An overview of PET neuroimaging

Seminars in Nuclear Medicine

Volumn 43, Issue 6, 2013, Pages 449-461

  Nasrallah, Ilya ^a   Dubroff, Jacob ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE TRANSPORTER; FLORBETAPIR F 18; FLUMAZENIL; FLUORODEOXYGLUCOSE F 18; GLUCOSE; LIGAND; NICOTINIC RECEPTOR; RADIOLIGAND; RADIOPHARMACEUTICAL AGENT;

ALZHEIMER DISEASE; AMYLOID PLAQUE; BRAIN FUNCTION; BRAIN MAPPING; BRAIN PERFUSION; DEGENERATIVE DISEASE; DEMENTIA; DIFFUSE LEWY BODY DISEASE; FRONTOTEMPORAL DEMENTIA; GLUCOSE BRAIN LEVEL; GLUCOSE METABOLISM; HUMAN; INTRACTABLE EPILEPSY; NEUROIMAGING; OUTCOME ASSESSMENT; PARKINSON DISEASE; PATHOGENESIS; POSITRON EMISSION TOMOGRAPHY; RADIOCHEMISTRY; REVIEW; TRAUMATIC BRAIN INJURY;

AMYLOID; BRAIN; DEMENTIA; EPILEPSY; HUMANS; NEUROIMAGING; POSITRON-EMISSION TOMOGRAPHY;

EID: 84885143738     PISSN: 00012998     EISSN: 15584623     Source Type: Journal    
DOI: 10.1053/j.semnuclmed.2013.06.003     Document Type: Article

References (193)

1. G.N. Holland, W.S. Moore, and R.C. Hawkes Nuclear magnetic resonance tomography of the brain J Comput Assist Tomogr 4 1980 1 3
2. F.H. Doyle, J.C. Gore, and J.M. Pennock Imaging of the brain by nuclear magnetic resonance Lancet 2 1981 53 57
3. P.F. New, W.R. Scott, and J.A. Schnur Computed tomography with the EMI scanner in the diagnosis of primary and metastatic intracranial neoplasms Radiology 114 1975 75 87
4. K.R. Davis, J.M. Taveras, and P.F. New Cerebral infarction diagnosis by computerized tomography. Analysis and evaluation of findings AJR Am J Roentgenol Radium Ther Nucl Med 124 4 1975 Aug 643 660
5. M. Reivich, D. Kuhl, and A. Wolf Measurement of local cerebral glucose metabolism in man with 18F-2-fluoro-2-deoxy-d-glucose Acta Neurol Scand Suppl 64 1977 190 191
6. C.S. Roy, and C.S. Sherrington On the regulation of the blood-supply of the brain J Physiol 11 1890 85 158 17
7. J.M. Pearce Sir Charles Scott Sherrington (1857-1952) and the synapse J Neurol Neurosurg Psychiatry 75 2004 544
8. J.C. Baron, M.G. Bousser, and D. Comar Noninvasive tomographic study of cerebral blood flow and oxygen metabolism in vivo. Potentials, limitations, and clinical applications in cerebral ischemic disorders Eur Neurol 20 1981 273 284
9. J.C. Baron, M.G. Bousser, and A. Rey Reversal of focal "misery-perfusion syndrome" by extra-intracranial arterial bypass in hemodynamic cerebral ischemia. A case study with 15O positron emission tomography Stroke 12 1981 454 459
10. C. Kennedy, M.H. Des Rosiers, and O. Sakurada Metabolic mapping of the primary visual system of the monkey by means of the autoradiographic [14C]deoxyglucose technique Proc Natl Acad Sci U S A 73 1976 4230 4234
11. D.H. Hubel, and T.N. Wiesel Receptive fields of single neurones in the cat's striate cortex J Physiol 148 1959 574 591
12. D.H. Hubel, and T.N. Wiesel Receptive fields, binocular interaction and functional architecture in the cat's visual cortex J Physiol 160 1962 106 154
13. C. Kennedy, M. Des Rosiers, and L. Sokoloff The ocular dominance columns of the striate cortex as studied by the deoxyglucose method for measurement of local cerebral glucose utilization Trans Am Neurol Assoc 100 1975 74 77
14. M.E. Raichle, M.J. Welch, and R.L. Grubb Jr. Measurement of regional substrate utilization rates by emission tomography Science 199 1978 986 987
15. J.S. Fowler, and T. Ido Initial and subsequent approach for the synthesis of 18FDG Semin Nucl Med 32 2002 6 12
16. J.H. Greenberg, M. Reivich, and A. Alavi Metabolic mapping of functional activity in human subjects with the [18F]fluorodeoxyglucose technique Science 212 1981 678 680
17. M.E. Phelps, J.C. Mazziotta, and D.E. Kuhl Tomographic mapping of human cerebral metabolism visual stimulation and deprivation Neurology 31 1981 517 529
18. H.T. Chugani, and M.E. Phelps Maturational changes in cerebral function in infants determined by 18FDG positron emission tomography Science 231 1986 840 843
19. D.E. Kuhl, E.J. Metter, W.H. Riege, and M.E. Phelps Effects of human aging on patterns of local cerebral glucose utilization determined by the [18F]fluorodeoxyglucose method J Cereb Blood Flow Metab 2 1982 163 171
20. R.C. Gur, L.H. Mozley, and P.D. Mozley Sex differences in regional cerebral glucose metabolism during a resting state Science 267 1995 528 531
21. L. Sokoloff, M. Reivich, and C. Kennedy The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: Theory, procedure, and normal values in the conscious and anesthetized albino rat J Neurochem 28 1977 897 916
