Hemoglobin-induced nitric oxide synthase overexpression and nitric oxide production contribute to blood-brain barrier disruption in the rat

Journal of Molecular Neuroscience

Volumn 51, Issue 2, 2013, Pages 352-363

  Yang, Shuo ^a   Chen, Yizhao ^a   Deng, Xinqing ^a   Jiang, Weiping ^b   Li, Bing ^c   Fu, Zhenghao ^a   Du, Mouxuan ^a   Ding, Rui ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF SOUTH CHINA   (China)

^c UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Blood brain barrier; Hemoglobin; Nitric oxide; Nitric oxide synthase; Tight junction

Indexed keywords

CLAUDIN 5; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HEMOGLOBIN; INDUCIBLE NITRIC OXIDE SYNTHASE; JUNCTIONAL ADHESION MOLECULE A; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OCCLUDIN; PROTEIN ZO1;

ARTICLE; BLOOD BRAIN BARRIER; CAUDATE NUCLEUS; CONTROLLED STUDY; IMMUNOREACTIVITY; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; TIGHT JUNCTION;

RATTUS;

ANIMALS; BLOOD-BRAIN BARRIER; CAPILLARY PERMEABILITY; HEMOGLOBINS; INFUSIONS, INTRAVENTRICULAR; IRON; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TIGHT JUNCTION PROTEINS;

EID: 84885176363     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-013-9990-y     Document Type: Article

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