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Volumn 33, Issue 10, 2013, Pages 1536-1548

Loss of exon 4 in a human T-cell factor-4 isoform promotes hepatic tumourigenicity

Author keywords

Exon 4; Hepatocellular carcinoma; Isoform; T cell factor 4; Wnt

Indexed keywords

BETA CATENIN; DOXORUBICIN; FLUOROURACIL; ISOPROTEIN; MESSENGER RNA; T CELL FACTOR PROTEIN; T CELL FACTOR PROTEIN 4C; T CELL FACTOR PROTEIN 4D; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 84885180273     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.12189     Document Type: Article
Times cited : (9)

References (36)
  • 1
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006; 127: 469-80.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 2
    • 77954112841 scopus 로고    scopus 로고
    • Epigenetic disruption of the WNT/beta-catenin signaling pathway in human cancers
    • Ying Y, Tao Q. Epigenetic disruption of the WNT/beta-catenin signaling pathway in human cancers. Epigenetics 2009; 4: 307-12.
    • (2009) Epigenetics , vol.4 , pp. 307-312
    • Ying, Y.1    Tao, Q.2
  • 3
    • 34250020201 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: epidemiology and molecular carcinogenesis
    • El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 2007; 132: 2557-76.
    • (2007) Gastroenterology , vol.132 , pp. 2557-2576
    • El-Serag, H.B.1    Rudolph, K.L.2
  • 4
    • 32844454531 scopus 로고    scopus 로고
    • Wnt/Frizzled signaling in hepatocellular carcinoma
    • Lee HC, Kim M, Wands JR. Wnt/Frizzled signaling in hepatocellular carcinoma. Front Biosci 2006; 11: 1901-15.
    • (2006) Front Biosci , vol.11 , pp. 1901-1915
    • Lee, H.C.1    Kim, M.2    Wands, J.R.3
  • 5
    • 79952043062 scopus 로고    scopus 로고
    • Beta-catenin signaling, liver regeneration and hepatocellular cancer: sorting the good from the bad
    • Nejak-Bowen KN, Monga SP. Beta-catenin signaling, liver regeneration and hepatocellular cancer: sorting the good from the bad. Semin Cancer Biol 2011; 21: 44-58.
    • (2011) Semin Cancer Biol , vol.21 , pp. 44-58
    • Nejak-Bowen, K.N.1    Monga, S.P.2
  • 6
    • 40949086754 scopus 로고    scopus 로고
    • Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells
    • Kim M, Lee HC, Tsedensodnom O, et al. Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/beta-catenin signaling pathway in hepatocellular carcinoma cells. J Hepatol 2008; 48: 780-91.
    • (2008) J Hepatol , vol.48 , pp. 780-791
    • Kim, M.1    Lee, H.C.2    Tsedensodnom, O.3
  • 7
    • 79952443282 scopus 로고    scopus 로고
    • Identification of T-cell factor-4 isoforms that contribute to the malignant phenotype of hepatocellular carcinoma cells
    • Tsedensodnom O, Koga H, Rosenberg SA, et al. Identification of T-cell factor-4 isoforms that contribute to the malignant phenotype of hepatocellular carcinoma cells. Exp Cell Res 2011; 317: 920-31.
    • (2011) Exp Cell Res , vol.317 , pp. 920-931
    • Tsedensodnom, O.1    Koga, H.2    Rosenberg, S.A.3
  • 9
    • 5144226941 scopus 로고    scopus 로고
    • Functional consequences of frizzled-7 receptor overexpression in human hepatocellular carcinoma
    • Merle P, de la Monte S, Kim M, et al. Functional consequences of frizzled-7 receptor overexpression in human hepatocellular carcinoma. Gastroenterology 2004; 127: 1110-22.
    • (2004) Gastroenterology , vol.127 , pp. 1110-1122
    • Merle, P.1    de la Monte, S.2    Kim, M.3
  • 10
    • 79959287290 scopus 로고    scopus 로고
    • Points of therapeutic intervention along the Wnt signaling pathway in hepatocellular carcinoma
    • Nambotin SB, Wands JR, Kim M. Points of therapeutic intervention along the Wnt signaling pathway in hepatocellular carcinoma. Anticancer Agents Med Chem 2011; 11: 549-59.