22. S.C. Huang, M.E. Phelps, and E.J. Hoffman Noninvasive determination of local cerebral metabolic rate of glucose in man Am J Physiol 238 1980 E69 E82
23. M. Reivich, D. Kuhl, and A. Wolf The [18F]fluorodeoxyglucose method for the measurement of local cerebral glucose utilization in man Circ Res 44 1979 127 137
24. C.S. Patlak, R.G. Blasberg, and J.D. Fenstermacher Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data J Cereb Blood Flow Metab 3 1983 1 7
25. M.A. Mintun, M.E. Raichle, and M.R. Kilbourn A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography Ann Neurol 15 1984 217 227
26. J. Logan, J.S. Fowler, and N.D. Volkow Graphical analysis of reversible radioligand binding from time-activity measurements applied to [N-11C-methyl]-(-)-cocaine PET studies in human subjects J Cereb Blood Flow Metab 10 1990 740 747
27. J. Logan, A.P. Wolf, and C.Y. Shiue Kinetic modeling of receptor-ligand binding applied to positron emission tomographic studies with neuroleptic tracers J Neurochem 48 1987 73 83
28. Cherry SR, Sorenson J, Phelps M: Tracer kinetic modeling, in: Physics In Nuclear Medicine (ed 3). Philadelphia, PA, Saunders, 2003, pp 377-403
29. R.B. Innis, V.J. Cunningham, and J. Delforge Consensus nomenclature for in vivo imaging of reversibly binding radioligands J Cereb Blood Flow Metab 27 2007 1533 1539
30. B.S. Chang, and D.H. Lowenstein Epilepsy N Engl J Med 349 2003 1257 1266
31. Linehan C, Berg AT: Epidemiologic aspect of epilepsy, in Wylie E (ed): The Treatment of Epilespy (ed 4). Philadelphia, PA, Lippincott, Williams and Wilkins, 2006
32. J. Engel Jr. Surgery for seizures N Engl J Med 334 1996 647 652
33. A.T. Berg Identification of pharmacoresistant epilepsy Neurol Clin 27 2009 1003 1013
34. A.E. Elsharkawy, A.H. Alabbasi, and H. Pannek Long-term outcome after temporal lobe epilepsy surgery in 434 consecutive adult patients J Neurosurg 110 2009 1135 1146
35. K. Vonck, P. Boon, and M. D'Have Long-term results of vagus nerve stimulation in refractory epilepsy Seizure 8 1999 328 334
36. W. Theodore Epilepsy: Positron emission tomography R. Van Heertum, R.S. Tikofsky, M. Ichise, Functional Cerebral SPECT and PET 2010 Wolters Kluwer Health/Lippincott, Williams & Wilkins Philadelphia, PA 123 130
37. A.T. Berg, S.F. Berkovic, and M.J. Brodie Revised terminology and concepts for organization of seizures and epilepsies: Report of the ILAE Commission on Classification and Terminology, 2005-2009 Epilepsia 51 2010 676 685
38. H. Choi, R.L. Sell, and L. Lenert Epilepsy surgery for pharmacoresistant temporal lobe epilepsy: A decision analysis J Am Med Assoc 300 2008 2497 2505
39. S. Baxendale, P.J. Thompson, and J.S. Duncan Improvements in memory function following anterior temporal lobe resection for epilepsy Neurology 71 2008 1319 1325
40. J.T. Langfitt, M. Westerveld, and M.J. Hamberger Worsening of quality of life after epilepsy surgery: Effect of seizures and memory decline Neurology 68 2007 1988 1994
41. J.T. Langfitt, R.G. Holloway, and M.P. McDermott Health care costs decline after successful epilepsy surgery Neurology 68 2007 1290 1298
42. J.T. King Jr., M.R. Sperling, and A.C. Justice A cost-effectiveness analysis of anterior temporal lobectomy for intractable temporal lobe epilepsy J Neurosurg 87 1997 20 28
43. 3 Ann Neurol 8 1980 348 360
44. M.E. Newmark, W. Theodore, and R. DeLaPaz Positron emission computed tomography (PECT) in refractory complex partial seizures Trans Am Neurol Assoc 106 1981 34 37
45. D.E. Kuhl, J. Engel Jr., and M.E. Phelps Epileptic patterns of local cerebral metabolism and perfusion in man: Investigation by emission computed tomography of 18F-fluorodeoxyglucose and 13N-ammonia Trans Am Neurol Assoc 103 1978 52 53
46. J. Engel Jr., D.E. Kuhl, and M.E. Phelps Interictal cerebral glucose metabolism in partial epilepsy and its relation to EEG changes Ann Neurol 12 1982 510 517
47. J. Engel Jr., W.J. Brown, and D.E. Kuhl Pathological findings underlying focal temporal lobe hypometabolism in partial epilepsy Ann Neurol 12 1982 518 528
48. J. Engel Jr., D.E. Kuhl, and M.E. Phelps Comparative localization of epileptic foci in partial epilepsy by PCT and EEG Ann Neurol 12 1982 529 537
49. J. Engel Jr., D.E. Kuhl, and M.E. Phelps Patterns of human local cerebral glucose metabolism during epileptic seizures Science 218 1982 64 66
