Oxidative stress induces proliferation of colorectal cancer cells by inhibiting RUNX3 and activating the Akt signaling pathway

International Journal of Oncology

Volumn 43, Issue 5, 2013, Pages 1511-1516

  Kang, Kyoung Ah ^a   Kim, Ki Cheon ^a   Bae, Suk Chul ^b   Hyun, Jin Won ^a  

^a Jeju National University   (South Korea)

^b Institute for Tumor Research   (South Korea)

Author keywords

catenin; Akt; Cell proliferation; Colorectal cancer; Cyclin D1; Reactive oxygen species; Runt related transcription factor 3; Tumor suppressor gene

Indexed keywords

BETA CATENIN; CYCLIN D1; GLYCOGEN SYNTHASE KINASE 3BETA; HYDROGEN PEROXIDE; MESSENGER RNA; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR RUNX3;

ARTICLE; CANCER CELL; CELL GROWTH; CELL PROLIFERATION; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; UPREGULATION;

BETA CATENIN; BLOTTING, WESTERN; CELL NUCLEUS; CELL PROLIFERATION; COLORECTAL NEOPLASMS; CORE BINDING FACTOR ALPHA 3 SUBUNIT; CYCLIN D1; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYDROGEN PEROXIDE; IMMUNOENZYME TECHNIQUES; OXIDANTS; OXIDATIVE STRESS; PROMOTER REGIONS, GENETIC; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 84885081582     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2013.2102     Document Type: Article

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