메뉴 건너뛰기




Volumn 53, Issue 2, 2013, Pages 94-101

S-Allyl cysteine improves nonalcoholic fatty liver disease in type 2 diabetes Otsuka Long-Evans Tokushima Fatty rats via regulation of hepatic lipogenesis and glucose metabolism

Author keywords

Diabetes mellitus type 2; OLETF; PPAR; S allyl cysteine; SREBP lc

Indexed keywords

CYSTEINE DERIVATIVE; HEMOGLOBIN A1C; INSULIN; LIPID PEROXIDE; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PYRUVATE DEHYDROGENASE KINASE 4; S ALLYL CYSTEINE; STEROL REGULATORY ELEMENT BINDING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRANSCRIPTION FACTOR FKHR; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 84885136780     PISSN: 09120009     EISSN: None     Source Type: Journal    
DOI: 10.3164/jcbn.13-1     Document Type: Article
Times cited : (31)

References (28)
  • 1
    • 79960029926 scopus 로고    scopus 로고
    • Systematic review: The epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults
    • Vernon G, Baranova A, Younossi ZM. Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults. Aliment Pharmacol Ther 2011; 34: 274-285.
    • (2011) Aliment Pharmacol Ther , vol.34 , pp. 274-285
    • Vernon, G.1    Baranova, A.2    Younossi, Z.M.3
  • 4
    • 84055193440 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in non-alcoholic steatohepatitis: Growing evidence of an epidemic?
    • Hashimoto E, Tokushige K. Hepatocellular carcinoma in non-alcoholic steatohepatitis: growing evidence of an epidemic? Hepatol Res 2012; 42: 1-14.
    • (2012) Hepatol Res , vol.42 , pp. 1-4214
    • Hashimoto, E.1    Tokushige, K.2
  • 5
    • 77955175149 scopus 로고    scopus 로고
    • Cellular mechanisms underlying the protective effects of preoperative feeding: A randomized study investigating muscle and liver glycogen content, mitochondrial function, gene and protein expression
    • Awad S, Constantin-Teodosiu D, Constantin D, et al. Cellular mechanisms underlying the protective effects of preoperative feeding: A randomized study investigating muscle and liver glycogen content, mitochondrial function, gene and protein expression. Ann Surg 2010; 252: 247-253.
    • (2010) Ann Surg , vol.252 , pp. 247-253
    • Awad, S.1    Constantin-Teodosiu, D.2    Constantin, D.3
  • 6
    • 41049099170 scopus 로고    scopus 로고
    • Supplementation of α-tocopherol improves cardiovascular risk factors via the insulin signalling pathway and reduction of mitochondrial reactive oxygen species in type II diabetic rats
    • DOI 10.1080/10715760801898820, PII 790767741
    • Minamiyama Y, Takemura S, Bito Y, et al. Supplementation of a-tocopherol improves cardiovascular risk factors via the insulin signalling pathway and reduction of mitochondrial reactive oxygen species in type II diabetic rats. Free Radic Res 2008; 42: 261-271. (Pubitemid 351419912)
    • (2008) Free Radical Research , vol.42 , Issue.3 , pp. 261-271
    • Minamiyama, Y.1    Takemura, S.2    Bito, Y.3    Shinkawa, H.4    Tsukioka, T.5    Nakahira, A.6    Suehiro, S.7    Okada, S.8
  • 7
    • 77952628680 scopus 로고    scopus 로고
    • Iron restriction improves type 2 diabetes mellitus in Otsuka Long-Evans Tokushima fatty rats
    • Minamiyama Y, Takemura S, Kodai S, et al. Iron restriction improves type 2 diabetes mellitus in Otsuka Long-Evans Tokushima fatty rats. Am J Physiol Endocrinol Metab 2010; 298: El 140-E1149.
    • (2010) Am J Physiol Endocrinol Metab , vol.298
    • Minamiyama, Y.1    Takemura, S.2    Kodai, S.3
  • 8
    • 0032011660 scopus 로고    scopus 로고
    • Is gene therapy for aging possible?
    • Rattan SI. Is gene therapy for aging possible? Indian J Exp Biol 1998; 36: 233-236.
    • (1998) Indian J Exp Biol , vol.36 , pp. 233-236
    • Rattan, S.I.1
  • 10
    • 0035123594 scopus 로고    scopus 로고
    • S-allylcysteine inhibits free radical production, lipid peroxidation and neuronal damage in rat brain ischemia
    • Numagami Y, Ohnishi ST. S-allylcysteine inhibits free radical production, lipid peroxidation and neuronal damage in rat brain ischemia. J Nutr 2001; 131: U00S-U05S.
