Simultaneous determination of matrine, oxysophocarpin and oxymatrine in rat plasma by HPLC-MS and its application in the pharmacokinetic study

Yaoxue Xuebao

Volumn 43, Issue 8, 2008, Pages 843-847

  Zhang, Lei ^a,b   Wang, Zhi Wei ^b,c   Lian, Jian Wei ^b   Zhou, Hao ^b   Chen, Xiao Hui ^b   Bi, Kai Shun ^b  

^a GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^c Tianjin Tasly Group Co Ltd   (China)

Author keywords

HPLC MS; Matrine; Oxymatrine; Oxysophocarpine; Plasma; Sanwu Huangqin decoction

Indexed keywords

ALKALOID; HERBACEOUS AGENT; MATRINE; OXYMATRINE; OXYSOPHOCARPINE; QUINOLIZINE DERIVATIVE;

ANIMAL; AREA UNDER THE CURVE; ARTICLE; BLOOD; CHEMISTRY; DRUG COMBINATION; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; MALE; MEDICINAL PLANT; METHODOLOGY; ORAL DRUG ADMINISTRATION; RAT; WISTAR RAT;

ADMINISTRATION, ORAL; ALKALOIDS; ANIMALS; AREA UNDER CURVE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG COMBINATIONS; DRUGS, CHINESE HERBAL; MALE; PLANTS, MEDICINAL; QUINOLIZINES; RATS; RATS, WISTAR; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 50249114700     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

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