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Volumn 52, Issue 9, 2011, Pages 1692-1698

Clinical and histopathologic correlates of 11C-alpha-methyl-L- tryptophan (AMT) PET abnormalities in children with intractable epilepsy

Author keywords

2 18F fluoro 2 deoxy D glucose (FDG) positron emission tomography; Alpha methyl tryptophan; Cortical dysplasia; Epilepsy surgery; Malformation of cortical development

Indexed keywords

ALPHA METHYL LEVO TRYPTOPHAN C 11; TRACER; UNCLASSIFIED DRUG;

EID: 80052522265     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2011.03103.x     Document Type: Article
Times cited : (44)

References (41)
  • 4
    • 0029097764 scopus 로고
    • Comparison of the neurochemical and behavioral effects resulting from the inhibition of kynurenine hydroxylase and/or kynureninase
    • Chiarugi A, Carpenedo R, Molina MT, Mattoli L, Pellicciari R, Moroni F,. (1995) Comparison of the neurochemical and behavioral effects resulting from the inhibition of kynurenine hydroxylase and/or kynureninase. J Neurochem 65: 1176-1183.
    • (1995) J Neurochem , vol.65 , pp. 1176-1183
    • Chiarugi, A.1    Carpenedo, R.2    Molina, M.T.3    Mattoli, L.4    Pellicciari, R.5    Moroni, F.6
  • 5
    • 33750806119 scopus 로고    scopus 로고
    • Imaging of serotonin mechanisms in epilepsy
    • Chugani HT, Chugani DC,. (2005) Imaging of serotonin mechanisms in epilepsy. Epilepsy Curr 5: 201-206.
    • (2005) Epilepsy Curr , vol.5 , pp. 201-206
    • Chugani, H.T.1    Chugani, D.C.2
  • 6
    • 0033961681 scopus 로고    scopus 로고
    • α[C-11]methyl-L-tryptophan PET maps brain serotonin synthesis and Kynurenine pathway metabolism
    • Chugani DC, Muzik O,. (2000) Alpha[C-11]methyl-L-tryptophan PET maps brain serotonin synthesis and kynurenine pathway metabolism. J Cereb Blood Flow Metab 20: 2-9. (Pubitemid 30019823)
    • (2000) Journal of Cerebral Blood Flow and Metabolism , vol.20 , Issue.1 , pp. 2-9
    • Chugani, D.C.1    Muzik, O.2
  • 8
    • 9844220289 scopus 로고    scopus 로고
    • Human brain serotonin synthesis capacity measured in vivo with α-[C-11]methyl-L-tryptophan
    • Chugani DC, Muzik O, Chakraborty P, Mangner T, Chugani HT,. (1998b) Human brain serotonin synthesis capacity measured in vivo with alpha-[C-11]methyl-L- tryptophan. Synapse 28: 33-43. (Pubitemid 128770601)
    • (1998) Synapse , vol.28 , Issue.1 , pp. 33-43
    • Chugani, D.C.1    Muzik, O.2    Chakraborty, P.3    Mangner, T.4    Chugani, H.T.5
  • 15
    • 0017345053 scopus 로고
    • Daily variations of various parameters of serotonin metabolism in the rat brain. II. Circadian variations in serum and cerebral tryptophan levels: lack of correlation with 5 HT turnover
    • DOI 10.1016/0006-8993(77)90648-5
    • Hery F, Chouvet G, Kan JP, Pujol JF, Glowinski J,. (1977) Daily variations of various parameters of serotonin metabolism in the rat brain. II. Circadian variations in serum and cerebral tryptophan levels: lack of correlation with 5-HT turnover. Brain Res 123: 137-145. (Pubitemid 8051278)
    • (1977) Brain Research , vol.123 , Issue.1 , pp. 137-145
    • Hery, F.1    Chouvet, G.2    Kan, J.P.3    Pujol, J.F.4
  • 16
    • 0025218795 scopus 로고