    • (2011) Anticancer Agents Med Chem , vol.11 , pp. 549-559
    • Nambotin, S.B.1    Wands, J.R.2    Kim, M.3
  • 11
    • 0034719370 scopus 로고    scopus 로고
    • Transplantation of highly differentiated immortalized human hepatocytes to treat acute liver failure
    • Kobayashi N, Miyazaki M, Fukaya K, et al. Transplantation of highly differentiated immortalized human hepatocytes to treat acute liver failure. Transplantation 2000; 69: 202-7.
    • (2000) Transplantation , vol.69 , pp. 202-207
    • Kobayashi, N.1    Miyazaki, M.2    Fukaya, K.3
  • 12
    • 0027302989 scopus 로고
    • Establishment of two distinct human hepatocellular carcinoma cell lines from a single nodule showing clonal dedifferentiation of cancer cells
    • Yano H, Iemura A, Fukuda K, et al. Establishment of two distinct human hepatocellular carcinoma cell lines from a single nodule showing clonal dedifferentiation of cancer cells. Hepatology 1993; 18: 320-7.
    • (1993) Hepatology , vol.18 , pp. 320-327
    • Yano, H.1    Iemura, A.2    Fukuda, K.3
  • 13
    • 84863093416 scopus 로고    scopus 로고
    • Loss of the SxxSS motif in a human T-cell factor-4 isoform confers hypoxia resistance to liver cancer: an oncogenic switch in Wnt signaling
    • Koga H, Tsedensodnom O, Tomimaru Y, et al. Loss of the SxxSS motif in a human T-cell factor-4 isoform confers hypoxia resistance to liver cancer: an oncogenic switch in Wnt signaling. PLoS ONE 2012; 7: e39981.
    • (2012) PLoS ONE , vol.7
    • Koga, H.1    Tsedensodnom, O.2    Tomimaru, Y.3
  • 14
    • 0036148208 scopus 로고    scopus 로고
    • Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
    • Jho EH, Zhang T, Domon C, et al. Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol Cell Biol 2002; 22: 1172-83.
    • (2002) Mol Cell Biol , vol.22 , pp. 1172-1183
    • Jho, E.H.1    Zhang, T.2    Domon, C.3
  • 15
    • 0037064055 scopus 로고    scopus 로고
    • Wnt signaling protects 3T3-L1 preadipocytes from apoptosis through induction of insulin-like growth factors
    • Longo KA, Kennell JA, Ochocinska MJ, et al. Wnt signaling protects 3T3-L1 preadipocytes from apoptosis through induction of insulin-like growth factors. J Biol Chem 2002; 277: 38239-44.
    • (2002) J Biol Chem , vol.277 , pp. 38239-38244
    • Longo, K.A.1    Kennell, J.A.2    Ochocinska, M.J.3
  • 16
    • 0035834695 scopus 로고    scopus 로고
    • Differential modulation of transcriptional activity of estrogen receptors by direct protein-protein interactions with the T cell factor family of transcription factors
    • El-Tanani M, Fernig DG, Barraclough R, Green C, Rudland P. Differential modulation of transcriptional activity of estrogen receptors by direct protein-protein interactions with the T cell factor family of transcription factors. J Biol Chem 2001; 276: 41675-82.
    • (2001) J Biol Chem , vol.276 , pp. 41675-41682
    • El-Tanani, M.1    Fernig, D.G.2    Barraclough, R.3    Green, C.4    Rudland, P.5
  • 17
    • 33746218212 scopus 로고    scopus 로고
    • Repressor roles for TCF-4 and Sfrp1 in Wnt signaling in breast cancer
    • Shulewitz M, Soloviev I, Wu T, et al. Repressor roles for TCF-4 and Sfrp1 in Wnt signaling in breast cancer. Oncogene 2006; 25: 4361-9.
    • (2006) Oncogene , vol.25 , pp. 4361-4369
    • Shulewitz, M.1    Soloviev, I.2    Wu, T.3
  • 18
    • 0034678357 scopus 로고    scopus 로고
    • The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression
    • Takemaru KI, Moon RT. The transcriptional coactivator CBP interacts with beta-catenin to activate gene expression. J Cell Biol 2000; 149: 249-54.