50. S.H. Kim, G. Zubal, and H. Blumenfeld Epilepsy localization by ictal and interictal SPECT R. Van Heertum, R.S. Tikofsky, M. Ichise, Functional Cerebral SPECT and PET Imaging 2010 Wolters Kluwer Health/Lippincott, Williams & Wilkins Philadelphia, PA 131 148
51. J. Engel Jr. Outcome with respect to epileptic seizures J. Engel Jr Surgical Treatment of the Epilepsies 1987 Raven Press New York, NY 553 571
52. N. Foldvary, B. Nashold, and E. Mascha Seizure outcome after temporal lobectomy for temporal lobe epilepsy: A Kaplan-Meier survival analysis Neurology 54 2000 630 634
53. H.G. Wieser, W.T. Blume, and D. Fish ILAE Commission Report. Proposal for a new classification of outcome with respect to epileptic seizures following epilepsy surgery Epilepsia 42 2001 282 286
54. R.P. Carne, T.J. O'Brien, and C.J. Kilpatrick MRI-negative PET-positive temporal lobe epilepsy: A distinct surgically remediable syndrome Brain 127 Pt 10 2004 2276 2285
55. R. Kuba, I. Tyrlikova, and J. Chrastina "MRI-negative PET-positive" temporal lobe epilepsy: Invasive EEG findings, histopathology, and postoperative outcomes Epilepsy Behav 22 2011 537 541
56. C. LoPinto-Khoury, M.R. Sperling, and C. Skidmore Surgical outcome in PET-positive, MRI-negative patients with temporal lobe epilepsy Epilepsia 53 2012 342 348
57. F. Chassoux, S. Rodrigo, and F. Semah FDG-PET improves surgical outcome in negative MRI Taylor-type focal cortical dysplasias Neurology 75 2010 2168 2175
58. L. Thivard, V. Bouilleret, and F. Chassoux Diffusion tensor imaging can localize the epileptogenic zone in nonlesional extra-temporal refractory epilepsies when [(18)F]FDG-PET is not contributive Epilepsy Res 97 2011 170 182
59. A.A. Cohen-Gadol, B.G. Wilhelmi, and F. Collignon Long-term outcome of epilepsy surgery among 399 patients with nonlesional seizure foci including mesial temporal lobe sclerosis J Neurosurg 104 2006 513 524
60. S. Rubi, X. Setoain, and A. Donaire Validation of FDG-PET/MRI coregistration in nonlesional refractory childhood epilepsy Epilepsia 52 2011 2216 2224
61. N. Salamon, J. Kung, and S.J. Shaw FDG-PET/MRI coregistration improves detection of cortical dysplasia in patients with epilepsy Neurology 71 2008 1594 1601
62. R. Guerrini, and C. Barba Malformations of cortical development and aberrant cortical networks: Epileptogenesis and functional organization J Clin Neurophysiol 27 2010 372 379
63. K. Benedek, C. Juhasz, and O. Muzik Metabolic changes of subcortical structures in intractable focal epilepsy Epilepsia 45 2004 1100 1105
64. T.W. Lin, M.A. de Aburto, and M. Dahlbom Predicting seizure-free status for temporal lobe epilepsy patients undergoing surgery: Prognostic value of quantifying maximal metabolic asymmetry extending over a specified proportion of the temporal lobe J Nucl Med 48 2007 776 782
65. S. Sakamoto, T. Takami, and N. Tsuyuguchi Prediction of seizure outcome following epilepsy surgery: Asymmetry of thalamic glucose metabolism and cerebral neural activity in temporal lobe epilepsy Seizure 18 2009 1 6
66. A.B. Newberg, A. Alavi, and J. Berlin Ipsilateral and contralateral thalamic hypometabolism as a predictor of outcome after temporal lobectomy for seizures J Nucl Med 41 2000 1964 1968
67. E.Y. Joo, S.B. Hong, and H.J. Han Postoperative alteration of cerebral glucose metabolism in mesial temporal lobe epilepsy Brain 128 Pt 8 2005 1802 1810
68. P.L. Pearl, K.M. Gibson, and Z. Quezado Decreased GABA-A binding on FMZ-PET in succinic semialdehyde dehydrogenase deficiency Neurology 73 2009 423 429
69. K.M. Jacobs, K.D. Graber, and V.N. Kharazia Postlesional epilepsy: The ultimate brain plasticity Epilepsia 41 suppl 6 2000 S153 S161
70. F. Marrosu, A. Serra, and A. Maleci Correlation between GABA(A) receptor density and vagus nerve stimulation in individuals with drug-resistant partial epilepsy Epilepsy Res 55 2003 59 70
71. S.L. Neese, L.K. Sherill, and A.A. Tan Vagus nerve stimulation may protect GABAergic neurons following traumatic brain injury in rats: An immunocytochemical study Brain Res 1128 2007 157 163
72. J.M. Fritschy Epilepsy, E/I Balance and GABA(A) Receptor Plasticity Front Mol Neurosci 1 2008 5
73. V. Tretter, T.C. Jacob, and J. Mukherjee The clustering of GABA(A) receptor subtypes at inhibitory synapses is facilitated via the direct binding of receptor alpha 2 subunits to gephyrin J Neurosci 28 2008 1356 1365
74. F. Loup, F. Picard, and V.M. Andre Altered expression of alpha3-containing GABAA receptors in the neocortex of patients with focal epilepsy Brain 129 Pt 12 2006 3277 3289