    • Quinolinic acid concentrations in brain and cerebrospinal fluid of patients with intractable complex partial seizures
    • Heyes MP, Wyler AR, Devinsky O, Yergey JA, Markey SP, Nadi NS,. (1990) Quinolinic acid concentrations in brain and cerebrospinal fluid of patients with intractable complex partial seizures. Epilepsia 31: 172-177. (Pubitemid 20115146)
    • (1990) Epilepsia , vol.31 , Issue.2 , pp. 172-177
    • Heyes, M.P.1    Wyler, A.R.2    Devinsky, O.3    Yergey, J.A.4    Markey, S.P.5    Nadi, N.S.6
  • 22
    • 0017887867 scopus 로고
    • Stimulant and convulsive effects of kynurenines injected into brain ventricles in mice
    • Lapin IP,. (1978) Stimulant and convulsive effects of kynurenines injected into brain ventricles in mice. J Neural Transm 42: 37-43. (Pubitemid 8271036)
    • (1978) Journal of Neural Transmission - General Section , vol.42 , Issue.1 , pp. 37-43
    • Lapin, I.P.1
  • 23
    • 38449103570 scopus 로고    scopus 로고
    • Glial activation precedes seizures and hippocampal neurodegeneration in measles virus-infected mice
    • DOI 10.1111/j.1528-1167.2008.01633.x
    • Lehrmann E, Guidetti P, Love A, Williamson J, Bertram EH, Schwarcz R,. (2008) Glial activation precedes seizures and hippocampal neurodegeneration in measles virus-infected mice. Epilepsia 49 (Suppl. 2): 13-23. (Pubitemid 351143762)
    • (2008) Epilepsia , vol.49 , Issue.SUPPL. 2 , pp. 13-23
    • Lehrmann, E.1    Guidetti, P.2    Love, A.3    Williamson, J.4    Bertram, E.H.5    Schwarcz, R.6
  • 24
    • 0345125971 scopus 로고    scopus 로고
    • Noninvasive imaging of serotonin synthesis rate using PET and α-methyltryptophan in autistic children
    • Carson R.E. Daube-Witherspoon M.E. Herscovitch P. (Eds). Academic Press, San Diego
    • Muzik O, Chugani DC, Shen C, Chugani HT,. (1998) Noninvasive imaging of serotonin synthesis rate using PET and α-methyltryptophan in autistic children. In, Carson RE, Daube-Witherspoon ME, Herscovitch P, (Eds) Quantitative functional brain imaging with positron emission tomography. Academic Press, San Diego, pp. 201-206.
    • (1998) Quantitative Functional Brain Imaging with Positron Emission Tomography , pp. 201-206
    • Muzik, O.1    Chugani, D.C.2    Shen, C.3    Chugani, H.T.4
  • 26
    • 7444239057 scopus 로고    scopus 로고
    • Kynurenine administered together with probenecid markedly inhibits pentylenetetrazol-induced seizures. An electrophysiological and behavioural study
    • DOI 10.1016/j.neuropharm.2004.06.007, PII S0028390804001601
    • Nemeth H, Robotka H, Kis Z, Rozsa E, Janaky T, Somlai C, Marosi M, Farkas T, Toldi J, Vecsei L,. (2004) Kynurenine administered together with probenecid markedly inhibits pentylenetetrazol-induced seizures. An electrophysiological and behavioural study. Neuropharmacology 47: 916-925. (Pubitemid 39440985)
    • (2004) Neuropharmacology , vol.47 , Issue.6 , pp. 916-925
    • Nemeth, H.1    Robotka, H.2    Kis, Z.3    Rozsa, E.4    Janaky, T.5    Somlai, C.6    Marosi, M.7    Farkas, T.8    Toldi, J.9    Vecsei, L.10
  • 28
    • 0019967973 scopus 로고
    • An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid
    • DOI 10.1016/0006-8993(82)91048-4
