Beneficial Effect of S-allylcysteine (SAC) on Blood Glucose and Pancreatic Antioxidant System in Streptozotocin Diabetic Rats

Plant Foods for Human Nutrition

Volumn 65, Issue 4, 2010, Pages 374-378

  Saravanan, Ganapathy ^a,b   Ponmurugan, Ponnusamy ^a,c  

^a BHARATHIAR UNIVERSITY   (India)

^b K S RANGASAMY COLLEGE OF ARTS AND SCIENCE AUTONOMOUS   (India)

^c K S RANGASAMY COLLEGE OF TECHNOLOGY   (India)

Author keywords

Antioxidants; Lipid peroxidation; S allylcysteine; Streptozotocin

Indexed keywords

ANTIDIABETIC AGENT; ANTIOXIDANT; CYSTEINE; DRUG DERIVATIVE; GLICLAZIDE; PLANT EXTRACT; S ALLYLCYSTEINE; S-ALLYLCYSTEINE; STREPTOZOCIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL; ARTICLE; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; GARLIC; GLUCOSE BLOOD LEVEL; MALE; OXIDATIVE STRESS; PANCREAS; PHYTOTHERAPY; RAT; WISTAR RAT;

ANIMALS; ANTIOXIDANTS; BLOOD GLUCOSE; CYSTEINE; DIABETES MELLITUS, EXPERIMENTAL; GARLIC; GLICLAZIDE; HYPOGLYCEMIC AGENTS; MALE; OXIDATIVE STRESS; PANCREAS; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, WISTAR; STREPTOZOCIN; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

RATTUS;

EID: 78650217485     PISSN: 09219668     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11130-010-0192-2     Document Type: Article

References (27)

1. Matsui T, Tanaka T, Tamura S, Toshima A, Matsumoto K (2007) Alphaglucosidase inhibitory profile of catechins. J Agric Food Chem 55: 99-105.
2. Wolff SP (1993) Diabetes mellitus and free radicals: transition metals and oxidative stress in the aetiology of diabetes mellitus. Br Med Bull 49: 642-652.
3. Ramachandran A, Snehalatha C, Viswanathan V (2002) Burden of type 2 diabetes and its complications-the Indian scenario. Curr Sci 83: 1471-1476.
4. Sicree R, Shaw J, Zimmet P (2006) Diabetes and impaired glucose tolerance. In: Gan D (ed) Diabetes Atlas. International Diabetes Federation. 3rd ed. International Diabetes Federation, Belgium, pp 15-103.
5. Anuradha CV, Ravikumar P (2001) Restoration on tissue antioxidants by fenugreek seeds (Trigonella foenum graecum) in alloxan-diabetic rats. Indian J Physiol Pharmacol 45: 408-420.
6. Baynes JW (1991) Role of oxidative stress in development of complications in diabetes. Diabetes 40: 405-412.
7. Oberley LW (1988) Free radicals and diabetes. Free Radic Biol Med 5: 113-118.
8. Block E (1992) The organosulfur chemistry of the genus Allium: implications for the organic chemistry of sulfur. Angew Chem Int Edition Eng 31: 1135-1178.
9. Herrera-Mundo MN, Silva-Adaya D, Maldonado PD, Santamaria A (2006) S-allylcysteine prevents the rat from 3-nitropropionic acid-induced hyperactivity early markers of oxidative stress and mitochondrial dysfunction. Neurosci Res 56: 39-44.
10. Nakagawa S, Kasuga S, Matsuura H (1989) Prevention of liver damage by aged garlic extract and its components in mice. Phytother Res 3: 50-53.
11. Kaleem M, Asif M, Ahmed Q, Bano B (2006) Antidiabetic activity of Annona squamosa extract in streptozotocin induced diabetic rats. Sing Med J 47: 670-675.
12. Saravanan G, Ponmurugan P, Senthilkumar GP, Rajarajan T (2009) Antidiabetic properties of S-allylcysteine, on streptozotocin-induced diabetes in rats. J App Biomed 7: 151-159.
13. Pulido N, Suarez A, Casanova B, Romero R, Rodriguez E, Rovira A (1997) Glyclazide treatment of streptozotocin diabetic rats restores GLUT4 protein content and basal glucose uptake in skeletal muscle. Metabolism 46: 10-13.
14. Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95: 351-358.
15. Ellman GL (1959) Tissue sulfhydryl groups. Arch Biochem Biophys 82: 70-77.
16. Misra HP, Fridovich I (1972) The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem 247: 3170-3175.
17. Takahara S, Hamilton HB, Neel JU, Kobara TY, Ogura Y, Nishimura ET (1960) Hypocatalasemia: a new genetic carrier state. J Clin Invest 39: 610-619.
18. Tomlinson KC, Gardiner SM, Hebden RA, Bennett T (1992) Functional consequences of streptozotocin-induced diabetes mellitus, with particular reference to the cardiovascular system. Pharmacol Rev 44: 103-107.
19. Spinas GA (1999) The role of nitric oxide in ß-cells. News Physiol Sci 14: 49-54.
20. Sanders RA, Rauscher FM, Watkins JB (2001) Effects of quercetin on streptozotocin-induced diabetic rats. J Biochem Mol Toxicol 15: 143-149.
21. Satheesh MA, Pari L (2004) Antioxidant effect of Boehavia diffusa L. in tissues of alloxan-induced diabetic rats. Indian J Exp Biol 42: 982-992.
22. Acworth IN, McCabe DR, Maher T (1997) The analysis of free radicals, their reaction products, and antioxidants. In: Baskin SI, Salem H (eds). Taylor and Francis, Washington, DC, pp 196-202.
23. Winterbourn C (1995) Biothiols in Health and Disease. Marcet Dekker Inc, New York, pp 117-134.
24. Loven D, Schedf H, Wilson H, Diekus M, Oberley L (1986) Effect of insulin and oral glutathione on streptozotocin induced diabetes. Diabetes 35: 503-507.
25. Sozmen BY, Sozmen B, Delen Y, Onat T (2001) Catalase/ superoxide dismutase may implicate poor glycemic control. Arch Med Res 32: 283-287.
26. Yan H, Harding JJ (1997) Glycation-induced inactivation and loss of antigenicity of catalase and superoxide dismutase. Biochem J 328: 599-603.
27. Mahmood MS, Gilani AH, Khwaja A, Rashid A, Ashfaq MK (2003) The in vitro effect of aqueous extract of Nigella sativa seeds on nitric oxide production. Phytother Res 17: 921-924.