    • (2000) J Cell Biol , vol.149 , pp. 249-254
    • Takemaru, K.I.1    Moon, R.T.2
  • 19
    • 0035312290 scopus 로고    scopus 로고
    • All Tcf HMG box transcription factors interact with Groucho-related co-repressors
    • Brantjes H, Roose J, van De Wetering M, Clevers H. All Tcf HMG box transcription factors interact with Groucho-related co-repressors. Nucleic Acids Res 2001; 29: 1410-9.
    • (2001) Nucleic Acids Res , vol.29 , pp. 1410-1419
    • Brantjes, H.1    Roose, J.2    van De Wetering, M.3    Clevers, H.4
  • 20
    • 24744435397 scopus 로고    scopus 로고
    • Mammalian Groucho homologs: redundancy or specificity?
    • Gasperowicz M, Otto F. Mammalian Groucho homologs: redundancy or specificity? J Cell Biochem 2005; 95: 670-87.
    • (2005) J Cell Biochem , vol.95 , pp. 670-687
    • Gasperowicz, M.1    Otto, F.2
  • 21
    • 18744400798 scopus 로고    scopus 로고
    • Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation
    • Daniels DL, Weis WI. Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation. Nat Struct Mol Biol 2005; 12: 364-71.
    • (2005) Nat Struct Mol Biol , vol.12 , pp. 364-371
    • Daniels, D.L.1    Weis, W.I.2
  • 22
    • 70949096837 scopus 로고    scopus 로고
    • A Wnt kinase network alters nuclear localization of TCF-1 in colon cancer
    • Najdi R, Syed A, Arce L, et al. A Wnt kinase network alters nuclear localization of TCF-1 in colon cancer. Oncogene 2009; 28: 4133-46.
    • (2009) Oncogene , vol.28 , pp. 4133-4146
    • Najdi, R.1    Syed, A.2    Arce, L.3
  • 23
    • 0033545845 scopus 로고    scopus 로고
    • The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway
    • Shtutman M, Zhurinsky J, Simcha I, et al. The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. Proc Natl Acad Sci U S A 1999; 96: 5522-7.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 5522-5527
    • Shtutman, M.1    Zhurinsky, J.2    Simcha, I.3
  • 24
    • 51249084799 scopus 로고    scopus 로고
    • Down-regulation of osteopontin suppresses growth and metastasis of hepatocellular carcinoma via induction of apoptosis
    • Zhao J, Dong L, Lu B, et al. Down-regulation of osteopontin suppresses growth and metastasis of hepatocellular carcinoma via induction of apoptosis. Gastroenterology 2008; 135: 956-68.
    • (2008) Gastroenterology , vol.135 , pp. 956-968
    • Zhao, J.1    Dong, L.2    Lu, B.3
  • 25
    • 0027980795 scopus 로고
    • Osteopontin expression and distribution in human carcinomas
    • Brown LF, Papadopoulos-Sergiou A, Berse B, et al. Osteopontin expression and distribution in human carcinomas. Am J Pathol 1994; 145: 610-23.
    • (1994) Am J Pathol , vol.145 , pp. 610-623
    • Brown, L.F.1    Papadopoulos-Sergiou, A.2    Berse, B.3
  • 26
    • 69949097533 scopus 로고    scopus 로고
    • CD24 is a novel predictor for poor prognosis of hepatocellular carcinoma after surgery
    • Yang XR, Xu Y, Yu B, et al. CD24 is a novel predictor for poor prognosis of hepatocellular carcinoma after surgery. Clin Cancer Res 2009; 15: 5518-27.
    • (2009) Clin Cancer Res , vol.15 , pp. 5518-5527
    • Yang, X.R.1    Xu, Y.2    Yu, B.3
  • 27
    • 79960006754 scopus 로고    scopus 로고
    • CD24(+) liver tumor-initiating cells drive self-renewal and tumor initiation through STAT3-mediated NANOG regulation
    • Lee TK, Castilho A, Cheung VC, et al. CD24(+) liver tumor-initiating cells drive self-renewal and tumor initiation through STAT3-mediated NANOG regulation. Cell Stem Cell 2011; 9: 50-63.
