Synthetic chondramide a analogues stabilize filamentous actin and block invasion by Toxoplasma gondii

Journal of Natural Products

Volumn 76, Issue 9, 2013, Pages 1565-1572

  Ma, Christopher I ^a   Diraviyam, Karthikeyan ^b   Maier, Martin E ^c   Sept, David ^b   Sibley, L David ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CHONDRAMIDE A; CYCLOPEPTIDE; F ACTIN; NATURAL PRODUCT; PROTEIN INHIBITOR; PYRIMETHAMINE; TYROSINE; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ARTICLE; ASSAY; BINDING SITE; DRUG SYNTHESIS; FLUORESCENCE MICROSCOPY; GROWTH; HOST CELL; IN VITRO STUDY; LIGHT SCATTERING; MOLECULAR DYNAMICS; NONHUMAN; PARASITE; POLYMERIZATION; SUBSTITUTION REACTION; TOXOPLASMA GONDII;

ACTIN CYTOSKELETON; ANIMALS; BINDING SITES; DEPSIPEPTIDES; MICROFILAMENT PROTEINS; PROTOZOAN PROTEINS; TOXOPLASMA;

EID: 84885079318     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np400196w     Document Type: Article

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