75. S. Avramescu, D.A. Nita, and I. Timofeev Neocortical post-traumatic epileptogenesis is associated with loss of GABAergic neurons J Neurotrauma 26 2009 799 812
76. T.K. Hensch, and M. Fagiolini Excitatory-inhibitory balance and critical period plasticity in developing visual cortex Prog Brain Res 147 2005 115 124
77. E.G. Jones Cortical and subcortical contributions to activity-dependent plasticity in primate somatosensory cortex Ann Rev Neurosci 23 2000 1 37
78. C. Juhasz, D.C. Chugani, and O. Muzik Relationship of flumazenil and glucose PET abnormalities to neocortical epilepsy surgery outcome Neurology 56 2001 1650 1658
79. C. Juhasz, O. Muzik, and D.C. Chugani Prolonged vigabatrin treatment modifies developmental changes of GABA(A)-receptor binding in young children with epilepsy Epilepsia 42 2001 1320 1326
80. S. Lamusuo, A. Pitkanen, and L. Jutila [11 C]Flumazenil binding in the medial temporal lobe in patients with temporal lobe epilepsy: Correlation with hippocampal MR volumetry, T2 relaxometry, and neuropathology Neurology 54 2000 2252 2260
81. M.P. Richardson, M.J. Koepp, and D.J. Brooks Benzodiazepine receptors in focal epilepsy with cortical dysgenesis: An 11C-flumazenil PET study Ann Neurol 40 1996 188 198
82. I. Savic, S. Pauli, and J.O. Thorell In vivo demonstration of altered benzodiazepine receptor density in patients with generalised epilepsy J Neurol Neurosurg Psychiatry 57 1994 797 804
83. T. Shiga, K. Ikoma, and C. Katoh Loss of neuronal integrity: A cause of hypometabolism in patients with traumatic brain injury without MRI abnormality in the chronic stage Eur J Nucl Med Mol Imaging 33 2006 817 822
84. B. Szelies, J. Sobesky, and G. Pawlik Impaired benzodiazepine receptor binding in peri-lesional cortex of patients with symptomatic epilepsies studied by [(11)C]-flumazenil PET Eur J Neurol 9 2002 137 142
85. T.R. Henry, K.A. Frey, and J.C. Sackellares In vivo cerebral metabolism and central benzodiazepine-receptor binding in temporal lobe epilepsy Neurology 43 1993 1998 2006
86. D.C. Chugani, O. Muzik, and C. Juhasz Postnatal maturation of human GABAA receptors measured with positron emission tomography Ann Neurol 49 2001 618 626
87. I. Madar, R.P. Lesser, and G. Krauss Imaging of delta- and mu-opioid receptors in temporal lobe epilepsy by positron emission tomography Ann Neurol 41 1997 358 367
88. H.S. Mayberg, B. Sadzot, and C.C. Meltzer Quantification of mu and non-mu opiate receptors in temporal lobe epilepsy using positron emission tomography Ann Neurol 30 1991 3 11
89. G. Giovacchini, M.T. Toczek, and R. Bonwetsch 5-HT 1A receptors are reduced in temporal lobe epilepsy after partial-volume correction J Nucl Med 46 2005 1128 1135
90. C.J. Liew, Y.M. Lim, and R. Bonwetsch 18F-FCWAY and 18F-FDG PET in MRI-negative temporal lobe epilepsy Epilepsia 50 2009 234 239
91. W.H. Theodore, A.R. Martinez, and O.I. Khan PET of serotonin 1A receptors and cerebral glucose metabolism for temporal lobectomy J Nucl Med 53 2012 1375 1382
92. I. Odano, A. Varrone, and I. Savic Quantitative PET analyses of regional [11C]PE2I binding to the dopamine transporter - application to juvenile myoclonic epilepsy Neuroimage 59 2012 3582 3593
93. I.Y. Yakushev, E. Dupont, and H.G. Buchholz In vivo imaging of dopamine receptors in a model of temporal lobe epilepsy Epilepsia 51 2010 415 422
94. V. Bouilleret, F. Semah, and A. Biraben Involvement of the basal ganglia in refractory epilepsy: An 18F-fluoro-L-DOPA PET study using 2 methods of analysis J Nucl Med 46 2005 540 547
95. V. Bouilleret, F. Semah, and F. Chassoux Basal ganglia involvement in temporal lobe epilepsy: A functional and morphologic study Neurology 70 2008 177 184
96. M. Fedi, S.F. Berkovic, and I.E. Scheffer Reduced striatal D1 receptor binding in autosomal dominant nocturnal frontal lobe epilepsy Neurology 71 2008 795 798
97. F. Picard, D. Bruel, and D. Servent Alteration of the in vivo nicotinic receptor density in ADNFLE patients: A PET study Brain 129 Pt 8 2006 2047 2060
98. W.H. Theodore, G. Giovacchini, and R. Bonwetsch The effect of antiepileptic drugs on 5-HT-receptor binding measured by positron emission tomography Epilepsia 47 2006 499 503
99. W.H. Theodore, E.A. Wiggs, and A.R. Martinez Serotonin 1A receptors, depression, and memory in temporal lobe epilepsy Epilepsia 53 2012 129 133
100. M.T. Toczek, R.E. Carson, and L. Lang PET imaging of 5-HT1A receptor binding in patients with temporal lobe epilepsy Neurology 60 2003 749 756
