Prolonged vigabatrin treatment modifies developmental changes of GABAA-receptor binding in young children with epilepsy

Epilepsia

Volumn 42, Issue 10, 2001, Pages 1320-1326

  Juhász, Csaba ^a   Muzik, Otto ^a,b   Chugani, Diane C ^c   Shen, Chengang ^a   Janisse, James ^a   Chugani, Harry T ^b  

^a Department of Pediatrics ^*  (United States)

^b CHILDREN'S HOSPITAL OF MICHIGAN   (United States)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Development; Epilepsy; GABAA receptors; PET; Vigabatrin

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; CARBAMAZEPINE; CARBON 11; ETHOSUXIMIDE; FELBAMATE; FLUMAZENIL; GABAPENTIN; LAMOTRIGINE; PHENYTOIN; TOPIRAMATE; VALPROIC ACID; VIGABATRIN;

AGE; ARTICLE; BRAIN DEVELOPMENT; CEREBELLUM; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG EFFECT; DRUG MECHANISM; FEMALE; GABAERGIC SYSTEM; HUMAN; INTRACTABLE EPILEPSY; LONG TERM CARE; MALE; NERVE CELL PLASTICITY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RECEPTOR BINDING; THALAMUS;

AGE FACTORS; BRAIN; BRAIN MAPPING; CARBON RADIOISOTOPES; CHILD; CHILD, PRESCHOOL; EPILEPSY; FEMALE; FLUMAZENIL; HUMANS; INFANT; MALE; NEURONAL PLASTICITY; RADIOLIGAND ASSAY; RECEPTORS, GABA-A; TOMOGRAPHY, EMISSION-COMPUTED; VIGABATRIN;

EID: 0035174238     PISSN: 00139580     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1528-1157.2001.05401.x     Document Type: Article

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