GC/MS analysis of high-performance liquid chromatography fractions from Sophora flavescens and Torilis japonica extracts and their in vitro anti-neosporal effects on Neospora caninum

Journal of Veterinary Science

Volumn 14, Issue 3, 2013, Pages 241-248

  Seo, Hun Su ^a   Kim, Kyoung Hee ^b   Kim, Dae Yong ^b   Park, Bong Kyun ^b   Shin, Nam Shik ^b   Kim, Jae Hoon ^c   Youn, Heejeong ^b  

^a Pfizer Animal Health   (South Korea)

^b Seoul National University   (South Korea)

^c Jeju National University   (South Korea)

Author keywords

GC MS; HPLC; Neospora caninum; Sophora flavescens; Torilis japonica

Indexed keywords

COCCIDIOSTATIC AGENT; PLANT EXTRACT;

APIACEAE; ARTICLE; CHEMISTRY; DRUG EFFECT; FRUIT; GC/MS; GROWTH, DEVELOPMENT AND AGING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS FRAGMENTOGRAPHY; NEOSPORA; NEOSPORA CANINUM; PLANT ROOT; SOPHORA; SOPHORA FLAVESCENS; TORILIS JAPONICA;

GC/MS; HPLC; NEOSPORA CANINUM; SOPHORA FLAVESCENS; TORILIS JAPONICA;

APIACEAE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COCCIDIOSTATS; FRUIT; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; NEOSPORA; PLANT EXTRACTS; PLANT ROOTS; SOPHORA;

EID: 84885339795     PISSN: 1229845X     EISSN: 1976555X     Source Type: Journal    
DOI: 10.4142/jvs.2013.14.3.241     Document Type: Article

References (35)

