The COX-2 selective blocker etodolac inhibits TNFα-induced apoptosis in isolated rabbit articular chondrocytes

International Journal of Molecular Sciences

Volumn 14, Issue 10, 2013, Pages 19705-19715

  Kumagai, Kousuke ^a   Kubo, Mitsuhiko ^a   Imai, Shinji ^a   Toyoda, Futoshi ^a   Maeda, Tsutomu ^a   Okumura, Noriaki ^a   Matsuura, Hiroshi ^a   Matsusue, Yoshitaka ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

Author keywords

Apoptosis; Chondrocyte; Osteoarthritis; TNF COX 2

Indexed keywords

5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; CASPASE 3; CASPASE 7; CHLORIDE ION; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; ETODOLAC; KETOROLAC; SULINDAC; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CELL MEMBRANE CONDUCTANCE; CELL MEMBRANE POTENTIAL; CELL VOLUME; CHLORIDE CURRENT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME INHIBITION; EXPOSURE; IN VITRO STUDY; MALE; MEMBRANE CURRENT; NONHUMAN; PROTEIN EXPRESSION; RABBIT;

ANIMALS; APOPTOSIS; CASPASE 3; CASPASE 7; CHLORIDES; CHONDROCYTES; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; MALE; RABBITS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84885097704     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms141019705     Document Type: Article

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