101. D.C. Chugani, H.T. Chugani, and O. Muzik Imaging epileptogenic tubers in children with tuberous sclerosis complex using alpha-[11C]methyl-L-tryptophan positron emission tomography Ann Neurol 44 1998 858 866
102. H.T. Chugani, C. Juhasz, and D.C. Chugani Increased striatal serotonin synthesis following cortical resection in children with intractable epilepsy Epilepsy Res 78 2008 124 130
103. H.T. Chugani, A. Kumar, and W. Kupsky Clinical and histopathologic correlates of 11C-alpha-methyl-L-tryptophan (AMT) PET abnormalities in children with intractable epilepsy Epilepsia 52 2011 1692 1698
104. M. Fedi, D. Reutens, and H. Okazawa Localizing value of alpha-methyl-L-tryptophan PET in intractable epilepsy of neocortical origin Neurology 57 2001 1629 1636
105. C. Juhasz, D.C. Chugani, and O. Muzik Alpha-methyl-L-tryptophan PET detects epileptogenic cortex in children with intractable epilepsy Neurology 60 2003 960 968
106. C. Juhasz, D.C. Chugani, and U.N. Padhye Evaluation with alpha-[11C]methyl-L-tryptophan positron emission tomography for reoperation after failed epilepsy surgery Epilepsia 45 2004 124 130
107. J. Natsume, N. Bernasconi, and Y. Aghakhani Alpha-[11C]methyl-L- tryptophan uptake in patients with periventricular nodular heterotopia and epilepsy Epilepsia 49 2008 826 831
108. J. Natsume, Y. Kumakura, and N. Bernasconi Alpha-[11C] methyl-l-tryptophan and glucose metabolism in patients with temporal lobe epilepsy Neurology 60 2003 756 761
109. J.H. Phi, J.C. Paeng, and H.S. Lee Evaluation of focal cortical dysplasia and mixed neuronal and glial tumors in pediatric epilepsy patients using 18F-FDG and 11C-methionine pet J Nucl Med 51 2010 728 734
110. M. Sasaki, Y. Kuwabara, and T. Yoshida Carbon-11-methionine PET in focal cortical dysplasia: A comparison with fluorine-18-FDG PET and technetium-99m-ECD SPECT J Nucl Med 39 1998 974 977
111. D.A. Groves, E.M. Bowman, and V.J. Brown Recordings from the rat locus coeruleus during acute vagal nerve stimulation in the anaesthetised rat Neurosci Lett 379 2005 174 179
112. K. Vonck, K. Van Laere, and S. Dedeurwaerdere The mechanism of action of vagus nerve stimulation for refractory epilepsy: The current status J Clin Neurophysiol 18 2001 394 401
113. P.K. Panegyres, J.M. Rogers, and M. McCarthy Fluorodeoxyglucose-Positron Emission Tomography in the differential diagnosis of early-onset dementia: A prospective, community-based study BMC Neurol 9 2009 41
114. D.H. Silverman, G.W. Small, and C.Y. Chang Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome J Am Med Assoc 286 2001 2120 2127 [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.]
115. R. Ossenkoppele, N.D. Prins, and Y.A.L. Pijnenburg Impact of molecular imaging on the diagnostic process in a memory clinic Alzheimer Demen 2012
116. D.S. Karow, L.K. McEvoy, and C. Fennema-Notestine Relative capability of MR imaging and FDG PET to depict changes associated with prodromal and early Alzheimer disease Radiology 256 2010 932 942 [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.]
117. W.S. Liang, E.M. Reiman, and J. Valla Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons Proc Natl Acad Sci U S A 105 2008 4441 4446 [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't]
118. X. Liu, C. Erikson, and A. Brun Cortical synaptic changes and gliosis in normal aging, Alzheimer's disease and frontal lobe degeneration Dementia 7 1996 128 134 [Comparative Study Research Support, Non-U.S. Gov't]
119. B.H. Anderton, L. Callahan, and P. Coleman Dendritic changes in Alzheimer's disease and factors that may underlie these changes Prog Neurobiol 55 1998 595 609 [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review]
120. Y. Zhou, J.H. Dougherty Jr., and K.F. Hubner Abnormal connectivity in the posterior cingulate and hippocampus in early Alzheimer's disease and mild cognitive impairment Alzheimers Dement 4 2008 265 270 [Research Support, Non-U.S. Gov't]
121. G.M. McKhann, D.S. Knopman, and H. Chertkow The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease Alzheimers Dement 7 2011 263 269 [Consensus Development Conference, NIH Research Support, Non-U.S. Gov't]
122. A.F. Jorm, and D. Jolley The incidence of dementia: A meta-analysis Neurology 51 1998 728 733 [Meta-Analysis]
123. S.S. Mirra, A. Heyman, and D. McKeel The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease Neurology 41 1991 479 486 [Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.]