    • (2001) J Nutr , vol.131
    • Numagami, Y.1    Ohnishi, S.T.2
  • 11
    • 78650217485 scopus 로고    scopus 로고
    • Beneficial effect of S-allylcysteine (SAC) on blood glucose and pancreatic antioxidant system in streptozotocin diabetic rats
    • Saravanan G, Ponmurugan P. Beneficial effect of S-allylcysteine (SAC) on blood glucose and pancreatic antioxidant system in streptozotocin diabetic rats. Plant Foods Hum Nutr 2010; 65: 374-378.
    • (2010) Plant Foods Hum Nutr , vol.65 , pp. 374-378
    • Saravanan, G.1    Ponmurugan, P.2
  • 12
    • 11144353056 scopus 로고    scopus 로고
    • Effect of five cysteine-containing compounds on three lipogenic enzymes in Balb/cA mice consuming a high saturated fat diet
    • Lin CC, Yin MC, Hsu CC, Lin MP. Effect of five cysteine-containing compounds on three lipogenic enzymes in Balb/cA mice consuming a high saturated fat diet. Lipids 2004; 39: 843-848.
    • (2004) Lipids , vol.39 , pp. 843-848
    • Lin, C.C.1    Yin, M.C.2    Hsu, C.C.3    Lin, M.P.4
  • 13
    • 84859119720 scopus 로고    scopus 로고
    • Nuclear factor icB-dependent anti-inflammatory effects of s-allyl cysteine and s-propyl cysteine in kidney of diabetic mice
    • Mong MC, Yin MC. Nuclear factor icB-dependent anti-inflammatory effects of s-allyl cysteine and s-propyl cysteine in kidney of diabetic mice. J Agric Food Chem 2012; 60: 3158-3165.
    • (2012) J Agric Food Chem , vol.60 , pp. 3158-3165
    • Mong, M.C.1    Yin, M.C.2
  • 14
    • 10044219818 scopus 로고    scopus 로고
    • Five cysteine-containing compounds delay diabetic deterioration in Balb/cA mice
    • Hsu CC, Yen HF, Yin MC, Tsai CM, Hsieh CH. Five cysteine-containing compounds delay diabetic deterioration in Balb/cA mice. J Nutr 2004; 134: 3245-3249.
    • (2004) J Nutr , vol.134 , pp. 3245-3249
    • Hsu, C.C.1    Yen, H.F.2    Yin, M.C.3    Tsai, C.M.4    Hsieh, C.H.5
  • 15
    • 79251626570 scopus 로고    scopus 로고
    • Ameliorative potential of S-allyl cysteine on oxidative stress in STZ induced diabetic rats
    • Saravanan G, Ponmurugan P. Ameliorative potential of S-allyl cysteine on oxidative stress in STZ induced diabetic rats. Chem Biol Interact 2011; 189: 100-106.
    • (2011) Chem Biol Interact , vol.189 , pp. 100-106
    • Saravanan, G.1    Ponmurugan, P.2
  • 16
    • 80052031072 scopus 로고    scopus 로고
    • Role of S6K1 in regulation of SREBPlc expression in the liver
    • Li S, Ogawa W, Emi A, et al. Role of S6K1 in regulation of SREBPlc expression in the liver. Biochem Biophys Res Commun 2011; 412: 197-202.
    • (2011) Biochem Biophys Res Commun , vol.412 , pp. 197-202
    • Li, S.1    Ogawa, W.2    Emi, A.3
  • 17
    • 0037327916 scopus 로고    scopus 로고
    • Investigation of potential mechanisms regulating protein expression of hepatic pyruvate dehydrogenase kinase isoforms 2 and 4 by fatty acids and thyroid hormone
    • DOI 10.1042/BJ20021509
    • Holness MJ, Bulmer K, Smith ND, Sugden MC. Investigation of potential mechanisms regulating protein expression of hepatic pyruvate dehydrogenase kinase isoforms 2 and 4 by fatty acids and thyroid hormone. Biochem J 2003; 369: 687-695. (Pubitemid 36246254)
    • (2003) Biochemical Journal , vol.369 , Issue.3 , pp. 687-695
    • Holness, M.J.1    Bulmer, K.2    Smith, N.D.3    Sugden, M.C.4
  • 18
    • 0037106551 scopus 로고    scopus 로고
    • Up-regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) protein expression in oxidative skeletal muscle does not require the obligatory participation of peroxisome-proliferator-activated receptor a (PPARa)
    • Holness MJ, Bulmer K, Gibbons GF, Sugden MC. Up-regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) protein expression in oxidative skeletal muscle does not require the obligatory participation of peroxisome-proliferator- activated receptor a (PPARa). Biochem J 2002; 366: 839-846.
    • (2002) Biochem J , vol.366 , pp. 839-846
    • Holness, M.J.1    Bulmer, K.2    Gibbons, G.F.3    Sugden, M.C.4