    • (2011) Cell Stem Cell , vol.9 , pp. 50-63
    • Lee, T.K.1    Castilho, A.2    Cheung, V.C.3
  • 28
    • 84863895600 scopus 로고    scopus 로고
    • Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity
    • Wu Z-Q, Brabletz T, Fearon E, et al. Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity. Proc Natl Acad Sci USA 2012; 109: 11312-7.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 11312-11317
    • Wu, Z.-Q.1    Brabletz, T.2    Fearon, E.3
  • 29
    • 68949091982 scopus 로고    scopus 로고
    • Overexpression of insulin receptor substrate-1 and hepatitis Bx genes causes premalignant alterations in the liver
    • Longato L, de la Monte S, Kuzushita N, et al. Overexpression of insulin receptor substrate-1 and hepatitis Bx genes causes premalignant alterations in the liver. Hepatology 2009; 49: 1935-43.
    • (2009) Hepatology , vol.49 , pp. 1935-1943
    • Longato, L.1    de la Monte, S.2    Kuzushita, N.3
  • 30
    • 84868292544 scopus 로고    scopus 로고
    • Functional consequences of WNT3/Frizzled 7 mediated signaling in non-transformed hepatic cells
    • Nambotin SB, Tomimaru Y, Merle P, Wands JR, Kim M. Functional consequences of WNT3/Frizzled 7 mediated signaling in non-transformed hepatic cells. Oncogenesis 2012; 1: e31.
    • (2012) Oncogenesis , vol.1
    • Nambotin, S.B.1    Tomimaru, Y.2    Merle, P.3    Wands, J.R.4    Kim, M.5
  • 31
    • 33746927884 scopus 로고    scopus 로고
    • The connection between splicing and cancer
    • Srebrow A, Kornblihtt AR. The connection between splicing and cancer. J Cell Sci 2006; 119: 2635-41.
    • (2006) J Cell Sci , vol.119 , pp. 2635-2641
    • Srebrow, A.1    Kornblihtt, A.R.2
  • 32
    • 37349089805 scopus 로고    scopus 로고
    • Insights into the connection between cancer and alternative splicing
    • Kim E, Goren A, Ast G. Insights into the connection between cancer and alternative splicing. Trends Genet 2008; 24: 7-10.
    • (2008) Trends Genet , vol.24 , pp. 7-10
    • Kim, E.1    Goren, A.2    Ast, G.3
  • 33
    • 55549143293 scopus 로고    scopus 로고
    • The emerging role of splicing factors in cancer
    • Grosso AR, Martin S, Carmo-Fonseca M. The emerging role of splicing factors in cancer. EMBO Rep 2008; 9: 1087-93.
    • (2008) EMBO Rep , vol.9 , pp. 1087-1093
    • Grosso, A.R.1    Martin, S.2    Carmo-Fonseca, M.3
  • 34
    • 38449111154 scopus 로고    scopus 로고
    • Pre-mRNA splicing aberrations and cancer
    • Pettigrew CA, Brown MA. Pre-mRNA splicing aberrations and cancer. Front Biosci 2008; 13: 1090-105.
    • (2008) Front Biosci , vol.13 , pp. 1090-1105
    • Pettigrew, C.A.1    Brown, M.A.2
  • 35
    • 77954351642 scopus 로고    scopus 로고
    • Impairment of pre-mRNA splicing in liver disease: mechanisms and consequences
    • Berasain C, Goni S, Castillo J, et al. Impairment of pre-mRNA splicing in liver disease: mechanisms and consequences. World J Gastroenterol 2010; 16: 3091-102.
    • (2010) World J Gastroenterol , vol.16 , pp. 3091-3102
    • Berasain, C.1    Goni, S.2    Castillo, J.3
  • 36
    • 0034660872 scopus 로고    scopus 로고
    • The human T-cell transcription factor-4 gene: structure, extensive characterization of alternative splicings, and mutational analysis in colorectal cancer cell lines
    • Duval A, Rolland S, Tubacher E, et al. The human T-cell transcription factor-4 gene: structure, extensive characterization of alternative splicings, and mutational analysis in colorectal cancer cell lines. Cancer Res 2000; 60: 3872-9.
    • (2000) Cancer Res , vol.60 , pp. 3872-3879
    • Duval, A.1    Rolland, S.2    Tubacher, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.