A.B.4    Martin, R.5
  • 33
    • 0036319575 scopus 로고    scopus 로고
    • The roles of ERK1/2 and p38 MAP kinases in the preventive mechanisms of mushroom Phellinus linteus against the inhibition of gap junctional intercellular communication by hydrogen peroxide
    • Cho J.H., Cho S.D., Hu H., Kim S.H., Lee S.K., Lee Y.S., Kang K.S. The roles of ERK1/2 and p38 MAP kinases in the preventive mechanisms of mushroom Phellinus linteus against the inhibition of gap junctional intercellular communication by hydrogen peroxide. Carcinogenesis. 23:2002;1163-1169.
    • (2002) Carcinogenesis , vol.23 , pp. 1163-1169
    • Cho, J.H.1    Cho, S.D.2    Hu, H.3    Kim, S.H.4    Lee, S.K.5    Lee, Y.S.6    Kang, K.S.7
  • 34
    • 0023092102 scopus 로고
    • Macrophage cytotoxicity: Role for L-arginine deaminase and imino nitrogen oxidation to nitrite
    • Hibbs J.B. Jr., Taintor R.R., Vavrin Z. Macrophage cytotoxicity: role for L-arginine deaminase and imino nitrogen oxidation to nitrite. Science. 235:1987;473-476.
    • (1987) Science , vol.235 , pp. 473-476
    • Hibbs J.B., Jr.1    Taintor, R.R.2    Vavrin, Z.3
  • 36
    • 0027485903 scopus 로고
    • Macrophage nitric oxide synthesis delays progression of ultraviolet light-induced murine skin cancers
    • Yim C.Y., Bastian N.R., Smith J.C., Hibbs J.B. Jr., Samlowski W.E. Macrophage nitric oxide synthesis delays progression of ultraviolet light-induced murine skin cancers. Cancer Res. 53:1993;5507-5511.
    • (1993) Cancer Res. , vol.53 , pp. 5507-5511
    • Yim, C.Y.1    Bastian, N.R.2    Smith, J.C.3    Hibbs J.B., Jr.4    Samlowski, W.E.5
  • 38
    • 0028929559 scopus 로고
    • Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells
    • Xie K., Huang S., Dong Z., Juang S.H., Gutman M., Xie Q.W., Nathan C., Fidler I.J. Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells. J. Exp. Med. 181:1995;1333-1343.
    • (1995) J. Exp. Med. , vol.181 , pp. 1333-1343
    • Xie, K.1    Huang, S.2    Dong, Z.3    Juang, S.H.4    Gutman, M.5    Xie, Q.W.6    Nathan, C.7    Fidler, I.J.8
  • 39
    • 0032544330 scopus 로고    scopus 로고
    • Protein A induces no production: Involvement of tyrosine kinase, phospholipase c, and protein kinase C
    • Goenka S., Das T., Sa G., Ray P.K. Protein A induces no production: involvement of tyrosine kinase, phospholipase c, and protein kinase C. Biochem. Biophys. Res. Commun. 250:1998;425-429.
    • (1998) Biochem. Biophys. Res. Commun. , vol.250 , pp. 425-429
    • Goenka, S.1    Das, T.2    Sa, G.3    Ray, P.K.4
  • 40
    • 0026351096 scopus 로고
    • Basal activation of protein kinase C in rat alveolar macrophages: Implications for arachidonate metabolism
    • Peter-Golden M., McNish R.W., Sporn P.H., Balazovich K. Basal activation of protein kinase C in rat alveolar macrophages: implications for arachidonate metabolism. Am. J. Physiol. 261:1991;462-471.
    • (1991) Am. J. Physiol. , vol.261 , pp. 462-471
    • Peter-Golden, M.1    McNish, R.W.2    Sporn, P.H.3    Balazovich, K.4
  • 41
    • 0032052764 scopus 로고    scopus 로고
    • Protein kinase C: A potential pathway of macrophage activation with cisplatin
    • Shishodia S., Shrivastava A., Sodhi A. Protein kinase C: a potential pathway of macrophage activation with cisplatin. Immunol. Lett. 61:1998;179-186.