    • Perkins MN, Stone TW,. (1982) An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid. Brain Res 247: 184-187. (Pubitemid 12028646)
    • (1982) Brain Research , vol.247 , Issue.1 , pp. 184-187
    • Perkins, M.N.1    Stone, T.W.2
  • 29
    • 36549071601 scopus 로고    scopus 로고
    • Innate and adaptive immunity during epileptogenesis and spontaneous seizures: Evidence from experimental models and human temporal lobe epilepsy
    • DOI 10.1016/j.nbd.2007.08.012, PII S0969996107001933
    • Ravizza T, Gagliardi B, Noe F, Boer K, Aronica E, Vezzani A,. (2008) Innate and adaptive immunity during epileptogenesis and spontaneous seizures: evidence from experimental models and human temporal lobe epilepsy. Neurobiol Dis 29: 142-160. (Pubitemid 350180489)
    • (2008) Neurobiology of Disease , vol.29 , Issue.1 , pp. 142-160
    • Ravizza, T.1    Gagliardi, B.2    Noe, F.3    Boer, K.4    Aronica, E.5    Vezzani, A.6
  • 30
    • 0027257930 scopus 로고
    • A mechanism for increased quinolinic acid formation following acute systemic immune stimulation
    • Saito K, Crowley JS, Markey SP, Heyes MP,. (1993) A mechanism for increased quinolinic acid formation following acute systemic immune stimulation. J Biol Chem 268: 15496-15503. (Pubitemid 23222041)
    • (1993) Journal of Biological Chemistry , vol.268 , Issue.21 , pp. 15496-15503
    • Saito, K.1    Crowley, J.S.2    Markey, S.P.3    Heyes, M.P.4
  • 31
    • 77955473757 scopus 로고    scopus 로고
    • Expression of the interleukin 6 system in cortical lesions from patients with tuberous sclerosis complex and focal cortical dysplasia type IIb
    • Shu HF, Zhang CQ, Yin Q, An N, Liu SY, Yang H,. (2010) Expression of the interleukin 6 system in cortical lesions from patients with tuberous sclerosis complex and focal cortical dysplasia type IIb. J Neuropathol Exp Neurol 69: 838-849.
    • (2010) J Neuropathol Exp Neurol , vol.69 , pp. 838-849
    • Shu, H.F.1    Zhang, C.Q.2    Yin, Q.3    An, N.4    Liu, S.Y.5    Yang, H.6
  • 34
    • 0025944659 scopus 로고
    • Relationship between interferon-γ, indoleamine 2,3-dioxygenase, and tryptophan catabolism
    • Taylor MW, Feng GS,. (1991) Relationship between interferon-gamma, indoleamine 2,3-dioxygenase, and tryptophan catabolism. FASEB J 5: 2516-2522. (Pubitemid 21905800)
    • (1991) FASEB Journal , vol.5 , Issue.11 , pp. 2516-2522
    • Taylor, M.W.1    Feng, G.2
  • 35
    • 0022363313 scopus 로고
    • In vivo brain dialysis of amino acids and simultaneous EEG measurements following intrahippocampal quinolinic acid injection: Evidence for a dissociation between neurochemical changes and seizures
    • DOI 10.1111/j.1471-4159.1985.tb03993.x
    • Vezzani A, Ungerstedt U, French ED, Schwarcz R,. (1985) In vivo brain dialysis of amino acids and simultaneous EEG measurements following intrahippocampal quinolinic acid injection: evidence for a dissociation between neurochemical changes and seizures. J Neurochem 45: 335-344. (Pubitemid 15233929)
    • (1985) Journal of Neurochemistry , vol.45 , Issue.2 , pp. 335-344
    • Vezzani, A.1    Ungerstedt, U.2    French, E.D.3    Schwarcz, R.4
  • 36
    • 0024441049 scopus 로고
