-
1
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson, J. A. et al. Embryonic stem cell lines derived from human blastocysts. Science 282, 1145-1147 (1998).
-
(1998)
Science
, vol.282
, pp. 1145-1147
-
-
Thomson, J.A.1
-
2
-
-
0034101804
-
Embryonic stem cell lines from human blastocysts: Somatic differentiation in vitro
-
Reubinoff, B. E., Pera, M. F., Fong, C. Y., Trounson, A. & Bongso, A. Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro. Nat. Biotechnol. 18, 399-404 (2000).
-
(2000)
Nat. Biotechnol
, vol.18
, pp. 399-404
-
-
Reubinoff, B.E.1
Pera, M.F.2
Fong, C.Y.3
Trounson, A.4
Bongso, A.5
-
3
-
-
15544383394
-
Embryonic stem cells: Prospects for developmental biology and cell therapy
-
Wobus, A. M. & Boheler, K. R. Embryonic stem cells: prospects for developmental biology and cell therapy. Physiol. Rev. 85, 635-678 (2005).
-
(2005)
Physiol. Rev
, vol.85
, pp. 635-678
-
-
Wobus, A.M.1
Boheler, K.R.2
-
4
-
-
79959480335
-
Potential clinical applications for human pluripotent stem cell-derived blood components
-
Kimbrel, E. A. & Lu, S. J. Potential clinical applications for human pluripotent stem cell-derived blood components. Stem Cells Int. 2011, 273076 (2011).
-
(2011)
Stem Cells Int
, vol.2011
, pp. 273076
-
-
Kimbrel, E.A.1
Lu, S.J.2
-
5
-
-
78149465975
-
A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity
-
Chia, N. Y. et al. A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity. Nature 468, 316-320 (2010).
-
(2010)
Nature
, vol.468
, pp. 316-320
-
-
Chia, N.Y.1
-
6
-
-
44649117905
-
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
-
Chen, X. et al. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133, 1106-1117 (2008).
-
(2008)
Cell
, vol.133
, pp. 1106-1117
-
-
Chen, X.1
-
7
-
-
84880766910
-
Genome-wide kinasechromatin interactions reveal the regulatory network of ERK signaling in human embryonic stem cells
-
Göke, J., Chan, Y. S., Yan, J., Vingron, M. & Ng, H. H. Genome-wide kinasechromatin interactions reveal the regulatory network of ERK signaling in human embryonic stem cells. Mol. Cell 50, 844-855 (2013).
-
(2013)
Mol. Cell
, vol.50
, pp. 844-855
-
-
Göke, J.1
Chan, Y.S.2
Yan, J.3
Vingron, M.4
Ng, H.H.5
-
8
-
-
84855278198
-
Combinatorial binding in human and mouse embryonic stem cells identifies conserved enhancers active in early embryonic development
-
Göke, J. et al. Combinatorial binding in human and mouse embryonic stem cells identifies conserved enhancers active in early embryonic development. PLoS Comput. Biol. 7, e1002304 (2011).
-
(2011)
PLoS Comput. Biol
, vol.7
-
-
Göke, J.1
-
9
-
-
40249093059
-
A core Klf circuitry regulates self-renewal of embryonic stem cells
-
Jiang, J. et al. A core Klf circuitry regulates self-renewal of embryonic stem cells. Nat. Cell Biol. 10, 353-360 (2008).
-
(2008)
Nat. Cell Biol
, vol.10
, pp. 353-360
-
-
Jiang, J.1
-
10
-
-
80052739322
-
Genomic approaches to deconstruct pluripotency
-
Loh, Y. H. et al. Genomic approaches to deconstruct pluripotency. Annu. Rev. Genom. Hum. Genet. 12, 165-185 (2011).
-
(2011)
Annu. Rev. Genom. Hum. Genet
, vol.12
, pp. 165-185
-
-
Loh, Y.H.1
-
11
-
-
70349445264
-
Systems biology of stem cell fate and cellular reprogramming
-
Macarthur, B. D., Ma'ayan, A. & Lemischka, I. R. Systems biology of stem cell fate and cellular reprogramming. Nat. Rev. Mol. Cell Biol. 10, 672-681 (2009).