124. R.S. Wilson, D.R. Weir, and S.E. Leurgans Sources of variability in estimates of the prevalence of Alzheimer's disease in the United States Alzheimers Dement 7 2011 74 79 [Research Support, N.I.H., Extramural]
125. C.R. Jack Jr., H.J. Wiste, and P. Vemuri Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer's disease Brain 133 2010 3336 3348 [Comparative Study Research Support, N.I.H., Extramural]
126. M.S. Albert, S.T. DeKosky, and D. Dickson The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease Alzheimer Demen 7 2011 270 279
127. R.S. Wilson, L.E. Sue, and P.a.t.r.i.c.i.a.A. Boyle Cognitive decline in prodromal Alzheimer disease and mild cognitive impairment Arch Neurol 68 2011 351 356
128. B.L. Plassman, K.M. Langa, and G.G. Fisher Prevalence of cognitive impairment without dementia in the United States Ann Intern Med 148 2008 427 434 [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't]
129. R.C. Petersen, and G.E. Smith Mild cognitive impairment: Clinical characterization and outcome Arch Neurol 56 1999 303 308 [Research Support, U.S. Gov't, P.H.S.]
130. S. Gauthier, B. Reisberg, and M. Zaudig Mild cognitive impairment Lancet 367 2006 1262 1270
131. R.C. Petersen, and C.R. Jack Jr. Imaging and biomarkers in early Alzheimer's disease and mild cognitive impairment Clin Pharmacol Ther 86 2009 438 441 [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't]
132. W.E. Klunk Amyloid imaging as a biomarker for cerebral beta-amyloidosis and risk prediction for Alzheimer dementia Neurobiol Aging 32 suppl 1 2011 S20 S36 [Research Support, N.I.H., Extramural Review]
133. R.A. Sperling, P.S. Aisen, and LA Beckett Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease Alzheimers Dement 7 2011 280 292 [Consensus Development Conference, NIH Research Support, Non-U.S. Gov't]
134. J.M. Hoffman, K.A. Welsh-Bohmer, and M. Hanson FDG PET imaging in patients with pathologically verified dementia J Nucl Med 41 2000 1920 1928 [Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.]
135. L. Mosconi, W.H. Tsui, and K. Herholz Multicenter standardized 18F-FDG PET diagnosis of mild cognitive impairment, Alzheimer's disease, and other dementias J Nucl Med 49 2008 390 398 [Multicenter Study Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't]
136. A. Drzezga, N. Lautenschlager, and H. Siebner Cerebral metabolic changes accompanying conversion of mild cognitive impairment into Alzheimer's disease: A PET follow-up study Eur J Nucl Med Mol Imaging 30 2003 1104 1113 [Clinical Trial Comparative Study Controlled Clinical Trial]
137. S.M. Landau, D. Harvey, and C.M. Madison Associations between cognitive, functional, and FDG-PET measures of decline in AD and MCI Neurobiol Aging 32 2011 1207 1218
138. M.B. Patwardhan, D.C. McCrory, and D.B. Matchar Alzheimer disease: Operating characteristics of PET - A meta-analysis Radiology 231 2004 73 80 [Meta-Analysis Research Support, U.S. Gov't, P.H.S. Review]
139. W. Jagust, B. Reed, and D. Mungas What does fluorodeoxyglucose PET imaging add to a clinical diagnosis of dementia? Neurology 69 2007 871 877 [Comparative Study Evaluation Studies Research Support, N.I.H., Extramural]
140. S. Zhang, D. Han, and X. Tan Diagnostic accuracy of 18 F-FDG and 11 C-PIB-PET for prediction of short-term conversion to Alzheimer's disease in subjects with mild cognitive impairment Int J Clin Pract 66 2012 185 198 [Evaluation Studies Meta-Analysis Review]
141. R. Laforce Jr., J.P. Buteau, and N. Paquet The value of PET in mild cognitive impairment, typical and atypical/unclear dementias: A retrospective memory clinic study Am J Alzheimers Dis Other Demen 25 2010 Jun 324 332 [Research Support, Non-U.S. Gov't]
142. W.J. Jagust, S.M. Landau, and L.M. Shaw Relationships between biomarkers in aging and dementia Neurology 73 2009 1193 1199
143. R.Y. Lo, A.E. Hubbard, and L.M. Shaw Longitudinal change of biomarkers in cognitive decline Arch Neurol 68 2011 1257 1266 [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't]
144. I.G. McKeith Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): Report of the Consortium on DLB International Workshop J Alzheimers Dis 9 suppl 3 2006 417 423 [Congresses]
145. I.G. McKeith, D. Galasko, and K. Kosaka Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): Report of the consortium on DLB international workshop Neurology 47 1996 1113 1124 [Guideline Practice Guideline Research Support, Non-U.S. Gov't Review]
146. D. Weisman, and I. McKeith Dementia with Lewy bodies Semin Neurol 27 2007 42 47 [Review]
147. S. Minoshima, N.L. Foster, and A.A. Sima Alzheimer's disease versus dementia with Lewy bodies: Cerebral metabolic distinction with autopsy confirmation Ann Neurol 50 2001 358 365 [Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.]
