Synthetic oligodeoxynucleotides containing suppressive TTAGGG motifs inhibit AIM2 inflammasome activation

Journal of Immunology

Volumn 191, Issue 7, 2013, Pages 3876-3883

  Kaminski, John J ^a   Schattgen, Stefan A ^a   Tzeng, Te Chen ^a   Bode, Christian ^b   Klinman, Dennis M ^b   Fitzgerald, Katherine A ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; DOUBLE STRANDED DNA; EXTRACHROMOSOMAL DNA; GAMMA INTERFERON INDUCIBLE PROTEIN 16; GUANOSINE; INFLAMMASOME; INTERFERON; INTERFERON STIMULATED GENE FACTOR; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NUCLEIC ACID; OLIGODEOXYNUCLEOTIDE A151; OLIGODEOXYNUCLEOTIDE DERIVATIVE; PHOSPHOROTHIOIC ACID; PROTEIN AIM2; SINGLE STRANDED DNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATHEROSCLEROSIS; AUTOIMMUNE DISEASE; CELL ACTIVATION; CELL MATURATION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOMEGALOVIRUS; CYTOSOL; DENDRITIC CELL; DNA SEQUENCE; DRUG IDENTIFICATION; ENZYME INHIBITION; IMMUNE RESPONSE; IMMUNOMODULATION; IMMUNOSTIMULATION; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; INFECTION; INNATE IMMUNITY; INTRACELLULAR SIGNALING; LUPUS VULGARIS; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN INDUCTION; PROTEIN MOTIF; RHEUMATOID ARTHRITIS; SHOCK;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CLUSTER ANALYSIS; CYTOSKELETAL PROTEINS; CYTOSOL; DNA; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; INFLAMMASOMES; MICE; NUCLEAR PROTEINS; NUCLEOTIDE MOTIFS; OLIGODEOXYRIBONUCLEOTIDES; PROTEIN BINDING; PROTEIN MULTIMERIZATION; SIGNAL TRANSDUCTION; THIONUCLEOTIDES;

EID: 84885157623     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1300530     Document Type: Article

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