-
(2009)
Nat. Rev. Mol. Cell Biol
, vol.10
, pp. 672-681
-
-
MacArthur, B.D.1
Ma'Ayan, A.2
Lemischka, I.R.3
-
12
-
-
79958252915
-
Chromatin connections to pluripotency and cellular reprogramming
-
Orkin, S. H. & Hochedlinger, K. Chromatin connections to pluripotency and cellular reprogramming. Cell 145, 835-850 (2011).
-
(2011)
Cell
, vol.145
, pp. 835-850
-
-
Orkin, S.H.1
Hochedlinger, K.2
-
13
-
-
79952660821
-
Control of the embryonic stem cell state
-
Young, R. A. Control of the embryonic stem cell state. Cell 144, 940-954 (2011).
-
(2011)
Cell
, vol.144
, pp. 940-954
-
-
Young, R.A.1
-
14
-
-
70350686165
-
Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells
-
Yuan, P. et al. Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells. Genes Dev. 23, 2507-2520 (2009).
-
(2009)
Genes Dev
, vol.23
, pp. 2507-2520
-
-
Yuan, P.1
-
15
-
-
0028314034
-
The SON gene encodes a conserved DNA binding protein mapping to human chromosome
-
Khan, I. M. et al. The SON gene encodes a conserved DNA binding protein mapping to human chromosome. Ann. Hum. Genet. 58, 25-34 (1994).
-
(1994)
Ann. Hum. Genet
, vol.58
, pp. 25-34
-
-
Khan, I.M.1
-
16
-
-
0035968208
-
Transcription repression of human hepatitis B virus genes by negative regulatory element-binding protein/SON
-
Sun, C. T. et al. Transcription repression of human hepatitis B virus genes by negative regulatory element-binding protein/SON. J. Biol. Chem. 276, 24059-24067 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 24059-24067
-
-
Sun, C.T.1
-
17
-
-
0034662774
-
Organization and conservation of the GART/SON/DONSON locus in mouse and human genomes
-
Wynn, S. L. et al. Organization and conservation of the GART/SON/DONSON locus in mouse and human genomes. Genomics 68, 57-62 (2000).
-
(2000)
Genomics
, vol.68
, pp. 57-62
-
-
Wynn, S.L.1
-
18
-
-
3342966899
-
Proteomic analysis of interchromatin granule clusters
-
Saitoh, N. et al. Proteomic analysis of interchromatin granule clusters. Mol. Biol. Cell 15, 3876-3890 (2004).
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 3876-3890
-
-
Saitoh, N.1
-
19
-
-
77955437789
-
SON is a spliceosome-associated factor required for mitotic progression
-
Huen, M. S. et al. SON is a spliceosome-associated factor required for mitotic progression. Cell Cycle 9, 2679-2685 (2010).
-
(2010)
Cell Cycle
, vol.9
, pp. 2679-2685
-
-
Huen, M.S.1
-
20
-
-
76649108893
-
Son is essential for nuclear speckle organization and cell cycle progression
-
Sharma, A., Takata, H., Shibahara, K., Bubulya, A. & Bubulya, P. A. Son is essential for nuclear speckle organization and cell cycle progression. Mol. Biol. Cell 21, 650-663 (2010).
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 650-663
-
-
Sharma, A.1
Takata, H.2
Shibahara, K.3
Bubulya, A.4
Bubulya, P.A.5
-
21
-
-
79954506151
-
SON controls cell-cycle progression by coordinated regulation of RNA splicing
-
Ahn, E. Y. et al. SON controls cell-cycle progression by coordinated regulation of RNA splicing. Mol. Cell 42, 185-198 (2011).
-
(2011)
Mol. Cell
, vol.42
, pp. 185-198
-
-
Ahn, E.Y.1
-
22
-
-
84863393044
-
Son maintains accurate splicing for a subset of human pre-mRNAs
-
Sharma, A. et al. Son maintains accurate splicing for a subset of human pre-mRNAs. J. Cell Sci. 124, 4286-4298 (2011).
-
(2011)
J. Cell Sci
, vol.124
, pp. 4286-4298
-
-
Sharma, A.1
-
23
-
-
79151470981
-
A high proliferation rate is required for cell reprogramming and maintenance of human embryonic stem cell identity
-
Ruiz, S. et al. A high proliferation rate is required for cell reprogramming and maintenance of human embryonic stem cell identity. Curr. Biol. 21, 45-52 (2011).