  • 20
    • 4043109947 scopus 로고    scopus 로고
    • Diverse regulation of NF-κB and peroxisome proliferator-activated receptors in murine nonalcoholic fatty liver
    • DOI 10.1002/hep.20304
    • Romics L Jr, Kodys K, Dolganiuc A, et al. Diverse regulation of NF-kB and peroxisome proliferator-activated receptors in murine nonalcoholic fatty liver. Hepatology 2004; 40: 376-385. (Pubitemid 39062855)
    • (2004) Hepatology , vol.40 , Issue.2 , pp. 376-385
    • Romics Jr., L.1    Kodys, K.2    Dolganiuc, A.3    Graham, L.4    Velayudham, A.5    Mandrekar, P.6    Szabo, G.7
  • 21
    • 0036606670 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptor-α (PPARα) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin
    • DOI 10.1042/BJ20011699
    • Sugden MC, Bulmer K, Gibbons GF, Knight BL, Holness MJ. Peroxisome-proliferator-activated receptor-a (PPARa) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin. Biochem J 2002; 364: 361-368. (Pubitemid 34620795)
    • (2002) Biochemical Journal , vol.364 , Issue.2 , pp. 361-368
    • Sugden, M.C.1    Bulmer, K.2    Gibbons, G.F.3    Knight, B.L.4    Holness, M.J.5
  • 22
    • 0034074642 scopus 로고    scopus 로고
    • Targeted upregulation of pyruvate dehydrogenase kinase (PDK)-4 in slow- twitch skeletal muscle underlies the stable modification of the regulatory characteristics of PDK induced by high-fat feeding
    • Holness MJ, Kraus A, Harris RA, Sugden MC. Targeted upregulation of pyruvate dehydrogenase kinase (PDK)-4 in slow-twitch skeletal muscle underlies the stable modification of the regulatory characteristics of PDK induced by high-fat feeding. Diabetes 2000; 49: 775-781. (Pubitemid 30339993)
    • (2000) Diabetes , vol.49 , Issue.5 , pp. 775-781
    • Holness, M.J.1    Kraus, A.2    Harris, R.A.3    Sugden, M.C.4
  • 23
    • 0034282947 scopus 로고    scopus 로고
    • Starvation increases the amount of pyruvate dehydrogenase kinase in several mammalian tissues
    • Wu P, Blair PV, Sato J, Jaskiewicz J, Popov KM, Harris RA. Starvation increases the amount of pyruvate dehydrogenase kinase in several mammalian tissues. Arch Biochem Biophys 2000; 381: 1-7.
    • (2000) Arch Biochem Biophys , vol.381 , pp. 1-7
    • Wu, P.1    Blair, P.V.2    Sato, J.3    Jaskiewicz, J.4    Popov, K.M.5    Harris, R.A.6
  • 24
    • 0031973056 scopus 로고    scopus 로고
    • Starvation and diabetes increase the amount of pyruvate dehydrogenase kinase isoenzyme 4 in rat heart
    • Wu P, Sato J, Zhao Y, Jaskiewicz J, Popov KM, Harris RA. Starvation and diabetes increase the amount of pyruvate dehydrogenase kinase isoenzyme 4 in rat heart. Biochem J1998; 329: 197-201. (Pubitemid 28022309)
    • (1998) Biochemical Journal , vol.329 , Issue.1 , pp. 197-201
    • Wu, P.1    Sato, J.2    Zhao, Y.3    Jaskiewicz, J.4    Popov, K.M.5    Harris, R.A.6
  • 25
    • 0032739720 scopus 로고    scopus 로고
    • Pyruvate dehydrogenase kinase 4 mRNA is increased in the hypertrophied ventricles of carnitine-deficient juvenile visceral steatosis (JVS) mice
    • Horiuchi M, Kobayashi K, Masuda M, Terazono H, Saheki T. Pyruvate dehydrogenase kinase 4 mRNA is increased in the hypertrophied ventricles of camitine-deficient juvenile visceral steatosis (JVS) mice. Biofactors 1999; 10: 301-309. (Pubitemid 29533845)
    • (1999) BioFactors , vol.10 , Issue.2-3 , pp. 301-309
    • Horiuchi, M.1    Kobayashi, K.2    Masuda, M.3    Terazono, H.4    Saheki, T.5
  • 26
    • 2942724616 scopus 로고    scopus 로고
    • Transcriptional regulation of pyruvate dehydrogenase kinase 4 in skeletal muscle during and after exercise
    • DOI 10.1079/PNS2004345
    • Pilegaard H, Neufer PD. Transcriptional regulation of pyruvate dehydrogenase kinase 4 in skeletal muscle during and after exercise. Proc Nutr Soc 2004; 63:221-226. (Pubitemid 38787469)
    • (2004) Proceedings of the Nutrition Society , vol.63 , Issue.2 , pp. 221-226
    • Pilegaard, H.1    Neufer, P.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.