1. Ammann P, Waldvogel A, Breyer I, Esposito M, Müller N, Gottstein B. The role of B- and T-cell immunity in toltrazuril-treated C57BL/6 WT, μMT and nude mice experimentally infected with Neospora caninum. Parasitol Res 2004, 93, 178-187.
2. Andina D, Bernardi MD, Del Vecchio A, Fronza G, Mellerio G, Vidari G, Vita-Finzi P. Sequiterpenes from Russula sardonia. Phytochemistry 1980, 19, 93-97.
3. Behrendt JH, Taubert A, Zahner H, Hermosilla C. Studies on synchronous egress of coccidian parasites (Neospora caninum, Toxoplasma gondii, Eimeria bovis) from bovine endothelial host cells mediated by calcium ionophore A23187. Vet Res Commun 2008, 32, 325-332.
4. Cho WI, Choi JB, Lee K, Chung MS, Pyun YR. Antimicrobial activity of torilin isolated from Torilis japonica fruit against Bacillus subtilis. J Food Sci 2008, 73, M37-46.
5. Darius AK, Mehlhorn H, Heydorn AO. Effects of toltrazuril and ponazuril on Hammondia heydorni (syn. Neospora caninum) infections in mice. Parasitol Res 2004, 92, 520-522.
6. Darkin-Rattray SJ, Gurnett AM, Myers RW, Dulski PM, Crumley TM, Allocco JJ, Cannova C, Meinke PT, Colletti SL, Bednarek MA, Singh SB, Goetz MA, Dombrowski AW, Polishook JD, Schmatz DM. Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase. Proc Natl Acad Sci U S A 1996, 93, 13143-13147.
7. Dirikolu L, Yohn R, Garrett EF, Chakkath T, Ferguson DC. Detection, quantifications and pharmacokinetics of toltrazuril sulfone (Ponazuril) in cattle. J Vet Pharmacol Ther 2009, 32, 280-288.
8. Fuchs N, Ingold K, Sonda S, Bütikofer P, Hemphill A. Detection of surface-associated and intracellular glycoconjugates and glycoproteins in Neospora caninum tachyzoites. Int J Parasitol 1999, 29, 1597-1611.
9. Fujita S. Miscellaneous contributions to the essential oils of plants from various territories. LI. On the components of essential oils of Torilis japonica (Houtt.) DC. Yakugaku Zasshi 1990, 110, 771-775.
10. Gargala G, Baishanbo A, Favennec L, François A, Ballet JJ, Rossignol JF. Inhibitory activities of epidermal growth factor receptor tyrosine kinase-targeted dihydroxyisoflavone and trihydroxydeoxybenzoin derivatives on Sarcocystis neurona, Neospora caninum, and Cryptosporidium parvum development. Antimicrob Agents Chemother 2005, 49, 4628-4634.
11. Gottstein B, Eperon S, Dai WJ, Cannas A, Hemphill A, Greif G. Efficacy of toltrazuril and ponazuril against experimental Neospora caninum infection in mice. Parasitol Res 2001, 87, 43-48.
12. Gottstein B, Razmi GR, Ammann P, Sager H, Müller N. Toltrazuril treatment to control diaplacental Neospora caninum transmission in experimentally infected pregnant mice. Parasitology 2005, 130, 41-48.
13. Haerdi C, Haessig M, Sager H, Greif G, Staubli D, Gottstein B. Humoral immune reaction of newborn calves congenitally infected with Neospora caninum and experimentally treated with toltrazuril. Parasitol Res 2006, 99, 534-540.
14. Hay WH, Shell LG, Lindsay DS, Dubey JP. Diagnosis and treatment of Neospora caninum infection in a dog. J Am Vet Med Assoc 1990, 197, 87-89.
15. Kim JH, Hwang EK, Sohn HJ, Jean YH, Yoon SS, Kim DY. Repeated bovine abortion associated with Neospora caninum in Korea. Korean J Vet Res 1998, 38, 853-858.
16. Kim SE, Kim YH, Kim YC, Lee JJ. Torilin, a sequiterpene from Torilis japonica, reverses multidrug-resistance in cancer cells. Planta Med 1998, 64, 332-334.
17. Kitajima J, Suzuki N, Satoh M, Watanabe M. Sesquiterpenoids of Torilis japonica fruit. Phytochemistry 2002, 59, 811-815.
18. Kuroyanagi M, Arakawa T, Hirayama Y, Hayashi T. Antibacterial and antiandrogen flavonoids from Sophora flavescens. J Nat Prod 1999, 62, 1595-1599.
19. Lee IK, Lee JH, Hwang EI, Yun BS. New guaiane sesquiterpenes from the fruits of Torilis japonica. Chem Pharm Bull 2008, 56, 1483-1485.
20. Lindsay DS, Butler JM, Rippey NS, Blagburn BL. Demonstration of synergistic effects of sulfonamides and dihydrofolate reductase/thymidylate synthase inhibitors against Neospora caninum tachyzoites in cultured cells, and characterization of mutants resistant to pyrimethamine. Am J Vet Res 1996, 57, 68-72.
21. Lindsay DS, Dubey JP. Effects of sulfadiazine and amprolium on Neospora caninum (Protozoa: Apicomplexa) infections in mice. J Parasitol 1990, 76, 177-179.
22. Matsumura T, Kasai M, Hayashi T, Arisawa M, Momose Y, Arai I, Amagaya S, Komatsu Y. α-Glucosidase inhibitors from Paraguayan natural medicine, Ñangapiry, the leaves of Eugenia uniflora. Pharm Biol 2000, 38, 302-307.
23. Mitchell SM, Zajac AM, Davis WL, Kennedy TJ, Lindsay DS. The effects of ponazuril on development of apicomplexans in vitro. J Eukaryot Microbiol 2005, 52, 231-235.
24. Ogunwande IA, Olawore NO, Ekundayo O, Walker TM, Schmidt JM, Setzer WN. Studies on essential oils composition, antibacterial and antitoxicity of Eugenia unifera L. Int J Aromatherapy 2005, 15, 147-152.
25. Park SJ, Nam KW, Lee HJ, Cho EY, Koo U, Mar W. Neuroprotective effects of an alkaloid-free ethyl acetate extract from the root of Sophora flavescens Ait. against focal cerebral ischemia in rats. Phytomedicine 2009, 16, 1042-1051.
26. Piao XL, Piao XS, Kim SW, Park JH, Kim HY, Cai SQ. Identification and characterization of antioxidants from Sophora flavescens. Biol Pharm Bull 2006, 29, 1911-1915.
27. Strohbusch M, Müller N, Hemphill A, Greif G, Gottstein B. NcGRA2 as a molecular target to assess the parasiticidal activity of toltrazuril against Neospora caninum. Parasitology 2008, 135, 1065-1073.
28. Strohbusch M, Müller N, Hemphill A, Krebber R, Greif G, Gottstein B. Toltrazuril treatment of congenitally acquired Neospora caninum infection in newborn mice. Parasitol Res 2009, 104, 1335-1343.
29. Terada M, Sano M, Ishii AI, Kino H, Fukushima S, Noro T. Studies on chemotherapy of parasitic helminths (IV). Effects of alkaloids from Sophora flavescens on the motility of parasitic helminths and isolated host tissues (author's transl). Nihon Yakurigaku Zasshi (Japanese) 1982, 79, 105-111.
30. Yang FQ, Li SP, Chen Y, Lao SC, Wang YT, Dong TTX, Tsim KWK. Identification and quantitation of eleven sesquiterpenes in three species of Curcuma rhizomes by pressurized liquid extraction and gas chromatography-mass spectrometry. J Pharm Biomed Anal 2005, 39, 552-558.
31. Yang X, Baburin I, Plitzko I, Hering S, Hamburger M. HPLC-based activity profiling for GABAA receptor modulators from the traditional Chinese herbal drug Kushen (Sophora flavescens root). Mol Divers 2011, 15, 361-372.
32. Ye G, Zhu HY, Li ZX, Ma CH, Fan MS, Sun ZL, Huang CG. LC-MS characterization of efficacy substances in serum of experimental animals treated with Sophora flavescens extracts. Biomed Chromatogr 2007, 21, 655-660.
33. Youn HJ, Noh JW. Screening of the anticoccidial effects of herb extracts against Eimeria tenella. Vet Parasitol 2001, 96, 257-263.
34. Youn HJ, Lakritz J, Kim DY, Rottinghaus GE, Marsh AE. Anti-protozoal efficacy of medicinal herb extracts against Toxoplasma gondii and Neospora caninum. Vet Parasitol 2003, 116, 7-14.
35. Youn HJ, Lakritz J, Rottinghaus GE, Seo HS, Kim DY, Cho MH, Marsh AE. Anti-protozoa efficacy of high performance liquid chromatography fractions of Torilis japonica and Sophora flavescens extracts on Neospora caninum and Toxoplasma gondii. Vet Parasitol 2004, 125, 409-414.