-
(2011)
Curr. Biol
, vol.21
, pp. 45-52
-
-
Ruiz, S.1
-
24
-
-
0030691967
-
Coupling cell division and cell death to microtubule dynamics
-
Sorger, P. K., Dobles, M., Tournebize, R. & Hyman, A. A. Coupling cell division and cell death to microtubule dynamics. Curr. Opin. Cell Biol. 9, 807-814 (1997).
-
(1997)
Curr. Opin. Cell Biol
, vol.9
, pp. 807-814
-
-
Sorger, P.K.1
Dobles, M.2
Tournebize, R.3
Hyman, A.A.4
-
25
-
-
0026583746
-
Cyclin A is required at two points in the human cell cycle
-
Pagano, M., Pepperkok, R., Verde, F., Ansorge, W. & Draetta, G. Cyclin A is required at two points in the human cell cycle. EMBO J. 11, 961-971 (1992).
-
(1992)
EMBO J.
, vol.11
, pp. 961-971
-
-
Pagano, M.1
Pepperkok, R.2
Verde, F.3
Ansorge, W.4
Draetta, G.5
-
26
-
-
34250206996
-
A ROCK inhibitor permits survival of dissociated human embryonic stem cells
-
Watanabe, K. et al. A ROCK inhibitor permits survival of dissociated human embryonic stem cells. Nat. Biotechnol. 25, 681-686 (2007).
-
(2007)
Nat. Biotechnol
, vol.25
, pp. 681-686
-
-
Watanabe, K.1
-
27
-
-
0034737439
-
Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139
-
Rogakou, E. P., Nieves-Neira, W., Boon, C., Pommier, Y. & Bonner, W. M. Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139. J. Biol. Chem. 275, 9390-9395 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 9390-9395
-
-
Rogakou, E.P.1
Nieves-Neira, W.2
Boon, C.3
Pommier, Y.4
Bonner, W.M.5
-
28
-
-
2442441507
-
Maximum entropy modeling of short sequence motifs with applications to RNA splicing signals
-
Yeo, G. & Burge, C. B. Maximum entropy modeling of short sequence motifs with applications to RNA splicing signals. J. Comput. Biol. 11, 377-394 (2004).
-
(2004)
J. Comput. Biol
, vol.11
, pp. 377-394
-
-
Yeo, G.1
Burge, C.B.2
-
29
-
-
33845895301
-
Compensatory relationship between splice sites and exonic splicing signals depending on the length of vertebrate introns
-
Dewey, C. N., Rogozin, I. B. & Koonin, E. V. Compensatory relationship between splice sites and exonic splicing signals depending on the length of vertebrate introns. BMC Genom. 7, 311-319 (2006).
-
(2006)
BMC Genom
, vol.7
, pp. 311-319
-
-
Dewey, C.N.1
Rogozin, I.B.2
Koonin, E.V.3
-
30
-
-
84861694712
-
Differential GC content between exons and introns establishes distinct strategies of splice-site recognition
-
Amit, M. et al. Differential GC content between exons and introns establishes distinct strategies of splice-site recognition. Cell Rep. 1, 543-556 (2012).
-
(2012)
Cell Rep
, vol.1
, pp. 543-556
-
-
Amit, M.1
-
31
-
-
1442311693
-
Oct-4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells
-
Hay, D. C., Sutherland, L., Clark, J. & Burdon, T. Oct-4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells. Stem Cells 22, 225-235 (2004).
-
(2004)
Stem Cells
, vol.22
, pp. 225-235
-
-
Hay, D.C.1
Sutherland, L.2
Clark, J.3
Burdon, T.4
-
32
-
-
34247197937
-
The nonsense-mediated decay RNA surveillance pathway
-
Chang, Y. F., Imam, J. S. & Wilkinson, M. F. The nonsense-mediated decay RNA surveillance pathway. Annu. Rev. Biochem. 76, 51-74 (2007).
-
(2007)
Annu. Rev. Biochem
, vol.76
, pp. 51-74
-
-
Chang, Y.F.1
Imam, J.S.2
Wilkinson, M.F.3
-
33
-
-
0035823036
-
Evidence for a pioneer round of mRNA translation: MRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20
-
Ishigaki, Y., Li, X., Serin, G. & Maquat, L. E. Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20. Cell 106, 607-617 (2001).
