Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors

Biochemical Pharmacology

Volumn 86, Issue 6, 2013, Pages 791-799

  Inserra, Marco C ^a   Kompella, Shiva N ^a   Vetter, Irina ^a   Brust, Andreas ^a   Daly, Norelle L ^a,c   Cuny, Hartmut ^b   Craik, David J ^a   Alewood, Paul F ^a   Adams, David J ^b   Lewis, Richard J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b RMIT UNIVERSITY   (Australia)

^c JAMES COOK UNIVERSITY   (Australia)

Author keywords

Conus limpusi; Electrophysiology; FLIPR; Nicotinic acetylcholine receptor; NMR structure; conotoxin

Indexed keywords

ALPHA CONOTOXIN LSIA; BUNGAROTOXIN RECEPTOR; CONOTOXIN; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA3ALPHA5BETA2; NICOTINIC RECEPTOR ALPHA3BETA2; NICOTINIC RECEPTOR ALPHA4BETA2; UNCLASSIFIED DRUG;

ARTICLE; CARBOXYLATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CONUS LIMPUSI; CONUS SNAIL; DISULFIDE BOND; DRUG ACTIVITY; DRUG ISOLATION; HUMAN; HUMAN CELL; IC 50; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; REDUCTION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 84885190747     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.07.016     Document Type: Article

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