    • Studies on the potential neurotoxic and convulsant effects of increased blood levels of quinolinic acid in rats with altered blood-brain barrier permeability
    • DOI 10.1016/0014-4886(89)90149-0
    • Vezzani A, Stasi MA, Wu HQ, Castiglioni M, Weckermann B, Samanin R,. (1989) Studies on the potential neurotoxic and convulsant effects of increased blood levels of quinolinic acid in rats with altered blood-brain barrier permeability. Exp Neurol 106: 90-98. (Pubitemid 19246455)
    • (1989) Experimental Neurology , vol.106 , Issue.1 , pp. 90-98
    • Vezzani, A.1    Stasi, M.A.2    Wu, H.Q.3    Castiglioni, M.4    Weckermann, B.5    Samanin, R.6
  • 37
    • 46049103354 scopus 로고    scopus 로고
    • The role of cytokines in the pathophysiology of epilepsy
    • Vezzani A, Balosso S, Ravizza T,. (2008) The role of cytokines in the pathophysiology of epilepsy. Brain Behav Immun 22: 797-803.
    • (2008) Brain Behav Immun , vol.22 , pp. 797-803
    • Vezzani, A.1    Balosso, S.2    Ravizza, T.3
  • 38
    • 49749094756 scopus 로고    scopus 로고
    • Alpha-methyl-l-tryptophan positron emission tomography in epilepsy with cortical developmental malformations
    • Wakamoto H, Chugani DC, Juhasz C, Muzik O, Kupsky WJ, Chugani HT,. (2008) Alpha-methyl-l-tryptophan positron emission tomography in epilepsy with cortical developmental malformations. Pediatr Neurol 39: 181-188.
    • (2008) Pediatr Neurol , vol.39 , pp. 181-188
    • Wakamoto, H.1    Chugani, D.C.2    Juhasz, C.3    Muzik, O.4    Kupsky, W.J.5    Chugani, H.T.6
  • 39
    • 0036435647 scopus 로고    scopus 로고
    • L-4-chlorokynurenine attenuates kainate-induced seizures and lesions in the rat
    • DOI 10.1006/exnr.2002.7971
    • Wu HQ, Lee SC, Scharfman HE, Schwarcz R,. (2002) L-4-chlorokynurenine attenuates kainate-induced seizures and lesions in the rat. Exp Neurol 177: 222-232. (Pubitemid 35356835)
    • (2002) Experimental Neurology , vol.177 , Issue.1 , pp. 222-232
    • Wu, H.-Q.1    Lee, S.-C.2    Scharfman, H.E.3    Schwarcz, R.4
  • 40
    • 0022354604 scopus 로고
    • Human indolylamine 2,3-dioxygenase. Its tissue distribution, and characterization of the placental enzyme
    • Yamazaki F, Kuroiwa T, Takikawa O, Kido R,. (1985) Human indolylamine 2,3-dioxygenase. Its tissue distribution, and characterization of the placental enzyme. Biochem J 230: 635-638. (Pubitemid 16236320)
    • (1985) Biochemical Journal , vol.230 , Issue.3 , pp. 635-638
    • Yamazaki, F.1    Kuroiwa, T.2    Takikawa, O.3    Kido, R.4
  • 41
    • 33644620711 scopus 로고    scopus 로고
    • In situ-produced 7-chlorokynurenate has different effects on evoked responses in rats with limbic epilepsy in comparison to naive controls
    • DOI 10.1111/j.1528-1167.2005.00281.x
    • Zhang DX, Williamson JM, Wu HQ, Schwarcz R, Bertram EH,. (2005) In situ-produced 7-chlorokynurenate has different effects on evoked responses in rats with limbic epilepsy in comparison to naive controls. Epilepsia 46: 1708-1715. (Pubitemid 44921955)
    • (2005) Epilepsia , vol.46 , Issue.11 , pp. 1708-1715
    • Zhang, D.X.1    Williamson, J.M.2    Wu, H.-Q.3    Schwarcz, R.4    Bertram, E.H.5


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