-
(2001)
Cell
, vol.106
, pp. 607-617
-
-
Ishigaki, Y.1
Li, X.2
Serin, G.3
Maquat, L.E.4
-
34
-
-
0742323558
-
Nonsense-mediated mRNA decay: Splicing, translation and mRNP dynamics
-
Maquat, L. E. Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics. Nat. Rev. Mol. Cell Biol. 5, 89-99 (2004).
-
(2004)
Nat. Rev. Mol. Cell Biol
, vol.5
, pp. 89-99
-
-
Maquat, L.E.1
-
35
-
-
84875784029
-
A PRC2-dependent repressive role of PRDM14 in human embryonic stem cells and induced pluripotent stem cell reprogramming
-
Chan, Y. S. et al. A PRC2-dependent repressive role of PRDM14 in human embryonic stem cells and induced pluripotent stem cell reprogramming. Stem Cells 31, 682-692 (2012).
-
(2012)
Stem Cells
, vol.31
, pp. 682-692
-
-
Chan, Y.S.1
-
36
-
-
38349172076
-
Alternative splicing minireview series: Combinatorial control facilitates splicing regulation of gene expression and enhances genome diversity
-
Fedor, M. J. Alternative splicing minireview series: combinatorial control facilitates splicing regulation of gene expression and enhances genome diversity. J. Biol. Chem. 283, 1209-1210 (2008).
-
(2008)
J. Biol. Chem
, vol.283
, pp. 1209-1210
-
-
Fedor, M.J.1
-
37
-
-
0037443035
-
Pre-mRNA splicing and human disease
-
Faustino, N. A. & Cooper, T. A. Pre-mRNA splicing and human disease. Genes Dev. 17, 419-437 (2003).
-
(2003)
Genes Dev
, vol.17
, pp. 419-437
-
-
Faustino, N.A.1
Cooper, T.A.2
-
38
-
-
35748959630
-
Alternative splicing events identified in human embryonic stem cells and neural progenitors
-
Yeo, G. W. et al. Alternative splicing events identified in human embryonic stem cells and neural progenitors. PLoS Comput. Biol. 3, 1951-1967 (2007).
-
(2007)
PLoS Comput. Biol
, vol.3
, pp. 1951-1967
-
-
Yeo, G.W.1
-
39
-
-
73449125132
-
Alternative splicing in the differentiation of human embryonic stem cells into cardiac precursors
-
Salomonis, N. et al. Alternative splicing in the differentiation of human embryonic stem cells into cardiac precursors. PLoS Comput. Biol. 5, e1000553 (2009).
-
(2009)
PLoS Comput. Biol
, vol.5
-
-
Salomonis, N.1
-
40
-
-
77953764202
-
Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation
-
Salomonis, N. et al. Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation. Proc. Natl Acad. Sci. USA 107, 10514-10519 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 10514-10519
-
-
Salomonis, N.1
-
41
-
-
59649107040
-
An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells
-
Yeo, G. W. et al. An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells. Nat. Struct. Mol. Biol. 16, 130-137 (2009).
-
(2009)
Nat. Struct. Mol. Biol
, vol.16
, pp. 130-137
-
-
Yeo, G.W.1
-
42
-
-
80052223272
-
An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming
-
Gabut, M. et al. An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming. Cell 147, 132-146 (2011).
-
(2011)
Cell
, vol.147
, pp. 132-146
-
-
Gabut, M.1
-
43
-
-
84878995293
-
MBNL proteins repress ES-cell-Specific alternative splicing and reprogramming
-
Han, H. et al. MBNL proteins repress ES-cell-Specific alternative splicing and reprogramming. Nature 498, 241-245 (2013).
-
(2013)
Nature
, vol.498
, pp. 241-245
-
-
Han, H.1
-
44
-
-
25144525014
-
Core transcriptional regulatory circuitry in human embryonic stem cells
-
Boyer, L. A. et al. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122, 947-956 (2005).
-
(2005)
Cell
, vol.122
, pp. 947-956
-
-
Boyer, L.A.1
-
45
-
-
77957139539
-
Mediator and cohesin connect gene expression and chromatin architecture
-
Kagey, M. H. et al. Mediator and cohesin connect gene expression and chromatin architecture. Nature 467, 430-435 (2010).