148. E. Ratnavalli, C. Brayne, and K. Dawson The prevalence of frontotemporal dementia Neurology 58 2002 1615 1621 [Research Support, Non-U.S. Gov't]
149. R.E. Seltman, and B.R. Matthews Frontotemporal lobar degeneration: Epidemiology, pathology, diagnosis and management CNS Drugs 26 2012 841 870 [Research Support, N.I.H., Extramural, Review]
150. J. Diehl-Schmid, T. Grimmer, and A. Drzezga Decline of cerebral glucose metabolism in frontotemporal dementia: A longitudinal 18F-FDG-PET-study Neurobiol Aging 28 1 2007 42 50
151. S. Poljansky, B. Ibach, and B. Hirschberger A visual [18F]FDG-PET rating scale for the differential diagnosis of frontotemporal lobar degeneration Eur Arch Psychiatry Clin Neurosci 261 2011 433 446
152. P.J. Nestor, T.D. Fryer, and J.R. Hodges Declarative memory impairments in Alzheimer's disease and semantic dementia Neuroimage 30 2006 1010 1020
153. K.B. Womack, R. Diaz-Arrastia, and H.J. Aizenstein Temporoparietal hypometabolism in frontotemporal lobar degeneration and associated imaging diagnostic errors Arch Neurol 68 2011 329 337 [Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't]
154. K. Rockwood, C. Wentzel, and V. Hachinski Prevalence and outcomes of vascular cognitive impairment. Vascular Cognitive Impairment Investigators of the Canadian Study of Health and Aging Neurology 54 2000 447 451 [Research Support, Non-U.S. Gov't]
155. W.D. Heiss, and S. Zimmermann-Meinzingen PET imaging in the differential diagnosis of vascular dementia J Neurol Sci 322 2012 268 273
156. R. Mielke, K. Herholz, and M. Grond Severity of vascular dementia is related to volume of metabolically impaired tissue Arch Neurol 49 1992 909 913 [Research Support, Non-U.S. Gov't]
157. N. Kerrouche, K. Herholz, and R. Mielke 18FDG PET in vascular dementia: Differentiation from Alzheimer's disease using voxel-based multivariate analysis J Cereb Blood Flow Metab 26 2006 1213 1221 [Research Support, Non-U.S. Gov't]
158. K. Honjo, S.E. Black, and N.P. Verhoeff Alzheimer's disease, cerebrovascular disease, and the beta-amyloid cascade Can J Neurol Sci 39 2012 712 728 [Research Support, Non-U.S. Gov't Review]
159. K.E. Pike, G. Savage, and V.L. Villemagne Beta-amyloid imaging and memory in non-demented individuals: Evidence for preclinical Alzheimer's disease Brain 130 Pt 11 2007 2837 2844 [Comparative Study Research Support, Non-U.S. Gov't]
160. W.E. Klunk, H. Engler, and A. Nordberg Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B Ann Neurol 55 2004 306 319 [Comparative Study, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.]
161. M.D. Ikonomovic, W.E. Klunk, and E.E. Abrahamson Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease Brain 131 Pt 6 2008 1630 1645 [Case Reports, Comparative Study, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.]
162. S.M. Landau, C. Breault, and A.D. Joshi Amyloid-beta imaging with Pittsburgh compound B and florbetapir: Comparing radiotracers and quantification methods J Nucl Med 54 2013 70 77 [Comparative Study, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't]
163. C.M. Clark, M.J. Pontecorvo, and T.G. Beach Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: A prospective cohort study Lancet Neurol 11 2012 669 678
164. J. Lister-James, M.J. Pontecorvo, and C. Clark Florbetapir f-18: A histopathologically validated Beta-amyloid positron emission tomography imaging agent Semin Nucl Med 41 2011 300 304 [Validation Studies]
165. S.R. Choi, G. Golding, and Z. Zhuang Preclinical properties of 18F-AV-45: A PET agent for Abeta plaques in the brain J Nucl Med 50 2009 1887 1894 [Research Support, N.I.H., Extramural]
166. A.S. Fleisher, K. Chen, and X. Liu Using positron emission tomography and florbetapir F18 to image cortical amyloid in patients with mild cognitive impairment or dementia due to Alzheimer disease Arch Neurol 68 2011 1404 1411 [Comparative StudyResearch Support, Non-U.S. Gov't]
167. C.R. Jack Jr., V.J. Lowe, and S.D. Weigand Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: Implications for sequence of pathological events in Alzheimer's disease Brain 132 Pt 5 2009 1355 1365 [Comparative Study Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't]
168. V.L. Villemagne, M.T. Fodero-Tavoletti, and K.E. Pike The ART of loss: Abeta imaging in the evaluation of Alzheimer's disease and other dementias Mol Neurobiol 38 2008 1 15 [Research Support, Non-U.S. Gov'tReview]
169. K.A. Johnson, S. Minoshima, and N.I. Bohnen Appropriate Use Criteria for Amyloid PET: A Report of the Amyloid Imaging Task Force, the Society of Nuclear Medicine and Molecular Imaging, and the Alzheimer's Association J Nucl Med 54 2013 476 490
