A new hyaluronic acid pH sensitive derivative obtained by ATRP for potential oral administration of proteins

International Journal of Pharmaceutics

Volumn 457, Issue 1, 2013, Pages 150-157

  Fiorica, Calogero ^a   Pitarresi, Giovanna ^a,b   Palumbo, Fabio Salvatore ^a   Di Stefano, Mauro ^a   Calascibetta, Filippo ^a   Giammona, Gaetano ^a,c  

^a UNIVERSITY OF PALERMO   (Italy)

^b CNR   (Italy)

^c CNR Consiglio Nazionale delle Ricerche   (Italy)

Author keywords

Chymotrypsin; ATRP; Hyaluronic acid; pH sensitivity

Indexed keywords

2 BROMO 2 METHYPROPIONIC ACID; 2,2' BIPYRIDINE; AMMONIA; CHYMOTRYPSIN A; COPOLYMER; COPPER COMPLEX; HYALURONIC ACID; METHACRYLIC ACID; PEPTIDE; PROPIONIC ACID DERIVATIVE; PROTEIN; SODIUM; SODIUM CHLORIDE; TETRABUTYL AMMONIUM SALT; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; ATOM TRANSFER RADICAL POLYMERIZATION; CATALYST; DENATURATION; DRUG DELIVERY SYSTEM; FIBROBLAST; GEL PERMEATION CHROMATOGRAPHY; MOLECULE; PH; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SOLUBILITY; STOMACH JUICE; TURBIDIMETRY;

ATRP; HYALURONIC ACID; PH SENSITIVITY; Α-CHYMOTRYPSIN;

ADMINISTRATION, ORAL; ANIMALS; CELLS, CULTURED; CHROMATOGRAPHY, GEL; CHYMOTRYPSIN; ETHYLENEDIAMINES; FIBROBLASTS; HYALURONIC ACID; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; NEPHELOMETRY AND TURBIDIMETRY; POLYMERIZATION; QUATERNARY AMMONIUM COMPOUNDS; RATS; RATS, WISTAR;

EID: 84885353253     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.09.005     Document Type: Article

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