-
(2010)
Nature
, vol.467
, pp. 430-435
-
-
Kagey, M.H.1
-
46
-
-
3042793895
-
The E4F protein is required for mitotic progression during embryonic cell cycles
-
Le Cam, L., Lacroix, M., Ciemerych, M. A., Sardet, C. & Sicinski, P. The E4F protein is required for mitotic progression during embryonic cell cycles. Mol. Cell Biol. 24, 6467-6475 (2004).
-
(2004)
Mol. Cell Biol
, vol.24
, pp. 6467-6475
-
-
Le Cam, L.1
Lacroix, M.2
Ciemerych, M.A.3
Sardet, C.4
Sicinski, P.5
-
47
-
-
79955550445
-
A user's guide to the encyclopedia of DNA elements (ENCODE)
-
ENCODE Project Consortium
-
ENCODE Project Consortium, & Myers, R. M. et al. A user's guide to the encyclopedia of DNA elements (ENCODE). PLoS Biol. 9, e1001046 (2011).
-
(2011)
PLoS Biol
, vol.9
-
-
Myers, R.M.1
-
48
-
-
0034794417
-
Feeder-free growth of undifferentiated human embryonic stem cells
-
Xu, C. et al. Feeder-free growth of undifferentiated human embryonic stem cells. Nat. Biotechnol. 19, 971-974 (2001).
-
(2001)
Nat. Biotechnol
, vol.19
, pp. 971-974
-
-
Xu, C.1
-
49
-
-
28644444870
-
A GFP-based reporter system to monitor nonsense-mediated mRNA decay
-
Paillusson, A., Hirschi, N., Vallan, C., Azzalin, C. M. & Muhlemann, O. A GFP-based reporter system to monitor nonsense-mediated mRNA decay. Nucleic Acids Res. 33, e54 (2005).
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Paillusson, A.1
Hirschi, N.2
Vallan, C.3
Azzalin, C.M.4
Muhlemann, O.5
-
50
-
-
32044454232
-
HUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay
-
Wittmann, J., Hol, E. M. & Jack, H. M. hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay. Mol. Cell. Biol. 26, 1272-1287 (2006).
-
(2006)
Mol. Cell. Biol
, vol.26
, pp. 1272-1287
-
-
Wittmann, J.1
Hol, E.M.2
Jack, H.M.3
-
51
-
-
79953185370
-
Knockdown of T-cell intracellular antigens triggers cell proliferation, invasion and tumour growth
-
Izquierdo, J. M., Alcalde, J., Carrascoso, I., Reyes, R. & Ludena, M. D. Knockdown of T-cell intracellular antigens triggers cell proliferation, invasion and tumour growth. Biochem. J. 435, 337-344 (2011).
-
(2011)
Biochem. J.
, vol.435
, pp. 337-344
-
-
Izquierdo, J.M.1
Alcalde, J.2
Carrascoso, I.3
Reyes, R.4
Ludena, M.D.5
-
52
-
-
65449136284
-
TopHat: Discovering splice junctions with RNA-Seq
-
Trapnell, C., Pachter, L. & Salzberg, S.L. TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 25, 1105-1111 (2009).
-
(2009)
Bioinformatics
, vol.25
, pp. 1105-1111
-
-
Trapnell, C.1
Pachter, L.2
Salzberg, S.L.3
-
53
-
-
77952123055
-
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
-
Trapnell, C. et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat. Biotechnol. 28, 511-515 (2010).
-
(2010)
Nat. Biotechnol
, vol.28
, pp. 511-515
-
-
Trapnell, C.1
-
54
-
-
77958471357
-
Differential expression analysis for sequence count data
-
Anders, S. & Huber, W. Differential expression analysis for sequence count data. Genome Biol. 11, R106 (2010).
-
(2010)
Genome Biol
, vol.11
-
-
Anders, S.1
Huber, W.2
-
55
-
-
78650253763
-
Genome-wide Identification of polycomb-associated RNAs by RIP-seq
-
Zhao, J. et al. Genome-wide Identification of polycomb-associated RNAs by RIP-seq. Mol. Cell 40, 939-953 (2010).
-
(2010)
Mol. Cell
, vol.40
, pp. 939-953
-
-
Zhao, J.1
|