Epigenomic mechanisms of early adversity and HPA dysfunction: Considerations for PTSD research

Frontiers in Psychiatry

Volumn 4, Issue SEP, 2013, Pages

  McGowan, Patrick O ^a,b  

^a Centre for Environmental Epigenetics and Development   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Brain development; Childhood abuse; DNA methylation; Early adversity; epigenetics; Glucocorticoid receptor; Hypothalamic pituitary adrenal axis; Stress response

Indexed keywords

GLUCOCORTICOID RECEPTOR;

BRAIN MAPPING; DENTATE GYRUS; DNA METHYLATION; ENDOCRINE DISEASE; EPIGENETICS; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HIGH THROUGHPUT SCREENING; HISTONE MODIFICATION; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMUNOPRECIPITATION; MATERNAL CARE; MOLECULAR DYNAMICS; MORPHOLOGY; NERVE CELL PLASTICITY; NONHUMAN; PARENTAL BEHAVIOR; PERINATAL STRESS; POSTTRAUMATIC STRESS DISORDER; PROMOTER REGION; PROTEIN BINDING; REVIEW; TISSUE SPECIFICITY;

EID: 84885351022     PISSN: None     EISSN: 16640640     Source Type: Journal    
DOI: 10.3389/fpsyt.2013.00110     Document Type: Review

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