Zuonin B inhibits lipopolysaccharide-induced inflammation via downregulation of the ERK1/2 and JNK pathways in RAW264.7 macrophages

Evidence-based Complementary and Alternative Medicine

Volumn 2012, Issue , 2012, Pages

  Lee, Mee Young ^a,b   Yuk, Ji Eun ^a   Kwon, Ok Kyung ^a   Oh, Sei Ryang ^a   Lee, Hyeong Kyu ^a   Ahn, Kyung Seop ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Korea Institute of Oriental Medicine (KIOM)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; HERBACEOUS AGENT; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRIC OXIDE; PROSTAGLANDIN E2; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ZUONIN B;

ANIMAL CELL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BARK; CYTOTOXICITY; DAPHNE; DAPHNE GENKWA; DOWN REGULATION; ENZYME PHOSPHORYLATION; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SPLEEN CELL; TH2 CELL;

EID: 84863269963     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2012/728196     Document Type: Article

References (22)

1. Minagar A., Shapshak P., Fujimura R., Ownby R., Heyes M., Eisdorfer C., The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis Journal of the Neurological Sciences 2002 202 1-2 13 23 (Pubitemid 36153117)
2. Berenbaum F., Proinflammatory cytokines, prostaglandins, and the chondrocyte: mechanisms of intracellular activation Joint Bone Spine 2000 67 6 561 564 (Pubitemid 32014796)
3. Nathan C. F., Hibbs J. B. Jr., Role of nitric oxide synthesis in macrophage antimicrobial activity Current Opinion in Immunology 1991 3 1 65 70
4. Evans C. H., Nitric oxide: what role does it play in inflammation and tissue destruction Agents and Actions Supplements 1995 47 107 116
5. Yoon W. J., Ham Y. M., Yoo B. S., Moon J. Y., Koh J., Hyun C. G., Oenothera laciniata inhibits lipopolysaccharide induced production of nitric oxide, prostaglandin E2, and proinflammatory cytokines in RAW264.7 macrophages Journal of Bioscience and Bioengineering 2009 107 4 429 438
6. Goldsby R. A., Kindt T. J., Osborne B. A., Kuby J., Freeman W. H., Immunology Cytokines 2005 New York, NY, USA W.H. Freeman 296 297
7. Li Q., Verma I. M., NF- B regulation in the immune system Nature Reviews Immunology 2002 2 10 725 734
8. Karin M., Delhase M., The I B kinase (IKK) and NF- B: key elements of proinflammatory signalling Seminars in Immunology 2000 12 1 85 98 (Pubitemid 30114019)
9. Pearson G., Robinson F., Gibson T. B., Xu B. E., Karandikar M., Berman K., Cobb M. H., Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions Endocrine Reviews 2001 22 2 153 183 (Pubitemid 32458157)
10. Ajizian S. J., English B. K., Meals E. A., Specific inhibitors of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways block inducible nitric oxide synthase and tumor necrosis factor accumulation in murine macrophages stimulated with lipopolysaccharide and interferon- Journal of Infectious Diseases 1999 179 4 939 944 (Pubitemid 29159340)
11. Takeda K., Kaisho T., Akira S., Toll-like receptors Annual Review of Immunology 2003 21 335 376 (Pubitemid 37174535)
12. Park B. Y., Min B. S., Kwon O. K., Oh S. R., Ahn K. S., Kim T. J., Kim D. Y., Bae K., Lee H. K., Increase of caspase-3 activity by lignans from Machilus thunbergii in HL-60 cells Biological and Pharmaceutical Bulletin 2004 27 8 1305 1307 (Pubitemid 41701733)
13. Sawa T., Ohshima H., Nitrative DNA damage in inflammation and its possible role in carcinogenesis Nitric Oxide 2006 14 2 91 100 (Pubitemid 43165874)
14. Kimura H., Hokari R., Miura S., Shigematsu T., Hirokawa M., Akiba Y., Kurose I., Higuchi H., Fujimori H., Tsuzuki Y., Serizawa H., Ishii H., Increased expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in colonic mucosa of patients with active ulcerative colitis Gut 1998 42 2 180 187 (Pubitemid 28212172)
15. Turini M. E., DuBois R. N., Cyclooxygenase-2: a therapeutic target Annual Review of Medicine 2002 53 35 57 (Pubitemid 34177870)
16. Kundu J. K., Surh Y. J., Inflammation: gearing the journey to cancer Mutation Research 2008 659 1-2 15 30
17. Kim H. G., Yoon D. H., Lee W. H., Han S. K., Shrestha B., Kim C. H., Lim M. H., Chang W., Lim S., Choi S., Song W. O., Sung J. M., Hwang K. C., Kim T. W., Phellinus linteus inhibits inflammatory mediators by suppressing redox-based NF- B and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophage Journal of Ethnopharmacology 2007 114 3 307 315 (Pubitemid 350026213)
18. Roebuck K. A., Carpenter L. R., Lakshminarayanan V., Page S. M., Moy J. N., Thomas L. L., Stimulus-specific regulation of chemokine expression involves differential activation of the redox-responsive transcription factors AP-1 and NF- B Journal of Leukocyte Biology 1999 65 3 291 298 (Pubitemid 29109699)
19. Paul A., Wilson S., Belham C. M., Robinson C. J. M., Scott P. H., Gould G. W., Plevin R., Stress-activated protein kinases: activation, regulation and function Cellular Signalling 1997 9 6 403 410 (Pubitemid 27417165)
20. Surh Y. J., Chun K. S., Cha H. H., Han S. S., Keum Y. S., Park K. K., Lee S. S., Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF- B activation Mutation Research 2001 480-481 243 268 (Pubitemid 32744832)
21. Rao K. M. K., MAP kinase activation in macrophages Journal of Leukocyte Biology 2001 69 1 3 10 (Pubitemid 32095111)
22. Jiang J. X., Zhang Y., Ji S. H., Zhu P., Wang Z. G., Kinetics of mitogen-activated protein kinase family in lipopolysaccharide-stimulated mouse Kupffer cells and their role in cytokine production Shock 2002 18 4 336 341