    • (1998) Immunol. Lett. , vol.61 , pp. 179-186
    • Shishodia, S.1    Shrivastava, A.2    Sodhi, A.3
  • 42
    • 0037189172 scopus 로고    scopus 로고
    • Activation of B lymphocytes by GLIS, a bioactive proteoglycan from Ganoderma lucidum
    • Zhang J., Tang Q., Zimmerman-Kordmann M., Reutter W., Fan H. Activation of B lymphocytes by GLIS, a bioactive proteoglycan from Ganoderma lucidum. Life Sci. 71:2002;623-638.
    • (2002) Life Sci. , vol.71 , pp. 623-638
    • Zhang, J.1    Tang, Q.2    Zimmerman-Kordmann, M.3    Reutter, W.4    Fan, H.5
  • 43
    • 0025910553 scopus 로고
    • Isolation and characterization of β-glucan receptors on human mononuclear phagocytes
    • Czop J.K., Kay J. Isolation and characterization of β-glucan receptors on human mononuclear phagocytes. J. Exp. Med. 173:1991;1511-1520.
    • (1991) J. Exp. Med. , vol.173 , pp. 1511-1520
    • Czop, J.K.1    Kay, J.2
  • 44
    • 0032555519 scopus 로고    scopus 로고
    • A novel carbohydrate-glycosphingolipid interaction between a β-(1-3)-glucan immunomodulator, PGG-glucan, and lactosylceramide of human leukocytes
    • Zimmerman J.W., Lindermuth J., Fish P.A., Palace G.P., Stevenson T.T., DeMong D.E. A novel carbohydrate-glycosphingolipid interaction between a β-(1-3)-glucan immunomodulator, PGG-glucan, and lactosylceramide of human leukocytes. J. Biol. Chem. 273:1999;22014-22020.
    • (1999) J. Biol. Chem. , vol.273 , pp. 22014-22020
    • Zimmerman, J.W.1    Lindermuth, J.2    Fish, P.A.3    Palace, G.P.4    Stevenson, T.T.5    DeMong, D.E.6
  • 45
    • 0345552244 scopus 로고    scopus 로고
    • The β-glucan-binding lectin site of mouse CR3 (CD11b/CD18) and its function in generating a primed state of the receptor that mediates cytotoxic activation in response to iC3b-opsonized target cells
    • Xia Y., Větvička V., Yan J., Hanikyrova M., Mayadas T.N., Ross G.D. The β-glucan-binding lectin site of mouse CR3 (CD11b/CD18) and its function in generating a primed state of the receptor that mediates cytotoxic activation in response to iC3b-opsonized target cells. J. Immunol. 162:1999;2281-2290.
    • (1999) J. Immunol. , vol.162 , pp. 2281-2290
    • Xia, Y.1    Větvička, V.2    Yan, J.3    Hanikyrova, M.4    Mayadas, T.N.5    Ross, G.D.6
  • 46
    • 0027451274 scopus 로고
    • Receptor-receptor interactions of complement receptor type 3 in neutrophil membranes
    • Petty H.R., Todd R.F. Receptor-receptor interactions of complement receptor type 3 in neutrophil membranes. J. Leukocyte Biol. 54:1993;492-494.
    • (1993) J. Leukocyte Biol. , vol.54 , pp. 492-494
    • Petty, H.R.1    Todd, R.F.2
  • 47
    • 0030566746 scopus 로고    scopus 로고
    • Where the outside meets the inside: Integrins as activators and targets of signal transduction cascades
    • Brown E., Hogg N. Where the outside meets the inside: integrins as activators and targets of signal transduction cascades. Immunol. Lett. 54:1996;189-193.
    • (1996) Immunol. Lett. , vol.54 , pp. 189-193
    • Brown, E.1    Hogg, N.2
  • 48
    • 0030965068 scopus 로고    scopus 로고
    • Signaling mechanisms and the activation of leukocyte integrins
    • Newton R.A., Thiel M., Hogg N. Signaling mechanisms and the activation of leukocyte integrins. J. Leukocyte Biol. 61:1997;422-426.
    • (1997) J. Leukocyte Biol. , vol.61 , pp. 422-426
    • Newton, R.A.1    Thiel, M.2    Hogg, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.