170. M. Grundman, A. Dibernardo, and N. Raghavan 2012: A watershed year for Alzheimer's disease research J Nutr Health Aging 17 2013 51 53
171. C.R. Jack, H.J. Wiste, and T.G. Lesnick Brain β-amyloid load approaches a plateau Neurology 80 2013 890 896
172. E.R. Dorsey, R. Constantinescu, and J.P. Thompson Projected number of people with Parkinson disease in the most populous nations, 2005 through 2030 Neurology 68 2007 384 386
173. J. Jankovic Parkinson's disease: Clinical features and diagnosis J Neurol Neurosurg Psychiatry 79 2008 368 376
174. V.L. Marshall, C.B. Reininger, and M. Marquardt Parkinson's disease is overdiagnosed clinically at baseline in diagnostically uncertain cases: A 3-year European multicenter study with repeat [123I]FP-CIT SPECT Mov Disord 24 2009 500 508
175. I. McKeith, J. O'Brien, and Z. Walker Sensitivity and specificity of dopamine transporter imaging with 123I-FP-CIT SPECT in dementia with Lewy bodies: A phase III, multicentre study Lancet Neurol 6 2007 305 313
176. J.T. O'Brien, S. Colloby, and J. Fenwick Dopamine transporter loss visualized with FP-CIT SPECT in the differential diagnosis of dementia with Lewy bodies Arch Neurol 61 2004 919 925
177. M.R. Kilbourn, J.N. DaSilva, and K.A. Frey In vivo imaging of vesicular monoamine transporters in human brain using [11C]tetrabenazine and positron emission tomography J Neurochem 60 1993 2315 2318
178. N.I. Bohnen, R.L. Albin, and R.A. Koeppe Positron emission tomography of monoaminergic vesicular binding in aging and Parkinson disease J Cereb Blood Flow Metab 26 2006 1198 1212
179. R.A. Koeppe, S. Gilman, and A. Joshi 11C-DTBZ and 18F-FDG PET measures in differentiating dementias J Nucl Med 46 2005 936 944
180. N. Okamura, V.L. Villemagne, and J. Drago In vivo measurement of vesicular monoamine transporter type 2 density in Parkinson disease with (18)F-AV-133 J Nucl Med 51 2010 223 228
181. V.L. Villemagne, N. Okamura, and S. Pejoska Differential diagnosis in Alzheimer's disease and dementia with Lewy bodies via VMAT2 and amyloid imaging Neurodegener Dis 10 2012 161 165
182. R.C. Hall, and M.J. Chapman Definition, diagnosis, and forensic implications of postconcussional syndrome Psychosomatics 46 2005 195 202 [Review]
183. A.C. McKee, T.D. Stein, and C.J. Nowinski The spectrum of disease in chronic traumatic encephalopathy Brain 136 Pt 1 2013 43 64 [Research Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.]
184. N. Hattori, S.C. Huang, and H.M. Wu Acute changes in regional cerebral (18)F-FDG kinetics in patients with traumatic brain injury J Nucl Med 45 2004 775 783 [Research Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.]
185. H.M. Wu, S.C. Huang, and N. Hattori Selective metabolic reduction in gray matter acutely following human traumatic brain injury J Neurotrauma 21 2004 149 161 [Research Support, U.S. Gov't, P.H.S.]
186. R.M. Ruff, J.A. Crouch, and A.I. Troster Selected cases of poor outcome following a minor brain trauma: Comparing neuropsychological and positron emission tomography assessment Brain Inj 8 1994 297 308
187. H. Gross, A. Kling, and G. Henry Local cerebral glucose metabolism in patients with long-term behavioral and cognitive deficits following mild traumatic brain injury J Neuropsychiatry Clin Neurosci 8 1996 324 334 [Clinical Trial]
188. T. Kato, N. Nakayama, and Y. Yasokawa Statistical image analysis of cerebral glucose metabolism in patients with cognitive impairment following diffuse traumatic brain injury J Neurotrauma 24 2007 919 926
189. J. Garcia-Panach, N. Lull, and J.J. Lull A voxel-based analysis of FDG-PET in traumatic brain injury: Regional metabolism and relationship between the thalamus and cortical areas J Neurotrauma 28 2011 1707 1717
190. A. Lupi, G. Bertagnoni, and A. Borghero Relative hypermetabolism of vermis cerebelli in traumatic brain injured patients studied with 18FDG PET: A descriptor of brain damage and a possible predictor of outcome Curr Radiopharm 4 2011 167 175
191. L.C. de Souza, S. Lehericy, and B. Dubois Neuroimaging in dementias Curr Opin Psychiatry 25 2012 473 479 [Research Support, Non-U.S. Gov't Review]
192. A.C. McKee, R.C. Cantu, and C.J. Nowinski Chronic traumatic encephalopathy in athletes: Progressive tauopathy after repetitive head injury J Neuropathol Exp Neurol 68 2009 709 735 [Case Reports Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S., Review]
193. GW Small, V Kepe, and P Siddarth PET scanning of brain tau in retired national football league players: Preliminary findings Am J Geriatr Psychiatry 21 2013 138 144